Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Anticoagulants (1)
- Antiviral Agents (1)
- Child (1)
- Congenital heart disease (1)
- Contextual theory (1)
-
- Double-blind (1)
- Drug Interactions (1)
- Gadamer (1)
- Hermeneutics (1)
- Humans (1)
- Hypoplastic Left Heart Syndrome (1)
- Hypoplastic left heart syndrome (1)
- Influenza, Human (1)
- International Normalized Ratio (1)
- International normalized ratio (1)
- Male (1)
- Oseltamivir (1)
- Placebo (1)
- Placebo effect (1)
- Placebo response (1)
- Psychopharmacology (1)
- Theoretical (1)
- Thrombosis (1)
- Warfarin (1)
Articles 1 - 2 of 2
Full-Text Articles in Pharmaceutical Preparations
Oseltamivir-Warfarin Interaction In Hypoplastic Left Heart Syndrome: Case Report And Review., Jonathan B. Wagner, Susan M. Abdel-Rahman
Oseltamivir-Warfarin Interaction In Hypoplastic Left Heart Syndrome: Case Report And Review., Jonathan B. Wagner, Susan M. Abdel-Rahman
Manuscripts, Articles, Book Chapters and Other Papers
An 8-year-old boy with hypoplastic left heart syndrome with a previous history of thrombosis within the inferior vena cava receiving stable warfarin dosing for anticoagulation was diagnosed with influenza B. He was subsequently placed on oseltamivir therapy according to the Centers for Disease Control and Prevention clinical practice guidelines. During the hospitalization, his international normalized ratio steadily increased to supratherapeutic levels and returned to baseline after discontinuation of oseltamivir therapy. This case represents a drug-drug interaction that has not been previously reported in children or adolescents. An extensive review of the pharmacokinetic and pharmacodynamic literature did not uncover a definitive …
Utilization Of Placebo Response In Double-Blind Psychopharmacological Studies, Contextual Perspective, Margarita Olegovna Ashirova
Utilization Of Placebo Response In Double-Blind Psychopharmacological Studies, Contextual Perspective, Margarita Olegovna Ashirova
Antioch University Dissertations & Theses
Placebo response has been an elusive phenomenon in the fields of medicine, medical research, and psychology. Even though it has been heavily utilized as a comparator treatment in double-blind psychopharmacological studies, the reliable definition and consistent understanding of placebo response are missing. In this contextual exploration, I outlined the state of current placebo response research and variable rates of placebo response reported in double-blind studies. I identified the gap in the literature—lack of consistent understanding of placebo response—that has led to a waste of resources by the psychopharmacological research industry. Further, I compared and contrasted the current inconsistent Western medical …