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Articles 1 - 2 of 2
Full-Text Articles in Chemical Actions and Uses
Studies Of Amino Acid Mutations In Drug Resistance Of The Smo Protein, Eunice Wintona
Studies Of Amino Acid Mutations In Drug Resistance Of The Smo Protein, Eunice Wintona
UNO Student Research and Creative Activity Fair
Smoothened receptor (SMO) is a protein that in humans, is encoded by the SMO gene. A systemic mutation in its binding pocket helps predict the sensitivity of mutant proteins to different drugs. Known as a GPCR-like receptor, it is a component of the hedgehog signaling pathway; a pathway involved in body patterning and the regulation of adult stem cells. An uncontrolled or inappropriate activation of the Hedgehog pathway drives tumor progression in cancers and a number of birth defects. To achieve these goals, the molecular modeling software MOE was used to build small molecules and drug molecules like Vismodegib and …
The Shady Persecution Of Doping: Performance Enhancement Drugs And Meaning In Sport, Tyrin Antwan Stevenson
The Shady Persecution Of Doping: Performance Enhancement Drugs And Meaning In Sport, Tyrin Antwan Stevenson
Senior Projects Fall 2018
This project deals with the debate around performance enhancement drugs, utilizing a philosophical approach to meaning in sport to shed light on the topic.