Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (3)
- Medical Sciences (2)
- Musculoskeletal, Neural, and Ocular Physiology (2)
- Physiology (2)
- Sports Sciences (2)
-
- Biomechanical Engineering (1)
- Biomechanics and Biotransport (1)
- Biomedical Engineering and Bioengineering (1)
- Cell and Developmental Biology (1)
- Developmental Biology (1)
- Engineering (1)
- Exercise Physiology (1)
- Exercise Science (1)
- Kinesiology (1)
- Kinesiotherapy (1)
- Laboratory and Basic Science Research (1)
- Mechanical Engineering (1)
- Nervous System (1)
- Other Physiology (1)
- Rehabilitation and Therapy (1)
- Institution
- Keyword
-
- CTCF (1)
- Calcanealcuboid Distraction Arthrodesis (1)
- Cerebal Palsey (1)
- Chondrocytes (1)
- Delayed onset of muscle soreness (DOMS) (1)
-
- Differentiation (1)
- ECC (1)
- EIMD (1)
- Eccentric exercise (1)
- Elbow Flexors (1)
- Estrogen (1)
- Evans Osteotomy (1)
- Exoskeletal Prostheses (1)
- Extracellular matrix (ECM) (1)
- Flat foot (1)
- Foot and Ankle (1)
- Functional Limb Pathologies (1)
- H-reflex (1)
- High-soreness responders (1)
- Hindlimb (1)
- Hypertrophy (1)
- Limb Deficiency (1)
- MR (1)
- MTR (1)
- Micromass cultures (1)
- Postactivation Potentiation (1)
- Rate of Force Development (1)
- Reflex Potentiation (1)
- Sex Differences (1)
- Skeletal Muscle (1)
Articles 1 - 6 of 6
Full-Text Articles in Musculoskeletal System
Degrees Of Damage: Quantifying Male Vs. Female Exercise-Induced Muscle Damage Through Magnetization Transfer Ratios, Nicholai Michael Clausius Crawford
Degrees Of Damage: Quantifying Male Vs. Female Exercise-Induced Muscle Damage Through Magnetization Transfer Ratios, Nicholai Michael Clausius Crawford
Electronic Thesis and Dissertation Repository
No direct, quantitative, and non-invasive markers presently exist to assess exercise-induced muscle damage (EIMD). However, magnetization transfer ratios (MTR), an emerging measurement quantified via magnetic resonance imagery, provide more direct indication of muscle integrity following EIMD. This study compares and correlates the temporal pattern of the MTR to alternative indirect markers of EIMD in male vs. female populations, and subsequently establishes whether there are sex differences in biochemical activity during recovery. The antioxidant properties of estrogen hypothetically minimize muscle trauma, maintain membrane stability, and limit swelling resulting in heightened tissue integrity and resilience to EIMD. Six males and three females …
The Ctcf Chromatin Organizer Is Required For Hindlimb Development, Katherine L. Rabicki
The Ctcf Chromatin Organizer Is Required For Hindlimb Development, Katherine L. Rabicki
Electronic Thesis and Dissertation Repository
Mutations in chromatin organizer CTCF were identified in patients with intellectual disability and skeletal defects. Previous studies demonstrated that depletion of CTCF in murine limb mesenchyme results in apoptosis in the forelimb. The role of CTCF in the hindlimb, however, is unknown. My objective was to investigate effects of CTCF deletion on chondrogenesis and skeletal development in the hindlimb. In vitro wild-type micromass cultures demonstrate that chondrocyte gene expression is delayed in the hindlimb when compared to forelimbs. Embryonic CtcfFl/Fl;Prx1Cre mice were investigated, and qRT-PCR and histology were performed on limb buds and long bones. Results show that …
Research And Design Of Supportive Exoskeletal Aides For The Physically Challengedan Initial Investigation Into The Fundamentals And Rudiments Of Building A Full Body Exoskeletonmark, Mark Jacobs
Thinking Matters Symposium Archive
The purpose of this study is to provide methodology for designing exoskeletal prostheses targeted to specific pathologies associated with: Cerebral Palsy; Limb Deficiency; Spinal Pathologies; and Functional Limb Pathologies This study will extend to whole body exoskeletal structures. The project will be performed in conjunction with Shriner’s Hospital for Children in Springfield, Massachusetts; M.I.T. Bio-prosthetic Group; and finally, Massachusetts General Hospital Orthopedics Group. Further work will be done designing the necessary components for the project in Solidworks utilizing a 3D mannequin. The parts will then be fabricated using a CNC machine, first making them from foam insulation, then from wood …
The Role Of The Extracellular Matrix In Mediating Muscle Soreness, Karen L. Riska
The Role Of The Extracellular Matrix In Mediating Muscle Soreness, Karen L. Riska
Doctoral Dissertations
The goal of this dissertation was to examine the role of the extracellular matrix (ECM) in muscle soreness. Study 1 examined how the disruption of the ECM from a minor surgery (e.g. muscle biopsy) affected muscle soreness. Study 1 showed that soreness levels increased at 24 h post-biopsy compared to baseline and resolved within 96 h. However, the level of muscle soreness at 24 h post-biopsy (20 mm) was lower than that reported for performing a strenuous and naïve exercise (40–80 mm). These results will help review boards at institutions where muscle biopsies are performed understand how a muscle biopsy …
Muscular And Neural Contributions To Postactivation Potentiation, Brian Joseph Wallace
Muscular And Neural Contributions To Postactivation Potentiation, Brian Joseph Wallace
Theses and Dissertations--Kinesiology and Health Promotion
Muscle performance is partially a consequence of its recent contractile history. Postactivation potentiation (PAP) can occur after muscle contractions and leads to enhanced neuromuscular performance. The purpose of this dissertation was to explain the relationship between muscle factors (twitch potentiation, TP) and neural factors (reflex potentiation, RP) contributing to overall PAP following a non-fatiguing volitional muscle contraction. The tibial nerves of fifteen resistance trained volunteers (eleven men, four women) were stimulated intermittently at supramaximal (Mmax) and submaximal (Hmax) intensities for 20 minutes on separate days under three conditions: rest (Control); after a after a 10 second maximum voluntary isometric contraction …
Computational Modeling To Assess Surgical Procedures For The Treatment Of Adult Acquired Flatfoot Deformity, Brian A. Smith
Computational Modeling To Assess Surgical Procedures For The Treatment Of Adult Acquired Flatfoot Deformity, Brian A. Smith
Theses and Dissertations
Several surgically corrective procedures are considered to treat Adult Acquired Flatfoot Deformity (AAFD) patients, relieve pain, and restore function. Procedure selection is based on best practices and surgeon preference. Recent research created patient specific models of Adult Acquired Flatfoot Deformity (AAFD) to explore their predictive capabilities and examine effectiveness of the surgical procedure used to treat the deformity. The models’ behavior was governed solely by patient bodyweight, soft tissue constraints, and joint contact without the assumption of idealized joints. The current work expanded those models to determine if an alternate procedure would be more effective for the individual. These procedures …