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Full-Text Articles in Musculoskeletal System
Novel Architecture Of Costal Cartilage And Implications In Chest Wall Deformities, Anthony J. Asmar
Novel Architecture Of Costal Cartilage And Implications In Chest Wall Deformities, Anthony J. Asmar
Biological Sciences Theses & Dissertations
Costal cartilage is a type of hyaline cartilage that forms rod-like structures that connect the ribs to the sternum. Deformation of costal cartilage is observed in the chest wall deformities, pectus excavatum and pectus carinatum. Pectus excavatum involves a sternal displacement causing a depression of the chest while pectus carinatum causes a protrusion of the chest. As costal cartilage is not a widely studied tissue, this leaves little knowledge into possible factors involved in the pathogenesis of pectus deformities. Costal cartilage in these deformities has been described as being weakened and may implicate proteoglycans which play an important role in …
Efficacy Of AllowashTm Solution In Solubilization Of Bone Marrow, Alyce Marie Linthurst
Efficacy Of AllowashTm Solution In Solubilization Of Bone Marrow, Alyce Marie Linthurst
Biological Sciences Theses & Dissertations
LifeNet currently cleans allograft bone utilizing AllowashTM Technology, which encompasses the use of a closed continuous circulation chamber to remove bone marrow by flushing it with AllowashTM Solution for a prescribed time and temperature after which, it is rinsed with various solutions to remove residual detergent that could be toxic to the recipient. A portion of this process employs AllowashTM Solution to improve the solubilization and removal of protein and cellular elements in the red bone marrow. This study examines the effectiveness of AllowashTM Solution in comparison to its component detergents Nonidet P40, Nonoxynol 9 and …
Osteoinductivity Of Demineralized Bone: A Quantitative In Vitro Assessment, Yihong Zheng
Osteoinductivity Of Demineralized Bone: A Quantitative In Vitro Assessment, Yihong Zheng
Biological Sciences Theses & Dissertations
Acid demineralized bone (DMB) implanted in extraosseous sites induces bone formation. In vivo studies have shown that DMB stimulates the differentiation of mesenchymal cells into osteogenic cells. In this study an in vitro system was developed to demonstrate the osteoinductivity of DMB quantitatively. This in vitro working system was used to assess the osteoinductivity of variously processed DMB products as a means to evaluate their processing protocols. A human dermal fibroblastic (HDF) cell line was initiated from tissue explants as a working model, along with a human periosteal (HPO) cell line as a control. Ground DMB processed by LifeNet Transplant …