Musculoskeletal System Commons^™

Validation Of Rotoscoping Method For Two-Marker Bones In The Alligator Forearm, Nina Pitre

Biology Student Scholarship

Nina Pitre ’22
Majors: Biology and Psychology
Faculty Mentor: Dr. David Baier, Biology

XROMM methods "re-animate" 3D skeletal motion of living animals by aligning digital bone models to X-ray videos. Surgically implanted markers permit automatic alignment of bone models if three or more markers are used. However, one of our specimens only had two markers implanted. These bones could be automatically positioned and partially oriented using the two markers, but then required manual alignment to the X-ray images to orient about the axis passing between the two markers. Here, we validated the method by digitally removing a marker from a …

Connexin 43 Contributes To Phenotypic Variability Of The Mouse Skull, Elizabeth Jewlal

Electronic Thesis and Dissertation Repository

The purpose of this study was to determine whether connexin 43 (Cx43) contributes to craniofacial phenotypic variability. Skull shape and variation were compared within and among two heterozygous mutant mouse models (G60S/+ and I130T/+) that exhibit different levels of Cx43 channel function when compared to their wildtype counterparts (~80% and ~50% reduction in function, respectively). Results indicated mutants have significant differences in skull shape compared to wildtype littermates. Similar patterns of shape difference were found in both mutants. Increased skull shape variation and a disruption in the covariation of skull structures were observed in G60S/+ mutants only. These results show …