Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Dayton (74)
- Selected Works (63)
- SUNY College Cortland (15)
- Chapman University (8)
- SelectedWorks (6)
-
- City University of New York (CUNY) (5)
- Old Dominion University (5)
- University of Nevada, Las Vegas (5)
- Western University (5)
- University of Kentucky (4)
- University of Nebraska at Omaha (4)
- The University of Akron (3)
- University of Arkansas, Fayetteville (3)
- University of Massachusetts Amherst (3)
- Lesley University (2)
- Loma Linda University (2)
- Northern Michigan University (2)
- University of Nebraska - Lincoln (2)
- University of South Florida (2)
- Wilfrid Laurier University (2)
- Bard College (1)
- Bridgewater College (1)
- Cedarville University (1)
- Claremont Colleges (1)
- East Tennessee State University (1)
- Edith Cowan University (1)
- Fort Hays State University (1)
- Georgia Southern University (1)
- Himmelfarb Health Sciences Library, The George Washington University (1)
- Liberty University (1)
- Keyword
-
- Breast cancer (11)
- Exercise (11)
- Lymphedema (9)
- Stress (8)
- Tibia (8)
-
- Heat Shock Proteins (7)
- Psychometrics (7)
- Biomechanics (6)
- Gait (6)
- Limb function among breast cancer survivors (6)
- Oncology rehabilitation (6)
- DXA (5)
- Fitness (5)
- Osteocalcin (5)
- Yoga (5)
- 3-pt bending test (4)
- Aging (4)
- Arm function (4)
- Deoxypyridinoline (4)
- Diabetes (4)
- FEA (4)
- Training (4)
- Allometric scaling (3)
- Electromyography (3)
- Modeling (3)
- Patient care (3)
- Rehabilitation (3)
- Running (3)
- Self-care (3)
- Skeletal muscle (3)
- Publication Year
- Publication
-
- Physical Therapy Faculty Publications (55)
- Health and Sport Science Faculty Publications (19)
- Master's Theses (16)
- Mary Insana Fisher (13)
- Paul M. Vanderburgh (11)
-
- Jamie Melling (10)
- C. Jayne Brahler (9)
- Daniel Leib (6)
- Biology, Chemistry, and Environmental Sciences Faculty Articles and Research (5)
- Electronic Thesis and Dissertation Repository (5)
- Anne R. Crecelius (4)
- Betsy Donahoe-Fillmore (4)
- Electronic Theses and Dissertations (4)
- Human Movement Sciences Faculty Publications (4)
- Interdisciplinary Research Scholarship Day (4)
- Philip A. Anloague (4)
- Harold L. Merriman (3)
- Health Sciences and Kinesiology Faculty Articles (3)
- Publications and Research (3)
- UNO Student Research and Creative Activity Fair (3)
- Williams Honors College, Honors Research Projects (3)
- Doctoral Dissertations (2)
- Expressive Therapies Capstone Theses (2)
- Health, Human Performance and Recreation Undergraduate Honors Theses (2)
- Loma Linda University Electronic Theses, Dissertations & Projects (2)
- Masters Theses (2)
- Theses and Dissertations (Comprehensive) (2)
- Theses and Dissertations--Kinesiology and Health Promotion (2)
- USF Tampa Graduate Theses and Dissertations (2)
- ASPIRE 2024 (1)
- Publication Type
- File Type
Articles 1 - 30 of 239
Full-Text Articles in Anatomy
The Anatomical Embodiment Of Morning Routines In The Reduction Of Anxiety: An Intervention, Natalie Wright
The Anatomical Embodiment Of Morning Routines In The Reduction Of Anxiety: An Intervention, Natalie Wright
Expressive Therapies Capstone Theses
The topic under investigation is whether physically embodying a morning routine that was designed through the lens of Laban Bartenieff Movement Analysis (LBMA) will reduce daily symptoms of individuals diagnosed with Generalized Anxiety Disorder.
Since morning routines play a significant part in one’s preparation for the day, I created an individualized LBMA morning routine for a specific client to embody. In addition to the routine, the client documented the process of their anxiety levels on a weekly basis. This client was a white, female, 19-year-old, lesbian college student who was previously diagnosed with Generalized Anxiety Disorder (GAD). The movement analysis …
Cortisol Production In Female Soccer Players, Katelyn Seagraves
Cortisol Production In Female Soccer Players, Katelyn Seagraves
ASPIRE 2024
Cortisol is released from the adrenal glands when there is an apparent stressor. Exercise, while beneficial, is seen as stress to the body and incites increased cortisol release. Cortisol is known to increase with exercise, and higher-intensity exercise tends to raise cortisol more compared to lower intensities. However, less is known about interval training and cortisol concentrations.
This review of literature dives into the background of cortisol: how it's produced, what systems it regulates, and differences in production based on gender, stressors, exercise intensity, and duration. This paper identifies some knowledge gaps and links training intensities in soccer to cortisol …
Body Movement Syllabus - The City College Of New York - Department Of Theatre - Prof Timothy Allen, Timothy J. Allen
Body Movement Syllabus - The City College Of New York - Department Of Theatre - Prof Timothy Allen, Timothy J. Allen
Open Educational Resources
This course will explore three modules of learning.
-
Anatomy and Psycho-Physical Centering, will explore two foundations: (1) the start of our research and practical application of the human anatomy in regards to how our body moves; and (2) your ability to tune into movement centers within the body by utilizing Chakra as a guiding study. Please note: Anatomy will be a continuous study throughout the entire semester.
-
THE SECOND MODULE, Partnered Connection, will focus on partnering with lifts, counter-balances, falls, and rolls that will build to a partnering sequence of the tools presented.
-
THE LAST MODULE, Global Archetypes, …
Role Of Fat Content On The Structure And Function Of Human Skeletal Muscle, Joseph A. Gordon Iii
Role Of Fat Content On The Structure And Function Of Human Skeletal Muscle, Joseph A. Gordon Iii
Doctoral Dissertations
Muscle size does not fully explain variations in muscle strength. Fat content has been implicated in muscle weakness, though this relationship remains unclear. The relationship between fat and strength may vary between scales (e.g., cellular, organ, and organism). The goal of this dissertation was to clarify the role of fat in the structure and function of muscle using in vitro and in vivo techniques across multiple scales in adults 21-45 years old. Study 1 tested the agreement of intramyocellular lipid (IMCL) content between oil red o (ORO) and magnetic resonance spectroscopy (MRS) techniques. These measures of IMCL were also compared …
Resistance Training And Running Performance And Economy: A Literature Review, James Bottrill
Resistance Training And Running Performance And Economy: A Literature Review, James Bottrill
University Honors Theses
Running performance is largely determined by maximal oxygen uptake (VO2 max), velocity at VO2 max, fractional utilisation of VO2 max and running economy. Running economy is relatively under-researched and could be improved by resistance training because of its neuromuscular underpinnings. However, existing research on this topic is quite unorganised and inconclusive and is yet to prove a direct linkage between resistance training, running economy and performance. This literature review aimed to provide an organised overview of the existing literature, identify and address confounding variables and provide recommendations for future research. A search for studies was conducted via …
The Effect Of Running On The Onset And Development Of Osteoarthritis, Jordan Hekman
The Effect Of Running On The Onset And Development Of Osteoarthritis, Jordan Hekman
Senior Honors Theses
Osteoarthritis is a prominent and debilitating form of joint disease characterized by pain and deterioration of the articular cartilage and other tissues in the affected joint. Research has identified a variety of risk factors for osteoarthritis, including age, obesity, gender, previous injury, and occupation. The relationship between running and osteoarthritis is a topic of particular interest because of the prevalence of running as a simple and physiologically beneficial form of exercise. Increasing evidence suggests that recreational running has at worst no effect and at best a protective effect on joint and articular cartilage health in contrast to high-intensity professional/elite-level running …
Plantar Flexor Dynamic Contractile Rates Are Not Dependent On Calcaneal Tendon Stiffness, Sohum Kulkarni
Plantar Flexor Dynamic Contractile Rates Are Not Dependent On Calcaneal Tendon Stiffness, Sohum Kulkarni
Electronic Thesis and Dissertation Repository
The ability to rapidly generate muscular torque and velocity is important in specialized activities and daily tasks of living. Tendon stiffness is one factor in the neuromuscular system that influences musculoskeletal torque transmission. Previous studies have reported weak-to-moderate correlations between tendon stiffness and rate of torque development (RTD). However, these correlations have been reported only for isometric contractions which may not be relevant to contractions involving joint rotation (i.e., dynamic). The purpose was to investigate the effect of calcaneal tendon stiffness on the dynamic rates of torque (RTD) and velocity (RVD) development in plantar flexor muscles. Young adult males (n=13) …
How Some Arboreal Salamanders (Genus Aneides) Jump, Glide, And Generate Lift, Christian E. Brown
How Some Arboreal Salamanders (Genus Aneides) Jump, Glide, And Generate Lift, Christian E. Brown
USF Tampa Graduate Theses and Dissertations
The jumping and subsequent aerial behaviors of arboreal lungless salamanders (genus Aneides) had never been investigated or described. The aims of this research were to (1) compare jumping performance within the family Plethodontidae with a special focus on arboreal species from genus Aneides, (2) describe the biomechanics and kinematics of aerial behaviors after a jump or extended fall, and (3) model airflow over the morphology of the most aerially adept salamanders to investigate if they are capable of generating lift. First, I recorded salamanders jumping, locomoting vertically, dropping, and flying in a vertical wind tunnel. Then, I laser-scanned and reconstructed …
The Effects Of Demographics And Risk Factors On The Morphological Characteristics Of Human Femoropopliteal Arteries, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy
The Effects Of Demographics And Risk Factors On The Morphological Characteristics Of Human Femoropopliteal Arteries, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy
UNO Student Research and Creative Activity Fair
Background: Disease of the lower extremity arteries (Peripheral Arterial Disease, PAD) is associated with high morbidity and mortality. During disease development, the arteries adapt by changing their diameter, wall thickness, and residual deformations, but the effects of demographics and risk factors on this process are not clear.
Methods: Superficial femoral arteries from 736 subjects (505 male, 231 female, 12 to 99 years old, average age 51±17.8 years) and the associated demographic and risk factor variables were used to construct machine learning (ML) regression models that predicted morphological characteristics (diameter, wall thickness, and longitudinal opening angle resulting from the …
The Top 50 Most Cited Articles On The Medial Patellofemoral Ligament (Mpfl): A Bibliometric Analysis, Varag Abed, Alex Duvall, Jonathan D. Rexroth, Alyssa Goodwin, Joseph Liu, Austin Stone
The Top 50 Most Cited Articles On The Medial Patellofemoral Ligament (Mpfl): A Bibliometric Analysis, Varag Abed, Alex Duvall, Jonathan D. Rexroth, Alyssa Goodwin, Joseph Liu, Austin Stone
Medical Student Research Symposium
Objectives: To determine which original articles on the topic of the medial patellofemoral ligament (MPFL) have been cited the most in the literature utilizing a bibliometric approach. Secondarily, to determine temporal trends between article types.
Methods: Articles on the topic of the MPFL were identified by utilizing the Web of Science Database. The search yielded 1,596 results and the top 50 cited original articles were collected for further analysis. The following information was gathered for all included articles: title, first author's name, journal name, year of publication, impact factor of the journal in 2021, total number of citations of the …
The Accuracy Of Recreational Athletes In Self Detecting Ventilation Threshold During A Maximal Exercise Test, Andrew Biegner
The Accuracy Of Recreational Athletes In Self Detecting Ventilation Threshold During A Maximal Exercise Test, Andrew Biegner
Williams Honors College, Honors Research Projects
INTRODUCTION: Ventilatory threshold (VT) is where minute ventilation (VE) increases nonlinearly with increasing exercise intensity. Prior studies have shown that subjects can recognize VT by changes in breathing during exercise. Teaching recreational athletes to use VT as a training method could result in better quality training. PURPOSE: Determine if recreational athletes can accurately perceive changes in ventilation associated with VT during maximal exercise testing. METHODS: Subjects were recruited (n=20, age= 20.5 ± 1.7 yrs.) to participate in the study. Subjects performed a modified maximal treadmill protocol with gas analysis. Subjects indicated when they noticed a considerable change …
Short-Term Removal Of Exercise Impairs Glycemic Control In Older Adults: A Randomized Trial, Leryn J. Reynolds, Troy M. Williams, Joel E. Harden, Hannah M. Twiddy, Monica L. Kearney
Short-Term Removal Of Exercise Impairs Glycemic Control In Older Adults: A Randomized Trial, Leryn J. Reynolds, Troy M. Williams, Joel E. Harden, Hannah M. Twiddy, Monica L. Kearney
Human Movement Sciences Faculty Publications
Postprandial glycemia (PPG) predicts cardiovascular disease, and short-term physical inactivity increases PPG in young, active adults. Whether this occurs in older, active adults who may be more prone to bouts of inactivity is unknown. This study determined if postprandial interstitial glucose (PPIG) was impaired in active older adults following the removal of exercise for 3 days (NOEX) compared to active young adults. In this randomized, crossover study, 11 older (69.1 ± 1.9 years) and 9 young (32.8 ± 1.8 years) habitually active (≥90 min/week of exercise) adults completed 3-days of NOEX and 3-days of normal habitual exercise (EX), separated by …
Amphisbaenian Head Movement And Burrowing Forces In Damp Granular Media, Jacob Newell
Amphisbaenian Head Movement And Burrowing Forces In Damp Granular Media, Jacob Newell
Williams Honors College, Honors Research Projects
Damp granular media is a difficult environment to study because it is both practically complex and it lacks equations which fully describe its behavior. In this study, an oscillatory lateral head movement and its effects while penetrating damp granular media were tested using a robophysical model. This experimental research was inspired by the burrowing behavior of the clade Amphisbaenia, a group of usually limbless squamates that employ a variety of different burrowing behaviors, but it can apply to a wide range of burrowers. This research could help with both human burrowing technologies and the further investigation of animal behaviors.
Clinical Practice Guidelines: The Road Map To Better Care, Mary I. Fisher
Clinical Practice Guidelines: The Road Map To Better Care, Mary I. Fisher
Physical Therapy Faculty Publications
Systematic reviews and meta-analyses are important tools in translating research evidence into clinical practice as they critically evaluate and summarize the body of evidence on clinical topics. Clinicians can use these studies to quickly survey the current literature base to increase understanding of a clinical diagnosis they make, with the intent of using this information to improve their clinical practice. A well-written systematic review or meta-analysis, with critical evaluation of study quality, is then that Cliffs Note version of what to know and what to do. Therefore, with the proliferation of systematic reviews and meta-analyses, we should see a corresponding …
Screening And Assessment Of Cancer-Related Fatigue: An Executive Summary And Road Map For Clinical Implementation, Joy C. Cohn, Shana Harrington, Jeannette Lee, Daniel Malone, Mary I. Fisher
Screening And Assessment Of Cancer-Related Fatigue: An Executive Summary And Road Map For Clinical Implementation, Joy C. Cohn, Shana Harrington, Jeannette Lee, Daniel Malone, Mary I. Fisher
Physical Therapy Faculty Publications
Background: Cancer-related fatigue (CRF) prevalence is reported as high as 90%. Cancer-related fatigue is multidimensional and associated with lower health-related quality of life. Effective screening and assessment are dependent upon use of valid, reliable, and clinically feasible measures. This Executive Summary of the Screening and Assessment of Cancer-related Fatigue Clinical Practice Guideline provides recommendations for best measures to screen and assess for CRF based on the quality and level of evidence, psychometric strength of the tools, and clinical utility.
Methods: After a systematic review of the literature, studies evaluating CRF measurement tools were assessed for quality; data extraction included psychometrics …
Screening And Assessment Of Cancer-Related Fatigue: A Clinical Practice Guideline For Health Care Providers, Mary I. Fisher, Joy C. Cohn, Shana Harrington, Jeannette Lee, Daniel Malone
Screening And Assessment Of Cancer-Related Fatigue: A Clinical Practice Guideline For Health Care Providers, Mary I. Fisher, Joy C. Cohn, Shana Harrington, Jeannette Lee, Daniel Malone
Physical Therapy Faculty Publications
Cancer-related fatigue (CRF) is the most common side effect of cancer treatment. Regular surveillance is recommended, but few clinical practice guidelines transparently assess study bias, quality, and clinical utility in deriving recommendations of screening and assessment methods. The purpose of this clinical practice guideline (CPG) is to provide recommendations for the screening and assessment of CRF for health care professions treating individuals with cancer. Following best practices for development of a CPG using the Appraisal of Guidelines for Research and Evaluation (AGREE) Statement and Emergency Care Research Institute (ECRI) Guidelines Trust Scorecard, this CPG included a systematic search of the …
Trustworthiness And Quality In Research For Clinical Application, Mary I. Fisher
Trustworthiness And Quality In Research For Clinical Application, Mary I. Fisher
Physical Therapy Faculty Publications
No abstract provided.
Bodyverse, Colin B. Stilwell
Bodyverse, Colin B. Stilwell
Theses and Dissertations
This paper supports the MFA dance thesis film BodyVerse. Exploring the intertwining relationship of body systems with the natural world, it brings somatic principles such as Body Mind Centering and dance improvisation together with film legacies and digital platforms.
Impact Forces And Patterns Of Axonal Injury Differ Between Two Models Of Tbi, Edward Lai, David M Devilbiss
Impact Forces And Patterns Of Axonal Injury Differ Between Two Models Of Tbi, Edward Lai, David M Devilbiss
Rowan-Virtua Research Day
Traumatic brain injury (TBI) affects approximately 3.8 million Americans a year and results in complex neuropathological and neurocognitive sequelae. Animal models of TBI attempt to replicate the impact forces and pathology of injury in humans. However, in these models, the forces generated at the time of impact are poorly understood. Nonetheless, a variety of shear and strain forces generated at the time of impact can produce diffuse axonal injury. Injury to axons and neurons across a variety of brain regions resulting from axonal injury underlies the cognitive and behavioral impairments observed after TBI. Three critical brain regions, the corpus callosum …
Ankle Dorsiflexion Range Of Motion, Dynamic Balance, And Static Balance In Division Iii Collegiate Gymnasts, Emily Sabo
Ankle Dorsiflexion Range Of Motion, Dynamic Balance, And Static Balance In Division Iii Collegiate Gymnasts, Emily Sabo
Master's Theses
Introduction: Artistic gymnastics is a demanding sport composed of high intensity activities. Decreased range of motion can increase the risk of lower extremity injury due to the inability to disperse forces properly upon landing. Landing from a height demands dynamic balance, which may be influenced by ankle range of motion. Due to the complexity of the sport, identifying potential deficits at the ankle could lead to the development of injury prevention programs. Purpose: The purpose of this study is to investigate if correlations exist between active ankle dorsiflexion range of motion (AROM) and static balance and/or AROM and dynamic balance …
Self-Reported Arm Function Is Associated With Stress And Fear Of Physical Activity Among Women Treated For Breast Cancer, Mary Insana Fisher, Anne Fleischer, Kimberly Ulmer, Megan Mcclure, Renee Waldron, Lynn Difede
Self-Reported Arm Function Is Associated With Stress And Fear Of Physical Activity Among Women Treated For Breast Cancer, Mary Insana Fisher, Anne Fleischer, Kimberly Ulmer, Megan Mcclure, Renee Waldron, Lynn Difede
Physical Therapy Faculty Publications
Background: Self-reported upper extremity function and objective measures are not strongly associated with each other in women treated for breast cancer (BC). It is not known if the lack of relationship between self-reported upper extremity function and objective measurements may be influenced by perceived levels of stress and fear of physical activity. The purpose of this study was to investigate the relationships between self-reported upper extremity function and the following: perceived stress levels (PS), fear of physical activity (FPA), health-related quality of life (HRQOL), and objective measures of upper extremity function among women treated for BC.
Methods: This cross-sectional observational …
Mountains Of Evidence, Mary I. Fisher
Mountains Of Evidence, Mary I. Fisher
Physical Therapy Faculty Publications
No abstract provided.
Knowledge Regarding Cancer-Related Fatigue: A Survey Of Physical Therapists And Individuals Diagnosed With Cancer, Shana Harrington, Mary Insana Fisher, Jeannette Lee, Joy C. Cohn, Daniel Malone
Knowledge Regarding Cancer-Related Fatigue: A Survey Of Physical Therapists And Individuals Diagnosed With Cancer, Shana Harrington, Mary Insana Fisher, Jeannette Lee, Joy C. Cohn, Daniel Malone
Physical Therapy Faculty Publications
Background: Cancer-related fatigue (CRF) is a common side effect and remains under-diagnosed. Screening of CRF by physical therapists (PTs) and patient perspectives of their experiences has not been comprehensively examined.
Purpose: To survey PTs to understand the frequency of CRF screening, and to assess the knowledge and experiences of survivors as it relates to CRF.
Methods: Two separate electronic surveys developed by the authors were distributed. One targeted oncology PTs, the other for adult survivors of cancer.
Results: Of the 199 PT respondents, 36% reported screening for CRF at every encounter. Screening included interviews (46%) and/or standardized questionnaires (37%). The …
Design And Development Of Software With A Graphical User Interface To Display And Convert Multiple Microscopic Histology Images, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy
Design And Development Of Software With A Graphical User Interface To Display And Convert Multiple Microscopic Histology Images, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy
UNO Student Research and Creative Activity Fair
Histological images are widely used to assess the microscopic anatomy of biological tissues. Recent advancements in image analysis allow the identification of structural features on histological sections that can help advance medical device development, brain and cancer research, drug discovery, vascular mechanobiology, and many other fields. Histological slide scanners create images in SVS and TIFF formats that were designed to archive image blocks and high-resolution textual information. Because these formats were primarily intended for storage, they are often not compatible with conventional image analysis software and require conversion before they can be used in research. We have developed a user-friendly …
Forty Years, Mary I. Fisher
Forty Years, Mary I. Fisher
Physical Therapy Faculty Publications
No abstract provided.
Longitudinal Changes Of Cardiorespiratory Fitness Performance In High School: Association With Individual And School-Based Variables, Xihe Zhu, Justin A. Haegele, Jinting Shao, Summer Davis
Longitudinal Changes Of Cardiorespiratory Fitness Performance In High School: Association With Individual And School-Based Variables, Xihe Zhu, Justin A. Haegele, Jinting Shao, Summer Davis
Human Movement Sciences Faculty Publications
This study aimed to model adolescents’ cardiorespiratory fitness performance change trajectories longitudinally across high school years and its relation to school- and individual/student-level factors. We employed hierarchical linear modeling to examine longitudinal cardiorespiratory fitness performance changes, as measured by the progressive aerobic capacity endurance run (PACER), over the years, between sexes, and in association with the school-level variables. Participants were 76,227 adolescents from 80 high schools in the mid-Atlantic region of the United States. School-level academic performance (SAP), the percent of students eligible for free and reduced-price meals (FARM), and physical education student-faculty ratio were obtained with permission from the …
The Ironman, Mary I. Fisher
The Ironman, Mary I. Fisher
Physical Therapy Faculty Publications
No abstract provided.
Coordination Variability And Injury Risk In Experienced Collegiate Dancers, Emily Klinkman
Coordination Variability And Injury Risk In Experienced Collegiate Dancers, Emily Klinkman
All NMU Master's Theses
Dance is a sport that places a number of physical demands upon the human body, and injuries are a common occurrence in the sport. While it has not yet been linked to dance-related injury, coordination variability (CV) is a measure of how much movement strategy changes between repetitions of a task and low levels of CV have been linked to injury in other sports. This study aimed to determine the relationship between CV and dance injury in collegiate dancers. Eight (8) undergraduate student subjects were recruited from the dance major and minor, BFA major and minor, and recreational dancers who …
The Onset Of Exercise-Associated Hyponatremia And Individual Differences In Inappropriate Arginine Vasopressin Excretion: A Review Of Proposed Mechanisms, Michelle Stehman, Stephen A. Maris
The Onset Of Exercise-Associated Hyponatremia And Individual Differences In Inappropriate Arginine Vasopressin Excretion: A Review Of Proposed Mechanisms, Michelle Stehman, Stephen A. Maris
Topics in Exercise Science and Kinesiology
Topics in Exercise Science and Kinesiology Volume 2: Issue 1, Article 10, 2021. Exercise-associated hyponatremia (EAH) has been reported to develop during endurance events such as triathlons and marathons. As these events become more popular, the incidence of developing EAH also increases. The development of EAH is commonly associated with the overconsumption of hypotonic fluids such as water and tends to be more prevalent in females. There is also evidence to suggest the inappropriate secretion of arginine vasopressin (AVP) leading to water retention may predispose an individual for developing EAH, especially when coupled with the overconsumption of fluids. Recent research …
A Systematic Review And Meta-Analysis On The Efficacy Of Stem Cell Therapy On Bone Brittleness In Mouse Models Of Osteogenesis Imperfecta, Lauren Battle, Shoshana Yakar, Alessandra Carriero
A Systematic Review And Meta-Analysis On The Efficacy Of Stem Cell Therapy On Bone Brittleness In Mouse Models Of Osteogenesis Imperfecta, Lauren Battle, Shoshana Yakar, Alessandra Carriero
Publications and Research
There is no cure for osteogenesis imperfecta (OI), and current treatments can only partially correct the bone phenotype. Stem cell therapy holds potential to improve bone quality and quantity in OI. Here, we conduct a systematic review and meta-analysis of published studies to investigate the efficacy of stem cell therapy to rescue bone brittleness in mouse models of OI. Identified studies included bone marrow, mesenchymal stem cells, and human fetal stem cells. Effect size of fracture incidence, maximum load, stiffness, cortical thickness, bone volume fraction, and raw engraftment rates were pooled in a random-effects meta-analysis. Cell type, cell number, injection …