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Full-Text Articles in Surgical Procedures, Operative

Multicolor Fluorescence Guided Surgery For Head And Neck Cancer, Dani Szafran-Reeder Jun 2022

Multicolor Fluorescence Guided Surgery For Head And Neck Cancer, Dani Szafran-Reeder

University Honors Theses

This project aims to take a novel, NIR nerve-specific fluorophore LGW05-75⁴ and test its compatibility with a tumor-targeting affibody molecule, ABY-029⁶ that has been labeled with IRDye800CW. The overall goal is to show that these two molecules can be co-administered to show the nerves and tumor cells in real-time to better assist surgeons in a full resection while avoiding iatrogenic nerve damage.


Effectiveness Of Stabilized Hypochlorous Acid In Acute Peritonitis Treatment: A Murine Surgical Study, Benjamin Michael Pomeroy Jan 2022

Effectiveness Of Stabilized Hypochlorous Acid In Acute Peritonitis Treatment: A Murine Surgical Study, Benjamin Michael Pomeroy

MSU Graduate Theses

Peritonitis is an inflammatory condition affecting the mesothelial cells that line the peritoneal cavity and is commonly induced by bowel perforations. This medical emergency is treated through antibiotic therapy and surgical intervention followed by tissue irrigation (lavage). Acute treatments aim to remove the bacterial burden, however recurring peritoneal infections occur at high rates and contribute to patient morbidity. These recurring infections are likely due to the inability of lavage solutions to remove the entire massive intra-abdominal bacterial load due to intestinal perforation. Numerous antiseptic solutions and antibiotic additives have been evaluated in their ability to improve source control by abdominal …