Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Diseases (2)
- Life Sciences (2)
- Animal Diseases (1)
- Bacterial Infections and Mycoses (1)
- Cancer Biology (1)
-
- Cell and Developmental Biology (1)
- Community Health and Preventive Medicine (1)
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
- Endocrine System Diseases (1)
- Epidemiology (1)
- Immune System Diseases (1)
- Immunity (1)
- Immunology and Infectious Disease (1)
- Immunopathology (1)
- Large or Food Animal and Equine Medicine (1)
- Medical Sciences (1)
- Microbiology (1)
- Organismal Biological Physiology (1)
- Physiological Processes (1)
- Physiology (1)
- Public Health (1)
- Systems and Integrative Physiology (1)
- Veterinary Medicine (1)
- Publication
- Publication Type
Articles 1 - 3 of 3
Full-Text Articles in Diagnosis
Evaluation Of Circulating Mirnas During Late Pregnancy In The Mare, Shavahn C. Loux, Kirsten E. Scoggin, Jason E. Bruemmer, Igor F. Canisso, Mats H. T. Troedsson, Edward L. Squires, Barry A. Ball
Evaluation Of Circulating Mirnas During Late Pregnancy In The Mare, Shavahn C. Loux, Kirsten E. Scoggin, Jason E. Bruemmer, Igor F. Canisso, Mats H. T. Troedsson, Edward L. Squires, Barry A. Ball
Veterinary Science Faculty Publications
MicroRNAs (miRNAs) are small, non-coding RNAs which are produced throughout the body. Individual tissues tend to have a specific expression profile and excrete many of these miRNAs into circulation. These circulating miRNAs may be diagnostically valuable biomarkers for assessing the presence of disease while minimizing invasive testing. In women, numerous circulating miRNAs have been identified which change significantly during pregnancy-related complications (e.g. chorioamnionitis, eclampsia, recurrent pregnancy loss); however, no prior work has been done in this area in the horse. To identify pregnancy-specific miRNAs, we collected serial whole blood samples in pregnant mares at 8, 9, 10 m of gestation …
Discovery Of Novel Diagnostic Biomarkers On Prostate Tumor Microparticles For Discriminating Between Low And High Risk Prostate Cancer And Improving Prostate Cancer Screening, Sabine Brett
Electronic Thesis and Dissertation Repository
There are few protein-based biomarkers to accurately distinguish between patients with low risk prostate cancer from those with high risk disease in a non-invasive manner. Prostate specific antigen (PSA) is used for clinical follow-up of prostate cancer; however, it is not effective as a screening tool. As a result, many men with non-life threatening disease having to undergo unnecessary and painful biopsies. Therefore, there is a dire need for minimally invasive platforms for monitoring patients with clinically significant prostate cancer. Prostate cell microparticles (PCMPs) released by prostate epithelial cells into plasma are a potential source of biomarkers specific for prostate …
Biomarkers Of Sepsis: A Retrospective Approach, Jose M. Roberts
Biomarkers Of Sepsis: A Retrospective Approach, Jose M. Roberts
Williams Honors College, Honors Research Projects
Background: Biomarkers are taking the spotlight in becoming the norm for early diagnoses. Sepsis is an inflammatory disease that increases metabolic rate in children. The first biomarker is hyponatremia. Hyponatremia is a frequent electrolyte imbalance in clinical practice, often observed in children with inflammatory disease and infection. Presence of hyponatremia is associated with electrical signaling imbalances, inflammation and renal dysfunction. The clinical value of hyponatremia in pediatric patients is unknown. The C-reactive protein is a second biomarker. Its presence signifies that necrotic cells and inflammation are present.
Objectives: To evaluate the use of biomarkers in children seen in the Emergency …