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Management Of Adult Growth Hormone Deficiency Related To Hypopituitarism, Kellie Jamin Jan 2022

Management Of Adult Growth Hormone Deficiency Related To Hypopituitarism, Kellie Jamin

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The treatment of growth hormone deficiency (GHD) is well-established in childhood but less understood in adults, given the more complex role that growth hormone (GH) assumes in this population. Decreased functionality of the pituitary gland, otherwise known as hypopituitarism, can present with an isolated GHD in adulthood, which may result from a number of factors including neoplasm, ischemia, infection, traumatic injury, or systemic disease. Adult GHD may be definitively diagnosed with a stimulation test, the insulin tolerance test (ITT) being the study of choice. With a positive ITT, the disorder can be treated with growth hormone replacement therapy (GHRT), which …


The Efficacy Of Mirnas As A Diagnostic Tool For Endometriosis, Maura Franey Jan 2021

The Efficacy Of Mirnas As A Diagnostic Tool For Endometriosis, Maura Franey

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Abstract

Introduction: Endometriosis is a chronic inflammatory gynecological condition. Laparoscopic abdominopelvic exploration is the gold standard of diagnosis, but is not performed until patients experience severe symptoms. This review analyzes the levels of circulating micro-RNAs (miRNAs) (I) for diagnosis of endometriosis (O) in women diagnosed with endometriosis (P) compared to laparoscopic exploration (C).

Methods: A literature search was conducted through PubMed and Cochrane Library in November 2019. A total of nine articles consisting of case-control or systematic reviews were selected based on publication date, main outcome, and the use of miRNAs or laparoscopy for diagnosis of endometriosis.

Results: The eight …


Oral Contraceptives As Possible Acl Injury Prevention Method, Haley Schweizer Jan 2020

Oral Contraceptives As Possible Acl Injury Prevention Method, Haley Schweizer

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ABSTRACT

Introduction: Anterior Cruciate Ligament (ACL) injuries are an upsetting setback for many athletes that require a long and costly recovery process. The injury rates are four times greater in women than men. Preventative measures that help to prevent ACL injuries are limited to stretching and strengthening. Therefore, this review aims to investigate if oral contraceptive [I] usage provides a possible new avenue for prevention of ACL injury [O] in young female athletes (ages 18-30) [P] compared to those that do not take oral contraceptives [C].

Methods: A literature review was performed though PubMed, Google Scholar, SCOPUS Database, and ClinicalKey …