Alternative and Complementary Medicine Commons^™

Perawatan Stroke Ampuh, Denature Terkini

deNature terkini

The Alternative Appeal, Courtney Deroo

Health Policy & Management Student Scholarship

For decades, Americans expressed dissatisfaction with conventional cancer treatments. I examine the appeal of biological alternatives to surgery, chemotherapy, and radiation therapy for patients with cancer. The limited effectiveness and side effects of many conventional cancer therapies led many patients to pursue a variety of unconventional therapies. To improve the quality of care for cancer patients, "mainstream" providers must better understand, and even collaborate with, alternative practitioners.

Identification Of Novel Molecular Targets Of Resveratrol In Colorectal Carcinogenesis, Nichelle Chantil Whitlock

Doctoral Dissertations

Current research suggests resveratrol, a phytoalexin found predominately in grapes, may function as a chemopreventive and/or chemotherapeutic agent for various cancers, including colorectal cancer. However, the underlying mechanism(s) involved in these activities remain elusive. Thus, the objective of the studies discussed here sought to investigate the effect of resveratrol treatment on gene modulation in human colorectal cancer cells in order to identify and characterize novel molecular targets that contribute to the observed anticancer activities of resveratrol. Here, we identify activating transcription factor 3 (ATF3) and early growth response-1 (Egr-1) as novel targets of resveratrol and provide data to elucidate the …

Editorial, Alok Kumar

Indian Journal of Research in Homoeopathy

No abstract provided.

An Exploratory Study On Scientific Investigations In Homeopathy Using Medical Analyzer, Nirupama Mishra, K Muraleedharan, Akalpita Paranjpe, Devendra Munta, Hari Singh, Chaturbhuja Nayak

Indian Journal of Research in Homoeopathy

Background: The action of homeopathic medicines, in ultra-high dilution, is not directly observable. An attempt was made to explore autonomic response of selective homeopathic medicines, in healthy persons, using Medical Analyzer System (Electronics Division, Bhabha Atomic Research Centre, Mumbai, India). Objective: The objective of the study was to observe the action of homeopathic medicines on physiologic variability of heart rate and blood flow. Material and methods: Pre- and postinterventional variability spectra of heart rate and blood flow of 77 subjects were recorded with the Medical Analyzer System, administering homeopathic preparations of Aconitum napellus (6c, 10M), Arsenicum album (200c, 1M), Gelsemium …

Evaluation Of Anti-Leukemic Activity Of Potentised Catharanthus Roseus: An In-Vitro Study, R Kushwaha, U Nagargoje

Indian Journal of Research in Homoeopathy

Alcoholic extract of potentised Catharanthus roseus (L.) G. Don. was evaluated for its anti-leukemic activity in in-vitro model. For this in- vitro study two cell lines namely, jurkat and K562 for promyelocytic leukemia and chronic myeloid leukemia were used. The cell lines were grown in Roswell Park Memorial Institute Medium (RPMI 1640 medium) containing 10% fetal bovine serum and 2mM L-glutamine. Doxorubicin (Adriamycin, ADR) was used as positive control drug. Growth inhibition of 50 % (GI50) was calculated from [(test growth in the presence of drug at the four concentration levels Ti - time zero Tz)/( control growth C-Tz)] x …

Pharmacognostic And Physico-Chemical Evaluation Of Lactuca Sativa L., P Subramanian, P Rao, P Reddy, H Gupta

Indian Journal of Research in Homoeopathy

Lactuca sativa L. is an erect, annual herb belonging to the family Asteraceae. The leaves are useful in angina pectoris, ascitis, asthma, constipation, cough, diarrhea, hysteria, gonorrhoea, affections of liver and spleen and pain in pylorus and spinal cord. Leaves are long, thin, orbicular or oblong, obovate, crisp and radical. The trichomes are uniseriate filiform capitate, uniseriate macroform conical and biseriate filiform capitate types; mesophyll is undifferentiated; laticiferous ducts and prismatic crystals are present in ground tissue; midvein bundle is bicollateral. The powder microscopic and organoleptic characters are provided. Physico-chemical parameters of raw drug viz., extractive values, ash values, formulation, …

Bacopa Monnieri - A Multicentric, Randomized, Double-Blind Homoeopathic Pathogenetic Trial, Rajpal Rajpal, Vinay Singh, V Siddiqui, C Nayak, P Mal, D Sarkar

Indian Journal of Research in Homoeopathy

Objective: To elicit the pathogenetic response of the drug Bacopa monnieri in homoeopathic potencies on healthy human beings. Methodology: Drug Bacopa monnieri was proved by the Central Council for Research in Homoeopathy through randomized, double-blind, placebo-controlled method. The study was conducted at two centers. The drug was proved in three potencies (6C, 30C and 200C) on 32 apparently healthy volunteers who were selected after conducting pre-trial medical examination by the medical specialists and routine laboratory investigations. In the first phase volunteers were given 56 doses (04 doses per day for 14 days) of placebo. In the next three phases 56 …

Homoeopathic Materia Medica Of Indian Drugs, L Nanda

Indian Journal of Research in Homoeopathy

No abstract provided.

A Case Of Multiple Urinary Calculi Treated With Homoeopathy, P Sumithran

Indian Journal of Research in Homoeopathy

A case of multiple urinary calculi, with size varying from five to seven millimeters in the left kidney and four to six millimeters in the right kidney, a thirteen millimeter stone in the left lower part of the ureter and a 20 x 13 millimeter stone in the base of the urinary bladder presenting complaints of burning micturition and pain in the lumbar region reported at the O.P.D of the Central Research Institute for Homoeopathy at Kottayam, Kerala. Patient was having urolithiasis complaints since four years and had undergone both allopathic and ayurvedic treatment, but the response was not satisfactory. …

Interview With Bertha Skaggs (Fa 593), Manuscripts & Folklife Archives

FA Oral Histories

Transcription of an interview with Bertha Skaggs conducted by Rachel Parsley for a folk studies class at Western Kentucky University. The interview revolves around the practice of folk medicine in the region around Mammoth Cave National Park, particularly Edmonson County, Kentucky.

Interview With Andrew Parsley (Fa 593), Manuscripts & Folklife Archives

FA Oral Histories

Transcription of an interview with Andrew Parsley conducted by his daughter Rachel Parsley for a folk studies class at Western Kentucky University. The content of the interview revolves around folk medicine as practiced in the region around Mammoth Cave National Park, particularly Edmonson County, Kentucky.

Supplemental Fish Oil Decreases Urinary Excretion Of A Marker Of Bone Resorption In Healthy Adults, Eric E. Noreen, Josef Brandauer, Megan H. Macnabb

Health Sciences Faculty Publications

Background: Incorporation of fish oil (FO) into the diet of rodents has been shown to result in positive changes in bone health. Currently it is poorly understood if FO has the same effects on bone health in humans. The purpose of this study was to determine the effects of supplemental FO on levels of urinary N-terminal cross-linked telopeptide (NTx), which is a marker of bone breakdown, and how this is related to the morning levels of salivary cortisol and urinary excretion of interleukin 6 (IL-6).

Methods: A total of twenty-eight females and twelve males(35 ± 13yrs; 69.1 ± 14.1kg; 29.4 …

Integrative Health Studies Newsletter, Ciis

Integrative Health Studies Newsletter

This is the Fall 2011 issue of the Integrative Health Studies Newsletter at CIIS.

We Are… Bridging Medicine And Science Vol. 1, Issue 1, Fall 2011, Marshall University Biomedical Sciences

We Are... Bridging Medicine Science

No abstract provided.

Reduced Cardioprotective Action Of Adiponectin In High-Fat Diet-Induced Type Ii Diabetic Mice And Its Underlying Mechanisms., Wei Yi, Yang Sun, Erhe Gao, Xufeng Wei, Wayne Bond Lau, Qijun Zheng, Yajing Wang, Yuexing Yuan, Xiaoliang Wang, Ling Tao, Rong Li, Walter Koch, Xin-Liang Ma

Department of Emergency Medicine Faculty Papers

Diabetes exacerbates ischemic heart disease morbidity and mortality via incompletely understood mechanisms. Although adiponectin (APN) reduces myocardial ischemia/reperfusion (MI/R) injury in nondiabetic animals, whether APN's cardioprotective actions are altered in diabetes, a pathologic condition with endogenously reduced APN, has never been investigated. High-fat diet (HD)-induced diabetic mice and normal diet (ND) controls were subjected to MI via coronary artery ligation, and given vehicle or APN globular domain (gAPN, 2 μg/g) 10 min before reperfusion. Compared to ND mice (where gAPN exerted pronounced cardioprotection), HD mice manifested greater MI/R injury, and a tripled gAPN dose was requisite to achieve cardioprotective extent …

Systemic Adiponectin Malfunction As A Risk Factor For Cardiovascular Disease., Wayne Bond Lau, Ling Tao, Yajing Wang, Rong Li, Xin L Ma

Department of Emergency Medicine Faculty Papers

Adiponectin (Ad) is an abundant protein hormone regulatory of numerous metabolic processes. The 30 kDa protein originates from adipose tissue, with full-length and globular domain circulatory forms. A collagenous domain within Ad leads to spontaneous self-assemblage into various oligomeric isoforms, including trimers, hexamers, and high-molecular-weight multimers. Two membrane-spanning receptors for Ad have been identified, with differing concentration distribution in various body tissues. The major intracellular pathway activated by Ad includes phosphorylation of AMP-activated protein kinase, which is responsible for many of Ad's metabolic regulatory, anti-inflammatory, vascular protective, and anti-ischemic properties. Additionally, several AMP-activated protein kinase-independent mechanisms responsible for Ad's anti-inflammatory …

Advanced Glycation End Products Accelerate Ischemia/Reperfusion Injury Through Receptor Of Advanced End Product/Nitrative Thioredoxin Inactivation In Cardiac Microvascular Endothelial Cells., Yi Liu, Yanzhuo Ma, Rutao Wang, Chenhai Xia, Rongqing Zhang, Kun Lian, Ronghua Luan, Lu Sun, Lu Yang, Wayne B Lau, Haichang Wang, Ling Tao

Department of Emergency Medicine Faculty Papers

The advanced glycation end products (AGEs) are associated with increased cardiac endothelial injury. However, no causative link has been established between increased AGEs and enhanced endothelial injury after ischemia/reperfusion. More importantly, the molecular mechanisms by which AGEs may increase endothelial injury remain unknown. Adult rat cardiac microvascular endothelial cells (CMECs) were isolated and incubated with AGE-modified bovine serum albumin (BSA) or BSA. After AGE-BSA or BSA preculture, CMECs were subjected to simulated ischemia (SI)/reperfusion (R). AGE-BSA increased SI/R injury as evidenced by enhanced lactate dehydrogenase release and caspase-3 activity. Moreover, AGE-BSA significantly increased SI/R-induced oxidative/nitrative stress in CMECs (as measured …

Doulas Going Dutch: The Role Of Professional Labor Support In The Netherlands, Monica He

Independent Study Project (ISP) Collection

This study uses a mixed method approach and medicalization theory to explore the new role of professional doulas in the Netherlands through the perspectives of women who have had doula-attended births. Survey data from the Dutch doula association is first analyzed in order to quantify women’s experiences with doula care and characterize their demographic information and birth outcomes. Simulatenously, nine in-depth interviews are conducted with Dutch and non- Dutch mothers who have recently had doula-attended births. The interviews focus on experiences with doula care in the context of the Dutch maternity care system. Quantitative analysis finds women who had doulas …

La Medicina Tradicional Y La Medicina Moderna En Cusco, Katelyn Scott

Independent Study Project (ISP) Collection

Cuando estaba tratando a escoger un tema para esta investigación encontré esta cita, “In the assessment of the World Health Organization (WHO), the majority of the population of most developing countries regularly use and rely on traditional medicine for their everyday healthcare needs[1]” (Bodeker 23). En hecho, WHO dice que casi 80% de la población de un país desarrollado todavía usa la medicina tradicional (Mendoza, 439). Estas citas me interesé y por eso decidí a investigar las perspectivas que las personas en Cusco tienen sobre la medicina tradicional y la medicina moderna. Quiera aprender si la medicina tradicional …

Syllabus "Externship: Mindfulness Meditation Retreat At Starved Rock State Park", Michael Skelley

Michael Skelley, Ph.D.

No abstract provided.

Standardisation Of Homoeopathic Drug - Syzygium Jambos (L.) Alston, P Rao, P Subramanian, P Reddy, H Gupta

Indian Journal of Research in Homoeopathy

Syzygium jambos, a small tree belonging to the family Myrtaceae is a potential drug in Homoeopathy. The drug is useful in clinical conditions like acne, pimples, nausea, comedones, headache, heartburn, abdominal colic, diarrhoea and fever. The seeds are up to 2.5 cm long, ellipsoid to oblong, narrowed at middle. Seed coat is rough, thick, sclerotic and papery, made of tangentially elongated lignified cells with dense contents and separating from the endosperm. Cortex is 20 - 40 layered, interspersed with groups of sclerenchyma fibers. The endosperm possess large secretory cavities in the hypodermal areas. The endosperm is filled with starch grains …

Editorial, Alok Kumar

Indian Journal of Research in Homoeopathy

No abstract provided.

Germination And Vigor Of Lettuce Seeds (Lactuca Sativa L.) Pelleted With Homoeopathic Preparations Alumina And Calcarea Carbonica Subjected To Toxic Levels Of Aluminum, Filipe Bonfim, Rosana Rodrigues Das Dores, Ernane Martins, Vicente Dias Casali

Indian Journal of Research in Homoeopathy

Background: Aluminum toxicity is the most important factor limiting the growth of plants in acid soils, whereas current treatments are unfeasible. For this reason, alternatives are sought for, among which homoeopathic treatment. Aims: This study aimed at evaluating the influence of homoeopathic preparations Alumina 6cH, Alumina 12cH, Calcarea carbonica 6cH and Calcarea carbonica 12cH on the germination and vigor of lettuce seeds subjected to toxic levels of aluminum in paper-solution. At the same time, it was sought to develop a new procedure to apply homoeopathic preparations in plants (pelleting). Methods: The statistical design was entirely randomized (CRD) with 6 treatments …

Asclepias Currasavica- A Multicentric, Randomized, Double-Blind Homoeopathic Pathogenetic Trial, Rajpal Rajpal, Vinay Singh, V Siddiqui, C Nayak, A Majunder, D Sardar, P Sivadas, K Banoth

Indian Journal of Research in Homoeopathy

Objective: To elicit the pathogenetic response of the drug Asclepias currasavica in homoeopathic potencies on healthy human beings. Methodology: Drug Asclepias currasavica was proved by the Central Council for Research in Homoeopathy through randomized, double-blind, placebo-controlled method. The study was conducted at four centers. The drug was proved in two potencies (6C and 30C) on 67 apparently healthy volunteers who were selected after conducting pre-trial medical examination by the medical specialists and routine laboratory investigations. In the first phase volunteers were given 56 doses (04 doses per day for 14 days) of placebo. In the next two phases 56 doses …

Neuroprotective Effect Of Bellis Perennis And Hypericum Perforatum On Pc12 Cells, Andleeb Khan, Kumar Vaibhav, Hayate Javed, Mohd Khan, Rizwana Tabassum, Md Ahmed, Syed Raza, Mohd Ashafaq, V Khuwaja

Indian Journal of Research in Homoeopathy

The rat pheochromocytoma (PC12) cell line is widely applied as a model system to study a variety of neuronal functions. Upon addition of nerve growth factor (NGF), these cells undergo differentiation characterized by an increase in acetylcholinesterase (AChE) activity, and extension of neurite-like processes. Oxidative stress is implicated in the pathogenesis of neurodegenerative disorders and the purpose of this study was to evaluate the effect of Bellis perennis (Be) and Hypericum perforatum (Hy) (6C and 30C) on healthy neuronal cells. Both homeopathic medicines have been studied at three different concentrations of 2 μl/ml, 4 μl/ml and 8 μl/ml for 96 …

Alfalfa - A Multicentric Clinical Verification Study, P Chakraborty, Subhash Kaushik, S Nain, Pramodji Singh, V Prasad, Darshan Singh, K Das, Ojit Singh, Gulrana Pradhan

Indian Journal of Research in Homoeopathy

Introduction: Clinical verification programme is an ongoing research programme of the Central Council for Research in Homoeopathy since its inception, under which many Indian and rarely used drugs in Homoeopathy have been undertaken. Alfalfa is a flowering plant and known for its use as a medicine in toning up the appetite and digestion and favorably influencing nutrition. Disorders like anorexia, nervousness, insomnia, diabetes, lethargy and malnutrition are mainly within its therapeutic range. The Council had undertaken an observational study on Alfalfa from October 2005 to March 2010, to determine its therapeutic effect through clinical verification. Objectives: The primary objective was …

Study Of Homoeopathic Medicines Through Clinical Verification-A New Perspective (Volume-I & Ii), V Gupta

Indian Journal of Research in Homoeopathy

No abstract provided.

A Prospective Multicentre Observational Study To Evolve The Usefulness Of Group Of Homoeopathic Medicines In The Management Of Acute Tracheobronchitis, C Nayak, V Singh, H Singh, V Siddiqui, J Gupta, A Mishra, M Padmanabhan, S Sharma, Prasad

Indian Journal of Research in Homoeopathy

Abstract : Sn open multicentre clinical trial was aimed to evolve the usefulness of a group of homoeopathic medicines in the management of acute tracheobronchitis with regard to improvement in its symptom complex. Patients presenting coryza with irritable dry or productive cough, oppression chest and neutrophillic leucocytosis were enrolled in the study from October 2005 to September 2008. Severity of patients′ disease condition was evaluated as per tracheobronchitis symptom scale. Symptoms of disease as well as characteristic symptoms of individual patients were considered for selection of medicine from a group of 14 trial medicines. Selected medicine was prescribed in 6C …

The Growth Suppressing Effects Of Girinimbine On Hepg2 Involve Induction Of Apoptosis And Cell Cycle Arrest, Syam Mohan

Syam Mohan

Murraya koenigii is an edible herb widely used in folk medicine. Here we report that girinimbine, a carbazole alkaloid isolated from this plant, inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells. The MTT and LDH assay results showed that girinimbine decreased cell viability and increased cytotoxicity in a dose-and time-dependent manner selectively. Girinimbine-treated HepG2 cells showed typical morphological features of apoptosis, as observed from normal inverted microscopy and Hoechst 33342 assay. Furthermore, girinimbine treatment resulted in DNA fragmentation and elevated levels of caspase-3 in HepG2 cells. Girinimbine treatment also displayed a time-dependent accumulation of the Sub-G(0)/G(1) …