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Articles 121 - 150 of 1872

Full-Text Articles in Medicine and Health Sciences

The Correlation Between The Season Of Birth And Early Child Development In Healthy Children: Evidence From The Midwestern Region Of The United States: A Pilot Study, Elizabeth G. Bodensteiner Jan 2023

The Correlation Between The Season Of Birth And Early Child Development In Healthy Children: Evidence From The Midwestern Region Of The United States: A Pilot Study, Elizabeth G. Bodensteiner

Physical Therapy Scholarly Projects

Background and Purpose: Research has been conducted in countries like Japan and China assessing the impact of various factors on gross motor development. One variable that has been researched and discussed within studies in other countries is the relationship between gross motor development and birth season. This study aimed to address the impact of birth season on gross motor development, specifically within the Midwestern region of the United States. There is limited research regarding this topic within the Midwestern region of the United States.

Materials and Methods: Parents of 114 children completed self-reports on their children’s gross and …


Different Age Groups Present Different Clinics In Anaphylaxis With Children: One Size Does Not Fit All Children, Nevzat Başkaya, Ayşegül Ertuğrul, Sali̇ha Esenboğa, Serap Özmen Jan 2023

Different Age Groups Present Different Clinics In Anaphylaxis With Children: One Size Does Not Fit All Children, Nevzat Başkaya, Ayşegül Ertuğrul, Sali̇ha Esenboğa, Serap Özmen

Turkish Journal of Medical Sciences

Background/aim: Childhood anaphylaxis presents with a heterogeneous clinic. Elicitors and epidemiologic factors associated with anaphylaxis differ with age, geographic location and lifestyle. This study aimed to determine the clinical features and age-specific patterns of childhood anaphylaxis in a single referral center in Turkey. Materials and methods: We conducted a retrospective study of anaphylaxis in children aged between 0 and 18 years of age, attending an allergy department in a children's hospital. Results: A total of 95 children diagnosed with anaphylaxis were analyzed. Among all, 35.8% of the first anaphylaxis episodes occurred in infancy and 57.9% in preschool age. Foods were …


A Prospective Study For An Alternative Probe Site For Pulse Oximetry Measurement In Male Patients With Severe Burn Trauma: Penile Shaft, Yeşi̇m Andiran Şenayli, Gülsen Keski̇n, Mi̇ne Akin, Ati̇lla Şenayli, Rabi̇a Ata, Gökhan Demi̇rtaş, Emrah Şenel Jan 2023

A Prospective Study For An Alternative Probe Site For Pulse Oximetry Measurement In Male Patients With Severe Burn Trauma: Penile Shaft, Yeşi̇m Andiran Şenayli, Gülsen Keski̇n, Mi̇ne Akin, Ati̇lla Şenayli, Rabi̇a Ata, Gökhan Demi̇rtaş, Emrah Şenel

Turkish Journal of Medical Sciences

Background/aim: Authors widely use pulse oximetry in clinical monitoring of heart rate (HR) and peripheral oxygen saturation (SpO2) by attachment to the fingers; however, there can be a need for an alternative attachment site, especially for burned patients. We investigate the availability of a pulse oximeter probe attached to the penile shaft as an alternative site in pediatric male patients if all extremities became unavailable for pulse oximetry measurement due to severe burn and/or trauma. Materials and methods: We designed a prospective comparative study in a training and research hospital. After local ethical committee approval, pediatric male cases eligible for …


Turkish Validity And Reliability Of The Level Of Sitting Scale In Children With Cerebral Palsy, Kami̇le Uzun Akkaya, Sabi̇ha Bezgi̇n, Debra Field, Bülent Elbasan Jan 2023

Turkish Validity And Reliability Of The Level Of Sitting Scale In Children With Cerebral Palsy, Kami̇le Uzun Akkaya, Sabi̇ha Bezgi̇n, Debra Field, Bülent Elbasan

Turkish Journal of Medical Sciences

Background/aim: The Level of Sitting Scale (LSS) is a valid and reliable classification index that categorizes sitting ability. The aim of this study is to establish the Turkish validity and reliability of the LSS in children with cerebral palsy (CP). Materials and methods: In total, 165 children (75 girls and 90 boys) between the ages of 4 and 18 years who were diagnosed with CP were included in the study. All children were evaluated by two independent physiotherapists for the interrater reliability analysis of the LSS and were reevaluated 1 week later by the same physiotherapist for the intrarater reliability …


Clinical Characteristics And Outcomes Of Continuous Renal Replacement Therapy Performed On Younger Children Weighing Up To 10 Kg, Emrah Gün, Anar Gurbanov, Özlem Saritaş Naki̇p, Ahmet Yöntem, Ayşen Durak Aslan, Edi̇n Botan, Fevzi̇ Kahveci̇, Serhan Özcan, Ebru Azapağasi, Serhat Emeksi̇z, Mutlu Uysal Yazici, Selman Kesi̇ci̇, Özden Özgür Horoz, Ömer Erdeve, Benan Bayrakci̇ Jan 2023

Clinical Characteristics And Outcomes Of Continuous Renal Replacement Therapy Performed On Younger Children Weighing Up To 10 Kg, Emrah Gün, Anar Gurbanov, Özlem Saritaş Naki̇p, Ahmet Yöntem, Ayşen Durak Aslan, Edi̇n Botan, Fevzi̇ Kahveci̇, Serhan Özcan, Ebru Azapağasi, Serhat Emeksi̇z, Mutlu Uysal Yazici, Selman Kesi̇ci̇, Özden Özgür Horoz, Ömer Erdeve, Benan Bayrakci̇

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the clinical features, modality, complications, and effecting factors on the survival of children weighing up to 10 kg who received continuous renal replacement therapy (CRRT). Materials and methods: This study was a retrospective observational study conducted in five pediatric intensive care units in tertiary hospitals in Turkey between January 2015 and December 2019. Results: One hundred and forty-one children who underwent CRRT were enrolled in the study. The median age was 6 (range, 2-12) months, and 74 (52.5%) were male. The median weight of the patients was 6 (range, 4-8.35) kg and 52 (36.9%) …


Effectiveness Of The Catch (Coordinated Approach To Child’S Health) Rainbow Program In Elementary Schools For Change In Fruit And Vegetable Intake, Ashley M. Valinskas Jan 2023

Effectiveness Of The Catch (Coordinated Approach To Child’S Health) Rainbow Program In Elementary Schools For Change In Fruit And Vegetable Intake, Ashley M. Valinskas

Graduate Research Theses & Dissertations

Background: There is currently a lack of nutrition education programs that effectively increase fruit and vegetable (FV) intake among children. Not meeting the recommendations for fruits and vegetables increases the risk for poor academic achievement, obesity, and chronic diseases such as cardiovascular disease, type II diabetes, asthma, and more. Nutrition, cooking, and gardening lessons individually and together have shown to increase fruit and vegetable (FV) consumption in school-aged children.Methods: Two-Hundred Twenty-five 4th and 5th graders participated in six cooking and six gardening lessons between September 2021 and May 2022 at Genoa Elementary school. Each nutrition education session was 25-minutes long, …


The Experiences Of Parents Diagnosed With Cancer Whilst Parenting Minor-Aged Children, George Prince Jan 2023

The Experiences Of Parents Diagnosed With Cancer Whilst Parenting Minor-Aged Children, George Prince

Theses

The incidence of cancer in Australia for people in the parenting age range is significant, and as the fertility rate of women aged 35 years and over continues to rise, many cancer patients may be parenting minor-aged children. The aim of this research was therefore to explore the lived experience of parents diagnosed with cancer whilst parenting minor-aged children, and to gain knowledge and understanding as to how parents and their families respond to a parent’s cancer illness. Utilising a qualitative research design, eight participants, receiving treatment for cancer in a private hospital cancer treatment service, and parenting at least …


Effectiveness Of Speech Intervention Methods In Children With Speech Delays, Andrea Noel, Rachel Windemuth, Brett Porter Jan 2023

Effectiveness Of Speech Intervention Methods In Children With Speech Delays, Andrea Noel, Rachel Windemuth, Brett Porter

Williams Honors College, Honors Research Projects

Speech delays in children is a common issue that can be treated by a wide variety of interventions. Our PICOT question is, in children, ages six months to thirteen years, with speech/language delays, how does the addition of innovative and supplemental interventions, compared with standard interventions alone, effect improvements in the delays. All three group members have known someone who has suffered from a speech delay, and we want to research the best possible methods to overcome that obstacle to answer our questions, we will begin to take on the task of creating and writing a systematic review. This review …


The Effect Of Start-Play Intervention On Reaching-Related Exploratory Behaviors In Children With Neuromotor Delays: A Secondary Analysis Of A Randomized Controlled Trial, Iryna Babik Jan 2023

The Effect Of Start-Play Intervention On Reaching-Related Exploratory Behaviors In Children With Neuromotor Delays: A Secondary Analysis Of A Randomized Controlled Trial, Iryna Babik

Psychological Sciences Faculty Publications and Presentations

Aims

Children with neuromotor delays are at risk for reaching and object exploration impairments, which may negatively affect their cognitive development and daily activity performance. This study evaluated the effectiveness of the Sitting Together And Reaching To Play (START-Play) intervention on reaching-related exploratory behaviors in children with neuromotor delays.

Methods

In this randomized controlled clinical trial, 112 children (Mean = 10.80, SD = 2.59 months old at baseline) with motor delays were randomly assigned to receive START-Play intervention or usual care-early intervention. Performance for ten reaching-related exploratory behaviors was assessed at baseline and 1.5, 3, 6, 12 months post-baseline. …


Changes In Parental Anxiety And Intention To Demand Antibiotics: A Longitudinal Study Among Parents During The Covid-19 Pandemic, Aaron L. Alejandro, Mieghan Bruce, Wei W. C. Leo Jan 2023

Changes In Parental Anxiety And Intention To Demand Antibiotics: A Longitudinal Study Among Parents During The Covid-19 Pandemic, Aaron L. Alejandro, Mieghan Bruce, Wei W. C. Leo

Research outputs 2022 to 2026

Aims: Assessing the effects of the COVID-19 pandemic on parental anxiety and preferences for antibiotic treatment can help inform antibiotic stewardship strategies. Therefore, this study aimed to examine COVID-19 pandemic-related changes in parental anxiety levels, their intentions to demand antibiotics and frequencies of practising preventative behaviours. Design: This longitudinal quantitative study compared two groups of parents, those from Victoria and Western Australia, who experienced high and low COVID-19 risk, respectively. Methods: Participants were recruited through an online panel to complete three waves of surveys between October 2020 and August 2021. Anxiety scores and frequency of preventative behaviours were analysed using …


Covid-19 In Western Australia: ‘The Last Straw’ And Hopes For A ‘New Normal’ For Parents Of Children With Long-Term Conditions, Stephanie Smith, Mary Tallon, James Smith, Lauren Jones, Evalotte Mörelius Jan 2023

Covid-19 In Western Australia: ‘The Last Straw’ And Hopes For A ‘New Normal’ For Parents Of Children With Long-Term Conditions, Stephanie Smith, Mary Tallon, James Smith, Lauren Jones, Evalotte Mörelius

Research outputs 2022 to 2026

Background: Children with long-term conditions are vulnerable due to the treatments required for their conditions. Since the start of the coronavirus disease 2019 (COVID-19) pandemic, Western Australians experienced restrictions that changed daily life activities but were able to return to some of their previous routines due to the restrictions. Aim: The study explored the stress experiences of parents caring for children with long-term conditions during COVID-19 in Western Australia. Design and Participants: The study was codesigned with a parent representative caring for children with long-term conditions to ensure essential questions were targeted. Twelve parents of children with various long-term conditions …


A Novel Skin Cancer Prevention Strategy: Preservice Teachers' Perceptions Of A Sun Safety Intervention And Experiences In Schools, Joseph J. Scott, Robyn S. Johnston, Jill Darby, Sally Blane, Mark Strickland, Bronwen M. Mcnoe Jan 2023

A Novel Skin Cancer Prevention Strategy: Preservice Teachers' Perceptions Of A Sun Safety Intervention And Experiences In Schools, Joseph J. Scott, Robyn S. Johnston, Jill Darby, Sally Blane, Mark Strickland, Bronwen M. Mcnoe

Research outputs 2022 to 2026

Issue addressed:

Teachers play a vital role in developing children's sun protection routines however upskilling preservice teachers (PSTs) while at university has not yet been trialled as a targeted skin cancer prevention strategy. Hence, this study investigated PSTs perceptions and experiences of sun safety following a brief pilot intervention and placement in primary schools in Western Australia.

Methods:

This study used a triangulation mixed methods design. Participants (n = 161) completed a post intervention survey which was analysed quantitatively. A random sub-sample was invited to participate in focus groups (three groups, n = 21) and one-on-one interviews (n = 4). …


The Natural History Of Symptomatic Fractures In Children And Adolescents With Osteogenesis Imperfecta Type 1: A Cohort Study From Western Australia, Kiranjit K. Joshi, Aris Siafarikas, Richard Prince Jan 2023

The Natural History Of Symptomatic Fractures In Children And Adolescents With Osteogenesis Imperfecta Type 1: A Cohort Study From Western Australia, Kiranjit K. Joshi, Aris Siafarikas, Richard Prince

Research outputs 2022 to 2026

The fracture experience of children and adolescents with osteogenesis imperfecta (OI) type 1 is not well described in the literature. We present data on symptomatic long bones and axial skeleton fractures of all patients aged 0 to 18 years with OI type 1 seen at a specialized bone clinic in Western Australia in the period 2008 to 2020 using a retrospective chart review method. The cohort consisted of 44 patients (21 males, 23 females). Median (interquartile range [IQR]) age was 11.3 (6.2 to 17) years, giving a total of 520 patient-years in the study during which 197 fractures were experienced. …


The Effects Of Screen Time On Children, Jacqueline Valdepenas Jan 2023

The Effects Of Screen Time On Children, Jacqueline Valdepenas

Nursing | Senior Theses

With the development of technology continuing to grow at a fast-paced pace in society, children are now becoming exposed to such technology at a younger age. The introduction of smartphones and tablets, which is defined as screen time in this paper, are being introduced to children as young as 6 months of age. Instead of children playing with toys recommended for their age, they use screen time for their play needs and entertainment. Some parents use screen time as a distraction and/or relief for their own needs when the child is upset or they’re unable to tend to the child. …


Acute Kidney Injury In Hospitalized Children With Sickle Cell Anemia, Anthony Batte, Sahit Menon, John Ssenkusu, Sarah Kiguli, Robert Kalyesubula, Joseph Lubega, Edrisa Ibrahim Mutebi, Robert Opoka, Chandy John, Michelle Starr Dec 2022

Acute Kidney Injury In Hospitalized Children With Sickle Cell Anemia, Anthony Batte, Sahit Menon, John Ssenkusu, Sarah Kiguli, Robert Kalyesubula, Joseph Lubega, Edrisa Ibrahim Mutebi, Robert Opoka, Chandy John, Michelle Starr

Paediatrics and Child Health, East Africa

Background: Children with sickle cell anemia (SCA) are at increased risk of acute kidney injury (AKI) that may lead to death or chronic kidney disease. This study evaluated AKI prevalence and risk factors in children with SCA hospitalized with a vaso-occlusive crisis (VOC) in a low-resource setting. Further, we evaluated whether modifcations to the Kidney Disease: Improving Global Outcomes (KDIGO) defnition would infuence clinical outcomes of AKI in children with SCA hospitalized with a VOC.

Methods: We prospectively enrolled 185 children from 2 – 18 years of age with SCA (Hemoglobin SS) hospitalized with a VOC at a tertiary hospital …


Blackwater Fever And Acute Kidney Injury In Children Hospitalized With An Acute Febrile Illness: Pathophysiology And Prognostic Significance, Andrea Conroy, Michael Hawkes, Aleksandra Leligdowicz, Ivan Mufumba, Michelle Starr, Kathleen Zhong, Sophie Namasopo, Robert Opoka, Chandy John, Kevin C. Kain Dec 2022

Blackwater Fever And Acute Kidney Injury In Children Hospitalized With An Acute Febrile Illness: Pathophysiology And Prognostic Significance, Andrea Conroy, Michael Hawkes, Aleksandra Leligdowicz, Ivan Mufumba, Michelle Starr, Kathleen Zhong, Sophie Namasopo, Robert Opoka, Chandy John, Kevin C. Kain

Paediatrics and Child Health, East Africa

Background: Acute kidney injury (AKI) and blackwater fever (BWF) are related but distinct renal complications of acute febrile illness in East Africa. The pathogenesis and prognostic signifcance of BWF and AKI are not well understood.

Methods: A prospective observational cohort study was conducted to evaluate the association between BWF and AKI in children hospitalized with an acute febrile illness. Secondary objectives were to examine the association of AKI and BWF with (i) host response biomarkers and (ii) mortality. AKI was defned using the Kidney Disease: Improving Global Outcomes criteria and BWF was based on parental report of tea-colored urine. Host …


Improving The Perioperative Experience Of Patients And Families In A Pediatric Setting, Anjanette Pong Dec 2022

Improving The Perioperative Experience Of Patients And Families In A Pediatric Setting, Anjanette Pong

Student Scholarly Projects

Practice Problem: The experience of surgery for pediatric patients and their families can be dependent on multiple factors including adequate preparation, English language proficiency and realistic expectations. Anxiety can contribute to a negative experience that may result in poor outcomes and a damaging reflection of the healthcare team and organization.

PICOT: The PICOT question that guided this project was: In preoperative pediatric patients and their families, how do therapeutic communication style and the provision of information about the perioperative experience affect their healthcare experience over eight weeks?

Evidence: A multi-modal approach to providing tailored preoperative education for the child and …


Safe Practices For Preventing Covid-19 Among School-Aged Children, Meleena Reyelle Banda-Garcia Dec 2022

Safe Practices For Preventing Covid-19 Among School-Aged Children, Meleena Reyelle Banda-Garcia

Nursing | Senior Theses

Communicable diseases and infections are common health problems among children. Among the most impactful communicable diseases present today is COVID-19, a disease caused by a virus named SARS-CoV-2, which has forced many school closures due to rapid transmission. Despite children not being the main driving factor of the spread of the disease, severe complications underlying COVID-19 incidence have resulted in increased hospitalization among school-age children.The initial global response to the spread of COVID-19 included the closure of school systems; however as the disease continues to be effectively managed, communities are starting to re-open schools partially or entirely nationwide. Although pharmaceutical …


Tip-Over Injuries Among Children: Data From An Urban Emergency Department Of Karachi, Pakistan, Rubaba Naeem, Asrar Ali, Ahmed Raheem Buksh, Ayesha Quddusi, Uzma Rahim Khan Nov 2022

Tip-Over Injuries Among Children: Data From An Urban Emergency Department Of Karachi, Pakistan, Rubaba Naeem, Asrar Ali, Ahmed Raheem Buksh, Ayesha Quddusi, Uzma Rahim Khan

Department of Emergency Medicine

Introduction: Most unintentional injuries among children occur in the home environment. Tip-overs, defined as incidents where heavy objects fall on children due to some type of interaction, are one of the reasons for injuries inside the home. This study aims to determine injury patterns and outcomes for child injuries resulting from tip-overs in the home environment as reported in the emergency department.
Methods: We performed a retrospective chart review of pediatric (under 18 years) tip-overs injuries occurred in years 2010 to 2015 at the Aga Khan University Hospital. Furthermore, parents of injured children participated in phone interviews to provide information …


Speech-Language Pathologists’ Treatment Goals For Preschool Language Disorders: An Icf Analysis, Elaine Yl Kwok, Peter Rosenbaum, Barbara Jane Cunningham Nov 2022

Speech-Language Pathologists’ Treatment Goals For Preschool Language Disorders: An Icf Analysis, Elaine Yl Kwok, Peter Rosenbaum, Barbara Jane Cunningham

PRECISe Preschool Speech and Language Publications

Purpose: The World Health Organization's International Classification of Functioning, Disability and Health (ICF) provides a comprehensive framework to conceptualise clinical services. This study explored how speech-language pathologists (SLPs) conceptualised therapy goals for preschoolers with language difficulties and disorders within the ICF framework.Method: An online survey was distributed to SLPs practising in a publicly funded Preschool Speech and Language program in Ontario, Canada. SLPs rated their familiarity with the ICF framework, and then reported all therapy goals for one child with language difficulty/disorder on their caseload. For each reported goal, SLPs indicated the ICF component(s) they felt the …


The Role Of Metformin In Treatment Of Weight Gain Associated With Atypical Antipsychotic Treatment In Children And Adolescents: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Zeeshan Mansuri, Ramkrishna Makani, Chintan Trivedi, Mahwish Adnan, Ramu Vadukapuram, John Rafael, Ashutosh Lodhi, Abhishek Reddy Nov 2022

The Role Of Metformin In Treatment Of Weight Gain Associated With Atypical Antipsychotic Treatment In Children And Adolescents: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Zeeshan Mansuri, Ramkrishna Makani, Chintan Trivedi, Mahwish Adnan, Ramu Vadukapuram, John Rafael, Ashutosh Lodhi, Abhishek Reddy

School of Medicine Publications and Presentations

Introduction: Second-generation antipsychotics are associated with significant weight gain. The aim of this systematic review and meta-analysis was to determine the efficacy and safety of metformin for the treatment of weight gain in children and young adults treated with second-generation antipsychotics.

Methods: We followed PRISMA guidelines to evaluated studies published before March 2020 in Medline, Google Scholar, PubMed, Cochrane library database, annual scientific sessions of the American Psychiatric Association, American Academy of Child and Adolescent, Psychiatry, and American Society of Clinical Psychopharmacology. Studies included compared metformin with the placebo for management of weight gain in children and adolescents taking atypical …


Functional Links Between Thermoregulation And Sleep In Children With Neurodevelopmental And Chronic Health Conditions, Susan M. Mccabe, Chris R. Abbiss, Jean Pierre Libert, Véronique Bach Nov 2022

Functional Links Between Thermoregulation And Sleep In Children With Neurodevelopmental And Chronic Health Conditions, Susan M. Mccabe, Chris R. Abbiss, Jean Pierre Libert, Véronique Bach

Research outputs 2022 to 2026

The bi-directional relationship between sleep and wake is recognized as important for all children. It is particularly consequential for children who have neurodevelopmental disorders (NDDs) or health conditions which challenge their sleep and biological rhythms, and their ability to maintain rhythms of participation in everyday activities. There are many studies which report the diverse reasons for disruption to sleep in these populations. Predominantly, there is focus on respiratory, pharmaceutical, and behavioral approaches to management. There is, however, little exploration and explanation of the important effects of body thermoregulation on children’s sleep-wake patterns, and associated behaviors. Circadian patterns of sleep-wake are …


Mothers’ Satisfaction With Distraction As A Postoperative Pain Management Intervention For Their Child: An Interventional Study, Edlin Glane Mathias, Mamatha Shivananda Pai, Vijay Kumar, Vasudeva Guddattu, Ann-Cathrine Bramhagen Nov 2022

Mothers’ Satisfaction With Distraction As A Postoperative Pain Management Intervention For Their Child: An Interventional Study, Edlin Glane Mathias, Mamatha Shivananda Pai, Vijay Kumar, Vasudeva Guddattu, Ann-Cathrine Bramhagen

Journal of Perioperative Nursing

Aim: This study aimed to investigate mothers’ levels of satisfaction with distraction as a post-operative pain management intervention for their child.

Background: Although the number of studies on paediatric pain management has increased over time, research into non-pharmacological post-operative pain management remains inadequate, indicating that more research is required.

Design: A posttest-only control group design was adopted to measure mothers’ levels of satisfaction with distraction as a non-pharmacological post-operative pain management intervention for their child.

Methods: The study included 160 mothers and their children undergoing elective surgery in a paediatric surgical unit. Mothers and children were randomly allocated to intervention …


The Enigma Of Primary Hypertension In Childhood, Bonita Falkner Nov 2022

The Enigma Of Primary Hypertension In Childhood, Bonita Falkner

Department of Medicine Faculty Papers

Beginning in the 1970s, hypertension in children and adolescents has been defined as systolic and/or diastolic blood pressure (BP) that is equal to or greater than the 95th percentile of the normal BP distribution in healthy children. The definition of hypertension in adults is based on longitudinal data that links a BP level with an increased risk for subsequent adverse outcomes related to hypertension including heart failure, kidney failure, stroke, or death. The statistical definition of hypertension continues to be used in childhood because there have been no data that link a BP level in childhood with a heightened risk …


The Childhood Acute Illness And Nutrition (Chain) Network Nested Case-Cohort Study Protocol: A Multi-Omics Approach To Understanding Mortality Among Children In Sub-Saharan Africa And South Asia, James M. Njunge, Kirkby Tickell, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahi, Md Amran Gazi, Ali Faisal Saleem, Zaubina Kazi, Syed Ali, Caroline Tigoi, Ezekiel Mupere Nov 2022

The Childhood Acute Illness And Nutrition (Chain) Network Nested Case-Cohort Study Protocol: A Multi-Omics Approach To Understanding Mortality Among Children In Sub-Saharan Africa And South Asia, James M. Njunge, Kirkby Tickell, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahi, Md Amran Gazi, Ali Faisal Saleem, Zaubina Kazi, Syed Ali, Caroline Tigoi, Ezekiel Mupere

Department of Paediatrics and Child Health

Introduction: Many acutely ill children in low- and middle-income settings have a high risk of mortality both during and after hospitalisation despite guideline-based care. Understanding the biological mechanisms underpinning mortality may suggest optimal pathways to target for interventions to further reduce mortality. The Childhood Acute Illness and Nutrition (CHAIN) Network ( www.chainnnetwork.org) Nested Case-Cohort Study (CNCC) aims to investigate biological mechanisms leading to inpatient and post-discharge mortality through an integrated multi-omic approach.
Methods and analysis; The CNCC comprises a subset of participants from the CHAIN cohort (1278/3101 hospitalised participants, including 350 children who died and 658 survivors, and …


Prevalence Of Hiv And Associated Risk Factors Among Street-Connected Children In Mwanza City, Said Nyumayo, Eveline Konje, Benson Kidenya, Anthony Kapesa, Marko Hingi, Nyagwegwe Wango, Joshua Ngimbwa, Violeth Alphonce, Namanya Basinda Nov 2022

Prevalence Of Hiv And Associated Risk Factors Among Street-Connected Children In Mwanza City, Said Nyumayo, Eveline Konje, Benson Kidenya, Anthony Kapesa, Marko Hingi, Nyagwegwe Wango, Joshua Ngimbwa, Violeth Alphonce, Namanya Basinda

Institute for Educational Development, East Africa

While on the street, HIV infection among street-connected children is a challenging issue due to the nature of transmission, distribution, and prevention. Lack of proper care and protection, insufficient knowledge of the danger of acquiring HIV, and insufficient or absence of health facilities serving street-connected children have left this vulnerable group engaging in high-risk behaviors exposing them to acquiring HIV. This cross-sectional study aimed at estimating the prevalence of HIV infection and its associated risk factors among street-connected children aged between 10 to17 years in Mwanza City. The study was granted ethical clearance all permissions and restrictions to work with …


Everyday Life With Childhood Functional Constipation: A Qualitative Phenomenological Study Of Parents' Experiences, Gunilla Flankegård, Evalotte Mörelius, Patrik Rytterström Nov 2022

Everyday Life With Childhood Functional Constipation: A Qualitative Phenomenological Study Of Parents' Experiences, Gunilla Flankegård, Evalotte Mörelius, Patrik Rytterström

Research outputs 2022 to 2026

Childhood functional constipation (FC) is a worldwide problem with treatment regiments affecting everyday life. Aim: To explore parents´ experiences of living with a child with FC and its impact on everyday family life. Method: A qualitative phenomenological interview study using a reflective lifeworld research approach. Interviews with 15 parents of otherwise healthy children aged 1–14 years affected by FC. Findings: Shame is the driving force making parents put everyday life on hold. The quest for control, self-imposed loneliness, guilt, inadequacy, and frustrating battles become essential parts of everyday life to protect it from FC-related shame. Conclusion: FC has as great …


Prevalence Of Metabolic Syndrome In School-Aged Obese Children, Maha A. Tawfik, Mohamed A Abdo Al-Fiqi, Soheir S. Abou El-Ella, Zeinab S. Abou Zouna Oct 2022

Prevalence Of Metabolic Syndrome In School-Aged Obese Children, Maha A. Tawfik, Mohamed A Abdo Al-Fiqi, Soheir S. Abou El-Ella, Zeinab S. Abou Zouna

Menoufia Medical Journal

Objective To evaluate the prevalence of metabolic syndrome (MS) in a group of school-aged obese children of both sexes. Background Data about MS in children are limited in Egypt as the prevalence and magnitude of obesity among school-aged children has been increasing dramatically. We examined the effect of varying degrees of obesity on the prevalence of the MS. Patients and methods This cross-sectional study was conducted on obese children (BMI ≥ 95th percentile), aged 6–16 years. Detailed history taking with family pedigree; complete systemic examination; anthropometric measurements, including weight (kg) on Z score, height (m) on Z score, waist …


Clinical Assessment And Follow-Up Of School-Aged Diabetic Children, Kamel Gomaa, Maha A. Tawfik, Soheir S. A. El-Ella, Zeinab S. Abouzouna Oct 2022

Clinical Assessment And Follow-Up Of School-Aged Diabetic Children, Kamel Gomaa, Maha A. Tawfik, Soheir S. A. El-Ella, Zeinab S. Abouzouna

Menoufia Medical Journal

Objective Clinical assessment and follow-up in school-aged diabetic children. Background Diabetes mellitus requires continuous medical care, patient self-management, education, and support to prevent acute complications and to reduce long-term complications. Patients and methods This descriptive study was conducted on 110 diabetic Egyptian children. All patients were subjected to detailed history taking, complete general examination including anthropometric measurements and laboratory investigations including estimation of fasting blood glucose level (mg/dl), postprandial blood glucose level (mg/dl), glycosylated hemoglobin (HbA1c%), lipid profile (cholesterol, low-density lipoprotein, and triglyceride), microalbumin in urine, and thyroid function (thyroid-stimulating hormone and FT4). Results The mean age of the studied …


Neuroglobin As A Novel Biomarker In Childhood Seizures, Heba B. Abd Elsalam, Sameh A. Abd Elnaby, Sara M. Eldeeb, Yasmeen K E. El-Fiky Oct 2022

Neuroglobin As A Novel Biomarker In Childhood Seizures, Heba B. Abd Elsalam, Sameh A. Abd Elnaby, Sara M. Eldeeb, Yasmeen K E. El-Fiky

Menoufia Medical Journal

Objectives The aim of this study is to investigate the possible role of neuroglobin as a novel biomarker in children with febrile seizures and epileptic children. Background Neuroglobin is a new globin member that is highly expressed in the central and peripheral nervous system. Patients and methods This case–control study has been conducted on 75 children, divided into three groups: group I included children with simple febrile convulsions, group II included children with newly diagnosed idiopathic epilepsy, and group III included healthy children selected as controls. Serum neuroglobin assay, complete blood count, C-reactive protein level, random blood sugar, serum electrolytes, …