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Full-Text Articles in Medicine and Health Sciences
Diagnostic Efficacy Of Routine Contrast-Enhanced Abdominal Ct For The Assessment Of Osteoporosis In The Turkish Population, Ayşegül Cansu, Di̇lara Atasoy, İlker Eyüboğlu, Murat Karkucak
Diagnostic Efficacy Of Routine Contrast-Enhanced Abdominal Ct For The Assessment Of Osteoporosis In The Turkish Population, Ayşegül Cansu, Di̇lara Atasoy, İlker Eyüboğlu, Murat Karkucak
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the diagnostic efficacy of vertebral Hounsfield unit (HU) values on routine contrast-enhanced abdominal computed tomography (CT) scans for the assessment of osteoporosis using dual-energy X-ray absorptiometry (DXA) T-scores as a reference standard.Materials and methods: A total of 111 consecutive patients who underwent contrast-enhanced abdominal CT examination for any indication and DXA within a 6-month period were retrospectively analyzed. The CT attenuation values of trabecular bone in HUs were measured in axial and sagittal planes from lumbar vertebrae 1-4 (L1-L4). The correlation between the DXA T-scores and HU values measured on the CT scans was …
Neuropeptide Y1 Receptor Antagonist But Not Neuropeptide Y Itself Increased Bone Mineral Density When Locally Injected With Hyaluronic Acid In Male Wistar Rats, Muhammer Özgür Çevi̇k, Petek Korkusuz, Feza Korkusuz
Neuropeptide Y1 Receptor Antagonist But Not Neuropeptide Y Itself Increased Bone Mineral Density When Locally Injected With Hyaluronic Acid In Male Wistar Rats, Muhammer Özgür Çevi̇k, Petek Korkusuz, Feza Korkusuz
Turkish Journal of Medical Sciences
Background/aim: The nervous system controls bone mass via both the central (CNS) and the peripheral (PNS) nervous systems. Intriguingly, neuropeptide Y (NPY) signaling occurs in both. Less is known on how the PNS stimulated NPY signaling controls bone metabolism. The objective of this study was to evaluate whether NPY or NPY1 receptor antagonist changes local bone mineral density (BMD) when injected into a Wistar rat tibia. Materials and methods: Tibial intramedullary area of 24 wild type male Wistar rats (average weight = 350 ± 50 g, average age = 4 ± 0.5 months) were injected with NPY (1 × 10-5 …
Evaluation Of The Effects Of Ss1-Selective Beta-Blockers On Bone Mineral Density And Fracture Risk In Postmenopausal Women, Betül Yavuz Keleş, Meltem Vural, Burcu Önder, Kadri̇ye Öneş
Evaluation Of The Effects Of Ss1-Selective Beta-Blockers On Bone Mineral Density And Fracture Risk In Postmenopausal Women, Betül Yavuz Keleş, Meltem Vural, Burcu Önder, Kadri̇ye Öneş
Turkish Journal of Medical Sciences
Background/aim: ß1-selective beta-blockers (BBs) are sympatholytic agents, and discerning their effects on bone health would be of great importance. This study aimed to investigate the influence of ß1-selective BBs on bone mineral density (BMD) and fracture risk. Materials and methods: This study included postmenopausal women who used ß1-selective BBs (BB group) and control group. Sociodemographic characteristics, BMD and previous fragility fractures were recorded. Additionally, the 10-year probability of a major osteoporotic and hip fracture was calculated using the fracture risk assessment tool (FRAX). Results: A total of 60 participants were included in the study. L1-4 and L2-4 BMD values were …