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Full-Text Articles in Medicine and Health Sciences
Diagnostic Efficacy Of Routine Contrast-Enhanced Abdominal Ct For The Assessment Of Osteoporosis In The Turkish Population, Ayşegül Cansu, Di̇lara Atasoy, İlker Eyüboğlu, Murat Karkucak
Diagnostic Efficacy Of Routine Contrast-Enhanced Abdominal Ct For The Assessment Of Osteoporosis In The Turkish Population, Ayşegül Cansu, Di̇lara Atasoy, İlker Eyüboğlu, Murat Karkucak
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the diagnostic efficacy of vertebral Hounsfield unit (HU) values on routine contrast-enhanced abdominal computed tomography (CT) scans for the assessment of osteoporosis using dual-energy X-ray absorptiometry (DXA) T-scores as a reference standard.Materials and methods: A total of 111 consecutive patients who underwent contrast-enhanced abdominal CT examination for any indication and DXA within a 6-month period were retrospectively analyzed. The CT attenuation values of trabecular bone in HUs were measured in axial and sagittal planes from lumbar vertebrae 1-4 (L1-L4). The correlation between the DXA T-scores and HU values measured on the CT scans was …
Evaluation Of The Effects Of Ss1-Selective Beta-Blockers On Bone Mineral Density And Fracture Risk In Postmenopausal Women, Betül Yavuz Keleş, Meltem Vural, Burcu Önder, Kadri̇ye Öneş
Evaluation Of The Effects Of Ss1-Selective Beta-Blockers On Bone Mineral Density And Fracture Risk In Postmenopausal Women, Betül Yavuz Keleş, Meltem Vural, Burcu Önder, Kadri̇ye Öneş
Turkish Journal of Medical Sciences
Background/aim: ß1-selective beta-blockers (BBs) are sympatholytic agents, and discerning their effects on bone health would be of great importance. This study aimed to investigate the influence of ß1-selective BBs on bone mineral density (BMD) and fracture risk. Materials and methods: This study included postmenopausal women who used ß1-selective BBs (BB group) and control group. Sociodemographic characteristics, BMD and previous fragility fractures were recorded. Additionally, the 10-year probability of a major osteoporotic and hip fracture was calculated using the fracture risk assessment tool (FRAX). Results: A total of 60 participants were included in the study. L1-4 and L2-4 BMD values were …
Neuropeptide Y1 Receptor Antagonist But Not Neuropeptide Y Itself Increased Bone Mineral Density When Locally Injected With Hyaluronic Acid In Male Wistar Rats, Muhammer Özgür Çevi̇k, Petek Korkusuz, Feza Korkusuz
Neuropeptide Y1 Receptor Antagonist But Not Neuropeptide Y Itself Increased Bone Mineral Density When Locally Injected With Hyaluronic Acid In Male Wistar Rats, Muhammer Özgür Çevi̇k, Petek Korkusuz, Feza Korkusuz
Turkish Journal of Medical Sciences
Background/aim: The nervous system controls bone mass via both the central (CNS) and the peripheral (PNS) nervous systems. Intriguingly, neuropeptide Y (NPY) signaling occurs in both. Less is known on how the PNS stimulated NPY signaling controls bone metabolism. The objective of this study was to evaluate whether NPY or NPY1 receptor antagonist changes local bone mineral density (BMD) when injected into a Wistar rat tibia. Materials and methods: Tibial intramedullary area of 24 wild type male Wistar rats (average weight = 350 ± 50 g, average age = 4 ± 0.5 months) were injected with NPY (1 × 10-5 …
The Effect Of Parathyroidectomy On Bone Mineral Density In Primary Hyperparathyroidism, Mustafa Çalişkan, Selvi̇han Beysel, Muhammed Kizilgül, Mustafa Özbek, Erman Çakal
The Effect Of Parathyroidectomy On Bone Mineral Density In Primary Hyperparathyroidism, Mustafa Çalişkan, Selvi̇han Beysel, Muhammed Kizilgül, Mustafa Özbek, Erman Çakal
Turkish Journal of Medical Sciences
Background/aim: This study aimed to investigate the change in bone mineral density (BMD) before and 1 year after parathyroidectomy in patients with primary hyperparathyroidism (PHPT). Materials and methods: The clinical and biochemical parameters and DEXA screening of patients with symptomatic PHPT (n = 28) and asymptomatic PHPT (n = 63) were investigated before and 1 year after parathyroidectomy. Results: Patients with symptomatic PHPT had a higher prevalence of nephrolithiasis (18.2% vs. 4.6%, P = 0.032) when compared to the prevalence in patients with asymptomatic PHPT. The prevalence of osteoporosis in the lumbar spine (63.0% vs. 37.5%, P = 0.026) and …
Bone Mineral Density And Growth In Children With Coeliac Disease On A Gluten Free-Diet, Ceyda Tuna Kirsaçlioğlu, Zari̇fe Kuloğlu, Aydan Tanca, Nuri̇ye Özlem Küçük, Zehra Aycan, Gönül Öçal, Arzu Ensari̇, Ayhan Gazi̇ Kalayci, Nurten Gi̇rgi̇n
Bone Mineral Density And Growth In Children With Coeliac Disease On A Gluten Free-Diet, Ceyda Tuna Kirsaçlioğlu, Zari̇fe Kuloğlu, Aydan Tanca, Nuri̇ye Özlem Küçük, Zehra Aycan, Gönül Öçal, Arzu Ensari̇, Ayhan Gazi̇ Kalayci, Nurten Gi̇rgi̇n
Turkish Journal of Medical Sciences
Background/aim: To evaluate changes in growth and bone metabolism during consumption of a gluten-free diet (GFD) in children with coeliac disease (CD). Materials and methods: Thirty-seven children with CD (mean age of 8.8 ± 4.6 years, 21 girls) were enrolled. Anthropometric measurements, bone mineral density (BMD) in lumbar 2-4 vertebrae, and serum alkaline phosphatase, calcium, and phosphorus levels at diagnosis and at follow-up were recorded. Results: The mean follow-up period was 3.5 ± 2.3 years. The BMD of patients was significantly lower than that of control subjects at the time of diagnosis but not after 1 year of the GFD. …
Sp1 Binding Site Polymorphism Of A Collagen Gene (Rs 1800012) In Womenaged 45 And Over And Its Association With Bone Density, Morteza Dehghan, Razieh Pourahmad-Jaktaji
Sp1 Binding Site Polymorphism Of A Collagen Gene (Rs 1800012) In Womenaged 45 And Over And Its Association With Bone Density, Morteza Dehghan, Razieh Pourahmad-Jaktaji
Turkish Journal of Medical Sciences
Background/aim: Sp1 polymorphism of type I collagen genes is accompanied with bone c??ollagen disorders and severe clinical phenotypes such as osteogenesis imperfecta. The aim of this study was to study the association between COLIA1 Sp1 polymorphism and bone density rate. Materials and methods: In this descriptive, analytical study conducted in 2013 in southwestern Iran, 200 blood samples, per the Cochran sample size formula, were taken from women aged 45 and older. DNA was extracted from the samples using the phenol-chloroform method and the genomic fragments in question were proliferated using the polymerase chain reaction (PCR) method. Results: The genotype distribution …
The Effect Of Swimming And Type Of Stroke On Bone Metabolism In Competitiveadolescent Swimmers: A Pilot Study, Si̇nem Akgül, Nuray Kanbur, Şükrü Alpan Ci̇nemre, Erdem Karabulut, Orhan Derman
The Effect Of Swimming And Type Of Stroke On Bone Metabolism In Competitiveadolescent Swimmers: A Pilot Study, Si̇nem Akgül, Nuray Kanbur, Şükrü Alpan Ci̇nemre, Erdem Karabulut, Orhan Derman
Turkish Journal of Medical Sciences
Background/aim: Physical activity plays a key role in increasing and preserving bone mineral density (BMD). Effects on bone development associated with various nonweight-bearing sporting activities, such as swimming, are controversial. Different strokes used in swimming may also present as another factor. The aim of this study was to evaluate the effect of swimming and type of stroke on BMD in competitive adolescent athletes. Materials and methods: Seventy-nine swimmers between the ages of 10 and 21 years participated in this study. BMD was measured with dual-energy X-ray absorptiometry at the lumbar vertebrae and left proximal femur. Daily calorie intake and calcium …
Bone Mineral Density And Vitamin D Status In Children And Adolescents With Congenital Adrenal Hyperplasia, Fatma Demi̇rel, Özlem Kara, Derya Tepe, İhsan Esen
Bone Mineral Density And Vitamin D Status In Children And Adolescents With Congenital Adrenal Hyperplasia, Fatma Demi̇rel, Özlem Kara, Derya Tepe, İhsan Esen
Turkish Journal of Medical Sciences
To determine the prevalence of and risk factors for decreased bone mineral density (BMD) and vitamin D deficiency in children and adolescents with congenital adrenal hyperplasia (CAH). Materials and methods: This study was conducted on 30 girls and 22 boys with CAH (age range = 5-20 years) with median age of 12.0 years. BMD values of lumbar vertebras (L1-L4), which were determined by dual-energy X-ray absorptiometry, were used to calculate z-scores according to chronological age. A serum 25-hydroxyvitamin D level of
Serum Fetuin-A Levels In Postmenopausal Women With Osteoporosis, Esi̇n Özkan, Hüseyi̇n Özkan, Serkan Bi̇lgi̇ç, Ersi̇n Odabaşi, Nuray Can, Emi̇n Özgür Akgül, İbrahi̇m Yanmiş, Yüksel Yurttaş, Mustafa Kürklü, Mustafa Başbozkurt, Mehmet Kemal Erbi̇l
Serum Fetuin-A Levels In Postmenopausal Women With Osteoporosis, Esi̇n Özkan, Hüseyi̇n Özkan, Serkan Bi̇lgi̇ç, Ersi̇n Odabaşi, Nuray Can, Emi̇n Özgür Akgül, İbrahi̇m Yanmiş, Yüksel Yurttaş, Mustafa Kürklü, Mustafa Başbozkurt, Mehmet Kemal Erbi̇l
Turkish Journal of Medical Sciences
One of the functions of fetuin-A is the restriction of formation and expansion of extraosseous hydroxyapatite crystals. The exact correlation of fetuin-A with bone mineral density (BMD) has not been clearly elucidated yet. In this study, we aimed to assess the relationship between BMD and fetuin-A in postmenopausal women. Materials and methods: Fifty postmenopausal women (25 with osteoporosis, 25 healthy controls) were included in the study. All participants were comparable for age and body mass index. None of the osteoporotic patients had received any medical treatment for osteoporosis. Serum fetuin-A levels were measured by ELISA method. Results: BMD scores of …
Effect Of Lactation On Bone Mineral Density Later In Life In Turkish Women, Orhan Aksakal, Hakan Aytan, Sabri̇ Cavkaytar, Ömer Lütfi̇ Tapisiz, Tayfun Güngör, Bülent Özdal, Leyla Mollamahmutoğlu
Effect Of Lactation On Bone Mineral Density Later In Life In Turkish Women, Orhan Aksakal, Hakan Aytan, Sabri̇ Cavkaytar, Ömer Lütfi̇ Tapisiz, Tayfun Güngör, Bülent Özdal, Leyla Mollamahmutoğlu
Turkish Journal of Medical Sciences
Aim: To investigate the probable effect of lactation on bone mineral density (BMD) later in life. Materials and Methods: Eighty-seven premenopausal and 18 postmenopausal Turkish women were classified into four groups according to age. Age, height, weight, menopausal status, age at menopause (in postmenopausal women), years since menopause (in postmenopausal woman), parity and total lactation period were recorded. Lumbar spine BMD (L2-L4) was measured by dual-energy X-ray absorptiometry (DEXA). In each group, correlations of lactation with BMD were investigated using Pearson correlation test, and multiple regression analyses were used to determine the factors associated with BMD. Results: No significant correlation …
The Effect Of Isoflavones On Bone Mass And Bone Remodelling Markers In Postmenopausal Women, Ni̇lgün Öztürk Turhan, Fatma Bolkan, Candan İltemi̇r Duvan, Yasemi̇n Ardiçoğlu
The Effect Of Isoflavones On Bone Mass And Bone Remodelling Markers In Postmenopausal Women, Ni̇lgün Öztürk Turhan, Fatma Bolkan, Candan İltemi̇r Duvan, Yasemi̇n Ardiçoğlu
Turkish Journal of Medical Sciences
Aim: Recently, isoflavones have attracted attention for their potential roles in the prevention and treatment of estrogen-related osteoporosis. However, the optimal dosage and the components responsible for the favorable effects of isoflavones on bone in humans are still unclear. This study aims to investigate the effect of low-dose isoflavones on bone mineral density (BMD) and on biochemical markers of bone turnover in early postmenopausal women. Materials and Methods: Ninety participants between 42-59 years of age were randomly assigned to receive twice a day either isoflavone tablet (n:45) that provided 29.8 mg genistein, 7.8 mg daidzein, and 2.4 mg glycitein per …
Diagnostic Performance Of Qus For Identifying Osteoporosis In Postmenopausal Turkish Women, Ayfer Gemalmaz, Güzel Di̇şci̇gi̇l, Cengi̇z Ceylan
Diagnostic Performance Of Qus For Identifying Osteoporosis In Postmenopausal Turkish Women, Ayfer Gemalmaz, Güzel Di̇şci̇gi̇l, Cengi̇z Ceylan
Turkish Journal of Medical Sciences
Aim: The aims of this study were to evaluate the ability of quantitative ultrasound (QUS) to identify osteoporosis in postmenopausal women on the basis of dual-energy X-ray absorptiometry (DXA) T-scores, the best predictor of osteoporotic fractures, and to find a cut-off value for QUS with the optimum sensitivity and specificity, in order to select postmenopausal women for DXA referral. Materials and Methods: This study included 116 postmenopausal women attending Adnan Menderes University Family Medicine Clinic in Aydin. Bone density was measured at the calcaneus using QUS and at lumbar spine and femoral neck with DXA. Receiver operating characteristic analysis was …
The Effects Of Tooth Extraction On Cortical Thickness And Bone Mineral Density Of The Mandible: Evaluation With Computerized Tomography, Pinar Polat, Gözlem Ceylan, Selami̇ Suma, Nuran Yanikoğlu
The Effects Of Tooth Extraction On Cortical Thickness And Bone Mineral Density Of The Mandible: Evaluation With Computerized Tomography, Pinar Polat, Gözlem Ceylan, Selami̇ Suma, Nuran Yanikoğlu
Turkish Journal of Medical Sciences
The cortical thickness of the mandible (CTM) and its bone mineral density may be affected by tooth extraction. There is little knowledge of how the number of teeth in the mandible affect the cortical thickness and bone mineral density of the mandible in 2 different parts. The purpose of this study was to demonstrate whether there is any relationship between the number of teeth extracted and the cortical thickness and bone mineral density of the mandible. A total of 64 cases were evaluated in this study. The patients were divided into four groups. Group 1 consisted of 24 patients who …