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Full-Text Articles in Medicine and Health Sciences
The Level Of Ferritin In Diabetic And Nondiabetic Patients With Acute Myocardial Infarction, Meral Mert, Müge Korkmaz, Mustafa Temi̇zel, Meti̇n Acar
The Level Of Ferritin In Diabetic And Nondiabetic Patients With Acute Myocardial Infarction, Meral Mert, Müge Korkmaz, Mustafa Temi̇zel, Meti̇n Acar
Turkish Journal of Medical Sciences
An elevated serum ferritin level is proposed as a risk factor for coronary heart disease. The role of diabetes mellitus on serum ferritin levels in myocardial infarction has recently been investigated. The purpose of this study was to assess the effects of diabetes mellitus on serum ferritin levels in patients with acute myocardial infarction (AMI). In this study, we studied patients (104 nondiabetic, 26 diabetic patients) with acute myocardial infarction (AMI). AMI was diagnosed according to typical clinical history, ECG changes and cardiac enzyme elevations. Blood samples for ferritin, iron and total iron binding capacity (TIBC) and haemogram tests were …
Duration Of Streptozotocin-Induced Diabetes Differentially Affects P38-Mitogen-Activated Protein Kinase (Mapk) Phosphorylation In Renal And Vascular Dysfunction, H. Chen, S. Brahmbhatt, A. Gupta, Avadhesh C. Sharma
Duration Of Streptozotocin-Induced Diabetes Differentially Affects P38-Mitogen-Activated Protein Kinase (Mapk) Phosphorylation In Renal And Vascular Dysfunction, H. Chen, S. Brahmbhatt, A. Gupta, Avadhesh C. Sharma
PCOM Scholarly Papers
Background: In the present study we tested the hypothesis that progression of streptozotocin (STZ)-induced diabetes (14-days to 28-days) would produce renal and vascular dysfunction that correlate with altered p38- mitogen-activated protein kinase (p38-MAPK) phosphorylation in kidneys and thoracic aorta. Methods: Male Sprague Dawley rats (350-400 g) were randomized into three groups: sham (N = 6), 14-days diabetic (N = 6) and 28-days diabetic rats (N = 6). Diabetes was induced using a single tail vein injection of STZ (60 mg/kg, I.V.) on the first day. Rats were monitored for 28 days and food, water intake and plasma glucose levels were …