Medicine and Health Sciences Commons^™

Case Studies For Dentistry®: Development Of A Tool To Author Interactive, Multimedia, Computer-Based Patient Simulations, Louis M. Abbey, Pamela Arnold, Lucy Halunko, Mary Beth Huneke, Stacie Lee

Oral and Maxillofacial Surgery Publications

Computer-based patient simulations have been used to enhance the dental curriculum since the 1980s. This article describes the development of CASE STUDIES for Dentistry (CSD), a patient case simulation building template, developed at Virginia Commonwealth University, with which authors who have no programming expertise can create realistic, effective, interactive multimedia patient simulations by entering their own information and images into a straightforward, fill in the blanks interface. This program was written with Authorware, by Macromedia Inc. Design considerations included emphasis on information collection and analysis, synthesis of collected information, hypothesis proposal and testing, diagnosis, and treatment planning. The program consists …

Bekm-1 Is A Herg-Specific Toxin That Shares The Structure With Chtx But The Mechanism Of Action With Ergtx1, Mei Zhang, Yuliya V. Korolkova, Jie Liu, Min Jiang, Eugene V. Grishin, Gea-Ny Tseng

Physiology and Biophysics Publications

ABSTRACT

Peptide toxins with disulfide-stabilized structures have been used as molecular calipers to probe the outer vestibule structure of K channels. We want to apply this approach to the human ether-a-go-go-related gene (HERG) channel, whose outer vestibule is unique in structure and function among voltage-gated K channels. Our focus here is BeKm-1, a HERG-specific peptide toxin that can suppress HERG in the low nM concentration range. Although BeKm-1 shares the three-dimensional scaffold with the well-studied charybdotoxin, the two use different mechanisms in suppressing currents through their target K channels. BeKm-1 binds near, but not inside, the HERG pore, and it …

Adefovir Dipivoxil For The Treatment Of Hepatitis B E Antigen–Positive Chronic Hepatitis B, Patrick Marcellin , M.D., Ting-Tsung Chang , M.D., Seng Gee Lim , M.D., Myron J. Tong , Ph.D., M.D., William Seivert , M.D., Mitchell L. Shiffman , M.D., Lennox Jeffers , M.D., Zachary Goodman , M.D., Ph.D., Michael S. Wulfsohn , M.D., Ph.D., Shelly Xiong , Ph.D., John Fry , B.Sc., Carol L. Brosgart , M.D.

Internal Medicine Publications

BACKGROUND

In preclinical and phase 2 studies, adefovir dipivoxil demonstrated potent activity against hepatitis B virus (HBV), including lamivudine-resistant strains.

METHODS

We randomly assigned 515 patients with chronic hepatitis B who were positive for hepatitis B e antigen (HBeAg) to receive 10 mg of adefovir dipivoxil (172 patients), 30 mg of adefovir dipivoxil (173), or placebo (170) daily for 48 weeks. The primary end point was histologic improvement in the 10-mg group as compared with the placebo group.

RESULTS

After 48 weeks of treatment, significantly more patients who received 10 mg or 30 mg of adefovir dipivoxil per day than …

The Effect Of Chlorhexidine Gluconate As An Endodontic Irrigant On The Apical Seal: Long-Term Results, David B. Ferguson

Theses and Dissertations

The purpose of this study was to determine whether chlorhexidine gluconate (0.12%), used as an endodontic irrigating solution would affect the apical seal of three root canal cements. One hundred extracted human single-canal teeth were divided into 9 experimental groups of 10 teeth each, in addition to a positive and negative control group of 5 teeth each. The teeth were decoronated at the level of the cementoenamel junction, accessed, instrumented to a Master Apical File #50, irrigated with either sterile saline, 5.25% NaOCl or 0.12% chlorhexidine gluconate, and dried using paper points. Obturation was accomplished using lateral condensation and one …

Parent Perceptions Of Occupational Therapy In Early Childhood Special Education Programs Following Transition From Early Intervention Programs, Anita M. Wyrick

Theses and Dissertations

A qualitative approach was used to explore the perspectives of seven parents of preschool age children with disabilities in Virginia regarding occupational therapy and the transition from early intervention (EI) to early childhood special education (ECSE). Open-ended interviews were used to collect data from each family participant and were presented as individual case reports. A cross-case analysis revealed six common categories and four overarching themes. Results indicated that the transition was viewed positively when parents saw benefits of the change and when they were oriented toward the future. Parents viewed the EI and ECSE systems as not sharing their same …

A Rural Vs. Urban Analysis Of Procedures Provided To Medicaid Recipients By Pediatric, General, And Public Health Dentists In The Commonwealth Of Virginia: Fiscal Years 1994-1995, Frank Carmen Pettinato

Theses and Dissertations

Purpose: The purpose of this study was to report the distribution of procedures provided to Virginia Medicaid children by three types of dental providers in rural and urban areas. Methods: Medicaid claims filed for dental patients younger than 21 were obtained and analyzed for fiscal years 1994 and 1995. Dental providers were categorized according to their practice type: general practice (GP), pediatric (PD) and public health (PH) dentists. Each type of practice was categorized as practicing in a Metropolitan, Urban, Rural or Completely Rural location and evaluated for percentages of preventive, diagnostic, and corrective services provided.Results: The number of procedures …

Measurement Of Forces And Moments In Three-Dimensional Archwires, Dwight Van Buelow

Theses and Dissertations

AbstractMEASUREMENT OF FORCES AND MOMENTS IN THREE-DIMENSIONAL ARCHWIRESBy Dwight V. Buelow, D.D.S.A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University.Virginia Commonwealth University, 2003Major Director: Steven J. Lindauer, D.M.D., M.D.Sc.Chairman and Professor, Department of OrthodonticsOrthodontic tooth movement occurs in response to the application of controlled mechanical force systems. The purpose of this study was to improve understanding of those force systems by evaluating differences between the resultants of two-dimensional and three-dimensional orthodontic appliance activations. An in-vitro model was constructed and three force-moment gauges were used to measure the forces and …

K3 Endo, Pro Taper, And Pro File Systems: Breakage And Distortion In Severely Curved Roots Of Molars, Matthew Todd Ankrum

Theses and Dissertations

K3 ENDO, PRO TAPER, AND PRO FILE SYSTEMS: BREAKAGE AND DISTORTION IN SEVERELY CURVED ROOTS OF MOLARS.By Matthew T. Ankrum, D.D.S.A Thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University.Virginia Commonwealth University, 2003Major Director: Gary R. Hartwell, D.D.S., M.S.Chairman and Professor, Department of EndodonticsIt was the aim of this study to investigate the incidence of file breakage and distortion when the Pro Taper, K3 Endo and ProFile systems were used to instrument canals in the severely curved roots of extracted molars.Forty-five roots of extracted mandibular and maxillary molars with curvatures …

The Ca2+ Dynamics Of Isolated Mouse Β-Cells And Islets: Implications For Mathematical Models, Min Zhang, Paula Goforth, Richard Bertram, Arthur Sherman, Leslie S. Satin

Pharmacology and Toxicology Publications

ABSTRACT

[Ca²⁺]_i and electrical activity were compared in isolated β-cells and islets using standard techniques. In islets, raising glucose caused a decrease in [Ca²⁺]_i followed by a plateau and then fast (2–3 min⁻¹), slow (0.2–0.8 min⁻¹), or a mixture of fast and slow [Ca²⁺]_i oscillations. In β-cells, glucose transiently decreased and then increased [Ca²⁺]_i, but no islet-like oscillations occurred. Simultaneous recordings of [Ca²⁺]_i and electrical activity suggested that differences in [Ca²⁺]_i signaling are due to …

Montessori-Based Activities For Dementia: A Walk Down Memory Lane, Janina C. Bognar

Case Studies from Age in Action

Educational Objectives

1. Familiarize readers with the Montessori method as used with participants who have dementia.

2. Demonstrate the role of Montessori-based activities for dementia in an adult day care setting.

The Value Of Multidisciplinary Care In Parkinson's Disease, Miriam Hirsch, Mark Baron

Case Studies from Age in Action

Educational Objectives

1. To recognize the signs and symptoms of Parkinson's disease (PD).

2. To identify key treatment and management strategies for PD.

3. To discuss the importance of multidisciplinary care and the need for individualized treatment of PD.

Abuse, Neglect, And Exploitation Of Vulnerable Elders, Sheila Crossen-Powell, Kira R. Holland, Marjorie L. Marker

Case Studies from Age in Action

Educational Objectives

1. To describe the variety and dynamics of self-neglect and abuse.

2. To illustrate cases of familial self-neglect and of financial exploitation.

3. To demonstrate the roles that Adult Protective Services (APS) plays in the investigation of adult abuse, neglect, and exploitation.

4. To describe the protections available to vulnerable adults in the Commonwealth.

Aging In Place -- Can Universal Design Make It A Reality?, Helen Eltzeroth

Case Studies from Age in Action

Educational Objectives

1. Comprehend the principles of universal design

2. Understand the barriers to aging in place

3. Learn what resources are available to facilitate aging in place

Virginia Dental Journal (Vol. 80, No. 3, 2003)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 80, No. 4, 2003)

Virginia Dental Journal

No abstract provided.

Evaluation Of Shear Bond Strength Of Two Resin-Modified Glass-Ionomer Cements, Emily Y. Ro

Theses and Dissertations

Purpose: To compare the in-vitro shear bond strengths of a new paste-paste formulation of resin-modified glass-ionomer cement (Rm-GIC) to an exising powder-liquid formulation. The study will test the hypothesis that the new paste-paste formulation of Rm-GIC (Fuji-Cem ™, GC Corp, Tokyo, Japan) has the same bond strength as an existing popular powder-liquid formulation of Rm-GIC (Rely-X ™ Luting Cement, 3M, St. Paul, MN)Materials and Methods: A total of 33 human molars were sectioned parallel to the occlusal surface to expose mid-coronal dentin and mounted parallel to the bond shearing device on the universal testing machine (Instron). For Group I samples …

Utilization Of The Vacuum Form Machine: Custom Mouthguards Versus Esthetic Bleaching Trays, Jacqueline Michele Carney

Theses and Dissertations

Purpose: This study analyzed the percentage of Virginia practitioners utilizing vacuum form machines, types of appliances recommended, and types of patient information provided.Methods: Questionnaires were constructed and mailed to 2500 dentists.Results: 80% of dentists utilized vacuum form machines, 42.5% recommended mouthguards, 60.2% recommended home bleaching trays, 37.6% provided patient information on mouthguards, 37.1% provided patient information on home bleaching trays, 16.5% inquired on patient questionnaires about mouthguard protection during contact sports,and 17.3% inquired on patient questionnaires about tooth color satisfaction.Conclusions: Dentists use vacuum form machines for home bleaching trays more than mouthguards. General dentists and pediatric dentists provide patient information …

Mechanisms Underlying Protection Against Rt-2 Gliomagenesis In Rat Brain Utilizing Primary And Secondary Vaccination, Andrea M. Lister

Theses and Dissertations

Primary brain tumor affects some 18,000 adults in the United States each year (Silverberg et al., 1990; Merchant et al., 1997) and over 30% are high-grade anaplastic astrocytoma or glioblastoma multiforme (GBM) (Parney et al., 1997). According to Kruse et al., 1989, the treatment of patients with recurrent or persistent high-grade gliomas represents a major therapeutic challenge. The use of conventional therapy consisting of surgery, followed by radiation therapy and chemotherapy for gliomas, has been relatively ineffective (Jaecle et al., 1994) despite the fact that these therapies are cytoreductive in nature (Black, 1991). Most malignancies will recur locally but may …

An In-Vitro Comparison Of The Retention Of Prefabricated Parallel-Sided Vented Titanium Posts Cemented With Three Different Dual-Polymerizable Resin Cements, Maha Mamdouh Mostafa El-Sayed

Theses and Dissertations

AbstractAN IN-VITRO COMPARISON OF THE RETENTION OF PREFABRICATED PARALLEL-SIDED VENTED TITANIUM POSTS CEMENTED WITH THREE DIFFERENT DUAL-POLYMERIZABLE RESIN CEMENTSBy Maha M. El-Sayed, B.D.S., D.M.D.A Thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University.Virginia Commonwealth University, 2003Thesis Director: David R. Burns, D.M.D. Associate Professor and Program DirectorGraduate ProsthodonticsDepartment of ProsthodonticsPurpose: The purpose of this in-vitro study was to compare the retentive strength of an autopolymerizing resin cement to three dual-polymerizable resin cements when used to cement paraposts without light activation and to relate diametral tensile stress and hardness as a measure …

The Effect Of Endodontic Solutions On Resorcinol-Formalin Paste In Teeth, Madelyn Gay Gambrel

Theses and Dissertations

This study determined if any of six endodontic solutions would have a softening effect on resorcinol-formalin paste in extracted teeth, and if there were any differences in the solvent action between these solutions. Forty-nine single-rooted extracted teeth were decoronated two mm coronal to the CEJ, and the roots sectioned apically to a standard length of 15 mm. Canals were prepared to a 12mm WL and a uniform size with a #7 Parapost drill. Teeth were then mounted in a cylinder ring with acrylic. The resorcinol-formalin mixture was placed into the canals and was allowed to set for 60 days in …

Virginia Dental Journal (Vol. 80, No. 1, 2003)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 80, No. 2, 2003)

Virginia Dental Journal

No abstract provided.

Orthodontic Faculty Recruitment And Retention: Goals And Perceptions, Sheldon L. Peck

Theses and Dissertations

There is a shortage of faculty in academic dentistry and orthodontics in particular. The purpose of this study was to quantify real and perceived differences in income, workload, and satisfaction between full-time academic and private practice orthodontists. Surveys were returned by 119 (70%) faculty, 79 (36%) private practitioners, and 160 (59%) orthodontic residents. Average annual income for faculty was less than half that of private practitioners. Faculty also reported working significantly more hours per week and taking less vacation time. Though both faculty and practitioners perceived their own jobs to be more satisfying overall, faculty felt academics was more stressful, …

The Relationship Of Metabolic Control To Hardiness, Self-Efficacy, And Perceived Medication Adherence In Adults With Diabetes Mellitus, Ok Chon Allison

Theses and Dissertations

Diabetes mellitus, a serious and costly disease, is a public health challenge. Diabetes is controllable, yet non-adherence to prescribed medications causes diabetesrelated complications resulting in hospital admissions and readmissions that may be prevented. A cross-sectional, descriptive-correlational study was conducted to investigate the relationship of metabolic control (A1C) to hardiness, self-efficacy, and perceived medication adherence. Health-Related Hardiness Scale (Pollock, 1990); Long-Term Medication Behavior Self-Efficacy Scale (De Geest et al., 1994); and Perceived Medication Adherence Scale (Allison, 2000) were administered to 215 participants. Data analyses of correlation and multiple linear regression using SPSS 10.0 statistical software were performed. Metabolic control was not …

Nursing Home Staffing Adequacy, Rehabilitation Orientation And Quality, Diana Gilroy Venskus

Theses and Dissertations

Objective: The primary objective of this research is to examine how changing levels of nursing home staffing adequacy and variations in rehabilitation orientation have affected facility deficiencies and the quality of patient care as facilities responded to the Balanced Budget Act of 1997.
Data Sources: Analyses were performed using data from the On-Line Survey Certification and Reporting System (OSCAR) data from years 1997, 1998, 1999, 2000 and 2001 and were merged with Area Resource File (ARF) data released in February 2001.
Study Design: Contingency strategic adaptation provides the theoretical framework for developing the effects of environmental characteristics, organizational characteristics and …

Factors Associated With Metabolic Syndrome, Patricia Marie Selig

Theses and Dissertations

The metabolic syndrome, a clinical condition linked to diabetes and cardiovascular disease is a powerful predictor for overall mortality, and is present in more than 20% of the US. population (Ford, Giles, & Dietz, 2002). This study examines gender differences as well as other factors associated with metabolic syndrome as defined by the Adult Treatment Panel III of the National Cholesterol Education Program.

A sample of 10,134 adults between 20-64 years of age was selected from the Third National Health and Nutrition Survey. Metabolic syndrome was present in 19.6 % of this sample. An ecological model of health services was …

The Bond Strength Of Adhesive Resin Cement: Time Differential Between Cementation And Finishing Of Cast Dowel-Cores, Purnima Joan Shahani

Theses and Dissertations

THE BOND STREGTH OF ADHESIVE RESIN CEMENT: TIME DIFFERENTIAL BETWEEN CEMENTATION AND FINISHING OF CAST DOWEL-CORES By Purnima Joan Shahani, D.D.S., M.S.A Thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Dentistry at Virginia Commonwealth University.Virginia Commonwealth University, 2003Major Director: Peter C. Moon, M.S., PhDDirector of VCU Dental Biomaterials LaboratoryThis study compared the retention of cast dowel-cores cemented with Panavia® 21 subjected to immediate versus delayed high-speed finishing. Conventionally, finishing is delayed for 24 hours to one week to allow for optimal setting and ultimate strength of the cement. Forty-five recently extracted human …

Lip Profile Preferences In Varying Sagittal Mandibular Positions, Grant Gordon Coleman

Theses and Dissertations

The purpose of this study was to determine the influence of sagittal mandibular position on preferred lip position in profile. Five androgynous silhouette profiles differing only in the degree of mandibular retro- or prognathism (-25º, -18º, -11º, -4º, & +3º facial contour angles) were created. Using a computer animation program, evaluators moved the lips independently into the position deemed to be the most esthetic for each profile. Evaluators included adolescent orthodontic patients, parents of patients, and orthodontists. In general, no differences in preferred lip position were found between the –11º & -4º profiles or between the –18º & +3º profiles, …