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Articles 31 - 32 of 32
Full-Text Articles in Medicine and Health Sciences
N-Glycosylation Profiles As A Risk Stratification Biomarker For Type Ii Diabetes Mellitus And Its Associated Factors, Eric Adua
Theses: Doctorates and Masters
Worldwide, the prevalence of cardiometabolic diseases, particularly type II diabetes mellitus (T2DM), and to a lesser extent, metabolic syndrome (MetS), has increased dramatically. Despite this increase, there is still a lack of robust biomarkers for cardiometabolic diseases to secure better clinical outcomes. The enzymatic attachment of oligosaccharides (glycans) to proteins-glycosylation is of metabolic and physiological significance, as exploring aberrations of glycosylation profiles can reveal novel biomarkers. In parallel, this process could also explain the biological mechanisms that underpin a suboptimal health status (SHS), a reversible subclinical stage of a cardiometabolic disease. However, studies on the correlation between glycosylation and MetS/T2DM …
Epidemiological Model Of The Transmission And Spread Of Hepatitis B Pandemic In Ghana, Kwaafo Akoto Awuah-Mensah
Epidemiological Model Of The Transmission And Spread Of Hepatitis B Pandemic In Ghana, Kwaafo Akoto Awuah-Mensah
Theses: Doctorates and Masters
The world's attention to the burden and spread of hepatitis B has increased signicantly in the recent past. A number of interventions by way of treatment and immunisation have been initiated to fight the pandemic, especially in high prevalence regions such as Africa and Asia. Lack of good quality information about hepatitis B is a major hindrance to policy direction and comprehensive implementation of interventions in Sub-Saharan Africa designated as an endemic region. Limited studies on hepatitis B, coupled with lack of adequate health care systems and infrastructure, have led to ignorance or misconceptions and stigmatisation about the disease and …