Medicine and Health Sciences Commons^™

Changes In Temperature Of Heel Skin Under Pressure In Hip Surgery Patients, Vivian K. Wong, N. A. Stotts, H. W. Hopf, G. A. Dowling, E. S. Froelicher

Vivian K. Wong

OBJECTIVE: The aim of the study was to examine the effect of external pressure of the bed surface on heel skin temperature in adults in the first 3 days after hip surgery.

DESIGN: A quasi-experimental study in a prospective, within-subjects, repeated-measures design.

SETTING: This study was performed at 2 acute-care hospitals.

PARTICIPANTS: Eighteen subjects (9 men and 9 women) with a mean age of 58.3 (±16.1) years were recruited after hip surgery at the 2 hospitals.

METHODS: Temperature sensors were placed on the plantar surface of each foot, close to the heels. Measures were taken when the heels were (1) …

Skin Blood Flow Response To 2-Hour Repositioning In The Long-Term Care Residents: A Pilot Study, Vivian K. Wong

Vivian K. Wong

PURPOSE: The purpose of this noninvasive pilot study was to examine the changes in transcutaneous oxygen (tcO2), skin temperature, and hyperemic response in the heels, sacrum, and trochanters in a 2-hour loading-unloading condition in nursing home residents who are positioned in supine and lateral positions.

DESIGN: A 1-group, prospective, repeated-measures design was used.

SUBJECTS AND SETTING: Nine subjects (5 males, 4 females) with a mean age of 85.3 ± 10.86 years (mean ± SD) who required help in turning and positioning at a skilled nursing facility participated in the study.

METHODS: Oxygen and temperature sensors were placed on the heels, …

Efficacy Of A Doxycycline Treatment Regimen Initiated During Three Different Phases Of Experimental Ehrlichiosis, Jennifer C. Mcclure, Michelle L. Crothers, John J. Schaefer, Patrick D. Stanley, Glen R. Needham, S A. Ewing, Roger W. Stich

John J Schaefer

Doxycycline is the treatment of choice for canine monocytic ehrlichiosis (CME), a well-characterized disease and valuable model for tick-borne zoonoses. Conflicting reports of clearance of Ehrlichia canis after treatment with doxycycline suggested that the disease phase during which treatment is initiated influences outcomes of these treatments. The purpose of this study was to evaluate the efficacy of a 28-day doxycycline regimen for clearance of experimental E. canis infections from dogs treated during three phases of the disease. Ten dogs were inoculated with blood from E. canis carriers and treated with doxycycline during acute, subclinical, or chronic phases of CME. Daily …

Overview Of The Essential Tremor, Theresa A. Zesiewicz, Abinaya Chari, Israt Jahan, Amber M. Miller, Kelly L. Sullivan

Kelly L. Sullivan

Essential tremor (ET) is one of the most common movement disorders in the world. Despite this, only one medication (propranolol) is approved by the Food and Drug Administration (FDA) to treat it. Fortunately, recent studies have identified some additional medications as treatment of ET. Surgical procedures, such as deep brain stimulation of the ventral intermediate nucleus of the thalamus, offer treatment for refractory tremor. The epidemiology, pathogenesis, and medical and surgical treatment of ET will be discussed in this paper.

Reduction Of Circulating Endothelial Cells In Peripheral Blood Of Als Patients, Svitlana Garbuzova-Davis, Robert L. Woods Iii, Michael K. Louis, Theresa A. Zesiewicz, Nicole Kuzmin-Nichols, Kelly L. Sullivan, Amber M. Miller, Diana G. Hernandez-Ontiveros, Paul R. Sanberg

Kelly L. Sullivan

Background: Amyotrophic Lateral Sclerosis (ALS) treatment is complicated by the various mechanisms underlying motor neuron degeneration. Recent studies showed that the blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) are compromised in an animal model of ALS due to endothelial cell degeneration. A later study demonstrated a loss of endothelium integrity in the spinal cords of ALS patients. Since circulating endothelial cells (CECs) in the peripheral blood are associated with endothelium damage, being detached dysfunctional endothelial cells, we hypothesized that CEC levels may reflect endothelium condition in ALS patients.
Methodology/Principal Findings: CEC levels were estimated in whole blood smears from …

Ssrn As An Initial Revolution In Academic Knowledge Aggregation And Dissemination, David Bray, Sascha Vitzthum, Benn Konsynski

Sascha Vitzthum

Within this paper we consider our results of using the Social Science Research Network (SSRN) over a period of 18 months to distribute our working papers to the research community. Our experiences have been quite positive, with SSRN serving as a platform both to inform our colleagues about our research as well as inform us about related research (through email and telephoned conversations of colleagues who discovered our paper on SSRN). We then discuss potential future directions for SSRN to consider, and how SSRN might well represent an initial revolution in 21st century academic knowledge aggregation and dissemination. Our paper …

Applicability Of A Video Intervention To Increase Informed Decision Making For Prostate Specific Antigen (Psa) Testing Among African-American Men With Different Levels Of Health Literacy, Levi Ross, Alicestine D. Ashford, Sherese J. Bleechington, Tyra Dark, Deborah C. Erwin

Levi Ross

Purpose: To evaluate the applicability of an evidence-based video intervention to promote informed decision making for prostate cancer (CaP) screening among African-American men with different levels of health literacy.

Methods: Forty nine African-American men participated in interviewer-administered, pretest-posttest interviews between January and March 2008. Health literacy status was assessed with the Test of Functional Health Literacy in Adults (TOFHLA). Repeated measures analysis of covariance (ANCOVA), McNemar or binomial distributions were computed to assess pretest/posttest differences in knowledge. Descriptive statistics were produced to describe participants’ perceptions of the information presented in the video.

Results: Results indicated that men with functional health …

Sleep Disorders In Parkinson's Disease, Israt Jahan, Robert A. Hauser, Kelly L. Sullivan, Amber M. Miller, Theresa A. Zesiewicz

Kelly L. Sullivan

Sleep disorders occur commonly in Parkinson’s disease (PD), and reduce quality of life. Sleep-related problems in PD include insomnia, restless legs syndrome, rapid eye movement sleep behavior disorder, sleep apnea, parasomnias, excessive daytime sleepiness, and sleep attacks. This article reviews sleep disorders and their treatment in PD.

Disparities In The Receipt Of Cardiac Revascularization Procedures Between Blacks And Whites: An Analysis Of Secular Trends, C. Perry, Levi Ross, Ivette Lopez, Angela Thornton, Gebre-Egzib Kiros

Levi Ross

Introduction: Mortality rates for coronary heart disease (CHD) have declined markedly since the early 1970s. However, CHD remains the number one cause of death in the United States. The decline in mortality has been attributed to declines in CHD risk factors (tobacco use, hypertension) and the increase in protective behaviors (exercise, weight control). Medical interventions may have also contributed to the decline in mortality. Despite these declines in mortality, racial disparities persist between Blacks and Whites. The purpose of this study was to examine the differences in receipt of cardiac catheterization, percutaneous transluminal coronary angioplasty, and coronary artery bypass …

Microarray Analysis Demonstrates A Role For Slug In Epidermal Homeostatsis, Kim M. Newkirk

Kim M Newkirk

No abstract provided.

The Acute Cutaneous Inflammatory Response Is Attenuated In Slug Knockout Mice. Newkirk K, Duncan F, Brannick E, Chandler H, Parent A, Kusewitt D., Kim M. Newkirk

Kim M Newkirk

No abstract provided.

Assessing The Professional Development Needs Of Public Health Educators In Light Of Changing Competencies, A. R. Demers, Edward M. Mamary

Edward M. Mamary

Introduction Because of the need for a well-trained public health workforce, professional competencies have been recently revised by the Institute of Medicine and the National Health Educator Competencies Update Project. This study compared the self-identified training needs of public health educators with the updated competencies and assessed employer support for continuing education. Methods A convenience sample of public health educators was recruited from an e-mail list of San Jose State University master of public health alumni. Respondents completed a Web-based survey that elicited information on emerging trends in public health education, training needs, and employer support for continuing education. Results …

Ultraviolet Radiation Stimulates Expression Of Snail Family Transcription Factors In Keratinocytes. Hudson L, Choi C, Newkirk K, Parkhani J, Cooper K, Lu P, Kusewitt D, Kim M. Newkirk

Kim M Newkirk

No abstract provided.

Uveal Spindle Cell Tumor Of Blue-Eyed Dogs: An Immunohistochemical Study. Zarfoss M, Klauss G, Newkirk K, Kiupel M, Jones Y, Colitz C, Weisbrode S, Kusewitt D, Dubielzig R., Kim M. Newkirk

Kim M Newkirk

No abstract provided.

Snai2 Expression Enhances Uvr-Induced Skin Carcinogenesis. Newkirk K, Parent A, Fossey S, Choi C, Chandler H Rajala-Schultz P, Kusewitt D., Kim M. Newkirk

Kim M Newkirk

No abstract provided.

Ultraviolet Radiation Exposure Induces Corneal Degeneration In 129 Mice. Newkirk K, Chandler H, Parent A, Young D, Colitz C, Wilkie D, Kusewitt D, Kim M. Newkirk

Kim M Newkirk

No abstract provided.

Responsibility For Hiv Prevention: Patterns Of Attribution Among Hiv-Seropositive Gay And Bisexual Men, C. Offer, O. Grinstead, E. Goldstein, Edward M. Mamary, N. Alvarado, J. Euren, W. Woods

Edward M. Mamary

The article presents research based on narratives by gay and bisexual men recently infected with HIV. Researchers looked at the men's attributions of responsibility for infection, comparing recollections of feelings before becoming infected with views expressed after seroconversion. The research responds to a call to better understand risk behavior among HIV-positive persons, in an effort to craft effective prevention interventions. In both before-and after-HIV infection views, survey participants expressed a sense of personal responsibility. Researchers report also nuances of views about shared responsibility.

How Heel Oxygenation Changes Under Pressure, Vivian K. Wong, N. A. Stotts, H. W. Hopf, E. S. Froelicher, G. A. Dowling

Vivian K. Wong

The mechanism of heel pressure ulcers after hip surgery is not entirely understood. The purpose of this one-group, prospective, repeated-measures design study was to examine how the external pressure of the bed surface affects heel skin oxygen tension in adults on the first 3 days after hip surgery. Transcutaneous oxygen sensors were placed on the plantar surface of each foot, close to the heels. Measures were taken on room air and with an oxygen challenge with the heels (1) suspended above the bed surface (preload), (2) on the bed surface for 15 minutes (loading), and (3) again suspended above the …

Selecting For A Diverse Public Health Workforce - Community Health Education Mph Program For Admissi, Edward M. Mamary

Edward M. Mamary

The population of California continues to become more diverse; it has become increasingly important for California universities to provide graduate education to underrepresented groups and to prepare culturally competent health educators whose skills are adapted to these dynamic demographic changes. This paper describes the graduate admissions requirements of the four California-based graduate programs in Community Health Education (CHE) accredited by the Council on Education for Public Health (CEPH ) and uses the graduate admissions process at San Jose State University as a case example for selecting a cohort that reflects the cultural and linguistic diversity of the state. The use …

Physiology And Prevention Of Heel Ulcers: The State Of Science, Vivian K. Wong, N. A. Stotts

Vivian K. Wong

The prevalence of heel ulcers across settings is high and is increasing. Prevention of ulcers requires knowledge of their etiology and the scientific basis for preventive care. The interaction between external pressure and the heel vasculature is central to the prevention of heel ulcers. This article focuses on the prevention of heel pressure ulcers. The physiology of heel tissue perfusion, the effect of external pressure on heel perfusion, as well as what is known about strategies to reduce external pressure and approaches to improve heel skin blood flow will be discussed. It is only through understanding of the physiology of …