Medicine and Health Sciences Commons^™

Evaluation Of Common Complications Following Tetralogy Of Fallot Surgical Repair By Magnetic Resonance Imaging, Zainab Ahmad Ramadan, Mohamed Salah Ayyad

Mansoura Medical Journal

Background: The operative procedures for correction of tetralogy of Fallot (TOF) concentrates on the impact of pulmonary valve regurgitation (PR) on the function of right ventricle (RV) pointing to alleviating right ventricle outflow tract (RVOT) narrowing, and minimizing the PR degree at the same time, closing ventricular septal defect (VSD). Various complications could be encountered after TOF repair as; PR, dilated RV with/without impaired function, RVOT residual obstruction/ dilatation, residual VSD, tricuspid regurge (TR), aortic root dilatation with/without regurge and significant difference in differential pulmonary flow. Objective: Address the most common complications that could be encountered following TOF surgical repair, …

Study Of Serum Bilirubin In Relation To Stable Chronic Coronary Artery Disease Severity And Outcome After Percutaneous Intervention, Khaled E Mahfouz, Ahmed W Suliman, Mahmoud A Youssef, Adel M Osman

Mansoura Medical Journal

Background: Bilirubin is endogenous antioxidant and increased its physiological concentrations reduce severity of coronary artery disease with better prognosis after PCI. Objective: Assess serum bilirubin level in patients with stable chronic coronary artery disease and correlate it with the severity of this disease and outcome after PCI. Methods: Cross sectional prospective observational study included 203 Patient with stable chronic coronary artery disease divided into 2 groups according to bilirubin: group I ≤ 0.6mg/dl group II > 0.6 (up to 1.2) mg/dl 100 cases underwent elective coronary angiography and PCI with full clinical examination, laboratory tests: total serum bilirubin, creatinine, lipid profile, …

Association Between Serum Procalcitonin Level With Exacerbation Severity In Chronic Obstructive Pulmonary Disease Patients, Dalia Abdellateif Abdelghany, Shimaa R. Hendawy, Rania Mostafa, Heba Wagih Abdelwahab

Mansoura Medical Journal

Background: There is a significant impact on morbidity, mortality, and quality of life due to chronic obstructive pulmonary disease exacerbations. Individuals with acute exacerbation of chronic obstructive pulmonary disease had considerably higher mean serum procalcitonin levels (PCT) compared to individuals with stable chronic obstructive pulmonary disease, according to previous investigations. Objective: This study aimed to assess whether procalcitonin levels were associated with the severity of exacerbations in patients with chronic obstructive pulmonary disease. Methods: thirty-nine patients who were suffering from an acute exacerbation of chronic obstructive pulmonary disease were included. Included patients were classified as having either no respiratory failure, …

Timolol As A Migraine Acute Attack Therapy: Randomized, Otcs Control Study, Shimaa Elgamal, Hossam Egila, Ibrahim Kabbash, Hussien El-Ansarey, Mohamed Elshafie, Osama Elshafei

Mansoura Medical Journal

Background: Migraine is manifested by recurrent headache attacks, with variable characteristics and associated symptoms. Oral beta blockers are widely used to prevent and reduce the frequency these attacks. However, the use of topical beta blockers for acute treatment is still controversial. Aims: In this randomized double – armed study, we aim to compare the efficacy of Timolol 0.5% eyedrops compared to other over-the-counter (OTC) medications used for acute treatment of migraine. Methods: Fifty-seven patients were randomly allocated to group A (treatment group: Timolol 0.5% eyedrops), and group B (control group: OTC drugs including Non-steroidal anti-inflammatory drugs (NSAIDs), caffeine, aspirin, and …

Assessment Of Serum Levels Of Cxcl10 In Patients With Non-Segmental Vitiligo, Sara Khashaba, Mohammed Hussein Elmogy, Hanan Fathy Mohamed, Mohammad El-Nablaway, Ahmed Fawzi Ismael

Mansoura Medical Journal

Background: Vitiligo is the most common depigmenting skin disorder. Destruction of melanocytes result in depigmented skin lesions. Pathogenesis is not fully understood and mostly is multifactorial. However, the autoimmune theory is the most widely accepted one. The interaction between genetic, environmental, biochemical and immunologic factors contribute to the disease. Cytokines have an important role in development of the disease and its progression. Aim of the work: The aim of the present study is to measure the blood levels of C-X-C motif chemokine ligand 10 (CXCL10) in vitiligo and to correlate it with disease activity and severity. Methods: This is a …

Migraine Among Neurology Outpatient Attendants In Mansoura University: Sociodemographic And Migraine Comorbidities Analysis, Mohammad Youssif Ismail Ibrahim, Tamer Mohammad Belal, Hossam Mohammad Egila, Ahmed Gamal Azab

Mansoura Medical Journal

Background: Twelve percent of the population is thought to suffer from migraines. 1% to 2% of individuals worldwide suffer from chronic migraine (CM). Approximately 2.5% of cases who have episodic migraine (EM) develop CM. A number of risk factors are linked to the development of CM. Independent of medication; there is a sizable short-term variance in migraine frequency. Sleep difficulties, psychological illness, and cardiovascular disease are all linked to migraine. It is the second most incapacitating illness globally. Objectives: To evalaute the sociodemographic characteristics of migraineurs and their different co-morbidities. Patients and methods: A cross-sectional study with analytic component was …

Wheezy And Cough Asthma Phenotypes In A Cohort Of Egyptian Children: Clinical Features And Ccr3 T51c Gene Polymorphism, Magdy Mohamed Zedan, Mai Magdy Kera, Eman Omar Khashaba, Mona El Wassefy, Amal Mohamed Osman

Mansoura Medical Journal

Background: Asthma is a heterogenous disease with variable characteristic phenotypes. Correlating clinical asthma phenotypes with the underlying genotypes could pave the way for development of tailored asthma medications. Objective: The purpose of this study was to describe the clinical features of wheezy and cough asthma phenotypes and to assess the frequency of CCR3T51C gene polymorphism among Egyptian asthmatic children. Methods: A group of 60 Egyptian asthmatic children (40 wheezy phenotype and 20 cough phenotype) together with 100 controls were enrolled and analyzed for the genotypes of CCR3 T51C polymorphisms using PCR-RFLP. Serum IgE levels were determined by ELISA technique. Results: …

Value Of Qrs Fragmentation As Novel Electrocardiogram Predictor Of Reperfusion In Acute Myocardial Infarction Patient, Hoda M. Sobh, Nader E. Awad, Mohamed A. Omar

Mansoura Medical Journal

Background: The main target of treatment of STEMI is to restore coronary blood flow and maintain myocardial perfusion. Several tools including electrocardiographic and coronary angiographic parameters are used to assess myocardial reperfusion. Fragmented QRS is associated with increased adverse cardiovascular events, it was proved to bea marker of ventricular dysfunction and poor prognosis in STEMI. Aim of the work : To study the relation between QRS fragmentations and the degree of myocardial reperfusion in patients with STEMI treated with either fibrinolytic therapy or primary percutaneous coronary interventions (1ry PCI). Patients and methods: 100 subjects admitted with first attack of STEMI …

Association Of Vitamin D Receptor Cdx-2 Polymorphism With Covid-19: A Case-Control Study, Mahmoud M. Alseoudy, Maha O. Hammad, Mohmed Elgamal, Dalia A. Abdelghany, Asmaa M. Borg, Ahmed El-Mesery, Dina Elzeiny

Mansoura Medical Journal

Background: Host genetic variability has been suggested as an important explanation for inter-individual differences in COVID-19 susceptibility and severity. Most vitamin D actions in the regulation of immunity are mediated by vitamin D receptors (VDRs). Polymorphisms in the VDR gene have been associated with several health outcomes; however, their effects on COVID-19 still need more clarification. This study aims to investigate the association of the VDR SNP (rs11568820, Cdx-2) with susceptibility and inter-individual variability of the severity of COVID-19. Methods: A total of 100 confirmed COVID-19 patients and 100 age and sex-matched controls were enrolled in this study between July …

Spinal Cord Lipomas In Children: Surgical Resection And Outcome, Ramy Omar Omar El Sakhry, Hatem Ibrahim Badr, Ibrahim El Sayd Ahmed Abdel-Aal, Amr Farid Khalil

Mansoura Medical Journal

Background: management of spinal lipomas is considered a challenging task for pediatric neurosurgeons. Study Design: A prospective, clinical study. Objectives: To assess the neurological outcomes after surgical resection of spinal lipomas. Patients and methods: The study was performed on 30 patients, underwent surgical resection of spinal cord lipomas. The cases were followed up post-operatively in the outpatient clinic for at least 24 months. Results; This study included 30 patients with spinal lipomas (12 boys and 18 girls) with age of less than two years at surgery. At presentation, all the 30 cases had low back swelling.19 (63.3%) with bladder dysfunction, …

Potential Neuroprotective Effect Of Artemisinin In A Rotenone-Induced Mice Model Of Parkinson’S Disease, Nada M. Hamada, Hanan Eissa, Nirmeen Megahed, Mohamed H. Daba, Ahlam Elmasry

Mansoura Medical Journal

Background: Parkinson’s disease (PD) is characterized by motor dysfunctions including tremors, rigidity and bradykinesia. Medications for PD alleviate motor symptoms rather than targeting disease pathogenesis. Recently discovered features of artemisinin suggested that it might be used to treat neurodegenerative diseases. Objective: to explore the possible neuroprotective effect of artemisinin in different doses in a rotenone-induced model of PD. Materials & methods: Twenty-five mice were randomly divided into five groups: group 1; negative-control, group 2; positive-control, and groups 3&4&5: artemisinin-treated (30, 40 and 50 mg/kg) respectively. For PD induction, rotenone (3mg/Kg/day) was administered intraperitoneally for 42 days (6 weeks). Behavioral assessment …

The Prognostic Value Of Androgen Receptor And Cyclin D1 In Infiltrating Duct Carcinoma Of The Breast, Dina A Abd El-Ghaffar, Amal Af Halim, Eman A Abdallah, Doaa A Sharaf, Shaimaa M Yussif

Mansoura Medical Journal

Objective: Breast cancer (BC) tissue is heterogeneous with a number of cellular pathways involved in cell growth and proliferation. Activation of androgen receptors (AR) signaling pathways plays a role in BC. On the other hand, cyclin is a regulatory subunit of cyclin dependent kinases that affect cell cycle G1/S transition. This study aimed at investigating the relationship between the expression of AR and cyclin D1 and the clinicopathological details of BC patients registered in the archive of our department within a specified period and determining the prognostic impact of such expression.

Methods: The study included 182 IDC patients aged from …

Effectiveness Of Allergen Immunotherapy In Cigarette Smokers With Allergic Airway Disorders, Heba Wagih Abdelwahab, Mostafa Bakeer, Ahmed Mohamed Fouda

Mansoura Medical Journal

Background: Exposure to environmental tobacco smoke (ETS) is associated with several medical diseases especially allergy, but little is known about the effects of cigarette smoking on allergen immunotherapy response. Aim: This study aims to explore any association between cigarette smoking and response to allergen immunotherapy in patients with allergic airway disorders. Patients and methods: The study was conducted on patients with allergic airway disorders who received subcutaneous immunotherapy. All patients were assessed as regard smoking history including pack-year index and dependence, symptoms and medication scores. Patients’ demographic and clinical data were collected. A statistical analysis was then performed. Results: A …

Role Of Serum Ferritin And D-Dimer On Short Term Outcome In Acute Ischemic Stroke, Nourhan Ahmed Galal Sadek, Mohammed Mahmoud Abbas Ali, Yousra Mahmoud Amin Tera, Mohamed Abd-El-Salam Mohamed Ali

Mansoura Medical Journal

Background: Acute ischemic stroke (AIS) has been considered as a main reason of death globally. Currently, intervention could significantly enhance outcomes and reduce disability. Studies have been conducted to determine the factors that may have a role in the context of AIS prognosis formulation. Prognostic indicators, that has gained great clinical interest recently, are serum ferritin and D-dimer (DD). Aim: The aim of the current study was to assess the relation between serum levels of both ferritin and DD and severity of AIS at time of presentation and its relationship with the short-term outcome of patients. Methods: The present study …

Assessing The Activity Of Inflammatory Bowel Disease Using The Serum Marker: Neutrophil Gelatinase Associated Lipocalin (Ngal), Fatma Abozeid, Karim Ali, Mounir Bahgat, Maha Maher, Asmaa M. Borg

Mansoura Medical Journal

Background: IBD, or inflammatory bowel disease, is an active and remitting illness. One of the most overexpressed genes in the colonic mucosa of patients with ulcerative colitis (UC) and Crohn's disease (CD) is lipocalin 2, the coding gene of neutrophil gelatinase associated lipocalin (NGAL). We investigated NGAL's applicability in assessing IBD activity. Methods: This study was a single center case control type. Thirty of the sixty IBD patients who participated in the study were in remission, and thirty were in active disease. Twenty-eight healthy controls were included. Enrolled were patients with CD or UC. The control group and all patients …

Developing A Computer-Based Program For Language Rehabilitation Of Arabic-Speaking Aphasic Patients, Sara Elsherbeny, Ayman Amer, Hemmat Baz, Tamer Abou-Elsaad

Mansoura Medical Journal

Background: Aphasia is acquired selective impairment of language. Computerized aphasia therapy is useful in language therapy and offers chances for independent practice at home to maximize intensity and improve outcomes. The aim of this study was to develop a computer-based language rehabilitation program for Arabic-speaking Egyptian aphasic patients to be culturally, linguistically and socially suitable for them and to determine its effectiveness. Methods: We conducted a prospective interventional study on 20 aphasic patients in the age range 40-65 years who received rehabilitation for 3 months using a newly designed Arabic software program named “Takalam”. The program was pilot-studied on 10 …

Evaluation Of Cxcl2 And Autophagy Genes Expression In Rheumatoid Arthritis Patients And Its Relation To Cardiovascular Diseases, Mona Elhelaly, Dalia Kamal Nassar, Mohammed Kamal Nassar, Khaled Tarek Abdelalim, Samar Tharwat

Mansoura Medical Journal

Background Cardiovascular disease (CVD) is among the most common comorbidity and the leading cause of mortality in rheumatoid arthritis (RA) patients. The aim of this study was to assess at the levels of CXCL2 and autophagy genes such LC3 and Beclin 1 in RA patients and how they relate to the clinical manifestations and carotid intimal medial thickness. Methods This cross-sectional study included RA patients. Sociodemographic characteristics, clinical and therapeutic data were recorded. Thorough medical and clinical examination was conducted to evaluate the disease status including the number of swollen and tender joints, visual analogue scale and disease activity score …

Long-Term Stability Of Electrical Stapedial Reflex And Electrodes Impedance In Children With Med-El Cochlear Implants, Maram Mohamed Rashad Ghoniem, Ayman El-Saeed Elsharabasy, Yousef Kamel Shabana, Elshahat Ibrahem Ismail

Mansoura Medical Journal

Background

The purpose of this study was to investigate changes in electrical evoked stapedial reflex thresholds (ESRTs) and electrodes impedance over time in children with MED-EL cochlear implants.

Methods

In this study, 60 kids were included, while 15 kids were excluded because their cases did not fit the requirements. Patients who received MED-EL cochlear implants were monitored postoperatively over 5 years to determine whether or not their ESRT and electrode impedance remained stable.

Results

At the initial fitting, electrodes 4, 5, 6, 8, and 9 showed significantly different impedances, while electrodes 1, 2, 3, 7, 10, 11, and 12 showed …

One Stage Procedure Versus Two Stages Procedure In Management Of Obstructed Non-Perforated Cancer Colon, Magdy Basheer, Mahmoud Neamatallah, Ashraf Abbas, Mohamed Shetiwy

Mansoura Medical Journal

Background: The surgical management of large bowel emergency patients remains controversial. However, there has been an increasing trend toward primary reconstructive surgery. Objective: To evaluate one-stage procedure versus two-stage procedure in cases presented with obstructed nonperforated cancer colon in terms of operative time, hospital stay, postoperative complications, peri-operative mortality, and quality of life. Patients and methods: A prospective randomized study was conducted at Emergency Mansoura University Hospitals. A total of 50 cases diagnosed with obstructed nonperforated cancer colon were randomly allocated into two groups; the first group included 25 cases who underwent the one-stage approach, and the second one included …

The Effect Of Hepatitis C Virus Infection On Ovarian Reserve, Khaled Mahmoud Ahmed Amin Abdo, Mahmoud Mohamed Abdelrazik, Eman Salah Eldin Mohamed Fadel, Ashraf Ahmed Foda, Mohamed Abd Ellatif Elnegeri

Mansoura Medical Journal

Background: Hepatitis C has the highest frequency in Egypt, with 14.7 percent of the population affected between the ages of 15 and 49, according to the World Health Organization. Hepatitis C virus antibodies have been detected in 12.2% of women and 17.4% of men. Patients and Methods: This research was carried out in Mansoura University Hospital, Mansoura, Egypt. All participants (90 cases) in this study provided written informed consent to participate and were separated into 2 groups, the first group (group A) & the second group (group B). Women in group A (45 cases) were hepatitis C virus antibodies tested …

Outcome Of Covid-19 In Patients With Rheumatic Diseases Treated With Immunosuppressive Drugs, Ali Sobh, Noha Hazem Elnagdy, Mohamed Elegezy, Mohamed Mofreh, Mohamed Tohlob, Ahmad M. Eita, Ragheed Rizk, Ola Eliwa, Marwa H. Elnagdy, Ahmed Elsaeed Abdulgalil

Mansoura Medical Journal

Background: Rheumatologic disorders have been significantly impacted by the coronavirus disease 2019 (COVID-19) pandemic. The potential role of immunosuppressive drugs in the presentation, severity and even management of COVID-19 is still questionable. The aim of this work was to study the effect of immunosuppressive drugs on outcome of COVID-19 infection in patients with rheumatic diseases. 109 rheumatic patients (37 pediatrics and 72 adults) taking immunosuppressive treatment with confirmed COVID-19 infection were included in this study. Clinical, laboratory, radiological findings and outcome of these patients were retrospectively retrieved from hospital medical records. Results: The majority of adult cases were rheumatoid arthritis …

Impact Of Covid - 19 Pandemic On The Clinical Course Of Inflammatory Bowel Disease In Egyptian Tertiary Centers, Alaa Alsawak, Omar Abdallah, Ali Madian, Hassan Atalla, Ramadan Eldamarawy, Ahmed Eliwa, Ahmed Khamiss, Ashraf El Sharkawy, Sadek Mostafa, Alshimaa Alaboudy, Maha M. Maher, Ashraf Elbahrawy

Mansoura Medical Journal

Abstract

Background/Aim: The coronavirus disease 2019 (Covid-19) pandemic have a major impact on the clinical course of chronic diseases including inflammatory bowel disease (IBD). In the current study we aimed to evaluate the clinical relapse and worsening of IBD activity during Covid-19 pandemic.

Methods: 125 patients included and followed for one year. Of them, 98 and 27 patients had inactive and active IBD before the study, respectively. The clinical activity of IBD assessed by Crohn’s disease activity index (CDAI) and simplified colitis clinical activity index (SCCAI). Severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) infection detected by real-time polymerase chain …

Screening For Obstructive Sleep Apnea In A Sample Of Egyptian Idiopathic Intracranial Hypertension Female Patients Using The Berlin Questionnaire, Nada Elsaid, Ahmed A.H. Mosa, Ahmed Saied

Mansoura Medical Journal

Background: Obstructive sleep apnea (OSA) is one of the risk factors of idiopathic intracranial hypertension (IIH). The Berlin questionnaire (BQ) is a validated reliable method for identification of increased likelihood of OSA. We aimed to screen a sample of female IIH patients for OSA using the BQ. Methods: This study included 40 females; 20 newly diagnosed IIH patients and 20 healthy control subjects. The BQ was obtained from all of the study participants and it was divided into high or low risk for OSA. Results: The patient and control cohorts were age matched. The BMI was significantly higher in the …

Assessment Of Hypothyroidism Among Adult Patients Suffering From Beta Thalassemia Major, Ahmed Saleh Ibrahim, Azza Hasan Abd El-Fatah, Ayman Fathy Abd El-Halim, Fared Fawzy Mohamed

Mansoura Medical Journal

Background: Although beta thalassemia major (BTM) patients are properly treated with blood transfusions in accompany with iron chelation therapy, they suffer from serious complications such as hypothyroidism. Aim: This work aims to assess hypothyroidism among adult with β-thalassemia major patients and to find out its association with various parameters such as age, body mass index (BMI) ,gender ,hemoglobin(Hb) and serum ferritin levels. Methods: This cross-sectional study included 200 adult BTM patients (males 115 and females 85 ; mean age 24.684 ±5.30761 years; ranging from 18 to 43 years old). Statistical data analysis was performed using IBM-SPSS software package version 26.0. …

Total Serum Immunoglobulin E In Patients With Psoriasis Vulgaris, Sara A. Gooda

Mansoura Medical Journal

Introduction Psoriasis vulgaris (PV) is a multifactorial disease in which some environmental factors acting on people who have a particular genetic predisposition trigger immune dysregulation and irregular keratinization, inducing typical cutaneous lesions. Serum IgE levels are low in normal subjects, on the other hand they increase in atopy, parasitic infestation, and particular forms of malignant tumours. The aim of this study was to assess serum levels of total IgE in cases with PV. Methods This research was a case-control study and comprised 40 psoriasis cases and matched age and sex 40 healthy subjects. Complete general and dermatological examination comprised a …

Evaluation Of Platelet Indices And Low-Density Lipoprotein (Ldl) As Predictors Of Acute Ischemic Stroke Severity And Outcome, Ahmed E. Al-Sharabi, Ashraf A. El-Mitwalli, Yousra M. Tera, Hossam M. Egila

Mansoura Medical Journal

Background: Platelets play a role in atherosclerosis, inflammation, and thrombosis. Prothrombotic events, activation, aggregation, and adhesion are all increased by elevated mean platelet volume (MPV) and platelet distribution width (PDW) levels; high low-density lipoprotein (LDL) raises the risk of cardiovascular disease. Aims: Investigate the association between platelet indices, lipid profile, stroke severity, and outcome in patients with acute ischemic stroke. ‎ Subjects and methods: A prospective case-control study involved 100 acute ischemic stroke patients and 100 controls from Mansoura University Hospitals. Patients underwent neurological assessments, including the National Institutes of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS), and Alberta …

Assessment Of Serum Lipoprotein Phospholipase A2 As An Atherosclerotic Risk Factor In Ischemic Stroke Elderly Patients, Amr Ragab Yousef Ismael, Ahmed Saied, Ahmed Mohamed Elewa, Mohamed Said Gomaa

Mansoura Medical Journal

Background Significant evidence does exist regarding the significant role of inflammation in the development of atherosclerosis. Lipoprotein phospholipase A2 is a phospholipase A2 enzyme (Lp-PLA2) which is predominantly produced by macrophages and lymphocytes in atherosclerotic plaque. Increased Lp-PLA2 concentrations are significantly linked to atherosclerosis-related diseases which include cardiovascular diseases and ischaemic strokes. Aim This study was conducted to assess the role of serum level of Lp-PLA2 in cerebral atherosclerosis. Methods This prospective cross-sectional case-control study enrolled 100 patients aged 60 years old or more with acute ischaemic stroke (AIS). Using the TOAST classification, patients were divided into case group "atherosclerotic” …

Don’T Miss What Is Hidden On Cardiac Ct Angiography: Extra-Cardiac Findings Count, Zainab Ahmad Ramadan, Aya Ahmed Elboghdady, Aya Mohammed Abdel Aziz, Farah Ahmed Shokeir

Mansoura Medical Journal

Background: Multi-detector computed tomography (MDCT)is the main imaging modality in cardiovascular diseases. Another important role of MDCT is assessment of extra-cardiac structures outside the pericardium. These extra-cardiac findings may be of great relevance. Methods: Cardiac MDCT scan results were retrospectively reviewed by radiologist for the presence of extra-cardiac findings between February 2020 and December 2022. They were categorized according to anatomical location into systems as pulmonary, pleural, mediastinal, bronchial, vascular, bony, abdominal and miscellaneous. Results: A total of 955 patients had a cardiac multidetector CT angiography scan during the study period. Extra-cardiac findings were reported in 320 (33.5%) of these …

Myocardial And Renal Protective Effects Of Dexmedetomidine Vs Magnesium Sulphate In Patients Undergoing Elective Open Abdominal Aortic Surgery, Mohamed Younes Yousef Abd Allah, Maha Younes Youssef Abd-Allah, Abdelrahman Mohammed Elnagar

Mansoura Medical Journal

Background: After abdominal aortic aneurysm surgery, the likelihood of postoperative myocardial infarction is seven percent, but likelihood of postoperative cardiac problems without signs of ischemic damage is thirty-six percent. Aim: goal of research had been to assess perioperative myocardial protective impact of dexmedetomidine and magnesium sulphate in high‑risk studied cases undergoing aortic vascular surgery. Methods: This randomized double blinded research had been being done in cardiothoracic & vascular surgery center, Mansoura university from May 2023 to October 2023 after approval from institutional review board of faculty of Medicine Mansoura University with obtaining a written informed consent from all studied cases. …

Unusual Late Presentation Of Kartagener Syndrome: A Case Report, Abdulhadi H. Al-Mazroea

Mansoura Medical Journal

Kartagener's syndrome (KS) is a rare inherited autosomal recessive condition. It comprises of the triad chronic sinusitis, bronchiectasis, and situs inversus. The symptoms are more prevalent in children in the early years of life. We describe a case of a 15-year-old child showing severe respiratory distress with a history of intermittent wet cough and rhinitis for the past six months. The patient was diagnosed with dextrocardia at birth and had no significant medical history since then. Based on his clinical presentation and imaging findings, he was diagnosed with KS that was confirmed by whole-exome sequencing. The patient was managed with …