Medicine and Health Sciences Commons^™

Fixing A Hole: A Retrospective Cohort Study Evaluating Hav, Hbv, Tetanus Screening, And Vaccination During Hospitalization In Persons Who Use Substances, Amber C. Streifel, Jose Eduardo Rivera Sarti, Monica K. Sikka, Michael Conte, Bradie Winders, Cara D. Varley

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background:Rates of serious injection-related infections in persons who use drugs have increased. Resulting admissions are an opportunity for screening and vaccination of preventable infections such as hepatitis A virus (HAV), hepatitis B virus (HBV), and tetanus. Design and methods:We conducted a retrospective review of adults with documented substance use admitted for bacterial infection between July 2015 and March 2020. We evaluated HAV, HBV, and tetanus vaccination status at admission, along with screening for HAV and HBV infection and immunity. We identified the proportion of patients at risk for infection who received HAV, HBV, and tetanus vaccines during admission and patient-level …

Amelioration Of Age-Related Cognitive Decline And Anxiety In Mice By Centella Asiatica Extract Varies By Sex, Dose And Mode Of Administration, Nora E. Gray, Wyatt Hack, Mikah S. Brandes, Jonathan A. Zweig, Liping Yang, Luke Marney, Jaewoo Choi, Armando Alcazar Magana, Natasha Cerruti, Janis Mcferrin, Seiji Koike, Thuan Nguyen, Jacob Raber, Joseph F. Quinn, Claudia S. Maier, Amala Soumyanath

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: A water extract (CAW) of the Ayurvedic plant Centella asiatica administered in drinking water has been shown to improve cognitive deficits in mouse models of aging and neurodegenerative diseases. Here the effects of CAW administered in drinking water or the diet on cognition, measures of anxiety and depression-like behavior in healthy aged mice are compared.Methods: Three- and eighteen-month-old male and female C57BL6 mice were administered rodent AIN-93M diet containing CAW (0, 0.2, 0.5 or 1% w/w) to provide 0, 200 mg/kg/d, 500 mg/kg/d or 1,000 mg/kg/d CAW for a total of 5 weeks. An additional group of eighteen-month-old mice …

Impact Of Sars-Cov-2 Infection On Long-Term Depression Symptoms Among Veterans., Jason I. Chen, David Bui, Theodore J. Iwashyna, Troy A. Shahoumian, Alex Hickok, Megan Shepherd-Banigan, Eric J. Hawkins, Jennifer Naylor, Diana J. Govier, Thomas F. Osborne, Valerie A. Smith, C Barrett Bowling, Edward J. Boyko, George N. Ioannou, Matthew L. Maciejewski, Ann M. O'Hare, Elizabeth M. Viglianti, Amy S-B Bohnert, Denise M. Hynes

OHSU-PSU School of Public Health Faculty Publications and Presentations

Prior research demonstrates that SARS-COV-2 infection can be associated with a broad range of mental health outcomes including depression symptoms. Veterans, in particular, may be at elevated risk of increased depression following SARS-COV-2 infection given their high rates of pre-existing mental and physical health comorbidities. However, few studies have tried to isolate SARS-COV-2 infection associations with long term, patient-reported depression symptoms from other factors (e.g., physical health comorbidities, pandemic-related stress).

Concordance Between Two Monoclonal Antibody-Based Antigen Detection Enzyme-Linked Immunosorbent Assays For Measuring Cysticercal Antigen Levels In Sera From Pigs Experimentally Infected With Taenia Solium And Taenia Hydatigena, Gianfranco Arroyo, Luz Toribio, Sara Garrido, Nancy Chile, Teresa Lopez-Urbina, Luis A. Gomez-Puerta, Miguel Muro, Robert H. Gilman, Yesenia Castillo, Pierre Dorny, Seth E. O’Neal, Armando E. Gonzalez, Hector H. Garcia, For The Cysticercosis Working Group In Peru (Cwgp)

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: Antigen detection in Taenia solium cysticercosis confirms viable infection in the intermediate host (either pig or human). The reference B158/B60 monoclonal antibody (mAb)-based Ag-enzyme-linked immunosorbent assay (ELISA) has acceptable levels of sensitivity and specificity in human neurocysticercosis with multiple brain cysts, although its sensitivity is lower in cases with single brain cysts, whereas in porcine cysticercosis the assay specificity is affected by its frequent cross-reaction with Taenia hydatigena, another common cestode found in pigs. Our group has produced 21 anti-T. solium mAbs reacting against antigens of the whole cyst, vesicular fluid, and secretory/excretory products, identifying TsW8/TsW5 as the most …

Contralateral Second Dose Improves Antibody Responses To A 2-Dose Mrna Vaccination Regimen, Sedigheh Fazli, Archana Thomas, Abram E. Estrada, Hiro A. P. Ross, David Xthona Lee, Steven Kazmierczak, Mark K. Slifka, David Montefiori, William B. Messer, Marcel E. Curlin

OHSU-PSU School of Public Health Faculty Publications and Presentations

BACKGROUND. Vaccination is typically administered without regard to site of prior vaccination, but this factor may substantially affect downstream immune responses. METHODS. We assessed serological responses to initial COVID-19 vaccination in baseline seronegative adults who received second-dose boosters in the ipsilateral or contralateral arm relative to initial vaccination. We measured serum SARSCoV-2 spike–specific Ig, receptor-binding domain–specific (RBD-specific) IgG, SARS-CoV-2 nucleocapsid–specific IgG, and neutralizing antibody titers against SARS-CoV-2.D614G (early strain) and SARS-CoV-2.B.1.1.529 (Omicron) at approximately 0.6, 8, and 14 months after boosting. RESULTS. In 947 individuals, contralateral boosting was associated with higher spike-specific serum Ig, and this effect increased over time, …

What Adolescents Say In Text Messages To Motivate Peer Networks To Access Health Care And Sexually Transmitted Infection Testing: Qualitative Thematic Analysis, Marguerita Lightfoot, Chadwick Campbell, Allysha C. Maragh-Bass, Joi Jackson-Morgan, Kelly Taylor

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background:While rates of HIV and sexually transmitted infections (STIs) are extremely high among adolescents and young adults in the United States, rates of HIV and STI testing remain low. Given the ubiquity of mobile phones and the saliency of peers for youths, text messaging strategies may successfully promote HIV or STI testing among youths.

Objective:This study aimed to understand the types of messages youths believe were motivating and persuasive when asked to text friends to encourage them to seek HIV or STI testing services at a neighborhood clinic.

Methods:We implemented an adolescent peer-based text messaging intervention to encourage clinic attendance …

Primary Care As A Protective Factor: A Vision To Transform Health Care Delivery And Overcome Disparities In Health, Edward L. Machtinger, Alicia F. Lieberman, Christina D. Bethell, Marguerita Lightfoot

OHSU-PSU School of Public Health Faculty Publications and Presentations

A large body of research demonstrates that experiences of trauma, especially when they occur in the absence of safe, stable, nurturing relationships (SSNRs) and environments— known as protective factors— interrupt healthy development and predispose both children and adults to the most common causes of physical and mental illness and early death.1,2 Because minoritized and low-income populations are exposed to more trauma and have access to fewer protective factors, they experience higher rates of trauma-related health and social problems and severe disparities in health.1–4 Primary care clinicians increasingly recognize the role that trauma plays in the health and well-being of their …

Patient And Caregiver Perspectives On Implementation Of Ace Screening In Pediatric Care Settings: A Qualitative Evaluation, Ingrid Estrada-Darley, Peggy Chen, Ryan Mcbain, Gabriela Alvarado, Charles Engel, Nipher Mallika, Edward L. Machtinger, Brigid Mccaw, Marguerita Lightfoot, Multiple Additional Athors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Introduction

This qualitative research study explored the perspectives of adolescents, 12 to 19-years-old, and caregivers of children under 12-years-old on the acceptibility of adverse childhood experiences (ACEs) screenings in five pediatric clinics.

Method

A constructivist grounded theory approach was utilized. One-on-one semistructured phone interviews were conducted with 44 adolescents and 95 caregivers of children less than 12 years old. Interviews were analyzed using thematic analysis.

Results

Most participants reported feeling comfortable discussing ACEs with their providers. Some reported that screening helped build trust. Others expressed privacy concerns and did not receive information about the reason for screening. Adolescent patients …

The Feasibility, Acceptability, And Preliminary Impact Of Real-Time Monitors And Sms On Tuberculosis Medication Adherence In Southwestern Uganda:Findings From A Mixed Methods Pilot Randomized Controlled Trial, Angella Musiimenta, Wilson Tumuhimbise, Esther Atukunda, Aaron T. Mugaba, Nicholas Musinguzi, David Bangsberg, J. Lucian Davis, Conrad Muzoora, Jessica E. Haberer

OHSU-PSU School of Public Health Faculty Publications and Presentations

We conducted a pilot randomized controlled trial among patients initiating treatment for drug-sensitive tuberculosis (TB). Participants received real-time electronic adherence monitors and were randomized (1:1:1) to: (i) daily SMS (reminders to TB patients and notifications to social supporters sent daily for 3 months, then triggered by late or missed dosing for 3 months); (ii) weekly SMS (reminders to TB patients and notifications to social supporters sent weekly for 3 months, then triggered by late or missed dosing for 3 months); or (iii) control (no SMS). Feasibility was mainly verified by the technical function of the intervention at Month 6. The …

Antibody Banding Patterns On The Enzyme-Linked Immunoelectrotransfer Blot (Eitb) Assay Clearly Discriminate Viable Cysticercosis In Naturally Infected Pigs, Gianfranco Arroyo, Andrés G. Lescano, Cesar M. Gavidia, Maria Teresa Lopez-Urbina, Miguel Ara-Gomez, Lucho Gomez-Puerta, Seth E. O’Neal, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Enzyme-linked immunoelectrotransfer blot (EITB) detects antibodies against seven Taenia solium larvae antigens in three protein families (GP50, T24/42, and 8-kDa) with different structures and functions. EITB banding patterns against these antigens in pigs provide information about the course of infection and may discriminate viable cysticercosis. We analyzed the banding patterns and infection outcomes (presence of viable cysts, degenerated cysts, and any cysts) of 512 rural pigs. Banding patterns were grouped into homogenous classes using latent class analysis, and relationships with infection outcomes were assessed. Four classes were identified: 1 (n = 308, EITB-negative or positive for the GP50 family), 2 …

Spatial Transferability Of An Agent‑Based Model To Simulate Taenia Solium Control Interventions, Francesco Pizzitutti, Gabrielle Bonnet, Eloy Gonzales-Gustavson, William K. Pan, Hector H. Garcia, Armando E. Gonzalez, Seth E. O’Neal, Sarah Gabriël, Cysticercosis Working Group Peru

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background

Models can be used to study and predict the impact of interventions aimed at controlling the spread of infectious agents, such as Taenia solium, a zoonotic parasite whose larval stage causes epilepsy and economic loss in many rural areas of the developing nations. To enhance the credibility of model estimates, calibration against observed data is necessary. However, this process may lead to a paradoxical dependence of model parameters on location-specific data, thus limiting the model’s geographic transferability.

Methods

In this study, we adopted a non-local model calibration approach to assess whether it can improve the spatial transferability of …

Awareness Of The Public Charge, Confidence In Knowledge, And The Use Of Public Healthcare Programs Among Mexican-Origin Oregon Latino/As, Edlyn Wolwowicz-Lopez, Emily Boniface, Sara Díaz-Anaya, Yareli Cornejo-Torres, Blair Darney

OHSU-PSU School of Public Health Faculty Publications and Presentations

Objective We describe awareness about the modified “public charge” rule among Oregon’s Mexican-origin Latino/a population and whether concerns about the rule influenced disenrollment from state-funded programs, which do not fall under the public charge. Methods We conducted a cross-sectional survey of adults (ages 18–59) recruited at the Mexican consulate and living in the state of Oregon. Our outcomes were awareness (of the public charge, source of knowledge, and confidence in knowledge of the public charge) and disenrolling self or family members from state-funded public healthcare programs due to concerns about the rule. We described outcomes and used logistic regression and …

Respecting Tribal Voices In The Development Of A Gestational Diabetes Risk Reduction Preconception Counseling Program For American Indian/Alaska Native Adolescent Females: A Qualitative Study, Kelly R. Moore, Sarah Stotz, Martha Ann Terry, Ellen Seely, Kelly Gonzales, Gale Marshall, Jay Nadeau, Aletha Akers, Yesenia Garcia-Reyes, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background American Indians and Alaska Natives (AI/AN) are disproportionately affected by adolescent obesity, adolescent pregnancy and gestational diabetes mellitus (GDM). GDM is associated with increased risk for perinatal death, obesity, and subsequent type 2 diabetes (T2D) for the offspring. Moreover, mothers with GDM are also at increased risk for T2D post-partum. Yet few lifestyle interventions exist to reduce GDM risk prior to pregnancy. We describe the process of adapting an existing validated preconception counseling intervention for AI/AN adolescent girls at-risk for GDM and their mothers. Perspectives and recommendations were gathered from a diverse array of stakeholders to assure the new …

Musculoskeletal Pain, A Possible Indicator Of Central Sensitization, Is Positively Associated With Lower Urinary Tract Symptom Progression In Community-Dwelling Older Men, Angela Senders, Scott Bauer, Yiyi Chen, Barry Oken, Howard A. Fink, Nancy E. Lane, Kamran P. Sajadi, Lynn M. Marshall

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background

Musculoskeletal pain, a possible marker of central sensitization, is associated with higher prevalence of lower urinary tract symptoms (LUTS) among older men. We investigated whether musculoskeletal pain is associated with LUTS progression.

Methods

Participants were 5 569 men age ≥65 years enrolled in the prospective, multicenter Osteoporotic Fractures in Men (MrOS) Study. Self-reported musculoskeletal pain within 12 months before baseline was categorized as any pain and multilocation pain. Pain interference within 4 weeks of baseline was assessed with the SF-12 questionnaire. LUTS were assessed repeatedly with the American Urological Association Symptom Index (AUA-SI). Men with severe LUTS at baseline …

Melanoma Literacy Among The General Population Of Three Western Us States, Sancy A. Leachman, Elizabeth Stoos, Brian Detweiler-Bedell, Jerusha B. Detweiler-Bedell, Adrienne Zell, Elizabeth Wenzel, Emile Latour, Jack T. Wiedrick, Jodi Lapidus, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Melanoma is a significant cause of cancer death, despite being detectable without specialized or invasive technologies. Understanding barriers to preventive behaviors such as skin self-examination (SSE) could help to define interventions for increasing the frequency of early detection. To determine melanoma knowledge and beliefs across three high-incidence US states, 15,000 surveys were sent to a population-representative sample. We aimed to assess (1) melanoma literacy (i.e., knowledge about melanoma risks, attitudes, and preventive behaviors) and (2) self-reported SSE and its association with melanoma literacy, self-efficacy, and belief in the benefits of SSE. Of 2326 respondents, only 21.2% provided responses indicating high …

Multidrug Resistance Of Escherichia Coli From Outpatient Uncomplicated Urinary Tract Infections In A Large United States Integrated Healthcare Organization, Katia J. Bruxvoort, Jennifer H. Ku, S. Bianca Salas, Cara D. Varley, Joan A. Casey, Eva Raphael, Sarah C. Robinson, Keeve E. Nachman, Bruno J. Lewin, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background

Urinary tract infections (UTIs) cause significant disease and economic burden. Uncomplicated UTIs (uUTIs) occur in otherwise healthy individuals without underlying structural abnormalities, with uropathogenic Escherichia coli (UPEC) accounting for 80% of cases. With recent transitions in healthcare toward virtual visits, data on multidrug resistance (MDR) (resistant to ≥3 antibiotic classes) by care setting are needed to inform empiric treatment decision making.

Methods

We evaluated UPEC resistance over time by care setting (in-person vs virtual), in adults who received outpatient care for uUTI at Kaiser Permanente Southern California between January 2016 and December 2021.

Results

We included 174 185 individuals …

Racial/Ethnic And Gender Inequities In The Sufficiency Of Paid Leave During The Covid‐19 Pandemic: Evidence From The Service Sector, Julia M. Goodman, Daniel Schneider

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: Access to paid family and medical leave (PFML), including leave to care for a seriously ill loved one or recover from one's own serious illness, conveys health and economic benefits for workers and their families. However, without a national PFML policy, access to paid leave remains limited and unequal. Previous work documenting inequitable access by socioeconomic status and race/ethnicity primarily focuses on parental leave, measures theoretical access to paid leave rather than actual leave uptake, and lacks an accounting for why workers of color and women may have less access to PFML. We extend this literature by looking at …

Optic Nerve Head Gene Transcription Sequelae To A Single Elevated Iop Exposure Provides Insights Into Known Responses To Chronically Elevated Iop, Diana C. Lozano, Hari Jayaram, William O. Cepurna, Shandiz Tehrani, Lina Gao, Suzanne S. Fei, Dongseok Choi, Elaine C. Johnson, John C. Morrison

OHSU-PSU School of Public Health Faculty Publications and Presentations

Purpose: To clarify the optic nerve head (ONH) gene expression responses associated with a single, axon-damaging exposure to elevated IOP in relation to the composite cellular events previously identified in models of chronically elevated IOP.

Methods: Anesthetized rats were exposed unilaterally to an 8-hour pulse-train controlled elevation of IOP (PT-CEI) at 60 mm Hg, while others received normotensive CEI at 20 mm Hg. ONH RNA was harvested at 0 hours and 1, 2, 3, 7, and 10 days after either CEI and from naïve animals. RNA sequencing was performed to analyze ONH gene expression. DAVID Bioinformatics tools were used to …

Positive And Negative Experiences With Supportive Services And Programming: Gaps And Recommendations From Youth Experiencing Homelessness, Judy Y. Tan, G. Allen Ratliff, Ilsa Lund, Sherilyn Adams, Colette Auerswald, Marguerita Lightfoot

OHSU-PSU School of Public Health Faculty Publications and Presentations

Services for youth experiencing homelessness (YEH) are designed with limited input from the youth themselves. This study explored the experiences and recommendations for services aimed at mitigating the negative effects of homelessness among youth. A total of 45 interviews were conducted with YEH (ages 15 to 24, M = 21.5 years) who experienced at least one night of homelessness. Transcripts were coded by using a modified constructivist grounded theory approach. YEH reported myriad challenges to navigating disjointed programming and misguided policies. Recommendations from YEH for policy and programmatic change include peacekeeping and diffusion training for program staff, trauma-informed approaches, and …

Z60.5/(En)Coded, Ryan Petteway

OHSU-PSU School of Public Health Faculty Publications and Presentations

No abstract provided.

Final (Year 2) Report To Oha On Sogi Demographic Standards For Minors, Martin Arrigotti, Nell Carpenter, Kieran Chase, Alysia Cox, Itai Jeffries, Alexis Dinno

OHSU-PSU School of Public Health Faculty Publications and Presentations

Executive Summary

The report synthesizes thoughtful recommendations of the authors to the Oregon Health Authority (OHA) about routine data collection of SOGI† (sex, sexual orientation, and gender) demographic data in minors for clinical and reporting purposes. We see five primary motivations to routinely collect SOGI data, including to:

1. create an inclusive practice in order to welcome and make space for people from historically excluded genders, sexes, and sexual orientations,
2. promote health equity between minority and majority SOGI identities,
3. direct group-specific services towards those who need them,
4. represent the actual diversity of Oregon, and its communities, and
5. shift normative expectations about …

Community Paramedicine In Central Oregon: A Promising Model To Reduce Non-Urgent Emergency Department Utilization Among Medically Complexmedicaid Beneficiaries, Jessica Currier, Neal Wallace, Keshia Bigler, Maggie O’Connor, Paige E. Farris, Jackilen Shannon

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background

Community paramedicine has emerged as a promising model to redirect persons with nonmedically emergent conditions to more appropriate and less expensive community-based health care settings. Outreach through community paramedicine to patients with a history of high hospital emergency department (ED) use and chronic health conditions has been found to reduce ED use. This study examined the effect of community paramedicine implemented in 2 rural counties in reducing nonemergent ED use among a sample of Medicaid beneficiaries with complex medical conditions and a history of high ED utilization.

Methods

A cluster randomized trial approach with a stepped wedge design was …

"I'M Clean And Sober, But Not Necessarily Free": Perceptions Of Buprenorphine Among Patients In Long-Term Treatment, Jessica J. Wyse, Travis I. Lovejoy, Adam J. Gordon, Katherine Mackey, Anders Herreid-O'Neill, Benjamin J. Morasco

OHSU-PSU School of Public Health Faculty Publications and Presentations

Patients receiving buprenorphine for the treatment of opioid use disorder (OUD) experience a roughly 50% reduction in mortality risk relative to those not receiving medication. Longer periods of treatment are also associated with improved clinical outcomes. Despite this, patients often express desires to discontinue treatment and some view taper as treatment success. Little is known about the beliefs and medication perspectives of patients engaged in long-term buprenorphine treatment that may underlie motivations to discontinue.

Maternal Adverse Childhood Experiences, Child Mental Health, And The Mediating Effect Of Maternal Depression: A Cross-Sectional, Population-Based Study In Rural, Southwestern Uganda, Christine E. Cooper-Vince, Bernard Kakuhikire, Charles Baguma, Justin D. Rasmussen, David Bangsberg, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Objectives

This study aimed to examine the intergenerational effects of maternal adverse childhood experiences (ACEs) and child mental health outcomes in rural Uganda, as well as the potentially mediating role of maternal depression in this pathway. Additionally, we sought to test the extent to which maternal social group membership attenuated the mediating effect of maternal depression on child mental health.

Methods

Data come from a population-based cohort of families living in the Nyakabare Parish, a rural district in southwestern Uganda. Between 2016 and 2018, mothers completed surveys about childhood adversity, depressive symptoms, social group membership, and their children's mental health. …

Expanding On The Solutions To Reduce Neonatal Intensive Care Unit Morbidity And Mortality For Extremely Premature Infants—Looking Out The Hospital Window And Into The Neighborhoods, Christina Jäderholm, Lynne C. Messer

OHSU-PSU School of Public Health Faculty Publications and Presentations

The study from Sullivan et al1 is a valuable contribution to the literature that aims to improve health equity among very preterm infants (and their families). It is to be lauded for its attention to nonclinical factors such as area-level deprivation and racial disparities. By examining communitylevel factors such as area deprivation, this study engages both the medical and public health communities and places infant outcomes directly within the context of housing policy and lack of neighborhood investment. However, it is important that we articulate the connections between area deprivation and adverse outcomes for very preterm infants to even conceive …

Incidence And Risk Factors For Clinically Confirmed Secondary Bacterial Infections In Patients Hospitalized For Coronavirus Disease 2019 (Covid-19), Hiromichi S. Park, Caitlin M. Mccracken, Noah Lininger, Cara D. Varley, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Objective: The true incidence and risk factors for secondary bacterial infections in coronavirus disease 2019 (COVID-19) remains poorly understood. Knowledge of risk factors for secondary infections in hospitalized patients with COVID-19 is necessary to optimally guide selective use of empiric antimicrobial therapy. Design: Single-center retrospective cohort study of symptomatic inpatients admitted for COVID-19 from April 15, 2020, through June 30, 2021. Setting: Academic quaternary-care referral center in Portland, Oregon. Patients: The study included patients who were 18 years or older with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) PCR test up to 10 days prior to admission. Methods: …

The Experiences Of American Indian Participants And Site Coordinators In A Gestational Diabetes Risk Reduction Trial, Sarah Stotz, Kelly L. Gonzales, Kelly R. Moore, Heather Garrow, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Gestational diabetes mellitus is the most common complication of pregnancy and contributes to increased risk for type 2 diabetes in both the mother and offspring. We developed and evaluated a gestational diabetes risk reduction and preconception counseling program, Stopping GDM (SGDM), for American Indian females. The purpose of this study is to examine the experiences of American Indian mother-daughter dyad participants and the site coordinators who facilitated the SGDM randomized controlled trial to inform program revisions. We engaged mother-daughter dyads (n = 22 dyads) and site coordinators (n = 6) in focus group interviews. Four themes emerged: (1) …

Patients' Willingness To Accept Social Needs Navigation After In-Person Versus Remote Screening, Anna Louise Steeves-Reece, Melinda Marie Davis, Jean Hiebert Larson, Zoe Major-Mcdowall, Anne Elizabeth King, Christina Nicolaidis, Bruce Goldberg, Dawn Michele Richardson, Stephan Lindner

OHSU-PSU School of Public Health Faculty Publications and Presentations

Social needs screening and referral interventions are increasingly common in health care settings. Although remote screening offers a potentially more practical alternative to traditional in-person screening, there is concern that screening patients remotely could adversely affect patient engagement, including interest in accepting social needs navigation.

Building The Foundation For A Community Generated National Research Blueprint For Inherited Bleeding Disorders: Research Priorities In Health Services; Diversity, Equity, And Inclusion; And Implementation Science, Vanessa R. Byams, Judith Baker, Cindy Bailey, Alexis Dinno, Multiple Additonal Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: The National Hemophilia Foundation (NHF) conducted extensive all-stakeholder inherited bleeding disorder (BD) community consultations to inform a blueprint for future research. Sustaining and expanding the specialized and comprehensive Hemophilia Treatment Center care model, to better serve all people with inherited BDs (PWIBD), and increasing equitable access to optimal health emerged as top priorities. Research Design and Methods: NHF, with the American Thrombosis and Hemostasis Network (ATHN), convened multidisciplinary expert working groups (WG) to distill priority research initiatives from consultation findings. WG5 was charged with prioritizing health services research (HSR); diversity, equity, and inclusion (DEI); and implementation science (IS) research …

High Prep Uptake And Objective Longitudinal Adherence Among Hiv-Exposed Women With Personal Or Partner Plans For Pregnancy In Rural Uganda: A Cohort Study, Lynn T. Matthews, Esther Atukunda, Moran Owembabazi, Christina Psaros, David Bangsberg, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background

In Uganda, fertility rates and adult HIV prevalence are high, and many women conceive with partners living with HIV. Pre-exposure prophylaxis (PrEP) reduces HIV acquisition for women and, therefore, infants. We developed the Healthy Families-PrEP intervention to support PrEP use as part of HIV prevention during periconception and pregnancy periods. We conducted a longitudinal cohort study to evaluate oral PrEP use among women participating in the intervention.

Methods and findings

We enrolled HIV–negative women with plans for pregnancy with a partner living, or thought to be living, with HIV (2017 to 2020) to evaluate PrEP use among women participating …