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Articles 1 - 30 of 184
Full-Text Articles in Medicine and Health Sciences
Activity Of Prefrontal Cortex Subpopulations During Operant Alcohol Selfadministration, Grant Collins, H. Mejia Gomez, Faith Maxwell, Jessica M. Patel, Michael Salling
Activity Of Prefrontal Cortex Subpopulations During Operant Alcohol Selfadministration, Grant Collins, H. Mejia Gomez, Faith Maxwell, Jessica M. Patel, Michael Salling
Medical Student Research Poster Symposium
The National Institute of Alcohol Abuse and Alcoholism states, ‘according to the 2019 [National Survey on Drug Use and Health], 14.5 million (nearly 15 million) people ages 12 and older1 (5.3 percent of this age group2 ) had [alcohol use disorder (AUD)].’ The DSM-5 criteria for AUD includes compulsive drinking behavior.3 The prefrontal cortex (PFC) has roles in decisionmaking, response inhibition, and drug seeking and likely plays a role in compulsive alcohol drinking. However, the specific circuitry involved is unknown. There are two PFC circuits implicated in response inhibition or ‘stop’ behavior: PFC projections to the dorsomedial striatum (DMS) and …
Radiance1: Reducing Delays In Endometrial Cancer Care Symptoms Through Gynecologic Oncology Referral, Rebecca Maitski, Jessica Anderson, Hannah Sibley, Nicole Catalano, Kyla Maupin, Navya Nair, Tara Castellano, Andrew G. Chapple, Amelia Jernigan
Radiance1: Reducing Delays In Endometrial Cancer Care Symptoms Through Gynecologic Oncology Referral, Rebecca Maitski, Jessica Anderson, Hannah Sibley, Nicole Catalano, Kyla Maupin, Navya Nair, Tara Castellano, Andrew G. Chapple, Amelia Jernigan
Medical Student Research Poster Symposium
Objective: In this cohort of women seeking care at a university practice in the Gulf South, we aimed to identify specific delays from patient experience of abnormal uterine bleeding (AUB) to referral to gynecologic oncology (GON) with a diagnosis of endometrial cancer (EC). Methods: A multicenter, IRB-approved retrospective chart review was performed. Women diagnosed with Stage I-IV endometrial cancer from 2013 to 2022 were included. Demographic, pathologic and treatment data were collected. Symptom duration and key appointment, procedure, or result dates were recorded. Time frames between key events were calculated. Timed events were censored if there was insufficient data to …
Does Vehicle Intrusion Alone Still Predict Injury: A Retrospective Analysis Of Mechanism As Trauma Activation Criteria, Harrison Travis, Sarah Muramoto, Alison Smith, John Hunt, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, Alan Marr
Does Vehicle Intrusion Alone Still Predict Injury: A Retrospective Analysis Of Mechanism As Trauma Activation Criteria, Harrison Travis, Sarah Muramoto, Alison Smith, John Hunt, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, Alan Marr
Medical Student Research Poster Symposium
Background: Current Centers for Disease Control (CDC) Guidelines for ‘Field Triage of Injured’ recommend patients involved in automobile collisions with greater than 12 inches of intrusion on the driver side or 18 inches on the passenger compartment should meet criteria for trauma activations. However, previous studies suggest that mechanism-of-injury (MOI) criteria only is a moderate predictor for patients who require trauma center resources given the introduction of “crumple zones” to cars. Crumple zones have been incorporated into modern vehicle design as a safety feature. The objective of this study was to determine if vehicle intrusion alone as MOI criteria necessitates …
Predictors Of Equitable Receipt Of Next Generation Sequencing In Endometrial Cancerpatients Receiving Cancer Care In The Deep South, Amber R. Bardarson, Madison A. Keller, Afryea L. Dunbar, Yaseen Khan, Amelia M. Jernigan, Navya Nair, Andrew Chapple, Tara Castellano
Predictors Of Equitable Receipt Of Next Generation Sequencing In Endometrial Cancerpatients Receiving Cancer Care In The Deep South, Amber R. Bardarson, Madison A. Keller, Afryea L. Dunbar, Yaseen Khan, Amelia M. Jernigan, Navya Nair, Andrew Chapple, Tara Castellano
Medical Student Research Poster Symposium
Socioeconomic status remains a predictor of endometrial cancer prognosis and is correlated with advanced disease in patients. Next Generation Sequencing (NGS) provides the ability to prescribe targeted cancer therapies and increases patient survival. Race, ethnicity, and insurance status impact the use of NGS analysis, though the degree of impact remains unclear. An IRB-Approved retrospective research study was performed using data collected of gynecologic cancer patients in a southern healthcare system through use of the electronic medical record (EMR). Baseline clinicopathologic and demographic factors were collected for all endometrial cancer patients. These factors were then tested for significant association on whether …
Removal Of Permanent Ivc Filter, Sarah Aleman, Hector Ferral
Removal Of Permanent Ivc Filter, Sarah Aleman, Hector Ferral
Medical Student Research Poster Symposium
A 53-year-old woman with history of Crohn’s disease was referred to interventional radiology for inferior vena cava (IVC) filter removal with the diagnosis of a fractured IVC filter. At the time of evaluation, in early 2022, the patient reported back pain. No imaging was available when the patient was first seen. The IVC filter was originally placed in 2011. The indication for filter placement was the presence of deep vein thrombosis (DVT) shortly after small bowel resection. At the time, anticoagulation was contraindicated. Upon spectral CT imaging, several legs of the IVC filter were found to be protruding outside the …
Prolonged Administration Of Kappa Opioid Agonist Difelikefalin Retains Its Efficacyon The Diuretic Response, Ashlyn Y. Anderson, Luke E. Beckendorf, Daniel R. Kapusta
Prolonged Administration Of Kappa Opioid Agonist Difelikefalin Retains Its Efficacyon The Diuretic Response, Ashlyn Y. Anderson, Luke E. Beckendorf, Daniel R. Kapusta
Medical Student Research Poster Symposium
RATIONALE: Disease states exhibiting high amounts of edema, including congestive heart failure, hepatic cirrhosis, and hypertension, are often treated with a combination of diuretics to reduce water retention in the body. Patients treated with the loop diuretic furosemide face an increased risk for developing adverse conditions, such as hyponatremia and hypokalemia and with time loss of diuretic efficacy (diuretic resistance). In contrast, the kappa opioid agonist difelikefalin produces a sodium sparing diuresis by inhibiting hypothalamic neurons responsible for the secretion/release of antidiuretic hormone (ADH) located in the paraventricular nucleus (PVN). Consequently, inhibition of ADH release increases urine output by increasing …
Radiance2: Reducing Delays In Endometrial Cancer Care Gynecologic Oncology Care, Jessica Anderson, Kyla Maupin, Hannah Sibley, Nicole Catalano, Rebecca Maitski, Navya Nair, Tara Castellano, Andrew Chapple, Amelia Jernigan
Radiance2: Reducing Delays In Endometrial Cancer Care Gynecologic Oncology Care, Jessica Anderson, Kyla Maupin, Hannah Sibley, Nicole Catalano, Rebecca Maitski, Navya Nair, Tara Castellano, Andrew Chapple, Amelia Jernigan
Medical Student Research Poster Symposium
We aimed to identify actionable delays in care that for women with endometrial cancer (EC) from the time of gynecologic oncology (GON) referral through adjuvant therapy. A multicenter, IRB-approved retrospective chart review was performed. Women diagnosed with Stage I-IV endometrial cancer from 2013 to 2022 were included. Demographic, pathologic, treatment, and survival data were collected. Time frames between key events were calculated. Timed events were censored if there was insufficient data to make a calculation. Categorical covariates were summarized with counts and percentages; continuous variables were summarized via means and standard deviations. Categorical covariates were compared across groups using a …
Retinal Degeneration In Mice Devoid Of Membrane-Type Frizzled-Related Proteinor Adiponectin Receptor 1 Results In Selective Fatty Acid Synthesis Impairments, Alise J. Aucoin, Marie-Audrey Kautzmann Guerin, William Gordon, Eric Prestenburg, Jeff Ji, Rasangi Perera, Nicolas Bazan
Retinal Degeneration In Mice Devoid Of Membrane-Type Frizzled-Related Proteinor Adiponectin Receptor 1 Results In Selective Fatty Acid Synthesis Impairments, Alise J. Aucoin, Marie-Audrey Kautzmann Guerin, William Gordon, Eric Prestenburg, Jeff Ji, Rasangi Perera, Nicolas Bazan
Medical Student Research Poster Symposium
Abnormal lipid metabolism is the derivation of multiple retinal degenerative and blinding diseases. The membrane-type frizzled-related protein (MFRP), and adiponectin receptor 1 (AdipoR1) were shown to be vital to the maintenance of a healthy retinal lipidome. The two mice models of retinal degenerations Mfrprd6 and Adipor1 -/- resulted in a reduction of phospholipids containing docosahexaenoic acid (DHA; 22:6) and very long-chain polyunsaturated fatty acids (VLC-PUFAs). In a pathway involving the ω-3 fatty acids eicosapentaenoic acid (EPA; 20:5) and docosahexaenoic acid (DHA; 22:6), the fatty acid elongase-4 (ELOVL4) elongates the fatty acid 28:6 into VLC-PUFAs, which are precursors to potent neuroprotective …
Evaluation Of Medial Branch Blocks For Lumbar Facet Joint Radiofrequency Ablation: What Is The Role Of The Second Diagnostic Block?, Alexandra Bartholomew, Noah Hoffman, David Provenzano, Todd Sitzman
Evaluation Of Medial Branch Blocks For Lumbar Facet Joint Radiofrequency Ablation: What Is The Role Of The Second Diagnostic Block?, Alexandra Bartholomew, Noah Hoffman, David Provenzano, Todd Sitzman
Medical Student Research Poster Symposium
Lumbar medial branch (LMB) radiofrequency ablation (RFA) is a commonly performed procedure to treat facet joint-mediated pain. One of the challenges associated with LMB RFA is appropriately selecting patients for the procedure. Currently, patient history, physical examination, and diagnostic studies inadequately select patients for RFA. Therefore, diagnostic local anesthetic blocks are often recommended, yet the type and number of blocks needed to appropriately select patients for LMB RFA are debated. Success rates have been shown to be higher when dual blocks are employed; however, there are additional costs, humanistic factors, and risks of excluding individuals that may benefit from RFA. …
The Effects Of Alcohol Consumption On Metabolic Factors In The Alive-Ex Study Participants, Meva Beganovic, Stefany D. Primeaux
The Effects Of Alcohol Consumption On Metabolic Factors In The Alive-Ex Study Participants, Meva Beganovic, Stefany D. Primeaux
Medical Student Research Poster Symposium
Alcohol consumption among people living with HIV (PLWH) is common and increases the risk for metabolic disorders such as insulin resistance and diabetes. Adiponectin is an adipokine, produced in adipocytes, that protects against insulin resistance by increasing insulin sensitivity and thus may play a preventative role against the development of metabolic disease. Previous studies have demonstrated an inconsistency regarding the impact of alcohol consumption on adiponectin levels. In a cross-sectional analysis of participants enrolled in the ALIVE-Ex Study, we did not find a significant relationship between at-risk alcohol use, as measured by Alcohol Use Disorders Identification Test (AUDIT) score, in …
Multi-Dermatomal Herpes Zoster Infection As The Presenting Symptom Of Underlyingductal Carcinoma, Kaylin Beiter, Carrie Pham, Vince Cataldo, Jessica Lacombe
Multi-Dermatomal Herpes Zoster Infection As The Presenting Symptom Of Underlyingductal Carcinoma, Kaylin Beiter, Carrie Pham, Vince Cataldo, Jessica Lacombe
Medical Student Research Poster Symposium
Herpes zoster infection has been associated with a significantly increased risk of future all-cause cancer incidence. In addition, zoster infections, when involving the breast, may mimic breast malignancy, and this similar phenotype may present a diagnostic challenge for clinicians. Few cases of concurrent infection and any malignancy have been reported. We present the case of a herpes zoster infection that was associated with concurrent breast malignancy. A 62-year-old woman with a history of coronary artery disease, hypertension, and reduced ejection heart failure presented to the emergency department for a four-week history of rash of her left upper back and breast. …
Chronic High Salt Diets Contribute To Neurogenic Hypertension By Increasing B1r Expressionand B1r-Mediated Ace2 Internalization And Degradation, Jagnoor Benipal, Navya Lakkapa, Anna Nuzzo, Mona Elgazzaz, Eric Lazartigues
Chronic High Salt Diets Contribute To Neurogenic Hypertension By Increasing B1r Expressionand B1r-Mediated Ace2 Internalization And Degradation, Jagnoor Benipal, Navya Lakkapa, Anna Nuzzo, Mona Elgazzaz, Eric Lazartigues
Medical Student Research Poster Symposium
The Centers for Disease Control and Prevention estimates that hypertension affects nearly 50% of Americans1 . Previous studies have shown that chronically elevated dietary salt intake contributes to developing neurogenic hypertension2 . Additionally, increased expression of the bradykinin B1 receptor (B1R) in neurons in the hypothalamic paraventricular nucleus (PVN) is seen in neurogenic hypertension which leads to neuroinflammation and oxidative stress3 . Angiotensin-converting enzyme 2 (ACE2) is a key enzyme in the renin-angiotensin system (RAS) pathway that mitigates the vasoconstrictive effects of Angiotensin (Ang) II by cleaving it to Ang-(1-7)4 . We previously observed that the binding of Ang-II to …
Radiance1: Reducing Delays In Endometrial Cancer Care Symptomsthrough Gynecologic Oncology Referral, Nicole Catalano, Jessica Anderson, Kyla Maupin, Hannah Sibley, Rebecca Maitski, Navaya Nair, Tara Castellano, Andrew Chapple, Amelia Jernigan
Radiance1: Reducing Delays In Endometrial Cancer Care Symptomsthrough Gynecologic Oncology Referral, Nicole Catalano, Jessica Anderson, Kyla Maupin, Hannah Sibley, Rebecca Maitski, Navaya Nair, Tara Castellano, Andrew Chapple, Amelia Jernigan
Medical Student Research Poster Symposium
Objective: In this cohort of women seeking care at a university practice in the Gulf South, we aimed to identify specific delays from patient experience of abnormal uterine bleeding (AUB) to referral to gynecologic oncology (GON) with a diagnosis of endometrial cancer (EC). Methods: A multicenter, IRB-approved retrospective chart review was performed. Women diagnosed with Stage I-IV endometrial cancer from 2013 to 2022 were included. Demographic, pathologic and treatment data were collected. Symptom duration and key appointment, procedure, or result dates were recorded. Time frames between key events were calculated. Timed events were censored if there was insufficient data to …
Nk Cells In Uterine Cancers, Schumann Chang, Vijay Kumar, Caitlin Bauer, John Stewart
Nk Cells In Uterine Cancers, Schumann Chang, Vijay Kumar, Caitlin Bauer, John Stewart
Medical Student Research Poster Symposium
Uterine cancer, which includes endometrial cancer (EC) and cervical cancer (CC), is one of the most prevalent gynecologic malignancies amongst women. It is the fourth most common cancer for women in the United States, with more than 90% of uterine cancers occurring in the endometrium. The uterus is a mucosal immune organ that supports embryonic and fetal development. However, its immune microenvironment is continuously altered depending on female sex hormones status, which varies with menstrual cycle and pregnancy. While pregnancy is considered a controlled stage of inflammation, this is not the case in carcinogenesis. This review paper focuses on NK …
In-Depth Analysis Of Next-Generation Sequencing (Ngs) And Bioinformatics Results In Pediatric Adgrv1 Compound Heterozygotes, Sloane Clay, Adele Evans, Chindo Hicks, David Otohinoyi
In-Depth Analysis Of Next-Generation Sequencing (Ngs) And Bioinformatics Results In Pediatric Adgrv1 Compound Heterozygotes, Sloane Clay, Adele Evans, Chindo Hicks, David Otohinoyi
Medical Student Research Poster Symposium
Genetic diagnosis of sensorineural hearing loss (SNHL) using NGS proves challenging when encountering multigenic, multiallelic variants of uncertain significance (VUS). These VUS make it difficult to provide anticipatory guidance regarding progressive disorders such as Type II Usher syndrome (SNHL at birth and retinitis pigmentosa in the second decade of life). With genetic testing companies are identifying, reporting, and reclassifying VUS at a rapid pace; there is a need for in depth-analysis and interpretation. For example, VUS in ADGRV1, a gene implicated in Type II Usher Syndrome, may be inherited in a compound heterozygous manner and misinterpreted as benign, when in …
An Algorithm To Prevent Missed Bowel Injuries In Blunt And Penetrating Abdominal Trauma Patients, Ashley Clement, Logan Gold, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, John Hunt, Alan Marr, Monique St. Romain, Alison Smith
An Algorithm To Prevent Missed Bowel Injuries In Blunt And Penetrating Abdominal Trauma Patients, Ashley Clement, Logan Gold, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, John Hunt, Alan Marr, Monique St. Romain, Alison Smith
Medical Student Research Poster Symposium
Background: Bowel injuries from trauma require immediate recognition and operative intervention. Missed bowel result in significant morbidity and mortality such as infection, enterocutaneous fistulas, additional surgeries, prolonged hospitalization, and mortality. Clinical and diagnostic expertise are limited as significant blunt bowel and/or mesenteric injuries can be evasive to detect with current imaging modalities, and physical exam findings can be unreliable. Current guidelines for the management of patients with a possible bowel injury do not offer clear direction. Objective: The objective of this study was to develop decision-making algorithms to identify patients at high risk for missed bowel injuries. Methods: A retrospective …
The Fecal Position: Tracking Progressive Dna Repeat Expansion Via Stool Dna Extraction, Margaret Conrad, Hayley Ulloa, Ed Grabczyk
The Fecal Position: Tracking Progressive Dna Repeat Expansion Via Stool Dna Extraction, Margaret Conrad, Hayley Ulloa, Ed Grabczyk
Medical Student Research Poster Symposium
Friedreich Ataxia is a progressive DNA repeat expansion disease. Examining DNA repeat expansion in mouse models require sacrificing the mouse and taking samples of organs. The obvious non-lethal targets, such as ears, tails, and blood do not have levels of repeat expansion comparable to internal organs. However, recent publications suggest that stool may be a suitable non-lethal candidate for tracking repeat expansion over time. Stool DNA may allow researchers to monitor the effect of interventions aimed at slowing DNA repeat expansion over time without harming the mouse. A commercial kit was first used to extract DNA from feces without success. …
Neurosyphilis, Lymphogranuloma Venereum, And N. Gonorrhea Reveal Importance Of Appropriate Sti Testing And Follow-Up, Sarah Corley, Caila Knighton, Hope Oddo Moise
Neurosyphilis, Lymphogranuloma Venereum, And N. Gonorrhea Reveal Importance Of Appropriate Sti Testing And Follow-Up, Sarah Corley, Caila Knighton, Hope Oddo Moise
Medical Student Research Poster Symposium
A 38-year-old male presented to the emergency department with complaints of a painful penile ulcer for four weeks. Six months prior to presentation, the patient was diagnosed with secondary syphilis and clinically treated with Bicillin; however, RPR titers posttreatment were not ordered, as is standard of care. One week before presentation, the patient visited his primary care physician and had a urine PCR screening for sexually transmitted infection, which provided the diagnosis of Chlamydia. This infection was treated with azithromycin. Following no improvement from treatment, the patient presented to the ED with the complaint of painful penile lesion x days, …
Barriers That Contribute To Disparities Seen In The Prenatal Diagnosis Of Congenital Heart Disease In Patients With Government-Funded Health Insurance, Olivia Crapanzano, Lauren Haddad, Kathleen Crapanzano
Barriers That Contribute To Disparities Seen In The Prenatal Diagnosis Of Congenital Heart Disease In Patients With Government-Funded Health Insurance, Olivia Crapanzano, Lauren Haddad, Kathleen Crapanzano
Medical Student Research Poster Symposium
BACKGROUND: Multiple national studies have established an inverse relationship between surgical center volume and surgical outcomes in pediatric cardiac surgery. The aim of the initial study was to determine whether surgical outcomes for a private, outpatient pediatric cardiology practice that was not associated with a surgical center, differed based on the surgical center volume to which the patient was referred. While we did not find significant differences in clinical outcomes related to surgical center volume, race or insurance status during the initial study, important disparities to care were identified. Children with private insurance were more likely to be diagnosed prenatally …
Genitourinary And Sexual Health Care For Women With Cancer: Overlooked Quality Of Life Indicators, Hannah C. Dellacroce, Nancy L. Ren, Andrew G. Chapple, Sydni Barras, Shawna Morron, Tara Castellano, Navya Nair, Amelia Jernigan
Genitourinary And Sexual Health Care For Women With Cancer: Overlooked Quality Of Life Indicators, Hannah C. Dellacroce, Nancy L. Ren, Andrew G. Chapple, Sydni Barras, Shawna Morron, Tara Castellano, Navya Nair, Amelia Jernigan
Medical Student Research Poster Symposium
BACKGROUND: Genitourinary health and sexual well-being are critical aspects of quality of life and overall health, especially for patients with malignancy who face the negative physical and emotional consequences of cancer and cancer treatment. However, evidence suggests that physicians rarely address these concerns in clinical practice. As cancer survivorship continues to improve with advancements in detection and treatment, the need for supportive gynecologic and sexual health care for women with cancer is greater than ever. The purpose of this study was to characterize the prevalence of oncologist-reported counseling for genitourinary syndromes (GUS) or sexual health concerns (SHC) in women with …
Diversifying Clinical Trials: Does Presentation At Gynecologic Oncology Tumor Board Increase Equitable Access To Clinical Trials For Black And Latinx Patients?, Afryea L. Dunbar, Fraya G. King, Madison A. Keller, Yaseen Khan, Amber R. Bardarson, Amelia Jernigan, Andrew G. Chapple, Tara Castellano, Navya Nair
Diversifying Clinical Trials: Does Presentation At Gynecologic Oncology Tumor Board Increase Equitable Access To Clinical Trials For Black And Latinx Patients?, Afryea L. Dunbar, Fraya G. King, Madison A. Keller, Yaseen Khan, Amber R. Bardarson, Amelia Jernigan, Andrew G. Chapple, Tara Castellano, Navya Nair
Medical Student Research Poster Symposium
Background: Tumor boards are multidisciplinary cancer conferences held to review all the clinical data, evidence-based guidelines, latest literature, and available clinical trials for each cancer case that is discussed. Objectives: This study aims to determine whether presentation at gynecologic oncology tumor board (GO TB) increases clinical trial enrollment of black and latinX cancer patients. Methods: A retrospective chart review of all cases presented at multidisciplinary GO TB from Jan 2019 – Jun 2022 were analyzed. For each case, demographic and cancer-specific variables as well as tumor board discussions regarding clinical trials were collected. Continuous covariates were summarized within groups by …
Multianalyte Association Between Intestinal Alkaline Phosphatase And Pediatric Inflammatory Bowel Disease, Rebekah Fayard, Rebecca Buckley, Micquel Downs, Eileen Lugo-Perez, Anne Tufton, Colleen Leblanc, Dedrick Moulton, Sunyoung Kim
Multianalyte Association Between Intestinal Alkaline Phosphatase And Pediatric Inflammatory Bowel Disease, Rebekah Fayard, Rebecca Buckley, Micquel Downs, Eileen Lugo-Perez, Anne Tufton, Colleen Leblanc, Dedrick Moulton, Sunyoung Kim
Medical Student Research Poster Symposium
Inflammatory bowel disease (IBD) is a generalized inflammatory gastrointestinal (GI) disease that includes Ulcerative Colitis (UC) and Crohn’s disease (CD). Consideration of diagnostic choices outside of endoscopy are urgent, and especially so for the pediatric population. A growing number of diagnosed IBD cases with rates up to 25% of all IBD occurrences are pediatric cases. Current available fecal markers have yet to satisfy desired characteristics. For example, thus far, they can achieve moderate specificity but low sensitivity, but they cannot reliably stratify patients into a quiescent, mild, moderately active, or severe disease states. Intestinal alkaline phosphatase (iAP), an enzyme shed …
Local Control Of Pyoderma Gangrenosum, Cameron J. Fontenot, Mark A. Maier, Nicholas Taylor, Alison A. Smith, Frank Lau
Local Control Of Pyoderma Gangrenosum, Cameron J. Fontenot, Mark A. Maier, Nicholas Taylor, Alison A. Smith, Frank Lau
Medical Student Research Poster Symposium
Background: Pyoderma gangrenosum (PG) is a rare, non-infectious neutrophilic dermatosis that presents as painful, ulcerative, non-healing wounds. Pathergy, defined as hyperreactivity of the skin following minor trauma, is one of the hallmarks of PG. Currently, there is no consensus involving the diagnosis, treatment, and management of PG. A recent case report demonstrated that the use of a dehydrated human amnion/chorion membrane (dHACM) following surgical debridement in a single patient promoted wound healing. However, the physiologic mechanism underlying the effects of PG wound treatment with dHACM remains unknown. Objective: The objective of this study is to characterize and compare PG wounds …
Describing The Prevalence And Unique Demographic And Clinicopathologic Features Of Hpv-Negative Cervical Cancer, Caitlyn C. Gallaspy, Joshua R. Ricks, Navya Nair, Tara Castellano, Andrew G. Chapple, Amelia M. Jernigan
Describing The Prevalence And Unique Demographic And Clinicopathologic Features Of Hpv-Negative Cervical Cancer, Caitlyn C. Gallaspy, Joshua R. Ricks, Navya Nair, Tara Castellano, Andrew G. Chapple, Amelia M. Jernigan
Medical Student Research Poster Symposium
HPV-negative cervical cancer (HPV-CC) has been described to represent 10% of cervical cancer cases and to be associated with more advanced presentation and attenuated survival outcomes. The objective of this study was to describe the prevalence of HPV-CC in our region and to compare demographics and clinicopathologic features of HPV-CC to HPV-positive cervical cancer (HPV+CC). A retrospective chart review of patients diagnosed with cervical cancer at a safety-net hospital between January 1, 2015 and December 31, 2020 was conducted. HPV status was determined by HPV testing within 6 months of histologic diagnosis. HPV-CC was defined as a negative HPV test …
Medical Therapy And Sinus Surgery For The Treatment Of Chronic Rhinosinusitis: Indications For Louisiana Medicaid, Hayden J. Guidry, Sanket Dhruva, Rita Redberg
Medical Therapy And Sinus Surgery For The Treatment Of Chronic Rhinosinusitis: Indications For Louisiana Medicaid, Hayden J. Guidry, Sanket Dhruva, Rita Redberg
Medical Student Research Poster Symposium
Background: Chronic rhinosinusitis (CRS) is common and incurs a significant human and economic cost. CRS is defined as symptomatic inflammation of the paranasal sinuses and nasal cavities lasting longer than 12 weeks. Treatments include medical therapy such as saline irrigation, nasal corticosteroids, oral antibiotics, biologics, and other agents as well as procedures such as balloon ostial dilation and functional endoscopic sinus surgery (FESS). In an analysis of Louisiana Medicaid’s expenditures for calendar year 2019, there were 1,102 distinct recipients of sinus surgery (either balloon ostial dilation or FESS) for a total of $2,382,366 in professional services expenditures. Objective: This study …
Estrogen, Obesity, And Anticoagulant Protein S Contribute To Thrombosis In Mice, Alaina Guilbeau, Manoj Kumar, Laurent Mosnier, Rinku Majumder
Estrogen, Obesity, And Anticoagulant Protein S Contribute To Thrombosis In Mice, Alaina Guilbeau, Manoj Kumar, Laurent Mosnier, Rinku Majumder
Medical Student Research Poster Symposium
Protein S (PS) is an anticoagulant molecule present in humans and mice. Protein S binds and inhibits coagulation Factor IXa to control thrombin generation1 . Protein S is imperative for normal hemostasis and the prevention of life-threatening thrombotic events, as demonstrated by numerous studies of patients with PS deficiency2,3,4. Pregnant women5 and women who use estrogen-containing birth control pills 6 have lower levels of PS. Thus, it is postulated that estrogen downregulates PS expression in human. Because estrogen is synthesized by aromatase, which is highly expressed in adipose tissue7 , we expected that PS will be downregulated in obese mice …
A Case Of Cryptococcal Meningoencephalitis In An Immunocompetent Patient With Chiari I Malformation, Shreya Gunda, Victoria Silver, Kimiknu Mentore, Lauren Nunez
A Case Of Cryptococcal Meningoencephalitis In An Immunocompetent Patient With Chiari I Malformation, Shreya Gunda, Victoria Silver, Kimiknu Mentore, Lauren Nunez
Medical Student Research Poster Symposium
Over 90% of cases of cryptococcal meningoencephalitis present in immunocompromised patients, with the majority of those being in patients with AIDS. However, this infection can also occur in other immunocompromised states, such as steroid use, malignancy, rheumatologic diseases, and use of immunosuppressive medications. Delay in diagnosis can often lead to rapid neurological deterioration and mortality. We present a case of a young, otherwise immunocompetent patient, with history of Chiari I malformation and recent COVID-19 infection, found to have cryptococcal meningitis. The patient presented with syncope following two weeks of headaches, generalized body aches and weakness after COVID-19 diagnosis, and was …
Manual Vacuum Aspiration: Familiarity And Comfort Among Obgyn Physicians At Louisiana State University, Alexis Hernandez, Stacey Scheib
Manual Vacuum Aspiration: Familiarity And Comfort Among Obgyn Physicians At Louisiana State University, Alexis Hernandez, Stacey Scheib
Medical Student Research Poster Symposium
Background: Manual vacuum aspiration (MVA) uses a hand-held aspirator to generate a vacuum to aspirate uterine contents for management of early pregnancy loss or elective abortion prior to 12 weeks gestation. According to the American College of Obstetricians and Gynecologists, MVA is a safe, costsaving procedure that promotes patient comfort, convenience, and privacy. Despite the advantages of this procedure, it is often overlooked in favor of electric suction or dilation and curettage, more extensive procedures that are associated with increased cost and post-procedural pain and bleeding. The goal of this study is to assess the attitudes, familiarity, and comfort towards …
Prospective Observational Registry Study Of Myriad™ Matrix And Myriad™ Morcells In Soft Tissue Reconstruction, Tyler Hernandez, Cameron Fontenot, Cayley Leblanc, Paige Deville, Frank Lau, Alison Smith
Prospective Observational Registry Study Of Myriad™ Matrix And Myriad™ Morcells In Soft Tissue Reconstruction, Tyler Hernandez, Cameron Fontenot, Cayley Leblanc, Paige Deville, Frank Lau, Alison Smith
Medical Student Research Poster Symposium
Soft tissue reconstruction is a procedure that is fundamental to the practice of surgery. Due to the paramount importance of soft tissue repair, the need to improve this procedure through the use of modernized technologies is ever-present. Myriad Matrix is an intact extracellular matrix (ECM) that is available in a 3-layer or a 5-layer configuration. It is derived from ovine (sheep) forestomach tissue and retains the innate biological structure of the native ECM-associated macromolecules, including elastin, fibronectin, glycosaminoglycans, and laminin. When rehydrated with wound exudate or sterile saline, Myriad Matrix transforms into a malleable and compliant sheet that naturally incorporates …
Ophthalmology Consult Order: “Rule Out Open Globe Injury, Ellen Ingram, Matthew Williams, Kevin Kirchner
Ophthalmology Consult Order: “Rule Out Open Globe Injury, Ellen Ingram, Matthew Williams, Kevin Kirchner
Medical Student Research Poster Symposium
Out of traumatic eye injuries, open globe injuries are associated with the highest patient morbidity. Computed tomography (CT) imaging of the orbits is routinely used by the emergency department physician during workup of traumatic eye injuries. Positive CT findings reliably indicate penetration of the globe with a specificity up to 98% [1]. However, studies have consistently shown that CT imaging fails to diagnose approximately 30% of open globe injuries [1,2]. Therefore, a negative CT scan does not definitively rule out an open globe. There are no defined exam parameters that have been established as reliable indicators for open globe injuries …