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Nk Cells In Uterine Cancers, Schumann Chang, Vijay Kumar, Caitlin Bauer, John Stewart Oct 2022

Nk Cells In Uterine Cancers, Schumann Chang, Vijay Kumar, Caitlin Bauer, John Stewart

Medical Student Research Poster Symposium

Uterine cancer, which includes endometrial cancer (EC) and cervical cancer (CC), is one of the most prevalent gynecologic malignancies amongst women. It is the fourth most common cancer for women in the United States, with more than 90% of uterine cancers occurring in the endometrium. The uterus is a mucosal immune organ that supports embryonic and fetal development. However, its immune microenvironment is continuously altered depending on female sex hormones status, which varies with menstrual cycle and pregnancy. While pregnancy is considered a controlled stage of inflammation, this is not the case in carcinogenesis. This review paper focuses on NK …


An Algorithm To Prevent Missed Bowel Injuries In Blunt And Penetrating Abdominal Trauma Patients, Ashley Clement, Logan Gold, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, John Hunt, Alan Marr, Monique St. Romain, Alison Smith Oct 2022

An Algorithm To Prevent Missed Bowel Injuries In Blunt And Penetrating Abdominal Trauma Patients, Ashley Clement, Logan Gold, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, John Hunt, Alan Marr, Monique St. Romain, Alison Smith

Medical Student Research Poster Symposium

Background: Bowel injuries from trauma require immediate recognition and operative intervention. Missed bowel result in significant morbidity and mortality such as infection, enterocutaneous fistulas, additional surgeries, prolonged hospitalization, and mortality. Clinical and diagnostic expertise are limited as significant blunt bowel and/or mesenteric injuries can be evasive to detect with current imaging modalities, and physical exam findings can be unreliable. Current guidelines for the management of patients with a possible bowel injury do not offer clear direction. Objective: The objective of this study was to develop decision-making algorithms to identify patients at high risk for missed bowel injuries. Methods: A retrospective …


The Fecal Position: Tracking Progressive Dna Repeat Expansion Via Stool Dna Extraction, Margaret Conrad, Hayley Ulloa, Ed Grabczyk Oct 2022

The Fecal Position: Tracking Progressive Dna Repeat Expansion Via Stool Dna Extraction, Margaret Conrad, Hayley Ulloa, Ed Grabczyk

Medical Student Research Poster Symposium

Friedreich Ataxia is a progressive DNA repeat expansion disease. Examining DNA repeat expansion in mouse models require sacrificing the mouse and taking samples of organs. The obvious non-lethal targets, such as ears, tails, and blood do not have levels of repeat expansion comparable to internal organs. However, recent publications suggest that stool may be a suitable non-lethal candidate for tracking repeat expansion over time. Stool DNA may allow researchers to monitor the effect of interventions aimed at slowing DNA repeat expansion over time without harming the mouse. A commercial kit was first used to extract DNA from feces without success. …


Neurosyphilis, Lymphogranuloma Venereum, And N. Gonorrhea Reveal Importance Of Appropriate Sti Testing And Follow-Up, Sarah Corley, Caila Knighton, Hope Oddo Moise Oct 2022

Neurosyphilis, Lymphogranuloma Venereum, And N. Gonorrhea Reveal Importance Of Appropriate Sti Testing And Follow-Up, Sarah Corley, Caila Knighton, Hope Oddo Moise

Medical Student Research Poster Symposium

A 38-year-old male presented to the emergency department with complaints of a painful penile ulcer for four weeks. Six months prior to presentation, the patient was diagnosed with secondary syphilis and clinically treated with Bicillin; however, RPR titers posttreatment were not ordered, as is standard of care. One week before presentation, the patient visited his primary care physician and had a urine PCR screening for sexually transmitted infection, which provided the diagnosis of Chlamydia. This infection was treated with azithromycin. Following no improvement from treatment, the patient presented to the ED with the complaint of painful penile lesion x days, …


Barriers That Contribute To Disparities Seen In The Prenatal Diagnosis Of Congenital Heart Disease In Patients With Government-Funded Health Insurance, Olivia Crapanzano, Lauren Haddad, Kathleen Crapanzano Oct 2022

Barriers That Contribute To Disparities Seen In The Prenatal Diagnosis Of Congenital Heart Disease In Patients With Government-Funded Health Insurance, Olivia Crapanzano, Lauren Haddad, Kathleen Crapanzano

Medical Student Research Poster Symposium

BACKGROUND: Multiple national studies have established an inverse relationship between surgical center volume and surgical outcomes in pediatric cardiac surgery. The aim of the initial study was to determine whether surgical outcomes for a private, outpatient pediatric cardiology practice that was not associated with a surgical center, differed based on the surgical center volume to which the patient was referred. While we did not find significant differences in clinical outcomes related to surgical center volume, race or insurance status during the initial study, important disparities to care were identified. Children with private insurance were more likely to be diagnosed prenatally …


Genitourinary And Sexual Health Care For Women With Cancer: Overlooked Quality Of Life Indicators, Hannah C. Dellacroce, Nancy L. Ren, Andrew G. Chapple, Sydni Barras, Shawna Morron, Tara Castellano, Navya Nair, Amelia Jernigan Oct 2022

Genitourinary And Sexual Health Care For Women With Cancer: Overlooked Quality Of Life Indicators, Hannah C. Dellacroce, Nancy L. Ren, Andrew G. Chapple, Sydni Barras, Shawna Morron, Tara Castellano, Navya Nair, Amelia Jernigan

Medical Student Research Poster Symposium

BACKGROUND: Genitourinary health and sexual well-being are critical aspects of quality of life and overall health, especially for patients with malignancy who face the negative physical and emotional consequences of cancer and cancer treatment. However, evidence suggests that physicians rarely address these concerns in clinical practice. As cancer survivorship continues to improve with advancements in detection and treatment, the need for supportive gynecologic and sexual health care for women with cancer is greater than ever. The purpose of this study was to characterize the prevalence of oncologist-reported counseling for genitourinary syndromes (GUS) or sexual health concerns (SHC) in women with …


Describing The Prevalence And Unique Demographic And Clinicopathologic Features Of Hpv-Negative Cervical Cancer, Caitlyn C. Gallaspy, Joshua R. Ricks, Navya Nair, Tara Castellano, Andrew G. Chapple, Amelia M. Jernigan Oct 2022

Describing The Prevalence And Unique Demographic And Clinicopathologic Features Of Hpv-Negative Cervical Cancer, Caitlyn C. Gallaspy, Joshua R. Ricks, Navya Nair, Tara Castellano, Andrew G. Chapple, Amelia M. Jernigan

Medical Student Research Poster Symposium

HPV-negative cervical cancer (HPV-CC) has been described to represent 10% of cervical cancer cases and to be associated with more advanced presentation and attenuated survival outcomes. The objective of this study was to describe the prevalence of HPV-CC in our region and to compare demographics and clinicopathologic features of HPV-CC to HPV-positive cervical cancer (HPV+CC). A retrospective chart review of patients diagnosed with cervical cancer at a safety-net hospital between January 1, 2015 and December 31, 2020 was conducted. HPV status was determined by HPV testing within 6 months of histologic diagnosis. HPV-CC was defined as a negative HPV test …


Medical Therapy And Sinus Surgery For The Treatment Of Chronic Rhinosinusitis: Indications For Louisiana Medicaid, Hayden J. Guidry, Sanket Dhruva, Rita Redberg Oct 2022

Medical Therapy And Sinus Surgery For The Treatment Of Chronic Rhinosinusitis: Indications For Louisiana Medicaid, Hayden J. Guidry, Sanket Dhruva, Rita Redberg

Medical Student Research Poster Symposium

Background: Chronic rhinosinusitis (CRS) is common and incurs a significant human and economic cost. CRS is defined as symptomatic inflammation of the paranasal sinuses and nasal cavities lasting longer than 12 weeks. Treatments include medical therapy such as saline irrigation, nasal corticosteroids, oral antibiotics, biologics, and other agents as well as procedures such as balloon ostial dilation and functional endoscopic sinus surgery (FESS). In an analysis of Louisiana Medicaid’s expenditures for calendar year 2019, there were 1,102 distinct recipients of sinus surgery (either balloon ostial dilation or FESS) for a total of $2,382,366 in professional services expenditures. Objective: This study …


Estrogen, Obesity, And Anticoagulant Protein S Contribute To Thrombosis In Mice, Alaina Guilbeau, Manoj Kumar, Laurent Mosnier, Rinku Majumder Oct 2022

Estrogen, Obesity, And Anticoagulant Protein S Contribute To Thrombosis In Mice, Alaina Guilbeau, Manoj Kumar, Laurent Mosnier, Rinku Majumder

Medical Student Research Poster Symposium

Protein S (PS) is an anticoagulant molecule present in humans and mice. Protein S binds and inhibits coagulation Factor IXa to control thrombin generation1 . Protein S is imperative for normal hemostasis and the prevention of life-threatening thrombotic events, as demonstrated by numerous studies of patients with PS deficiency2,3,4. Pregnant women5 and women who use estrogen-containing birth control pills 6 have lower levels of PS. Thus, it is postulated that estrogen downregulates PS expression in human. Because estrogen is synthesized by aromatase, which is highly expressed in adipose tissue7 , we expected that PS will be downregulated in obese mice …


A Case Of Cryptococcal Meningoencephalitis In An Immunocompetent Patient With Chiari I Malformation, Shreya Gunda, Victoria Silver, Kimiknu Mentore, Lauren Nunez Oct 2022

A Case Of Cryptococcal Meningoencephalitis In An Immunocompetent Patient With Chiari I Malformation, Shreya Gunda, Victoria Silver, Kimiknu Mentore, Lauren Nunez

Medical Student Research Poster Symposium

Over 90% of cases of cryptococcal meningoencephalitis present in immunocompromised patients, with the majority of those being in patients with AIDS. However, this infection can also occur in other immunocompromised states, such as steroid use, malignancy, rheumatologic diseases, and use of immunosuppressive medications. Delay in diagnosis can often lead to rapid neurological deterioration and mortality. We present a case of a young, otherwise immunocompetent patient, with history of Chiari I malformation and recent COVID-19 infection, found to have cryptococcal meningitis. The patient presented with syncope following two weeks of headaches, generalized body aches and weakness after COVID-19 diagnosis, and was …


Manual Vacuum Aspiration: Familiarity And Comfort Among Obgyn Physicians At Louisiana State University, Alexis Hernandez, Stacey Scheib Oct 2022

Manual Vacuum Aspiration: Familiarity And Comfort Among Obgyn Physicians At Louisiana State University, Alexis Hernandez, Stacey Scheib

Medical Student Research Poster Symposium

Background: Manual vacuum aspiration (MVA) uses a hand-held aspirator to generate a vacuum to aspirate uterine contents for management of early pregnancy loss or elective abortion prior to 12 weeks gestation. According to the American College of Obstetricians and Gynecologists, MVA is a safe, costsaving procedure that promotes patient comfort, convenience, and privacy. Despite the advantages of this procedure, it is often overlooked in favor of electric suction or dilation and curettage, more extensive procedures that are associated with increased cost and post-procedural pain and bleeding. The goal of this study is to assess the attitudes, familiarity, and comfort towards …


Prospective Observational Registry Study Of Myriad™ Matrix And Myriad™ Morcells In Soft Tissue Reconstruction, Tyler Hernandez, Cameron Fontenot, Cayley Leblanc, Paige Deville, Frank Lau, Alison Smith Oct 2022

Prospective Observational Registry Study Of Myriad™ Matrix And Myriad™ Morcells In Soft Tissue Reconstruction, Tyler Hernandez, Cameron Fontenot, Cayley Leblanc, Paige Deville, Frank Lau, Alison Smith

Medical Student Research Poster Symposium

Soft tissue reconstruction is a procedure that is fundamental to the practice of surgery. Due to the paramount importance of soft tissue repair, the need to improve this procedure through the use of modernized technologies is ever-present. Myriad Matrix is an intact extracellular matrix (ECM) that is available in a 3-layer or a 5-layer configuration. It is derived from ovine (sheep) forestomach tissue and retains the innate biological structure of the native ECM-associated macromolecules, including elastin, fibronectin, glycosaminoglycans, and laminin. When rehydrated with wound exudate or sterile saline, Myriad Matrix transforms into a malleable and compliant sheet that naturally incorporates …


Ophthalmology Consult Order: “Rule Out Open Globe Injury, Ellen Ingram, Matthew Williams, Kevin Kirchner Oct 2022

Ophthalmology Consult Order: “Rule Out Open Globe Injury, Ellen Ingram, Matthew Williams, Kevin Kirchner

Medical Student Research Poster Symposium

Out of traumatic eye injuries, open globe injuries are associated with the highest patient morbidity. Computed tomography (CT) imaging of the orbits is routinely used by the emergency department physician during workup of traumatic eye injuries. Positive CT findings reliably indicate penetration of the globe with a specificity up to 98% [1]. However, studies have consistently shown that CT imaging fails to diagnose approximately 30% of open globe injuries [1,2]. Therefore, a negative CT scan does not definitively rule out an open globe. There are no defined exam parameters that have been established as reliable indicators for open globe injuries …


Risk Of Malignancy Following Radiofrequency Ablation Of Thyroid Nodules, Peter P. Issa, M Omar, C P. Issa, Y Buti, M Hussein, M Aboueisha, A Abdelhady, M Shama, G S. Lee, E Toraih, Emad Kandil Oct 2022

Risk Of Malignancy Following Radiofrequency Ablation Of Thyroid Nodules, Peter P. Issa, M Omar, C P. Issa, Y Buti, M Hussein, M Aboueisha, A Abdelhady, M Shama, G S. Lee, E Toraih, Emad Kandil

Medical Student Research Poster Symposium

Radiofrequency ablation (RFA) is a safe and effective treatment of symptomatic benign thyroid nodules. However, some publications have cautioned against the use of RFA in Bethesda III, IV, and V thyroid nodules due to risk of developing follicular thyroid cancer. Unfortunately, these studies lack in statistical power due to small sample size. We aim to investigate the pathological changes following RFA of Bethesda III, IV, and V thyroid nodules. Patients treated by RFA with pre-operative and post-operative fine needle aspiration (FNA) were included. Nondiagnostic nodules were subsequently subjected to ThyGeNEXT and ThyraMIR testing. The FNA results following RFA were compared …


Solid Organ Pseudoaneurysms In Patients With High-Grade Traumatic Injuries: A Case Series, Shivani Jain, Harrison Travis, Meredyth Berard, Alexis Scheurermann, Alison A. Smith Oct 2022

Solid Organ Pseudoaneurysms In Patients With High-Grade Traumatic Injuries: A Case Series, Shivani Jain, Harrison Travis, Meredyth Berard, Alexis Scheurermann, Alison A. Smith

Medical Student Research Poster Symposium

Objectives: Blunt abdominal trauma affects 25% of all patients admitted with traumatic injuries. Although relatively rare (occurring in 2-10% of cases of solid organ injury), the development of solid organ (splenic, hepatic, or renal) pseudoaneurysms (PSA), particularly after initial imaging, can pose a significant threat to patients. If untreated, these PSAs may rupture and lead to lifethreatening hemorrhage. Despite this risk, the use of follow-up imaging after initial CT for blunt abdominal trauma remains controversial and has not been widely embraced. This case series shares experiences at two hospitals, a level 1 and level 2 trauma center, with 47 cases …


Understanding The Factors Associated With Us Dermatology Resident Trainees’ Diagnostic Confidence And Skill For Skin Of Color Pathology, Alissa Jeanfreau, Kaylin Beiter, Deborah Hilton Oct 2022

Understanding The Factors Associated With Us Dermatology Resident Trainees’ Diagnostic Confidence And Skill For Skin Of Color Pathology, Alissa Jeanfreau, Kaylin Beiter, Deborah Hilton

Medical Student Research Poster Symposium

Inequities in dermatologic health outcomes exist at every level of care delivery including disease prevention, screening, diagnosis, and treatment. Despite relatively lower incidence of skin cancer, African Americans are diagnosed at later stages with greater degrees of lymph node involvement. This has been shown to lead to disproportionate mortality when compared to lighter skinned individuals. In addition, frequently used medical education materials have a significantly smaller percentage of skin of color images as compared to lighter skin. Studies have subsequently identified greater visual diagnostic accuracy of skin conditions in lighter skin than in darker skin by U.S medical students. One …


Late Onset Immune Reconstitution Inflammatory Syndrome Presentingas Infectious Meningitis, Yasmeen Kawji, Jacob A. Nelson, Carl J. Griffin, Alexander G. Hosse Oct 2022

Late Onset Immune Reconstitution Inflammatory Syndrome Presentingas Infectious Meningitis, Yasmeen Kawji, Jacob A. Nelson, Carl J. Griffin, Alexander G. Hosse

Medical Student Research Poster Symposium

A 35-year-old African American male with no significant past medical history presented with generalized weakness, fatigue, cough, progressive 50-pound weight loss in the last 2 months, frontal headache, neck stiffness, and blurry vision. Workup revealed fever, sinus tachycardia, positive HIV screening, and multiple electrolyte abnormalities. There were negative/insignificant results on chest, lumbar spine, and head imaging. HIV viral load was 784,000; CD4 count was 4. Blood cultures grew yeast. Lumbar puncture revealed an opening pressure of 50 mmHg, WBC 2, protein 18, glucose 22, and a CSF panel positive for cryptococcus. The patient was initiated on induction therapy with AmBisome …


Development Of Genetic Strategies To Treat Vision Loss In Usher Syndrome Type 1c (Ush1c), Dongjoon (Jason) Kim, Inga Kristaponyte, Bhagwat Alapure, Katelyn Robillard, Wadih Zein, Robert Koenekoop, Maria Reinoso, Jennifer J. Lentz Oct 2022

Development Of Genetic Strategies To Treat Vision Loss In Usher Syndrome Type 1c (Ush1c), Dongjoon (Jason) Kim, Inga Kristaponyte, Bhagwat Alapure, Katelyn Robillard, Wadih Zein, Robert Koenekoop, Maria Reinoso, Jennifer J. Lentz

Medical Student Research Poster Symposium

Background: Usher Syndrome (Usher) is the most common genetic cause of deaf-blindness, characterized by the loss of hearing, vestibular function, and vision. Three clinical types (USH1- 3) and 10 genes are associated with the disease. USH1 is the most severe with congenital severeprofound sensorineural hearing loss and vestibular areflexia, and childhood onset of retinitis pigmentosa. Mutations in the USH1C gene account for 6-15% USH1, however USH1C c.216G>A (216A) accounts for nearly all USH1 cases in the Acadian populations in U.S. and Canada. The 216A splicing mutation results in a truncated harmonin protein, and photoreceptor and cochlear hair cell dysfunction. …


Complications Of Brucella Infection In Previously Healthy Adult Male, Caila D. Knighton, Sarah C. Corley, Hope E. Oddo Moise Oct 2022

Complications Of Brucella Infection In Previously Healthy Adult Male, Caila D. Knighton, Sarah C. Corley, Hope E. Oddo Moise

Medical Student Research Poster Symposium

A 36-year-old Mexican immigrant male presented to an outside hospital after being found down in a sugarcane field. On initial presentation he was febrile to 104.7, hypotensive with a GCS of 3. He soon had an episode of emesis, with new onset seizure activity. He was refractory to fluid resuscitation, started on pressors and intubated before being transferred to UMC. Blood cultures drawn and returned positive for Brucella. While being one of the most common zoonotic diseases worldwide, Brucella infections are reported 100 to 200 times annually in the United States. Typically, Brucellosis presents with malaise, fever, night sweats and …


Measuring Muscle Tissue Trauma In Murine And In-Vivo Models, Tara Korbal, Jennifer Simkin, Jessica Rivera Oct 2022

Measuring Muscle Tissue Trauma In Murine And In-Vivo Models, Tara Korbal, Jennifer Simkin, Jessica Rivera

Medical Student Research Poster Symposium

Introduction: Extremity trauma involving bone and soft tissue injury is prone to complications such as poor tissue healing, wound dehiscence, wound infection, fracture related infection, and fracture nonunion. Increased understanding of how the local traumatized tissue affects healing is needed to reduce frequency of complications. The aim of this research is to establish methods of measuring muscle tissue trauma using discarded muscle tissue. These methods are first optimized in a murine model. Methods: After 4 mice were euthanized, we dissected out the anterior compartment of the lower extremity. We also took the tibia because it proved too difficult to remove …


Interhospital Transfers Do Not Affect Outcomes Of Necrotizing Soft Tissue Infections, Casey Landreneau, Rachel Saravia, Sarah Stobbs, Jonathan Schoen, Alison Smith Oct 2022

Interhospital Transfers Do Not Affect Outcomes Of Necrotizing Soft Tissue Infections, Casey Landreneau, Rachel Saravia, Sarah Stobbs, Jonathan Schoen, Alison Smith

Medical Student Research Poster Symposium

BACKGROUND: Necrotizing soft tissue infection (NSTI) is a rapidly progressive disease with high morbidity and mortality that requires extensive care and multifaceted rehabilitation typically found at a tertiary facility. However, many patients initially present to smaller outside hospitals with less resources and require inter-hospital transfer during their treatment. OBJECTIVE: The aim of in this study was to further characterize the overall prognosis of subjects with NSTI transferred to a higher echelon of care and to determine if there is a clinical difference in outcomes based on transfer status. METHODS: We conducted a retrospective, multi-institutional review of subjects admitted for NSTI …


Minority Stress Among Lgbtq Smokers In The Deep South: A Mixed Methods Study, Mirandy S. Li, Holly Mayeaux, Jackson Fritz, Gabrielle Gonzalez, Stephen Phillippi, Qingzhao Yu, Edward Trapido, Michael Celestin, Tung-Sung Tseng Oct 2022

Minority Stress Among Lgbtq Smokers In The Deep South: A Mixed Methods Study, Mirandy S. Li, Holly Mayeaux, Jackson Fritz, Gabrielle Gonzalez, Stephen Phillippi, Qingzhao Yu, Edward Trapido, Michael Celestin, Tung-Sung Tseng

Medical Student Research Poster Symposium

Background: Lesbian, Gay, Bisexual, Transgender, and Queer (LGBTQ) individuals face higher levels of stress than the general population in the form of minority stress, defined as discriminatory, stigmatizing, and victimizing experiences. Minority stress has been posited as a cause for LGBTQ individuals to smoke as a coping mechanism, leading to higher than average rates of smoking in this population. The Deep South states of Louisiana, Mississippi, Alabama, Georgia, and South Carolina represent an area with both high levels of minority stress and smoking. Therefore, the objective of this study was to elucidate how minority stress influences smoking among LGBTQ smokers …


Impact Of Mean Arterial Blood Pressure Compliance On Neurologic Outcomein Patients With Traumatic Spinal Cord Injuries, Brock D. Lingle, Zohaib Lakhani, Emily Noel, Ina Du, Alison Smith Oct 2022

Impact Of Mean Arterial Blood Pressure Compliance On Neurologic Outcomein Patients With Traumatic Spinal Cord Injuries, Brock D. Lingle, Zohaib Lakhani, Emily Noel, Ina Du, Alison Smith

Medical Student Research Poster Symposium

No abstract provided.


Evaluating Social Vulnerability Impact On Care & Prognosis Of Head & Neck-Nervous System Cancers In The Us, Salim C. Lutfallah, David J. Fel-Zhang, Daniel C. Chelius, Jill N. D'Souza, Jeffery C. Rastatter, Anthony M. Sheyn Oct 2022

Evaluating Social Vulnerability Impact On Care & Prognosis Of Head & Neck-Nervous System Cancers In The Us, Salim C. Lutfallah, David J. Fel-Zhang, Daniel C. Chelius, Jill N. D'Souza, Jeffery C. Rastatter, Anthony M. Sheyn

Medical Student Research Poster Symposium

Introduction In the current literature, the association between social determinants of health (SDH) and head & neck-nervous system cancer (HNNsC) is limited by the narrow scope of SDH assessed and the broad classifications of HNNsC. Our study utilizes the CDC-Social Vulnerability Index (SVI) to assess both the individual and collective impact of four social determinant themes on various HNNsC in US adults. Methods This retrospective cohort study utilized the SEER database to evaluate 116,373 adult patients from 1975-2017 who presented with various types of HNNsC. Patients were assigned SVI scores based on county-of-residence at the time of diagnosis, encompassing total …


Exploring The Paracrine Potential Of Peri-Articular Muscle In Response To Knee Osteoarthritis Severity, Davis Martin, Tara Soria, Jose A. Cruz-Ayala, Mary C. Gatterer, Vinod Dasa, Luis Marrero Oct 2022

Exploring The Paracrine Potential Of Peri-Articular Muscle In Response To Knee Osteoarthritis Severity, Davis Martin, Tara Soria, Jose A. Cruz-Ayala, Mary C. Gatterer, Vinod Dasa, Luis Marrero

Medical Student Research Poster Symposium

Skeletal muscles such as the Articularis genu (AG) undergo disuse-mediated myofiber type redistribution, atrophy, and fibrosis attributable to knee osteoarthritis (KOA). Although peri-articular musculature can differentially secrete over 600 myokines in response to exercise or arthropathy, its paracrine influence on the symptomatic severity of KOA is largely underexplored. Myostatin (Mst) and irisin myokines have been of particular interest in cardiac research for their effective modulation of hypertrophic damage and endomysial fibrosis in cardiomyopathy, which are also hallmark structural features of the KOA musculature that can impair joint function. Measuring intra-articular concentrations of Mst and irisin in the synovial fluid (SF) …


Radiance 2: Reducing Delays In Endometrial Cancer Care Gynecologic Oncology Care, Jessica Anderson, Kyla Maupin, Hannah Sibley, Nicole Catalano, Rebecca Maitski, Navya Nair, Tara Castellano, Andrew G. Chapple, Amelia Jernigan Oct 2022

Radiance 2: Reducing Delays In Endometrial Cancer Care Gynecologic Oncology Care, Jessica Anderson, Kyla Maupin, Hannah Sibley, Nicole Catalano, Rebecca Maitski, Navya Nair, Tara Castellano, Andrew G. Chapple, Amelia Jernigan

Medical Student Research Poster Symposium

Objective: We aimed to identify actionable delays in care that for women with endometrial cancer (EC) from the time of gynecologic oncology referral through adjuvant therapy. Methods: A multicenter, IRB-approved retrospective chart review was performed. Women diagnosed with Stage I-IV endometrial cancer from 2013 to 2022 were included. Demographic, pathologic, treatment, and survival data were collected. Symptom duration and key appointment, procedure, or result dates were recorded. Time frames between key events were calculated. Timed events were censored if there was insufficient data to make a calculation. Categorical covariates were summarized with counts and percentages; continuous variables were summarized via …


Pulmonary Pseudoaneurysm Due To Penetrating Thoracic Trauma, Michael Mcmahon, Andrew Ea, Hector Ferral Oct 2022

Pulmonary Pseudoaneurysm Due To Penetrating Thoracic Trauma, Michael Mcmahon, Andrew Ea, Hector Ferral

Medical Student Research Poster Symposium

Background: Pulmonary artery pseudoaneurysm (PAP) is a rare but potentially lethal condition. Acquired PAPs are most commonly caused by iatrogenic trauma and infectious disease. Infectious causes include bacterial endocarditis, tuberculosis, mucormycosis, and pyogenic infection. Traumatic PAPs can be caused iatrogenically by pulmonary artery catheterization. Very few cases have been described of patients developing PAP as a complication of a gunshot wound to the chest. Radiologic findings of PAP include hilar enlargement or a new focal lung mass on chest radiograph. CT angiography shows saccular or fusiform areas of dilatation with homogenous contrast filling which occurs simultaneously with the pulmonary artery. …


Disparities Associated With Total Joint Arthroplasty Transfusion And Complication Rates, Shelby Meckstroth, Andrew Chapple, Peter Krause, Deryk Jones, Lauren Leslie, Vinod Dasa Oct 2022

Disparities Associated With Total Joint Arthroplasty Transfusion And Complication Rates, Shelby Meckstroth, Andrew Chapple, Peter Krause, Deryk Jones, Lauren Leslie, Vinod Dasa

Medical Student Research Poster Symposium

Introduction: Complications such as infection, readmission and mortality occur with transfusion after total joint arthroplasty (TJA). Certain populations, including females, Black patients, patients with public insurance and older adults have higher risks of transfusion. Recently, there has been a decline in transfusion rates and a greater emphasis on equity in medicine. Therefore, our study sought to understand whether disparities in transfusion rates still exist and what variables influence transfusion rates over time. Methods: We used the Ochsner Healthcare Network database to identify TJA patients from 2013 to 2021. Fisher exact and Wilcoxon rank sum tests were used to compare categorical …


Comparing Patient Mobility Pre- And Post Amp Implementation Acrossmedical 5, 4mnt, Stu, And Neurology Units At Our Lady Of The Lake Regional Medical Center, Jayne Mora, Evan Sinnathamby, Hannah Robinson, Logan Arceneaux, Alyse Hollis, Hunter Collins, Micah Klumpp, Christopher Thomas Oct 2022

Comparing Patient Mobility Pre- And Post Amp Implementation Acrossmedical 5, 4mnt, Stu, And Neurology Units At Our Lady Of The Lake Regional Medical Center, Jayne Mora, Evan Sinnathamby, Hannah Robinson, Logan Arceneaux, Alyse Hollis, Hunter Collins, Micah Klumpp, Christopher Thomas

Medical Student Research Poster Symposium

BACKGROUND: Decreased mobility during hospitalization and recovery is a major contributor to poor healthcare outcomes and increased lengths of stay. Neglecting patient mobility also carries risks including, but not limited to, an increased likelihood of falling, difficulties performing basic activities, pressure injuries, and venous thromboembolism. Prevention of hospitalacquired loss of function is therefore essential in improving patient care and the healing process. Our Lady of the Lake Regional Medical Center was chosen to participate in a proposed project in association with Johns Hopkins to evaluate the implementation and impact of a transdisciplinary and multifaceted mobility program known as Activity and …


Differences In Accessibility To Program Directors Indicates A Potential Greater Burden Upon Female Program Directors, Tram Ngo, Kaylin Beiter, Erich Conrad, Erika Rajo Oct 2022

Differences In Accessibility To Program Directors Indicates A Potential Greater Burden Upon Female Program Directors, Tram Ngo, Kaylin Beiter, Erich Conrad, Erika Rajo

Medical Student Research Poster Symposium

Introduction: The COVID-19 pandemic and subsequent limitations on in-person interviews and away rotations have necessitated residency program directors and prospective applicants alike to rely disproportionately upon electronic means of communication relative to years past. Program directors (PDs) play a key role in providing information about their program to applicants, however it is unknown how accessible PDs are to prospective applicants. The objective of this study was to explore differences in accessibility to PDs via their use of individual, general (programmatic), or administrative-assistant email addresses in the FREIDA database. Methods: The FRIEDA database was queried for all US-based internal medicine programs. …