Medicine and Health Sciences Commons^™

Emergent Potential Of The Terahertz Cmos Microprocessor, F. Matthew Mihelic

Faculty Publications

The terahertz speed CMOS microprocessor that has been designed by Averoses Incorporated (US11063118B1) utilizes nano-vacuum tube elements with plasma interconnect of those elements, and has the capability to emit, detect, conduct, and analyze electromagnetic signals in the terahertz range. Nano-vacuum tube systems are resistant to ionizing radiation and to high temperatures, and there are emergent potentials of such systems beyond the obvious speed-up of data processing. Such a microprocessor can provide a platform for compact terahertz spectroscopy, especially for organic molecules, and this can also include DNA sequencing and DNA fingerprinting. Another emergent quality of such a system is that, …

A Quantum Logic Gate In The Dna Deoxyribose Moiety, F. Matthew Mihelic

Faculty Publications

The deoxyribose moiety of a nucleotide in the DNA molecule can act as a quantumlogic gate, in which the enantiomeric shift between the C2-endo and C3-endo conformations of each nucleotide, occurs within a logically and thermodynamically reversible situation of electron spin qubits, that are coherently held within the topologically insulating DNA crystalline nanostructure, and that are coherently conducted along the delocalized electrons of the pi-stacked nucleotide base pairs. The enantiomeric symmetry between the C2-endo and C3-endo conformations is logically and thermodynamically reversible because it functions as a symmetry-breaking Szilard engine that is effectively built out of the physicality of the …

The Noloco Strategy For Essential Hypertension, F. Matthew Mihelic Md

Faculty Publications

Ninety-nine percent of all “essential” hypertension can be controlled by using the NoLoCo strategy, without causing any significant side-effects and without an increase in insulin resistance. NoLoCo stands for Norvasc (amlodipine), Lozol (indapamide), and Cozaar (losartan), but the medicines are considered and used in reverse order.

Updates In The Pharmacologic Prophylaxis And Treatment Of Invasive Candidiasis In The Pediatric And Neonatal Intensive Care Units, James Hunter Fly, Seerat Kapoor, Kelly Bobo, Jeremy S. Stultz

Faculty Publications

Purpose of review The goal of this review was to provide an update on the prevention and treatment options for invasive candidiasis (IC) in the neonatal intensive care unit (NICU) and pediatric intensive care unit (PICU).

Recent findings Studies have further validated the use of fluconazole for IC prophylaxis among high-risk patients in the NICU. It remains unclear if prophylaxis leads to resistance development and the ideal dosage regimen is still not clear. Recent studies have been published comparing caspofungin and micafungin to amphotericin B and illustrated similar efficacy outcomes in the NICU. Micafungin now has approval from the United …

Implementation Of The Cognitive Apprenticeship Model For Enhancement Of Advanced Searching Skills In A Pharmacy Academia Rotation: Appendices 1-4, Hilary Jasmin Msis, Kenneth Hohmeier Pharmd, Christina Spivey Pharmd, Phd

Faculty Publications

No abstract provided.

Implications Of The Quantum Dna Model For Information Sciences, F. Matthew Mihelic

Faculty Publications

The DNA molecule can be modeled as a quantum logic processor, and this model has been supported by pilot research that experimentally demonstrated non-local communication between cells in separated cell cultures. This modeling and pilot research have important implications for information sciences, providing a potential architecture for quantum computing that operates at room temperature and is scalable to millions of qubits, and including the potential for an entanglement communication system based upon the quantum DNA architecture. Such a system could be used to provide non-local quantum key distribution that could not be blocked by any shielding or water depth, would …

Magnetic Vector Potential Manipulation Of Majorana Fermions In Dna Quantum Logic, F. Matthew Mihelic

Faculty Publications

In the quantum logic of the DNA molecule, electrons are held and conducted coherently as spinless Cooper pairs and are shielded from electromagnetic energy by a Faraday cage effect of the double lipid bilayer of the nuclear membrane. The magnetic vector potential generated by cellular depolarization can synchronize logical activity in portions of the DNA molecule by affecting spin directions of appropriately oriented spinless electrons via the Aharonov-Bohm effect, but is not blocked by that Faraday cage effect. Within the logically and thermodynamically reversible chiral enantiomeric symmetry of the deoxyribose moieties the decoherent transition of Cooper pair to Dirac pair …

2020 County Health Rankings Tennessee Data And Updated Substance Abuse 2005-2019, Kelsey L. Grabeel, Jenny Moore

Faculty Publications

No abstract provided.

How One Library’S Location Change Impacted Health Information Requests: Comparing Zip Codes And Health Disparities To Inform Library Services: Data Files, David Petersen, Martha Earl, Cameron Watson, Kelsey Grabeel

Faculty Publications

No abstract provided.

Why Is Family Medicine Different?, F. Matthew Mihelic, Gregory H. Blake

Faculty Publications

An understanding of the role and function of Family Medicine in the healthcare system can provide important insights for Enterprise Architecture. It is often stated that the thought process utilized by Family Medicine physicians is different from that of specialty physicians, but heretofore there has been little or no analysis of what that difference is. This article examines that difference from the perspective of the complex adaptive system that is healthcare today, and shows how it is that Family Medicine physicians perform the vital function of decreasing the entropy or disorder in the patient care system via decision loops, as …

Back Of The Envelope Calculations Regarding Alexandrov, Et Al. 2009, F. Matthew Mihelic

Faculty Publications

The paper entitled “DNA Breathing Dynamics in the Presence of a Terahertz Field” written by Alexandrov, Gelev, Bishop, Usheva, and Rasmussen that was posted on the Physics ArXiv on October 28, 2009, dealt with the effects of terahertz electromagnetic radiation on the DNA molecule. Figure 4 of the paper indicates that a segment of DNA that is between 60 and 70 base pairs in length will develop a “bubble” (i.e. separation of the hydrogen bonds between base pairs) at a location of about 45 base pairs, when exposed to 2 THz electromagnetic radiation for a time period of at least …

Overcoming Erroneous Confirmation Bias, F. Matthew Mihelic

Faculty Publications

This paper will explore strategy for overcoming erroneous confirmation bias within the context of generalist versus specialist function as described in the paper entitled “Information Fusion and Quantum Logic in Family Medicine”.

Information Fusion And Quantum Logic In Family Medicine, F. Matthew Mihelic

Faculty Publications

A time-tested model for information fusion and analysis is provided by Family Medicine. Family Medicine is a discipline that operates in the realms of botJ1 technical and social sciences to analyze massive amounts of information from mulriple sources in order to make decisions that bring about tJie integration and coordination of interdisciplinary interventions involving scientific, psychological, and social aspects of medical care. This generalist function serves to lower the organizational entropy of complex systems and thereby improve efficiency while reducing ilie risk of catastrophic failure. Simply bringing a group of specialists together in one place does not bring about the …

The Changing Role Of Physicians In Disaster Management And Hospital Incident Command, F. Matthew Mihelic, M. David Stockton, Stephen A. Cole, Gregory H. Blake

Faculty Publications

Recent changes in governmental policy toward disaster medicine and hospital incident command foreshadow a significant change in the role that physicians will play in disaster preparedness and response. The distinct discipline of Disaster Medicine has received authoritative recognition and promotion in the recent Homeland Security Presidential Directive 21, and recently established guidelines for incident command within hospitals have included a new position designated as “Medical/Technical Specialist(s)” that will assist the Incident Commander in disaster-related decision-making. This is a multidisciplinary position, and its functions can be filled by one or more individuals. As physician training and competency in Disaster Medicine increases, …

A Relationship Between Us Healthcare Worker Smallpox Vaccination Rates In 2003 And Presidential Election Results In 2004, F. Matthew Mihelic, David G. Schultz Jr., Melinda R. Mihelic

Faculty Publications

A statistical relationship exists between state per capita smallpox vaccination rates of healthcare workers in 2003 and state presidential election results in 2004. The potential implications of political influence on national biosecurity decision making are discussed.

J.T.: A Case Of Mitral Valve Prolapse, F. Matthew Mihelic

Faculty Publications

No abstract provided.

Locus Of Control, Knowledge Of Ethics, And Perceived Ethicality As Influenced By An Authority Figure, F. Matthew Mihelic, William G. Connolly

Faculty Publications

The present study investigated the relationship between a subject's locus of control, knowledge of psychological ethical research principles, and perceived ethicality of a psychological research proposal as influenced by an authority figure. Subjects were asked to judge the ethicality of a research proposal, which half were led to believe had been previously deemed unethical by an authority figure. No mention was made of the authority figure's viewpoint to the other subjects. The major finding was that the variability in ratings in ethicality of the research proposal tended to diminished from the no mention to the rejection manipulation in those of …