Medicine and Health Sciences Commons^™

Flight Physician - December, 2008, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A sixteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Hepatoma Cells Up-Regulate Expression Of Programmed Cell Death-1 On T Cells, Ji Chen, Gui-Qiang Wang

Pharmacology and Toxicology Faculty Publications

AIM: To investigate the effect of hepatoma cells on up-regulation of programmed cell death-1 (PD-1), and the function of PD-1 on T cells. METHODS: HepG2 or HepG2.2.1.5 cells were co-cultured with a lymphoma cell line-Jurkat cells. PD-1 expression was detected by flow cytometry. IL-2, INF-γ and IL-10 in culture supernatant were detected by enzyme-linked immunosorbent assay (ELISA). Cytotoxic action of T cells was determined by MTT reduction assay-direct mononuclear cell cytotoxicity assay. RESULTS: The PD-1 expression on Jurkat cells increased by 16.17% ± 2.5% and 17.43% ± 2.2% after HepG2 or HepG2.2.1.5 cells were co-cultured for 48 h. The levels …

Neuroendocrine Peptides Neuropeptide-Y (Npy) And Peptide-Yy (Pyy) Suppress Cl- Secretion And K+ Secretion In Guinea Pig Distal Colon Through Action At Y2-Receptors, Susan T. Halm, Jin Zhang, Dan R. Halm

Neuroscience, Cell Biology & Physiology Faculty Publications

Electrogenic Cl^– and K⁺ secretion in isolated mucosa from guinea pig distal colon measured as short-circuit current (I_sc) and transepithelial conductance (G_t) were stimulated by epinephrine (epi), prostaglandin-E₂ (PGE₂) and carbachol (CCh). neuropeptide-Y (NPY) and peptide-YY (PYY) inhibited by 60% Cl^– secretion activated by either PGE₂ or PGE₂+CCh with EC₅₀’s of 16nM and 6nM, respectively. Neither peptide markedly inhibited the transient component of the PGE₂+CCh response. Immunoreactivity (IR) for NPY was present in enteric ganglia and in proximity with crypts. Basolateral membranes of …

Viral Vectors In The Research Laboratory: Just How Safe Are They?, Dawn P. Wooley, Kimberly Kay Morris, Robert Mcrae, John C. Trefry

Neuroscience, Cell Biology & Physiology Faculty Publications

No abstract provided.

Emerging Issues In Forensic Dna Profiling: Databases And Advisory Boards, Dan E. Krane

Biological Sciences Faculty Publications

No abstract provided.

Shifts In Southern Wisconsin Forest Canopy And Understory Richness, Composition, And Heterogeneity, David A. Rogers, Thomas P. Rooney, Daniel Olson, Donald M. Waller

Biological Sciences Faculty Publications

We resurveyed the under- and overstory species composition of 94 upland forest stands in southern Wisconsin in 2002–2004 to assess shifts in canopy and understory richness, composition, and heterogeneity relative to the original surveys in 1949–1950. The canopy has shifted from mostly oaks (Quercus spp.) toward more mesic and shade-tolerant trees (primarily Acer spp.). Oak-dominated early-successional stands and those on coarse, nutrient-poor soils changed the most in canopy composition. Understories at most sites (80%) lost native species, with mean species density declining 25% at the 1-m² scale and 23.1% at the 20-m² scale. Woody species have increased …

Healing Young People Thru Empowerment (H.Y.P.E.): A Hip-Hop Therapy Program For Black Adolescent Males, Adia B. Mcclellan

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Treating Black adolescent males with disruptive behavior disorders can be challenging for psychologists and other mental health professionals The negative perception of this group within society, as well as the absence of clinical training exploring issues pertinent to Black adolescent males, among other things, may hinder a professional’s ability to effectively work with this population. This doctoral project discussed the research in several areas currently pertinent to Black adolescent males, as well as factors that have historically been oppressive to Black Americans. It then describes several DSM-IV-TR diagnoses and legal classifications associated with Disruptive Behavior Disorders. In addition, research analyzing …

Vital Signs, Fall 2008, Boonshoft School Of Medicine

Vital Signs

A fifty-five page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, and more.

Preterm Birth Rates In Pregnant Women With Sexually Transmitted Infections: Cincinnati Public Health Centers 2005 And 2006 Deliveries, Elizabeth Singhoffer

Master of Public Health Program Student Publications

Objective: To evaluate the differences in prenatal maternal infections in women served by the City of Cincinnati health centers that have or have not had a preterm birth.

Methods: A retrospective and observational study of medical records of 738 patients seen at the City of Cincinnati health centers, who delivered in the years of 2005 and 2006. The usable data resulted in 668 total subjects. Data collected included types of health care visits prior to index pregnancy, if preconception/ reproductive health care was discussed, demographics, gestational age at first prenatal visit and at delivery, insurance at first prenatal visit and …

Evaluating Patient Compliance: Effect Of Appointment Reminder Systems On Attendance, Jacquelyn D. Phillips

Master of Public Health Program Student Publications

Currently, rising health care cost is an important topic on many agendas and platforms. In 2007, health care spending in the United States reached $2.3 trillion, and was projected to reach $3 trillion in 2011 (NCHC, 2007). Increasing health care cost is in direct relationship with the rise in the ageing population, chronic illness, and the uninsured lower socioeconomic population as well. The research on medical compliance and attendance (missed/kept appointment) behavior is an important area to explore because it is critical for all aspects of successful treatment, disease prevention, and health promotions that have direct correlation with health care …

Flight Physician - July, 2008, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A sixteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

What Are The Individual Preparations For Children With Special Health Care Needs In The Event Of An Emergency?, Karen Sue Barcelo

Master of Public Health Program Student Publications

Children with special health care needs are one of the most vulnerable groups in the event of an emergency. Natural and manmade disasters or emergency events occur on a daily basis. Government agencies, schools and day care centers have begun developing emergency disaster plans; fewer plans have been developed for children with special needs. One explanation for the lack of specific planning for children is that agencies may believe that plans for adults are not different from plans for children. There may be many reasons why parents who have children with special needs may not have an emergency plan in …

The Ohio Substance Abuse Monitoring Network: Overview And Recent Drug Trends, Robert G. Carlson, Russel S. Falck

Population and Public Health Sciences Faculty Publications

No abstract provided.

Ohio Academy Of Medical History Annual Meeting Program, April 5, 2008, Ohio Academy Of Medical History

Annual Conference Programs

This tri-fold program is from the annual review of the Ohio Academy of Medical History held on April 5, 2008 at the Dittrick Medical History Center in Cleveland, Ohio. The program details the events and presentations of the meeting.

Flight Physician - April, 2008, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A sixteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Screening Assay For Enzymes Involved In Pathophysiology Using Seldi-Tof Mass Spectrometr, Khalid M. Elased, Mariana Morris

Pharmacology and Toxicology Faculty Publications

The invention provides methods for quantifying enzymatic activity of an enzyme with a known substrate. The methods employ SELDI-TOF mass spectrometry, and are suitable, in particular, for assaying aspects of the renin-angiotensin system. The methods may be utilized to assess and/or monitor biological conditions associated with the renin-angiotensin system prior to the manifestation of known physiological and biomarkers for such conditions. The methods are suitable for analysis of pharmacological effectors of the renin-angiotensin system, and are particularly suitable for automation and high-throughput screening assay design.

Martin, Patricia Interview For The Miami Valley College Of Nursing And Health Oral History Project, Carol Holdcraft, Donna M. Curry, Anika Surrat, Patricia Martin

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Carol Holdcraft, Donna Miles Curry, and Anika Surrat interviewed Patricia Martin about the Wright State University College of Nursing and Health.

Soda: Seniors For Organ Donation Awareness “Increasing The Enrollment Of Senior Citizens (Age 65 Years And Older) In The Ohio Donor Registry”, Laurie L. Phillips

Master of Public Health Program Student Publications

Research Hypothesis: A targeted informational awareness program about organ and tissue donation to senior citizens (age >65 years) in Montgomery County, Ohio will produce an increase in the number of registered organ donors in the Ohio Donor Registry, hence, allowing more available organs for transplant for aging patients (50 years of age or older) in need across the region. Subsequently, another research objective is to identify and address underlying factors causing senior citizens to be the lowest number of registered donors in Montgomery County, Ohio, in fact, across the state. This information will assist in future public education efforts of …

Easterly, Linda Interview For The Miami Valley College Of Nursing And Health Oral History Project, Carol Holdcraft, Linda Easterly

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Carol Holdcraft interviewed Linda Easterly about the founding of the Wright State University College of Nursing and Health. In the interview, Easterly discusses her career and her decision to come to Wright State as a student with the College of Nursing and Health.

Water System Preparedness For Pandemic Influenza, Phil Van Atta

Master of Public Health Program Student Publications

This project involved an investigation of water utility preparedness and best practices for pandemic influenza. A pandemic could cause serious disruptions to the operations of critical infrastructure, including drinking water systems. These disruptions could be caused by staffing shortages, power disruptions, and shortages of chemicals and other supplies. Ensuring continuity of operations for drinking water systems is crucial to protect public health and safety, and to the economy of all communities. Literature searches, interviews, and a survey of Ohio water systems indicated that water systems in Ohio and across the United States are preparing for pandemic influenza. Pandemic influenza preparation …

Oxidative Stress And Cell Death In Osmotically Swollen Glial Cells, Crystal Elaine Stuckey

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Regulation of normal volume is an important aspect of cell homeostasis. Possible mechanisms which signal volume regulation are increasing the rate of reactive oxygen species (ROS) production and release of ATP for interaction with purinergic receptors. We examined whether an increase in ROS production during cell swelling also led to cell injury of C6 glioma cells. Cells were loaded with 5,6-carboxy-2,7-dihydrofluorscein diacetate (DCFDA) to fluoroscopically measure the rate of cellular ROS production and were perfused with phosphate-buffered saline solutions (PBS) containing 100 μM carbenoxolone to inhibit dye efflux. Cell death was determined cytometrically and by measuring the release of lactate …

The Public Health Implications Of Trafficking, Tami Ashbridge

Master of Public Health Program Student Publications

Trafficking in human beings is a serious and complex human rights issue. Trafficking for the purpose of sexual exploitation has grave public health implications. The vulnerability of women and children increases their risk of becoming victims of trafficking for the purposes of sexual exploitation. Review of the literature on this subject demonstrates a direct link between the trafficking of women and children for sexual exploitation and the prevalence of HIV/AIDS, STIs and Reproductive/Gynecological Issues, Mental Health, Violence, Abuse and Social Issues. This review supports the concept of human trafficking as a serious public health issue and the need for improved …

Emerging Trends In Cigarette Sales In Ohio During First Year Implementation Of The Smoking Ban, Megan Luse

Master of Public Health Program Student Publications

Objective: The Ohio smoking ban was passed by Ohio voters on November 7, 2006 and took effect on December 7, 2006. The reporting of violations to the Ohio smoking ban began on May 3, 2007 with the implementation of the civil penalties for the violations. The purpose of this study is to look at emerging trends in cigarette sales change from 2006 to 2007 for the 88 counties in Ohio following implementation of the smoking ban on December 7, 2006 based on geographical location, violation level, and tobacco production.

Methods: Data was obtained from Claritas for the 2006 aggregate expenditure …

Robotic Rectal Cancer Surgery, Minia Hellan, Joshua Ellenhorn, Alessio Pigazzi

Department of Surgery Faculty Publications

No abstract provided.

A Descriptive Study Of Parenting Styles, Parental Feeding Behaviors And Bmi Percentiles In School-Age Children And Adolescents, Stephanie Jane Smith

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The rising rate of obesity in the pediatric population has demanded further investigation from members of the health care community. Numerous exercise and nutrition programs have been developed to help combat the growing rate of obesity within the pediatric population but many lack the family-centered approach needed to achieve increased compliance with the prescribed plan of care. Both parenting styles and parental feeding behaviors have been shown to play a contributing role in the weight of children. According to previous research, the authoritarian parenting style often leads to an increased BMI in children. Research examining parental feeding behaviors indicates that …

Effects Of Sepsis On Nerve Evoked Responses, Kevin Richard Novak

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Sepsis and SIRS (systemic inflammatory response syndrome) have become two expensive and complicated problems seen in the intensive care unit (ICU). These two illnesses have been known to cause dysfunction with excitable tissues in the body. Encephalopathy, neuropathy, and myopathy are the three biggest. In this paper we discuss the development of an animal model of sepsis and the neurological complications sepsis brought about. Nerve conduction studies showed increased durations on compound muscle action potential, and decreased amplitude as well as increased duration and latency on sensory nerve action potentials. These results were not consistent with the two most common …

Effects Of Subcutaneous Postnatal Choline Supplementation On Hippocampus-Mediated Learning And Memory In Rat Pups, Jeremy Alan Moore

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The effects of postnatal injections of choline on the acquisition of two variants of eyeblink conditioning were examined in developing Long-Evans rat pups. Choline administration on postnatal days (PND) 15-27 was followed by evaluation of trace eyeblink conditioning (Experiment 1) and delay eyeblink conditioning (Experiment 2) on PND 28-29. The results of these experiments show that choline produced greater improvements in learning and memory during the trace condition than in the delay condition, presumably due to its effect on the hippocampus. Trace eyeblink conditioning relies heavily on an intact hippocampus but delay eyeblink conditioning does not, and it is understood …

Stress Reducing Effects Of Oxytocin In A Maternal Separation Paradigm, Keely Jane O'Connell

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This study compared the effects of centrally and peripherally administered oxytocin (OT) on HPA axis activity and the presence of both stress-induced active and passive behaviors in female guinea pig pups (Cavia porcellus) after 180-min of isolation . In Experiment 1, one dose of oxytocin (10μg/.2ml) was injected subcutaneously into the periphery. Plasma cortisol levels were reduced after 180-min of isolation and two passive behaviors, eye-closure and crouch, were reduced as well with the administration of oxytocin. In Experiment 2, two different doses (10μg/.2ml and 20μg/.2ml) were injected into the periphery with no significant results. In Experiment 3 one dose …