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Articles 151 - 180 of 185
Full-Text Articles in Medicine and Health Sciences
The Association Between Masticatory Performance, Oral Health Status, And Dental Prostheses In Adults At A Dental Hospital In Jakarta, Fakhrana Ariani Ayub, Farisza Gita, Nina Ariani
The Association Between Masticatory Performance, Oral Health Status, And Dental Prostheses In Adults At A Dental Hospital In Jakarta, Fakhrana Ariani Ayub, Farisza Gita, Nina Ariani
Journal of Dentistry Indonesia
Masticatory performance has been studied extensively in the past few decades. Age, gender, the number of teeth in occlusion, occlusal contact area, salivary flow, and neurophysiological deficits influence the masticatory process. The replacement of missing teeth with dental prostheses, whether fixed or removable, is often used to achieve an acceptable level of masticatory performance. Objective: The present study aimed to analyze the association between masticatory performance and age, gender, and oral health status based on the decayed, missing, and filled teeth (DMF-T) score, denture use, and denture condition in an adult population. Methods: This study included a total …
The Role Of Peer Influence On Oral Health Knowledge And Behaviors Among Adolescents, Maryam Sadeghipour Roudsari, Seyed Peyman Shariatpanahi, Mahshid Namdari, Mohammad Hossein Khoshnevisan, Mahsa Malek-Mohammadi, Mohammad Hadi Foroughmand
The Role Of Peer Influence On Oral Health Knowledge And Behaviors Among Adolescents, Maryam Sadeghipour Roudsari, Seyed Peyman Shariatpanahi, Mahshid Namdari, Mohammad Hossein Khoshnevisan, Mahsa Malek-Mohammadi, Mohammad Hadi Foroughmand
Journal of Dentistry Indonesia
Although many researchers, in different social sciences fields, are being attracted to the new potential promotional phenomenon, the influence of peer connections, the literature in dental public health is very poor. Objective: This article investigates the role of peer influence on individuals’ oral health knowledge and behavior among adolescents. Methods: The purpose of the study was to explore the correlation between secondary school students’ oral health u and knowledge within friendship groups. A valid and reliable questionnaire was developed. A total of 421 students (228 boys and 193 girls) aged between 12-13 years old participated in the study. …
An Indonesian Version Of Child Oral Health Impact Profile-Short Form 19 (Cohip-Sf19): Assessing Validity And Reliability, Siti L. Nuraini, Anton Rahardjo, Diah Ayu Maharani
An Indonesian Version Of Child Oral Health Impact Profile-Short Form 19 (Cohip-Sf19): Assessing Validity And Reliability, Siti L. Nuraini, Anton Rahardjo, Diah Ayu Maharani
Journal of Dentistry Indonesia
Previous surveys have indicated that the majority of Indonesian children have poor oral health. However, scant information is available on children’s oral health related quality of life (OHRQoL). The purpose of this study was to assess reliability as well as discriminant and convergent validity of Child Oral Health Impact Profile-Short Form 19 (COHIP-SF 19) Indonesian version. Methods: The Indonesian version of COHIP-SF 19 was developed according to the guidelines for the cross-cultural adaptation process. The instrument was tested among 529 children between 12 – 15 years old who were randomly selected from six junior high schools in Jakarta. The …
Prevalence And Risk Factors Of Drug-Induced Gingival Overgrowth In Hypertensive Patients, Haslina Taib, Muhammad Haziq Mohd Radzwan, Muhammad Annurdin Sabaruddin, Wan Majdiah Wan Mohamad, Noraini Mohamad
Prevalence And Risk Factors Of Drug-Induced Gingival Overgrowth In Hypertensive Patients, Haslina Taib, Muhammad Haziq Mohd Radzwan, Muhammad Annurdin Sabaruddin, Wan Majdiah Wan Mohamad, Noraini Mohamad
Journal of Dentistry Indonesia
Gingival overgrowth (GO) or enlargement is an unwanted effect occurring on the gingiva that commonly associated with medications. Hypertension is a global burden systemic conditions and showed high prevalent and more patients are taking antihypertensive drugs. Objective: This study aimed to assess the prevalence of drug-induced gingival overgrowth (DIGO) and its associated risk factors among hypertensive patients attending Hospital Universiti Sains Malaysia, Kelantan, Malaysia. Methods: A total of 42 patients with the mean age of 57.1 (SD=9.3) years had participated in this cross-sectional study. They were recruited if they had consumed anti-hypertensive agents for at least 6 months. Demographic …
Multiple Oral Ulcerations In A Seizure Patient With Undiagnosed Brain Arteriovenous Malformation, Ambar Kusuma Astuti, Febrina Rahmayanti
Multiple Oral Ulcerations In A Seizure Patient With Undiagnosed Brain Arteriovenous Malformation, Ambar Kusuma Astuti, Febrina Rahmayanti
Journal of Dentistry Indonesia
Multiple ulcerations are rarely caused by a traumatic event, but seizures can induce repeated injury to the oral mucosa. A patient with a seizure history possesses a challenge in their dental management. Objective: In order to describe a case of multiple oral ulceration in a post-seizure patient with undiagnosed arteriovenous malformation (AVM) in the left parietal lobe and provide short guidelines for dentists in managing patient with a seizure history. Case report: A 23-years old female had multiple oral ulceration in the right and left buccal mucosa and her tongue. She reported having a seizure attack six days before. …
A Case Of Ameloblastic Fibrodentinoma In The Posterior Maxilla, Akane Mochizuki, Rei Fukui, Toshihiko Amemiya, Yoshinori Arai, Masatake Asano
A Case Of Ameloblastic Fibrodentinoma In The Posterior Maxilla, Akane Mochizuki, Rei Fukui, Toshihiko Amemiya, Yoshinori Arai, Masatake Asano
Journal of Dentistry Indonesia
Ameloblastic fibrodentinoma (AFD) is a rare tumor with an incidence rate of less than 1%. When lesion with the histomorphology of ameloblastic fibroma(AF), which is true neoplasms, form dysplastic dentin, and had been referred to as AFD. It histologically consists of odontogenic ectomesenchyme resembling the dental papilla, epithelial strands, and nests resembling dental lamina and enamel organ with dentin formation. Although newly categorized as an odontoma by the WHO in 2017, this lesion was previously referred to as a rare odontogenic tumor by the WHO in 2005. Objective: We aim to summarize our case with other previous case reports …
Assessment Of Gingival Status And Gingival Overgrowth Among Immunosuppressed Patients In Universiti Sains Malaysia Hospital, Wan Majdiah Wan Mohamad, Syamimi Izzati Mat Zaid, Haslina Taib
Assessment Of Gingival Status And Gingival Overgrowth Among Immunosuppressed Patients In Universiti Sains Malaysia Hospital, Wan Majdiah Wan Mohamad, Syamimi Izzati Mat Zaid, Haslina Taib
Journal of Dentistry Indonesia
Drug-induced gingival overgrowth (DIGO) is defined as an abnormal growth of the gingiva due to adverse effect of some drugs such as immunosuppressant, calcium channel blocker, and anticonvulsant. Immunosuppressive drugs play an important role in controlling organ transplant rejection and were widely used to treat different diseases. Objective: Immunosuppressive drugs are used for prevention of transplant rejection and management of autoimmune disease. Drug-induced gingival overgrowth (GO) is abnormal growth of gingiva due to adverse effect of these drugs. This study aimed to assess the gingival status, the prevalence of gingival overgrowth and its associated factors among immunosuppressed patients. Methods …
Identification Of Adverse Drug Reactions In Congestive Heart Failure Patients In A Tertiary Care Hospital, West Nusa Tenggara, Indonesia, Dita Marina Lupitaningrum, Putri Ramdaniah, Depi Yuliana
Identification Of Adverse Drug Reactions In Congestive Heart Failure Patients In A Tertiary Care Hospital, West Nusa Tenggara, Indonesia, Dita Marina Lupitaningrum, Putri Ramdaniah, Depi Yuliana
Pharmaceutical Sciences and Research
Congestive Heart Failure (CHF) is a progressive health problem with high mortality and morbidity and has the potential to develop adverse drug reactions (ADRs). This study was conducted to determine the prevalence of potential ADRs, the types of drugs that cause ADRs, the types of ADRs, and the risk factors that affect the ADRs in CHF patients. Data were collected using medical record of hospitalized patient at the West Nusa Tenggara (NTB) Provincial Hospital, Indonesia, in 2017 to 2019. The assessment of the causality and severity of ADRs used the Naranjo algorithm and the Hartwig and Siegel scale. This study …
Comprehensive In Silico Analysis Of Christinin Molecular Behaviour From Ziziphus Spina-Christi Leaves On Propionibacterium Acnes, Fitrianti Darusman, Taufik Muhammad Fakih
Comprehensive In Silico Analysis Of Christinin Molecular Behaviour From Ziziphus Spina-Christi Leaves On Propionibacterium Acnes, Fitrianti Darusman, Taufik Muhammad Fakih
Pharmaceutical Sciences and Research
The role of in silico studies in the discovery of new drugs is very important and interesting in the recent years, where the results can be used as confirmation of the results of in vitro tests carried out experimentally in the laboratory. One of the herbal ingredients is Ziziphus spina-christi leaves with effective antibacterial activity, such as for acne-causing bacteria, namely Propionibacterium acnes. This is because it contains main secondary metabolites with saponins as the major components which contain christinin as its active compound. There are four known types of christinin, namely christinin-A, christinin-B, christinin-C, and christinin-D. In this …
A Review: Composition Of Neonatal Meconium Microbiota And Its Role For Potential Probiotic, Devi Oktaviyani, Raden Zulfa 'Alawiyyah, Putri Nusaiba, Amarila Malik
A Review: Composition Of Neonatal Meconium Microbiota And Its Role For Potential Probiotic, Devi Oktaviyani, Raden Zulfa 'Alawiyyah, Putri Nusaiba, Amarila Malik
Pharmaceutical Sciences and Research
Early-life period (≤ 1 month after birth) is critical for determining long- and short-term health of neonates. Composition of neonates’ gut microbiota varies greatly between individuals whose development is influenced by various factors including differences in maternal diet and lifestyle during pregnancy, related to population and ethnicity. Balanced microbial composition can create symbiosis among commensal microbes, immunomodulatory compound production, and subsequent immune response regulation. Unbalanced microbiota composition, characterized by more pathogenic organism, less diversity, and less resistance to disease, is called dysbiosis. Probiotic bacteria are a bacteria group contributing to the balance of neonates’ gut microbiota. Probiotic bacterial strains, such …
Interpersonal Relationship And Its Effect On Treatment Compliance In Patients With Type-2 Diabetes Mellitus, Fransiskus Samuel Renaldi, Woro Riyadina, Muhammad Qamar, Rani Sauriasari
Interpersonal Relationship And Its Effect On Treatment Compliance In Patients With Type-2 Diabetes Mellitus, Fransiskus Samuel Renaldi, Woro Riyadina, Muhammad Qamar, Rani Sauriasari
Pharmaceutical Sciences and Research
Type-2 diabetes mellitus has become a chronic disease that can lead to serious complications and can only be prevented by compliant treatment of the patients. Compliance can be influenced by various factors, one of which is interpersonal factors. This study aimed to identify various interpersonal relationship problems between patients and healthcare workers that can affect their treatment compliance behavior. This study employed a qualitative design with phenomenological methods. This research was conducted in Central Bogor City in March-August 2020. The data were collected by conducting in-depth interviews with 20 type-2 diabetes mellitus patients who had been confirmed by the Community …
Drug Repurposing And Dosage Form Development Of Anti-Covid-19, Kevin Kwok
Drug Repurposing And Dosage Form Development Of Anti-Covid-19, Kevin Kwok
Pharmaceutical Sciences and Research
The COVID-19 pandemic has been occurring approximately for more than 1 year. This pandemic has been a health issue that hits all countries in the world caused by the transmission of SARS-CoV-2 virus from one individual to another. The symptoms showed from the infected are fever, shortness of breath, dry cough, headache, and sore throat, among others. The SARS-CoV-2 virus is transmitted through sneezing, coughing, talking, and touching infected objects. Along with this transmission, the SARS-CoV-2 virus will continue to mutate. This mutation becomes an obstacle as well as a challenge to find drugs that can overcome the SARS-CoV-2 virus …
Preliminary Characterization, Antioxidant And Antiproliferative Properties Of Polysaccharide From Caulerpa Taxifolia, Ariane Marie Bayro, Joanne Katherine Manlusoc, Renaliza Alonte, Catherine Caniel, Patrick Conde, Carlo Embralino
Preliminary Characterization, Antioxidant And Antiproliferative Properties Of Polysaccharide From Caulerpa Taxifolia, Ariane Marie Bayro, Joanne Katherine Manlusoc, Renaliza Alonte, Catherine Caniel, Patrick Conde, Carlo Embralino
Pharmaceutical Sciences and Research
Macroalgae are abundant sources of bioactive polysaccharides and prospective candidates for effective and non-toxic substances. This study aims to preliminary characterize and determine the in vitro antioxidant activity and cancer cell growth inhibitory activity against human lung adenocarcinoma cell (A549) of the polysaccharide from an invasive green alga, Caulerpa taxifolia. Crude polysaccharide (CP) was extracted from the dried algal sample of C. taxifolia by hot water extraction followed by absolute ethanol precipitation. CP was subjected to preliminary chemical characterization, including protein, carbohydrate, and sulfate content analysis by Kjeldahl titrimetry, acid hydrolysis, gravimetry, and ashing-acid water digestion ion chromatography, respectively. …
Puasa Ramadan Dan Diabetes Melitus: Risiko, Manfaat Dan Peluang Penelitian, Dicky L Tahapary, Syahidatul Wafa, Dante S. Harbuwono
Puasa Ramadan Dan Diabetes Melitus: Risiko, Manfaat Dan Peluang Penelitian, Dicky L Tahapary, Syahidatul Wafa, Dante S. Harbuwono
Jurnal Penyakit Dalam Indonesia
No abstract provided.
Cloning Of Pe11 (Lipx, Rv1169c) Gene Of Mycobacterium Tuberculosis Beijing Strain To Pcdna3.1 Plasmid Vector, Lulut Azmi Supardi, Andriansjah Rukmana, Fithriyah Sjatha
Cloning Of Pe11 (Lipx, Rv1169c) Gene Of Mycobacterium Tuberculosis Beijing Strain To Pcdna3.1 Plasmid Vector, Lulut Azmi Supardi, Andriansjah Rukmana, Fithriyah Sjatha
Makara Journal of Science
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. It is a persistent global health problem with a high mortality rate. Currently, TB is controlled by administering the Bacillus Calmette-Guerin (BCG) vaccine, but the effectiveness of its protection varies among individuals in a population. The pe/ppe gene family comprises a typical group of genes that play a role in avoiding the host immune response and inducing persistent TB infection. Based on in silico analysis, the pe11 gene has estimated immunogenicity and potential as a TB seed vaccine candidate. The pe11 gene from an Indonesian isolate of an M. …
The Pattern Of Microorganism On Adult Acute Leukemia Patientsduring Bacterial Surveillance And Febrile Neutropenia At Ciptomangunkusumo Hospital, Lugyanti Sukrisman
The Pattern Of Microorganism On Adult Acute Leukemia Patientsduring Bacterial Surveillance And Febrile Neutropenia At Ciptomangunkusumo Hospital, Lugyanti Sukrisman
Jurnal Penyakit Dalam Indonesia
Introduction. The standard intensive chemotherapy in acute leukemia patients will cause severe neutropenia and infection (febrile neutropenia) with high fatality rate. The availability of accurate data on causative pathogens is essential to the appropriate selection of empirical therapy and usually obtained from bacterial surveillance. This study was intended to evaluate bacterial pathogens found on surveillance and during febrile neutropenia in acute leukemia patients undergoing chemotherapy at Cipto Mangunkusumo Hospital and to provide information for antimicrobial policy in the hospital. Methods. A retrospective study from data of bacterial surveillance of acute leukemia patients undergoing chemotherapy during 2008-2010 in isolation room for …
Management Of Diabetic Ketoacidosis In Patient With Heartfailure, Dicky Febrianto, Est Hindariati
Management Of Diabetic Ketoacidosis In Patient With Heartfailure, Dicky Febrianto, Est Hindariati
Jurnal Penyakit Dalam Indonesia
Diabetic ketoacidosis (DKA) is diabetes mellitus emergency which is defined by the biochemical triad of hyperglycemia, ketonemia, and acidemia. Diabetic ketoacidosis continues to have high rates of morbidity and mortality despite advances in the treatment of diabetes. Crucial aspects of DKA management involve adequate replacement of fluids and electrolytes, particularly potassium, and the continuous administration of insulin. Hydration status in patients with DKA and heart failure can be assessed by physical examination, such as consciousness, vital signs, capillary refill time, skin turgor, jugular venous pressure, and signs of pulmonary edema. Invasive and non-invasive methods can also assess fluid adequacy in …
Correlation Of Ramadan Fasting With Hba1c And Lipid Profilelevel Changes In The Risk Stratification Of Complications Indiabetes Mellitus Patients, Rinadhi Reza Bramantya, Putu Moda Arsana, Laksmi Sasiarini
Correlation Of Ramadan Fasting With Hba1c And Lipid Profilelevel Changes In The Risk Stratification Of Complications Indiabetes Mellitus Patients, Rinadhi Reza Bramantya, Putu Moda Arsana, Laksmi Sasiarini
Jurnal Penyakit Dalam Indonesia
Introduction. Diabetic patients will still do Ramadan fasting, which could affect the levels of HbA1C and lipid change after Ramadan. This study aimed to identify the correlation between fasting of Ramadan risk stratification with HbA1C and lipid levels diabetic patients who run the fast of Ramadan. Methods. This was a survey research using pre - post test. Study was conducted among diabetes patients who meet the criteria: carry out routine controls before and after Ramadan fasting at dr. Saiful Anwar Malang Hospital, filling in the required data, and underwent examination laboratory. Patients were grouped into moderate, high, and very high-risk …
Correlation Between Parathyroid Hormone Serum Levels Andabdominal Aortic Calcification In Chronic Hemodialysis Patientsat Dr. Mohammad Hoesin Center General Hospital Palembang, M Yusuf Arief Akbar, Zulkhair Ali, Taufik Indrajaya, Novadian Suhaimi, Sna Ratnasari Devi, Erial Bahar
Correlation Between Parathyroid Hormone Serum Levels Andabdominal Aortic Calcification In Chronic Hemodialysis Patientsat Dr. Mohammad Hoesin Center General Hospital Palembang, M Yusuf Arief Akbar, Zulkhair Ali, Taufik Indrajaya, Novadian Suhaimi, Sna Ratnasari Devi, Erial Bahar
Jurnal Penyakit Dalam Indonesia
Introduction. Cardiovascular disease is the most common cause of death in patients with chronic kidney disease (CKD). This is evidenced by the finding of vascular calcification in CKD patients. The process of vascular calcification that occurs is often associated with secondary hyperparathyroid conditions that are complications of CKD patients. The aim of this study was to asses the relationship between serum PTH levels and the abdominal aorta calcification (AAC) in CKD patients undergoing hemodialysis (HD) Methods. This observational analytic study with cross-sectional correlation test was conducted in the internal medicine ward of dr. Mohammad Hoesin Palembang from July to December …
Correlation Of Haemoglobin Platelet Ratio (Hpr) And Leukocyteplatelet Ratio (Lpr) With Syntax-2 Score In Stemi Patients, Muhammad Ikhsan, Sally Aman Nasution, Andhika Rachman, Muhadi Muhadi
Correlation Of Haemoglobin Platelet Ratio (Hpr) And Leukocyteplatelet Ratio (Lpr) With Syntax-2 Score In Stemi Patients, Muhammad Ikhsan, Sally Aman Nasution, Andhika Rachman, Muhadi Muhadi
Jurnal Penyakit Dalam Indonesia
Introduction. Various studies have concluded the association between various markers of inflammation with the clinical outcome in STEMI patients. However, most of these markers are quite expensive and not available in healthcare facilities. Hence, we aim to study the correlation between haemoglobin platelet ratio (HPR) and leucocyte platelet ratio (RPL) and the clinical outcomes of STEMI patients. Methods. This is a cross-sectional study performed in adult patients with STEMI who were hospitalized in Intensive Coronary Care Unit Cipto Mangunkusumo Hospital between January 2016 and October 2020. The data was analyzed by testing the correlation between HPR and LPR with SYNTAX-2 …
Egfr Mutation As A Predictive Factor To Treatment Response Oftki (Tyrosine Kinase Inhibitor) In Non-Small Cell Lung Cancerstage 4: A Case Report, Wulyo Rajabto, Yohana Kusuma Angkasa
Egfr Mutation As A Predictive Factor To Treatment Response Oftki (Tyrosine Kinase Inhibitor) In Non-Small Cell Lung Cancerstage 4: A Case Report, Wulyo Rajabto, Yohana Kusuma Angkasa
Jurnal Penyakit Dalam Indonesia
Non-small cell lung cancer (NSCLC) typically presents in patients at an advanced stage, with a poor prognosis. The development of epidermal growth factor receptor (EGFR) – tyrosine kinase inhibitors (TKIs) and the systematic identification of EGFR mutations heralded the advent of targeted therapy in lung cancer, transforming the landscape of its treatment and prognosis. This is a case of 37 years-old female patient presented with metastatic bone disease secondary to pulmonary adenocarcinoma EGFR mutation positive which demonstrated a remarkable result to TKI.
Comparative Evaluation Of Alpha-Fetoprotein Serum Inhepatocellular Carcinoma Patients With Non-Viral Etiology, Gita Aprilicia, Krisnawati Bantas, Syahrizal Syarif, Kemal Fariz Kalista
Comparative Evaluation Of Alpha-Fetoprotein Serum Inhepatocellular Carcinoma Patients With Non-Viral Etiology, Gita Aprilicia, Krisnawati Bantas, Syahrizal Syarif, Kemal Fariz Kalista
Jurnal Penyakit Dalam Indonesia
Introduction. Non-viral etiology of hepatocellular carcinoma (HCC) now needs attention. Hepatocellular carcinoma which was caused by hepatitis B and hepatitis C could be controlled in the national program, while HCC from non-B non-C etiology has become a further concern with the with the increased of metabolic syndrome. Serum alpha-fetoprotein is a tumor marker commonly used for screening for HCC in patients with liver cirrhosis (LC). However, in HCC patients with nonviral etiology, AFP serum tends to be normal. This study aimed to evaluate the performance of AFP serum based in HCC and LC patient with non-viral etiology and to evaluate …
Retraction: Correlation Of Serum Uric Acid Levels With The Severity Of Coronary Artery Stenosis In Patients With Acute Coronarysyndrome: Meta-Analysis Study, Diding Heri Prasetyo, Sally Aman Nasution, Idrus Alwi, Murdani Abdullah
Retraction: Correlation Of Serum Uric Acid Levels With The Severity Of Coronary Artery Stenosis In Patients With Acute Coronarysyndrome: Meta-Analysis Study, Diding Heri Prasetyo, Sally Aman Nasution, Idrus Alwi, Murdani Abdullah
Jurnal Penyakit Dalam Indonesia
Introduction. The relationship between serum uric acid (SUA) level and ischemic heart disease abides controversial and still has not been established as a cardiovascular risk factor. The cooperative interaction between those two factors is not fully understood. Prior epidemiological evidences of the causal relationship is still argumentative. There were various studies using the same methods yet the outcome were different. This study aims to conduct a meta-analysis to synthesize the results of recent studies in order to obtain data quantitatively and also accurately. Methods. This study protocol was registered with PROSPERO (CRD42020210948), and conducted according to PRISMA guidelines, tracing studies …
Biological Activity And Solubility Of 5-Methoxy-1,4-Benzoquinone Having Bromoheptyl And Bromodecyl Substituents In The N-Octanol/Water System, Siti Mariyah Ulfa, Fath Dwisari, Laras Pangesti, Mohammad Farid Rahman
Biological Activity And Solubility Of 5-Methoxy-1,4-Benzoquinone Having Bromoheptyl And Bromodecyl Substituents In The N-Octanol/Water System, Siti Mariyah Ulfa, Fath Dwisari, Laras Pangesti, Mohammad Farid Rahman
Makara Journal of Science
The biological activity and solubility of compounds are influenced by its chemical structure. These properties can be improved by substituting alkyl, alkoxy, and/or haloalkane in the parent skeleton. In this research, the synthesis of 3-(7-bromoheptyl)-2-methyl-5-methoxy-1,4-benzoquinone (3a) and 3-(10-bromodecyl)-2-methyl-5-methoxy-1,4-benzoquinone (3b) was achieved through the decarboxylation reaction. The solubility and biological activity of 3a and 3b were compared with that of thymoquinone (TQ), which acts as an anti-inflammatory agent. Compounds 3a and 3b were successfully synthesized and analyzed using Fourier Transform Infra-Red (FTIR) and Nuclear Magnetic Resonance (NMR). The FTIR spectrum showed the increasing intensity of …
Synthesis Of 1-(4-Ethoxy-3-Methoxybenzyl)-1,10-Phenanthrolin-1-Ium Bromide And Its Evaluation As Antiplasmodium Through Heme Polymerization Inhibitory Activity (Hpia) Assay, Dhina Fitriastuti, Viny Alfiyah, Mustofa Mustofa, Jumina Jumina, Muhammad Idham Darussalam Mardjan
Synthesis Of 1-(4-Ethoxy-3-Methoxybenzyl)-1,10-Phenanthrolin-1-Ium Bromide And Its Evaluation As Antiplasmodium Through Heme Polymerization Inhibitory Activity (Hpia) Assay, Dhina Fitriastuti, Viny Alfiyah, Mustofa Mustofa, Jumina Jumina, Muhammad Idham Darussalam Mardjan
Makara Journal of Science
This study describes the development of N-benzyl-1,10-phenantrolinium salt as an antiplasmodium agent. The salt, that is, 1-(4-ethoxy-3-methoxybenzyl)-1,10-phenanthrolin-1-ium bromide, was prepared using vanillin as the starting material in four simple synthetic steps. First, the alkylation of vanillin using diethyl sulfate produced 4-ethoxy-3-methoxybenzaldehyde in 79% yield. Second, the reduction of the protected vanillin by NaBH4 through the grinding method allowed us to obtain 4-ethoxy-3-methoxybenzyl alcohol in 96% yield. Next, the bromination of the benzyl alcohol under solvent-free condition led to the formation of the corresponding benzyl bromide, which in turn underwent bimolecular nucleophilic substitution with 1,10-phenanthroline to produce the desired …
Analysis Of Measles Vaccination Refusal On Social Media (Facebook) Among Anti-Vaccine Communities In Indonesia, Dwi Meilani, Evi Martha, Hadi Pratomo, Indah Jamiatun Hasanah, Somporn Rungreangkulkij
Analysis Of Measles Vaccination Refusal On Social Media (Facebook) Among Anti-Vaccine Communities In Indonesia, Dwi Meilani, Evi Martha, Hadi Pratomo, Indah Jamiatun Hasanah, Somporn Rungreangkulkij
Kesmas
Measles is one of the main causes of global mortality in the under-fives. The existence of groups that reject immunization caused a decrease in immunization coverage. Anti-vaccine messages are widely delivered on social media. Identification of vaccine rejection behavior can be used as the basis to formulate effective program strategies. The design of this study used rapid assessment procedures (RAP). The informants were from two anti-vaccine communities in the Facebook group. In-depth interviews and observations were done for data collection, and data analysis was performed using the Framework Method. The results found that determinants, such as knowledge, beliefs in health …
Exclusive Breastfeeding History Risk Factor Associated With Stunting Of Children Aged 12–23 Months, Nurhalina Sari, Marlida Yuliza Manjorang, Zakiyah Zakiyah, Madeleine Randell
Exclusive Breastfeeding History Risk Factor Associated With Stunting Of Children Aged 12–23 Months, Nurhalina Sari, Marlida Yuliza Manjorang, Zakiyah Zakiyah, Madeleine Randell
Kesmas
Stunting (low height-for-age) remains a global and national health problem because it increases the risk of disturbances in growth and development and mortality. Banjar Margo District, Tulang Bawang Regency, has the second-highest prevalence in Lampung Province, Indonesia. This study aimed to analyze the association of exclusive breastfeeding history and stunting in children aged 12–23 months in Banjar Margo District. This study used a cross-sectional design on 193 children aged 12–23 months. It was primary data conducted between April and May 2018 with a questionnaire. Data analysis was performed using the chi-square test and multiple logistic regression. The result showed that …
Junk Food Consumption And Symptoms Of Mental Health Problems: A Meta-Analysis For Public Health Awareness, Muhammad Hafizurrachman, Risky Kusuma Hartono
Junk Food Consumption And Symptoms Of Mental Health Problems: A Meta-Analysis For Public Health Awareness, Muhammad Hafizurrachman, Risky Kusuma Hartono
Kesmas
Junk food consumption increases the risk of having symptoms of mental health problems. This study aimed to conduct a meta-analysis to assess the association between junk food and symptoms of mental health problems. Six researchers, two primary researchers, and four assistant researchers, from October to December 2020 conducted a systematic literature review. The data sources were selected from Pubmed and Science Direct articles published from 2010 to 2020. Those websites were check-marked for text availability for original articles, using keywords for junk foods and mental health. This study had inclusion criteria for selecting and organizing articles using the Preferred Reporting …
Determinants Of Exclusive Breastfeeding Practices Of Female Healthcare Workers In Jakarta, Indonesia, Siti Rapingah, Nova Muhani, Besral Besral, Poppy Yuniar
Determinants Of Exclusive Breastfeeding Practices Of Female Healthcare Workers In Jakarta, Indonesia, Siti Rapingah, Nova Muhani, Besral Besral, Poppy Yuniar
Kesmas
The World Health Organization (WHO) recommended that mothers worldwide exclusively breastfeed their infants for the child's first six months to achieve optimal growth, development, and health. Indonesia had not fulfilled the global standard of breastfeeding rate so that there was low coverage of exclusive breastfeeding in East Jakarta, especially for female healthcare workers. This study aimed to determine the factors associated with exclusive breastfeeding practices of healthcare workers. This was a quantitative study using a cross-sectional design. The recruited sample consisted of 85 female public health center workers with infants aged 6-24 months. Data were collected using self-administered questionnaires. Logistic …
Risk Perception For Developing Erectile Dysfunction Among Malaysian Men With Type 2 Diabetes Mellitus, Anuar Mohamad, Hizlinda Tohid, Saharuddin Ahmad, Seng Fah Tong, Mahadir Ahmad
Risk Perception For Developing Erectile Dysfunction Among Malaysian Men With Type 2 Diabetes Mellitus, Anuar Mohamad, Hizlinda Tohid, Saharuddin Ahmad, Seng Fah Tong, Mahadir Ahmad
Kesmas
Risk perception for developing erectile dysfunction (ED) is an appreciation of the susceptibility to having ED and its severity. This study examined this risk perception and its associated factors among 180 men with type 2 diabetes mellitus (T2DM), who claimed not to have ED. This cross sectional study was conducted at a public health clinic using a validated self-administered questionnaire, which assessed participant characteristics, perceived susceptibility to developing ED, perceived severity of ED, and knowledge on risk factors for ED. About 71.1% had an inaccurate perception of susceptibility to developing ED and their perception on its severity was moderate (median …