Medicine and Health Sciences Commons^™

Controlling Dentistry-Related Musculoskeletal Disorders With Ergonomic Interventions In Lahore, Pakistan, Marriyam Nasar, Farwa Rubab, Hazik Bin Shahzad, Minam Qureshi, Maham Shahid, Pakiza Batool

Makara Journal of Health Research

Background: Musculoskeletal disorders (MSDs) usually result from a prolonged static position and repetitive movements. A comfortable environment, appropriate working position, and multiple short breaks could alleviate MSDs. While the occasional back or neck ache is not a cause for alarm, regularly occurring pain or discomfort, if ignored, may further develop into an injury or career-ending disability.

Methods: A total of 370 dentists were selected from two dental hospitals and multiple dental clinics in Lahore, Pakistan. Current MSDs were recorded with the Standardized Nordic Questionnaire (SNQ). Information sheets containing dental ergonomics and back and tendon-gliding exercises were distributed among …

Prevalence And Impacts Of Musculoskeletal Pain Among The Elderly Living In The East Coast Region Of Peninsular Malaysia, Muhammad Kamil Che Hasan, Nur Nabila Izzati Asmera, Suliza Sulaiman, Mohd Said Nurumal, Nik Noor Kaussar Nik Mohd Hatta

Makara Journal of Health Research

Background: Musculoskeletal pain commonly affects the elderly, but the extent of this problem within the Malaysian community remains unknown. This study aimed to investigate the prevalence and impact of musculoskeletal pain among the elderly living in the community.

Methods: Elderly individuals aged 60 years and above with musculoskeletal pain and intact cognition were recruited for this study. Musculoskeletal pain was scored using the Nordic Musculoskeletal Questionnaire, and functional ability was assessed via the Lawton Instrumental Activities of Daily Living scale. Mental wellbeing was evaluated using the Short Warwick–Edinburgh Mental Wellbeing scale, and risk of falling was determined via …

Factors Affecting Health-Promoting Lifestyles Among Community Residents At East Gyogone Ward, Insein Township, Rita Meemee, Naw Ohn Khin Khin, Min Htike Aung

Makara Journal of Health Research

Background: Non-communicable diseases (NCDs) are becoming major challenges for health professionals. Health-promoting lifestyles (HPL) are one of the main criteria for determining health and recognized as the main factor affecting the development of chronic NCDs. This study aimed to determine factors affecting HPL practices among community residents.

Methods: A cross-sectional descriptive study was conducted in Insein Township, Yangon, Myanmar. A total of 194 participants were recruited by using systematic sampling method, and self-administered questionnaires for sociodemographic characteristics and Health-Promoting Lifestyle Profile II were used for data collection. Independent sample t-test and one-way analysis of variance were employed …

Determinants Of Postnatal Care Service Utilization In Indonesia: A Secondary Analysis Using The Indonesian Health And Demographics Survey, Haerawati Idris, Willyana Syafriyanti

Makara Journal of Health Research

Background: The postnatal complication that occurs in the first week after childbirth is one of the causes of maternal death in Indonesia. However, it can be prevented with postnatal care (PNC). This study aims to analyze the determinants of PNC service utilization in Indonesia.

Methods: This quantitative study employed a cross-sectional study design and used secondary data from the Indonesian Health and Demographics Survey of 2017. The sample consisted of 14,724 women aged 15–49 years. We assessed the predictors of PNC service utilization using multivariate logistic regression models.

Results: About 78.4% of the respondents utilized PNC services. …

A Cross-Sectional Study On Bullying And Psychological Disturbances Among Malaysian School Children, Muhammad Lokman Md Isa, Nurfatin Aina Mocktar, Wisam Nabeel Ibrahim, Mohd Said Nurumal, Muhammad Kamil Che Hasan

Makara Journal of Health Research

Background: Bullying is a common violence in school and has become a major public health and global concern. Bullying influences mental health and is identified as a leading factor of depression. Therefore, this study aimed to identify bullying prevalence and its association toward psychological disturbances (stress, anxiety, and depression).

Methods: This cross-sectional study was conducted in three secondary schools in Kuantan. After obtaining consent from parents/guardians, participants were asked to answer a self-administered questionnaire, including School Climate Bullying Survey, Depression Anxiety Stress Questionnaire-21, Patient Depression Questionnaire, and Generalized Anxiety Disorder. Demographic data were self-reported. Data were analyzed using …

Soft Drink Consumption Patterns Of Middle School Students In North Okkalarpa, Moh Moh Thwe, Sein Yaw May, Min Htike Aung

Makara Journal of Health Research

Background: Urbanization and economic development in Myanmar have brought about culture and dietary transition from a traditional to a westernized diet. The health of the nation, especially the youth, may influence the changing dietary patterns: i.e., the higher the soft drink consumption, the higher the prevalence of soft drink-related diseases.

Methods: This cross-sectional study was carried out among 250 middle school students in North Okkalarpa Township, Yangon Region. Data were collected using self-structured questionnaires, and respondents were selected by using simple random sampling method.

Results: In this study, 81.2% of the students consumed soft drink once a …

Mothers’ Nutritional Knowledge, Self-Efficacy, And Practice Of Meal Preparation For School-Age Children In Yangon, Myanmar, Wut Yee Phyo, Ohn Khin Khin, Min Htike Aung

Makara Journal of Health Research

Background: Childhood malnutrition is a global public health concern. For Myanmar, mothers play a prominent role in improving the nutritional status of children as they prepare meals for children.

Methods: This community-based cross-sectional analytical study was conducted on 367 mother-child pairs (6–10 years). Significantly, systematic random sampling and structured questionnaires were utilized in this study.

Results: The mean age of mothers was 35.73 ± 6.9 years, and a majority had fair nutritional knowledge (52.3%), good self-efficacy (79.8%), and good practice of meal preparation (59.4%). The prevalence of childhood malnutrition was categorized as stunting (18.2%), underweight (18.8%), wasting …

Effects Of Flaxseed (Linum Usitatissimum) Extract On The Osteoblast Differentiation Potential Of Stem Cells Derived From Human Exfoliated Deciduous Teeth, Nur Sazwi Nordin, Khairani Idah Mokhtar, Basma Ezzat Mustafa, Widya Lestari, Solachuddin Ja Ichwan Jauhari Ichwan Ichwan, Deny Susanti Darnis, Thirumulu Ponnuraj Kannan, Azlina Ahmad

Makara Journal of Health Research

Background: Flaxseed promotes bone health and possibly induces bone regeneration. However, the capacity of flaxseed to induce the differentiation of stem cells into osteoblasts remains unreported. Accordingly, this study aimed to determine the effects of flaxseed extract on the osteoblast differentiation potential of stem cells derived from human exfoliated deciduous teeth (SHED).

Methods: SHED cultured in osteoblast induction media (OIM) were treated with 4 mg/mL flaxseed extract. RNA was collected and extracted with Total RNA Mini Kit (Geneaid) from cells cultured at days 1, 3, 7, 14, and 21 and subjected to reverse-transcriptase PCR for osteoblast markers ( …

Effects Of Ectodermal Dysplasia On The Maxilla: A Study Of Cone-Beam Computed Tomography, Beyza Karadede Ünal

Makara Journal of Health Research

Background: This study aimed to examine the effects of ectodermal dysplasia (ED) on the transverse width of the maxillary bone.

Methods: The ED group was composed of seven people, while the control group consisted of retrospective cone-beam computed tomography images of seven individuals with skeletal class 1 relationship. Images on the sagittal planes were taken, and cross-sections were taken from the longest point of the Anterior Nasal Spine-Posterior Nasal Spine line. The distance between the distal anterior canine teeth from the right buccal cortical bone to the left buccal cortical bone was measured. At the posterior region, the …

Prevalence And Associated Factors Of Urinary Incontinence Among Elderly In Pekanbaru, Indonesia, Wulan Sari

Makara Journal of Health Research

Background: The proportion of the elderly in Riau Province was 4.8% higher than that (4.2%) in 2011. Urinary incontinence (UI) is a common health problem among the elderly. This study aims to determine the prevalence and associated factors for UI among the elderly (≥60 years).

Methods: This cross-sectional study was conducted in 20 public health centers in Pekanbaru City in 2018. A total of 351 elderly meeting the inclusion criteria were enrolled. Gender, age, education, occupation, marital status, obesity, depression, cognitive impairment, smoking status, history of chronic cough, and history of lower abdominal surgery served as the independent …

Effect Of Passive Tobacco Smoking Exposure On The Periodontal Status Of Turkish Children, Raif Alan, Onur Gezgi̇n, Emre Korkut, Şükriye Türkoğlu, Esra Çeli̇k, Seyfullah Hali̇loğlu

Journal of Dentistry Indonesia

Objective: This study aimed to assess the effect of passive tobacco smoking (PTS) through the comparison of the periodontal status and the C-reactive protein (CRP) and cotinine levels in the biologic fluids in children who are exposed and unexposed to PTS. Methods: A total of 148 participants, whom had smokers (PTS-exposed, n=82) and non-smokers (PTS-unexposed, n=66) in their families, respectively, were included in the study. Gingival index, plaque index, probing depth, and bleeding on probing were recorded. Moreover, saliva, urine, and gingival crevicular fluid samples were collected. CRP and cotinine levels in the biological fluids were determined by …

Periodontal Parameters And Anti-Cardiolipin Antibodies Following Periodontal Therapy In Chronic Periodontitis, Wan Majdiah Wan Mohamad, Noor Rashidah Saad, Siti Lailatul Akmar Zainuddin, Haslina Taib

Journal of Dentistry Indonesia

Anti-cardiolipin (anti-CL) antibodies are autoantibodies which are directed against cell membrane phospholipids. A significant number of periodontitis patients showed positive for anti-CL antibody. Objective: This study aimed to determine the periodontal parameters and anti-CL antibodies levels before and after non-surgical periodontal therapy in chronic periodontitis. Methods: This cross-sectional study had been carried out at Periodontal Clinic, Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. Thirty five chronic periodontitis (CP) and 39 non-periodontitis (NP) patients underwent clinical periodontal examination at baseline. Plaque index (PI), gingival index (GI), periodontal pocket depth (PPD), and clinical attachment loss (CAL) were measured. Scaling …

Associations Of Electromyographic Activity Of Anterior Temporalis Muscles, Sex, And Occlusal Classes In Asymptomatic Young Adults, Aneta Wieczorek, Marcin Czarnek, Jolanta E. Loster

Journal of Dentistry Indonesia

Symmetry evaluation of the craniofacial complex generally involves models of mandibular movement and masticatory muscle activity, especially during the growth of the craniofacial complex. Objectives: The aim of the study was to determine what, if any, associations exist between the activity of the masticatory muscles, sex, and occlusal classes in asymptomatic young adults. Methods:18-year-old volunteers, showing no symptoms of TMD based on an RDC/TMD examination, were included in the study.Surface electromyography (sEMG) recording was used to quantify the activity of masticatory muscles. The occlusal contact points were analyzed using a T-scan III Evolution 7.01 device. Occlusal classes were …

The Association Between Masticatory Performance, Oral Health Status, And Dental Prostheses In Adults At A Dental Hospital In Jakarta, Fakhrana Ariani Ayub, Farisza Gita, Nina Ariani

Journal of Dentistry Indonesia

Masticatory performance has been studied extensively in the past few decades. Age, gender, the number of teeth in occlusion, occlusal contact area, salivary flow, and neurophysiological deficits influence the masticatory process. The replacement of missing teeth with dental prostheses, whether fixed or removable, is often used to achieve an acceptable level of masticatory performance. Objective: The present study aimed to analyze the association between masticatory performance and age, gender, and oral health status based on the decayed, missing, and filled teeth (DMF-T) score, denture use, and denture condition in an adult population. Methods: This study included a total …

The Role Of Peer Influence On Oral Health Knowledge And Behaviors Among Adolescents, Maryam Sadeghipour Roudsari, Seyed Peyman Shariatpanahi, Mahshid Namdari, Mohammad Hossein Khoshnevisan, Mahsa Malek-Mohammadi, Mohammad Hadi Foroughmand

Journal of Dentistry Indonesia

Although many researchers, in different social sciences fields, are being attracted to the new potential promotional phenomenon, the influence of peer connections, the literature in dental public health is very poor. Objective: This article investigates the role of peer influence on individuals’ oral health knowledge and behavior among adolescents. Methods: The purpose of the study was to explore the correlation between secondary school students’ oral health u and knowledge within friendship groups. A valid and reliable questionnaire was developed. A total of 421 students (228 boys and 193 girls) aged between 12-13 years old participated in the study. …

An Indonesian Version Of Child Oral Health Impact Profile-Short Form 19 (Cohip-Sf19): Assessing Validity And Reliability, Siti L. Nuraini, Anton Rahardjo, Diah Ayu Maharani

Journal of Dentistry Indonesia

Previous surveys have indicated that the majority of Indonesian children have poor oral health. However, scant information is available on children’s oral health related quality of life (OHRQoL). The purpose of this study was to assess reliability as well as discriminant and convergent validity of Child Oral Health Impact Profile-Short Form 19 (COHIP-SF 19) Indonesian version. Methods: The Indonesian version of COHIP-SF 19 was developed according to the guidelines for the cross-cultural adaptation process. The instrument was tested among 529 children between 12 – 15 years old who were randomly selected from six junior high schools in Jakarta. The …

Prevalence And Risk Factors Of Drug-Induced Gingival Overgrowth In Hypertensive Patients, Haslina Taib, Muhammad Haziq Mohd Radzwan, Muhammad Annurdin Sabaruddin, Wan Majdiah Wan Mohamad, Noraini Mohamad

Journal of Dentistry Indonesia

Gingival overgrowth (GO) or enlargement is an unwanted effect occurring on the gingiva that commonly associated with medications. Hypertension is a global burden systemic conditions and showed high prevalent and more patients are taking antihypertensive drugs. Objective: This study aimed to assess the prevalence of drug-induced gingival overgrowth (DIGO) and its associated risk factors among hypertensive patients attending Hospital Universiti Sains Malaysia, Kelantan, Malaysia. Methods: A total of 42 patients with the mean age of 57.1 (SD=9.3) years had participated in this cross-sectional study. They were recruited if they had consumed anti-hypertensive agents for at least 6 months. Demographic …

Multiple Oral Ulcerations In A Seizure Patient With Undiagnosed Brain Arteriovenous Malformation, Ambar Kusuma Astuti, Febrina Rahmayanti

Journal of Dentistry Indonesia

Multiple ulcerations are rarely caused by a traumatic event, but seizures can induce repeated injury to the oral mucosa. A patient with a seizure history possesses a challenge in their dental management. Objective: In order to describe a case of multiple oral ulceration in a post-seizure patient with undiagnosed arteriovenous malformation (AVM) in the left parietal lobe and provide short guidelines for dentists in managing patient with a seizure history. Case report: A 23-years old female had multiple oral ulceration in the right and left buccal mucosa and her tongue. She reported having a seizure attack six days before. …

A Case Of Ameloblastic Fibrodentinoma In The Posterior Maxilla, Akane Mochizuki, Rei Fukui, Toshihiko Amemiya, Yoshinori Arai, Masatake Asano

Journal of Dentistry Indonesia

Ameloblastic fibrodentinoma (AFD) is a rare tumor with an incidence rate of less than 1%. When lesion with the histomorphology of ameloblastic fibroma(AF), which is true neoplasms, form dysplastic dentin, and had been referred to as AFD. It histologically consists of odontogenic ectomesenchyme resembling the dental papilla, epithelial strands, and nests resembling dental lamina and enamel organ with dentin formation. Although newly categorized as an odontoma by the WHO in 2017, this lesion was previously referred to as a rare odontogenic tumor by the WHO in 2005. Objective: We aim to summarize our case with other previous case reports …

Assessment Of Gingival Status And Gingival Overgrowth Among Immunosuppressed Patients In Universiti Sains Malaysia Hospital, Wan Majdiah Wan Mohamad, Syamimi Izzati Mat Zaid, Haslina Taib

Journal of Dentistry Indonesia

Drug-induced gingival overgrowth (DIGO) is defined as an abnormal growth of the gingiva due to adverse effect of some drugs such as immunosuppressant, calcium channel blocker, and anticonvulsant. Immunosuppressive drugs play an important role in controlling organ transplant rejection and were widely used to treat different diseases. Objective: Immunosuppressive drugs are used for prevention of transplant rejection and management of autoimmune disease. Drug-induced gingival overgrowth (GO) is abnormal growth of gingiva due to adverse effect of these drugs. This study aimed to assess the gingival status, the prevalence of gingival overgrowth and its associated factors among immunosuppressed patients. Methods …

Identification Of Adverse Drug Reactions In Congestive Heart Failure Patients In A Tertiary Care Hospital, West Nusa Tenggara, Indonesia, Dita Marina Lupitaningrum, Putri Ramdaniah, Depi Yuliana

Pharmaceutical Sciences and Research

Congestive Heart Failure (CHF) is a progressive health problem with high mortality and morbidity and has the potential to develop adverse drug reactions (ADRs). This study was conducted to determine the prevalence of potential ADRs, the types of drugs that cause ADRs, the types of ADRs, and the risk factors that affect the ADRs in CHF patients. Data were collected using medical record of hospitalized patient at the West Nusa Tenggara (NTB) Provincial Hospital, Indonesia, in 2017 to 2019. The assessment of the causality and severity of ADRs used the Naranjo algorithm and the Hartwig and Siegel scale. This study …

Comprehensive In Silico Analysis Of Christinin Molecular Behaviour From Ziziphus Spina-Christi Leaves On Propionibacterium Acnes, Fitrianti Darusman, Taufik Muhammad Fakih

Pharmaceutical Sciences and Research

The role of in silico studies in the discovery of new drugs is very important and interesting in the recent years, where the results can be used as confirmation of the results of in vitro tests carried out experimentally in the laboratory. One of the herbal ingredients is Ziziphus spina-christi leaves with effective antibacterial activity, such as for acne-causing bacteria, namely Propionibacterium acnes. This is because it contains main secondary metabolites with saponins as the major components which contain christinin as its active compound. There are four known types of christinin, namely christinin-A, christinin-B, christinin-C, and christinin-D. In this …

A Review: Composition Of Neonatal Meconium Microbiota And Its Role For Potential Probiotic, Devi Oktaviyani, Raden Zulfa 'Alawiyyah, Putri Nusaiba, Amarila Malik

Pharmaceutical Sciences and Research

Early-life period (≤ 1 month after birth) is critical for determining long- and short-term health of neonates. Composition of neonates’ gut microbiota varies greatly between individuals whose development is influenced by various factors including differences in maternal diet and lifestyle during pregnancy, related to population and ethnicity. Balanced microbial composition can create symbiosis among commensal microbes, immunomodulatory compound production, and subsequent immune response regulation. Unbalanced microbiota composition, characterized by more pathogenic organism, less diversity, and less resistance to disease, is called dysbiosis. Probiotic bacteria are a bacteria group contributing to the balance of neonates’ gut microbiota. Probiotic bacterial strains, such …

Interpersonal Relationship And Its Effect On Treatment Compliance In Patients With Type-2 Diabetes Mellitus, Fransiskus Samuel Renaldi, Woro Riyadina, Muhammad Qamar, Rani Sauriasari

Pharmaceutical Sciences and Research

Type-2 diabetes mellitus has become a chronic disease that can lead to serious complications and can only be prevented by compliant treatment of the patients. Compliance can be influenced by various factors, one of which is interpersonal factors. This study aimed to identify various interpersonal relationship problems between patients and healthcare workers that can affect their treatment compliance behavior. This study employed a qualitative design with phenomenological methods. This research was conducted in Central Bogor City in March-August 2020. The data were collected by conducting in-depth interviews with 20 type-2 diabetes mellitus patients who had been confirmed by the Community …

Drug Repurposing And Dosage Form Development Of Anti-Covid-19, Kevin Kwok

Pharmaceutical Sciences and Research

The COVID-19 pandemic has been occurring approximately for more than 1 year. This pandemic has been a health issue that hits all countries in the world caused by the transmission of SARS-CoV-2 virus from one individual to another. The symptoms showed from the infected are fever, shortness of breath, dry cough, headache, and sore throat, among others. The SARS-CoV-2 virus is transmitted through sneezing, coughing, talking, and touching infected objects. Along with this transmission, the SARS-CoV-2 virus will continue to mutate. This mutation becomes an obstacle as well as a challenge to find drugs that can overcome the SARS-CoV-2 virus …

Preliminary Characterization, Antioxidant And Antiproliferative Properties Of Polysaccharide From Caulerpa Taxifolia, Ariane Marie Bayro, Joanne Katherine Manlusoc, Renaliza Alonte, Catherine Caniel, Patrick Conde, Carlo Embralino

Pharmaceutical Sciences and Research

Macroalgae are abundant sources of bioactive polysaccharides and prospective candidates for effective and non-toxic substances. This study aims to preliminary characterize and determine the in vitro antioxidant activity and cancer cell growth inhibitory activity against human lung adenocarcinoma cell (A549) of the polysaccharide from an invasive green alga, Caulerpa taxifolia. Crude polysaccharide (CP) was extracted from the dried algal sample of C. taxifolia by hot water extraction followed by absolute ethanol precipitation. CP was subjected to preliminary chemical characterization, including protein, carbohydrate, and sulfate content analysis by Kjeldahl titrimetry, acid hydrolysis, gravimetry, and ashing-acid water digestion ion chromatography, respectively. …

Puasa Ramadan Dan Diabetes Melitus: Risiko, Manfaat Dan Peluang Penelitian, Dicky L Tahapary, Syahidatul Wafa, Dante S. Harbuwono

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Cloning Of Pe11 (Lipx, Rv1169c) Gene Of Mycobacterium Tuberculosis Beijing Strain To Pcdna3.1 Plasmid Vector, Lulut Azmi Supardi, Andriansjah Rukmana, Fithriyah Sjatha

Makara Journal of Science

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. It is a persistent global health problem with a high mortality rate. Currently, TB is controlled by administering the Bacillus Calmette-Guerin (BCG) vaccine, but the effectiveness of its protection varies among individuals in a population. The pe/ppe gene family comprises a typical group of genes that play a role in avoiding the host immune response and inducing persistent TB infection. Based on in silico analysis, the pe11 gene has estimated immunogenicity and potential as a TB seed vaccine candidate. The pe11 gene from an Indonesian isolate of an M. …

The Pattern Of Microorganism On Adult Acute Leukemia Patientsduring Bacterial Surveillance And Febrile Neutropenia At Ciptomangunkusumo Hospital, Lugyanti Sukrisman

Jurnal Penyakit Dalam Indonesia

Introduction. The standard intensive chemotherapy in acute leukemia patients will cause severe neutropenia and infection (febrile neutropenia) with high fatality rate. The availability of accurate data on causative pathogens is essential to the appropriate selection of empirical therapy and usually obtained from bacterial surveillance. This study was intended to evaluate bacterial pathogens found on surveillance and during febrile neutropenia in acute leukemia patients undergoing chemotherapy at Cipto Mangunkusumo Hospital and to provide information for antimicrobial policy in the hospital. Methods. A retrospective study from data of bacterial surveillance of acute leukemia patients undergoing chemotherapy during 2008-2010 in isolation room for …

Management Of Diabetic Ketoacidosis In Patient With Heartfailure, Dicky Febrianto, Est Hindariati

Jurnal Penyakit Dalam Indonesia

Diabetic ketoacidosis (DKA) is diabetes mellitus emergency which is defined by the biochemical triad of hyperglycemia, ketonemia, and acidemia. Diabetic ketoacidosis continues to have high rates of morbidity and mortality despite advances in the treatment of diabetes. Crucial aspects of DKA management involve adequate replacement of fluids and electrolytes, particularly potassium, and the continuous administration of insulin. Hydration status in patients with DKA and heart failure can be assessed by physical examination, such as consciousness, vital signs, capillary refill time, skin turgor, jugular venous pressure, and signs of pulmonary edema. Invasive and non-invasive methods can also assess fluid adequacy in …