Medicine and Health Sciences Commons^™

Increasing Hpv Vaccination Rates Using Social Marketing Strategies, Sharon Wilson Catledge

Doctoral Projects

The human papillomavirus (HPV) is the most common sexually-transmitted infection (STI). Approximately 20 million Americans between the ages of 15 and 49 years currently have HPV with > 6.2 million new HPV infections estimated to occur each year. Yet, HPV vaccination rates remain relatively low. More than 40 strains of HPV are transmitted through genital contact during vaginal, anal, or oral sex and can infect males and females. In addition to causing genital warts, HPV is associated with cervical, vulvar, vaginal, anus, penile, and oropharyngeal cancers. In women, the most prominent type of cancer is cervical with > 12,000 diagnoses each year …

Evaluating The Perceptions Of Quality Of Life In Informal Caregivers Caring For Hospice Patients, Rashandra Fisher Laws

Doctoral Projects

Maintaining or improving quality of life for informal caregivers is important as they endure the burden of providing care to terminally ill loved ones on a daily basis. Caregivers are at a greater risk for depression, deteriorating physical health, financial difficulties, and premature death than demographically similar non-caregivers (Demiris et al., 2010). The goal of this capstone project was to determine the effectiveness of the creativity, optimism, planning, and expert information (COPE) intervention, which address specific needs of the family and caregiver.

Twenty informal caregivers completed the Quality of Life (QoL) Index tool, which measured their perceptions of five different …

An Evaluation Of Fall Prevention Interventions Among Older Adults In A Long Term Care Facility, Courtney Anita Bennett

Doctoral Projects

Falls are serious unwanted events that are a common occurrence among older adults in long term care facilities (LTC). Fall prevention in LTC facilities requires the efforts of an interprofessional team that promotes safety within an organization. The purpose of this capstone project is to implement and evaluate evidence-based fall prevention interventions at a LTC facility. Specific objectives of the project include: (a) providing education to healthcare professionals on evidence-based practices to recognize, assess, and prevent falls among older adults in a long term care facility and (b) replacing the existing fall prevention policy and program with a falls and …

Psychiatric Mental Health Nurse Practitioner Workforce Development In Behavioral Healthcare Settings In Rural Mississippi, Arlen Davis Cooper

Doctoral Projects

Description and Significance of the Problem: The United States is facing a significant rural mental healthcare workforce shortage and an uneven distribution of mental healthcare professionals. The psychiatric mental health nurse practitioner (PMHNP) may increase access to mental healthcare in rural underserved regions (NRHA, 2012). However, little is known regarding their distribution. The lack of uniform and consistent data collection methods regarding the number and the geographic distribution of PMHNPs in rural areas, specifically in rural Mississippi, exists. The importance of better data collection and improving infrastructure through collaboration with state licensing boards and state nursing workforce centers is …

Integrating A System Approach To Identify And Manage Aggressive Behaviors In Adult Males With Severe Mental Illness In A Psychiatric Hospital, Mitzie Alford-Jenkins

Doctoral Projects

Aggressive behaviors exhibited by patients with a serious mental illness (SMI) hospitalized in inpatient psychiatric hospitals are a challenging safety problem. Early identification of aggressive behaviors is vital to helping nursing staff develop proactive interventions that focus on prevention. Structured risk assessments identify the level of risk and allow for early interventions.

The purpose of the doctoral capstone project was to: (a) provide education to nursing staff on implementing a structured risk assessment tool in order to identify risk for imminent aggression, manage risk for imminent aggression, and record aggressive behaviors among adult males with severe mental illness (SMI); (b) …

The Effects Of The Tootling Intervention Using Daily Reinforcement, Melissa Bryanne Mchugh

Master's Theses

The current study was designed to replicate and extend the literature on the effectiveness of a classroom intervention known as Tootling (Skinner, Skinner, & Cashwell, 1998) in decreasing disruptive classroom behavior as well as increasing academically engaged classroom behavior. Tootling is a strategy that encourages and prompts students to report instances of their peers’ positive behaviors. Thus far, only three studies have utilized direct observation data for disruptive behavior during Tootling (Cihak, Kirk, & Boon, 2009; Lambert, 2012, 2014). To extend the research on Tootling, direct observation data of disruptive and academically engaged behaviors were collected on both entire classes …

Nurse Knowledge Of Clostridium Difficile, Ashley E. Frosch

Honors Theses

The purpose of this study is to determine the amount of knowledge nurses have about Clostridium difficile. Seventy-five nurses participated in this study. A 25-question true/false survey was distributed via email to graduates of The University of Southern Mississippi. The survey consisted of a brief demographic section and 25 questions addressing Clostridium difficile knowledge. A total of 582 surveys were sent out with a total of 75 completed. Out of 25 questions in the survey, the majority of respondents (>50%) only answered 7 questions incorrectly. Overall, the nurses in this study possessed accurate knowledge about C. difficile; although, there …

Physical Fitness And Body Mass Index As Predictors Of Academic Achievement, Kristin V. Sumrall

Honors Theses

In the United States, a significant portion of the population is overweight or obese. In addition to this, there are very low levels of physical fitness amongst the general population. However, in numerous studies healthy body weight and moderate to high levels of physical fitness have been linked with many benefits, including improved academic performance. This study focused on the relationship between physical fitness, body mass index, and academic achievement in college students at the University of Southern Mississippi. The aim of this study was to conduct a quantitative correlational analysis of these three factors in order to determine if …

Utilizing Landsat Tm And Oli In Predicting Oncomelania Hupensis Habitats Around Poyang Lake Before And After Three Gorges Dam Completion, Stephanie L. Mccracken

Honors Theses

Schistosomiasis is a parasitic disease caused by the Schistomsoma japonicum flatworm that utilizes the Oncomelania hupensis snail as an intermediate agent. In the People’s Republic of China, these amphibious snails contaminate freshwater systems infecting humans, bovines, and other mammals and have caused significant morbidity for over two thousand years (Wertheim, et al. 2012; Zhang, et al. 2012.) The gravity of this disease prompted the national government to initiate sizable public health programs, such as the World Bank Loan Project (WBLP.) In spite of WBLP's achievements, in 2004, after this program ended, a national survey acknowledged a resurgence of schistosomiasis in …

Tuning Responsiveness Of Polypeptide Based Block Copolymers For Drug Delivery, Ashley J. Johnson

Dissertations

The goal of this dissertation was to tune the pH response and self-assembled morphologies of amphiphilic polypeptide block copolymers for use as drug delivery vehicles. Poly(L-lysine) and poly(L-glutamtic acid) are responsive, ionizable polypeptides that undergo secondary structure transitions, from α-helix to random coil, whereby the change in conformation of the peptide chain results in changes to the global morphology of a self-assembled system. The main focus of this work was to understand how changes in the polymer composition and the local environment can lead to control over the behavior of the overall system. First, the responsive behavior of poly(L-lysine) block …

Self-Propagative Replication Of Aβ Oligomers Suggests Potential Transmissibility In Alzheimer Disease, Amit Kumar, Kayla M. Pate, Melissa A. Moss, Dexter N. Dean, Vijayaraghavan Rangachari

Faculty Publications

The aggregation of amyloid-β (Aβ) peptide and its deposition in parts of the brain form the central processes in the etiology of Alzheimer disease (AD). The low-molecular weight oligomers of Aβ aggregates (2 to 30 mers) are known to be the primary neurotoxic agents whose mechanisms of cellular toxicity and synaptic dysfunction have received substantial attention in the recent years. However, how these toxic agents proliferate and induce widespread amyloid deposition throughout the brain, and what mechanism is involved in the amplification and propagation of toxic oligomer species, are far from clear. Emerging evidence based on transgenic mice models indicates …

Brief Intervention For Truant Youth Sexual Risk Behavior And Marijuana Use, Richard Dembo, Rhissa Briones-Robinson, Kimberly Barrett, Rocio Ungaro, Ken C. Winters, Steven Belenko, Lora M. Karas, Laura Gulledge, Jennifer Wareham

Faculty Publications

Substance use and sexual risk behaviors are common among adolescents, but research has focused attention on alcohol use. Much less is known about the relationship of marijuana use and sexual risk behavior among high-risk, especially truant, youths. We report interim findings from a NIDA-funded experimental, brief intervention (BI) study involving truant youths and their parents/guardians. Longitudinal data were analyzed to study (1) the relationships between the youths' marijuana use and sexual risk behavior and (2) the effects of a substance use BI on their marijuana use and sexual risk behavior. A growth model analysis for parallel processes was conducted to …

Re-Engineered Discharge Planning In A Rural Mississippi Hospital To Reduce 30 Day Readmission Rates Among Heart Failure Patients, Roxie Mae Hogan

Doctoral Projects

The hospital discharge is a complex process that involves interdisciplinary efforts to avoid readmissions and decrease health care costs. The purpose of this capstone project was to take a leadership role in translating evidence into practice by successfully preparing NWMRMC discharge planning stakeholders to adapt Project RED for use with HF patients admitted to NWMRMC.

A comprehensive systematic improvement plan, Project RED is designed to improve the work flow process through the use of timelines and strategies. Project RED supports discharge planning, helps to prevent readmission, and facilitates knowledge transfer that promotes sustainable changes. Re-Engineered Discharge Planning (RED), 6 step …

Self-Assembled Gold Nanoplexes For Cancer-Targeted Sirna Delivery, Yongliang Shi

Master's Theses

Through layer-by-layer method, the authors have constructed three Au nanoplexes: AuPEI/RNA/PEI, AuPEI/RNA/PEI-mPEG, and AuPEI/NA/PEI-PEG-FA. All the nanoplexes are characterized by UV-vis spectrometry, DLS, and zeta potential. The surface density of the first layer PEI and second layer RNA were also determined. Moreover, the Au nanoplexes can protect siRNA from RNase degradation and are stable in cell culture medium.

siGLuc-ppp, ssRNA₈₀, and siF17 were delivered by the assembled Au nanoplexes, and the results were analyzed by GLuc assay, TB assay, and Luciferase assay. In terms of RNA delivery, the Au nanoplexes AuPEI/RNA/PEI exhibited excellent gene silencing efficiency (or causing …

Dispositional Optimism: Modeling Cardiovascular Disease Mortality With Traditional Risk Factors And A Psychosocial Personality Trait, Kiana Ramisi Luckett Robinson

Dissertations

Despite increased awareness of clinical risk factors for cardiovascular disease (CVD), heart disease remains a physical and economic burden to African Americans. The aim of this study was to investigate the relationship between dispositional optimism, a psychosocial personality trait, and CVD mortality, based on immediate cause of death. A cross-sectional design was used to examine the predictive value of dispositional optimism in CVD mortality concomitant with traditional CVD risk factors. The traditional CVD risk factors of interest consisted of body mass index, waist circumference, systolic and diastolic blood pressures, total cholesterol, and C-reactive protein. Also, aggregated mortality data for optimists …

Influence Of Resources, Resource Loss, And Coping Response On Food Management Practices And Food Security, Simone Perette Camel

Dissertations

Food insecurity has been associated with compromised health and wellness. Current literature regarding coping strategies and practices employed by the food insecure often describes food management and acquisition practices, and/or the riskiness of these practices. Material and personal resources such as income, time, self-efficacy, and social support have been identified as predictors or influencers of food security status. In this study, the Conservation of Resources theory was used to conceptualize resources and resource loss as they relate to food practices and food security. It was hypothesized that the level of resources would influence food security status and the adaptive food …

Fluorine Containing Uv-Curable Materials For Advanced Transport Applications, James Thomas Goetz

Dissertations

The characterization of structure, thermal, gas transport, and free volume properties of two unique UV cured polymeric systems are studied and reported. In the initial pursuit of waterproof high water vapor transport membranes, it became apparent that the UV curing of fluorinated materials yielded routes to develop unique materials that fundamentally challenge conventional models for free volume and light gas transport behavior. UV-curing provides a means to rapidly “lock-in” morphologies that are accessible in the small molecule, monomer phase but rapidly become kinetically inaccessible when constraints such as covalent bonding and cross linking limit motion in the polymer system. This …

Opinions Of South Mississippi College Students Regarding Adolescent Sex Education, Mary K. Nobles

Honors Theses

Teen pregnancy and rates of sexually transmitted disease (STD) transmission among teenage Mississippians are disproportionally higher than the national average. These high rates are partially attributed to poor adolescent sex education programs in Mississippi (MS) schools. MS has a long history of inadequate sex education programs; until recently, sex education was not a required component of the curriculum. Most MS public schools teach abstinence-only education, which has been shown to be less effective than comprehensive programs. Most Mississippians probably assume that MS public schools teach the sex education programs of which the majority of Mississippians are in favor. A review …

Promoting Behavior Changes In Patients With Type 2 Diabetes Through Shared Medical Appointments, Shonda Lanette Williams

Doctoral Projects

Diabetes Mellitus (DM) is a chronic disease that affects many individuals in the United States. It was reported that a total of $245 billion is spent annually on both direct and indirect health care costs associated with the treatment of diabetes and diabetic related complications. Diabetes related complications can be prevented or delayed if proper education is done and individuals are willing to practice positive behavior changes and self-manage their disease. The purpose of this doctoral capstone project was to promote behavior changes in patients with diabetes through diabetes self-management education (DSME) in shared medical appointments (SMAs).

This project was …

Bridging The Gap: Understanding, Anticipating, And Responding To The Needs Of Student Veterans In A Bachelor Of Science In Nursing Program, Larry Michael Stowers

Doctoral Projects

The passage of the Americans with Disabilities Act Amendment Act (ADAAA) of 2008 and the Post-9/11 Veterans Assistance Act of 2008 have afforded veterans the opportunity to pursue post-secondary education. Since October 2001, over 2 million American men and women in uniform have deployed in support of Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF). While thousands of returning combat veterans take advantage of recent legislation that helps pay for their education, they face new challenges in the classroom. This nation’s veterans represent a group of diverse individuals who bring different experiences, thus different perspectives than traditional college-aged students. …

An Evaluation Of The Effectiveness Of Providing Foot Care Education In A Rural Clinic Setting, Gloria Green-Morris

Doctoral Projects

Diabetes is one of the most frequently diagnosed metabolic disorders and is currently at pandemic magnitude. Approximately 1.4 million adults are diagnosed with diabetes each year. According to the American Diabetes Association (2011), the numbers of diagnoses will more than double by 2030. Because of the high prevalence of diabetes, the perceptions of risk factors and healthy behaviors are important. A good understanding of written and verbal healthcare instructions, healthcare accessibility, and socio-economic status have a direct effect on patient health outcomes and the overall health of the population (Jovic-Vranes, Bjegovic-Marinkovic & Marinkovic, 2009).

Diabetic foot complications are common concerns …

Evaluation Of A Theory-Based Farm To School Program, Rebecca Kent Bishop

Master's Theses

Fruit and vegetable (FV) intakes in MS children remain lower than recommended. Theory-based, multi-component nutrition education interventions like Farm to School (F2S) target FV consumption and utilize such interventions to improve children’s dietary behaviors by incorporating nutrition and agriculture education. The current study was designed with Theory of Planned Behavior (TPB) as its framework. An intervention was implemented to enhance beliefs, norms, and self-efficacy regarding FV, thus potentially increasing the intention to consume more FV. The research objectives of this study are to describe changes over the course of the intervention in (1) nutrition knowledge; (2) norms, beliefs, and self-efficacy …

Propagation Of Oligomeric Α-Synuclein And Amyloid-Β: Implications For Parkinson's And Alzheimer's Diseases, Matthew Stephen Planchard

Master's Theses

The aggregation of amyloidogenic proteins is a critical event in the pathology of a variety of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The proteins α-synuclein (αS) and amyloid-β (Aβ) are involved in the formation of amyloid lesions observed in PD and AD, respectively. Both PD and AD exhibit a significant amount of co-pathology in clinical settings, and the αS and Aβ proteins have been shown to interact in vitro. Recent experimental consensus has shown oligomeric species to be significant, if not primary, sources of toxicity in these diseases. …

Awareness, Education, And Prevention Of Chronic Kidney Disease In The Older Adult, Torrel R. Bridges

Honors Theses

Chronic kidney disease (CKD) has become a major issue in our nation. Many of our neighbors, family, and friends have concerns and a call for our attention is necessary. CKD does not have a specific target, but individuals with diseases such as diabetes mellitus, cardiovascular disease, and obesity are all at increased risk. Adults older than 65 years of age are especially at increased risk for developing CKD due to decrease in kidney function and other physiologic changes. In light of this, awareness, education, and prevention of CKD in the older adult population is important.

The number of older individuals …

Body Mass And Depression Among Mississippi Women With Polycystic Ovarian Syndrome, Laurel A. Bruce

Honors Theses

Objective

The purpose of this study is to evaluate the relationship between body mass and depression among Mississippi women with polycystic ovarian syndrome (PCOS).

Methods

Ten women participated in this study. Data was collected by online survey. The survey was distributed to eligible participants on pcoschallenge.com, a support network for women with PCOS. The survey included the Center for Epidemiologic Studies Depression (CES-D) questionnaire as well as five additional questions that asked the participants to report their weight, height, comorbidities, age, and race. The CES-D score provided a measurement for depression while the participant’s weight and height allowed the researcher …

The Comparison Of The Effectiveness Of Using A Traditional Approach To Speech Therapy To Using A Traditional Approach To Speech Therapy Plus Non-Speech Oral Motor Exercises In Children With Articulation Disorders, Alanna D. Buckley

Honors Theses

This study focuses on an area of debate in the field of Speech-Language Pathology with little prior research on the topic. The thesis considers the use of non-speech oral motor exercises in children with Articulation Disorders. Understanding the reasoning behind the use of these exercises as well as the reasons that cause the exercises to be controversial are discussed. Data is collected from four clients at the University of Southern Mississippi Speech and Hearing Clinic. All four clients have Articulation Disorders; non-speech oral motor exercises are used in therapy with two of the clients in addition to a Traditional Approach …

Does Knowledge Make A Difference? Assessing Nursing Students’ Knowledge Of Proper Hand Hygiene Techniques In Correlation With Their Progression Through Nursing School, Charika R. Carradine

Honors Theses

Proper hand hygiene techniques have been widely accepted as the most effective way for health care workers to prevent the spread of diseases. The main focus of this research was to determine differences between nursing students’ semester level and their knowledge of proper hand hygiene techniques. A convenience sample was obtained from the nursing student population. The sample population included nursing students enrolled in the second, third, and fourth semester in nursing school. Data collected was analyzed using SPSS version Twenty. A Parametric and descriptive statistics were used to measure the magnitude of relationships between variables, and describe students’ knowledge …

Solving The Obesity Problem One Bite At A Time: A Review Of Interventions, Sally Catherine Davis

Honors Theses

Resource limitations contribute to obesity in southern rural populations. An examination of published research provides evidence related to factors that lead to obesity and to related health consequences. Resource limitations in southern rural areas include a lack of access to healthy foods, a lack of safe areas to exercise or fitness equipment, and a lack of funding to promote the hiring of adequate numbers of healthcare workers to implement prevention programs and treat obesity related diseases. An investigation of obesity rates in Mississippi and Louisiana demonstrate that high rates of obesity exist. Through an exploration of published interventions in both …

Humor As A Buffer For Stress In Nurse Anesthesia Students, Kayla C. Forbis

Honors Theses

This simple, quantitative study was carried out on 18, first-year, CRNA students to determine if humor could act as a buffer for some of his or her perceived stress. Before an impending final exam, when stress levels would most likely be at their highest, the students were broken into three groups: a control group, a non-humorous group, and a humorous group. The students in the control group ranked their level of stress on a 0-10 scale without any other intervention. The other two groups watched a video clip, either humorous or non-humorous, while ranking their perceived stress on a scale …

“Birth Order’S Effect On Language Delay Detection In Young Children”, Victoria C. Souhlas

Honors Theses

In the field of Speech-Language Pathology, research has shown that the earlier a child is diagnosed with a speech and language disorder, the better the prognosis is for a favorable therapy outcome (Carroll, Bowyer-Crane, Duff, Hulme, Snowling, 2011). This researcher concentrated on how the birth order of a child can affect the prognosis of a speech and language delay. For this study, the goal was to collect quantitative data in order to view the extent of the correlation between birth order and the age of diagnosis. A sample population was found at the DuBard School of Language Disorders at the …