Medicine and Health Sciences Commons^™

Does Administration Of 800 Mg Intravenous Ibuprofen Reduce Post-Surgical Pain Within 24-28 Hours?, Marisa Mazza

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not administration of 800 mg IV ibuprofen reduces post-surgical pain within 24-28 hours.

Study Design: A systematic review of three randomized, double blind, placebo-controlled studies.

Data Sources: All studies were published in English during or after the year 2010. All articles were obtained from peer reviewed journals and databases using PubMed and CINAHL Plus. Selection was determined based on the relevance to the clinical question.

Outcomes Measured: All three studies aimed to measure the efficacy of IV ibuprofen on the reduction of post-operative pain at rest and …

Does Catheter Ablation Improve The Quality Of Life In Patients With Atrial Fibrillation Compared To Drug Therapy?, Ry’N Bland

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this evidence-based medicine (EBM) review was to determine whether or not catheter ablation improves quality of life in patients with atrial fibrillation compared to drug therapy.

STUDY DESIGN: Systematic review of three peer-reviewed studies published in the years 2018 and 2019. All three studies were published in English.

DATA SOURCES: Articles were selected based on their relevance to the clinical question. Additionally, all three studies placed emphasis on patient-oriented outcomes. The studies were selected via Pubmed and keyword searching. The first study selected and reviewed was an observational cohort study, the second study was a multi-center …

Does Mesalamine Decrease Abdominal Pain In Adults With Ibs?, Ruth Joanis

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this EBM review is to determine whether or not the use of mesalamine decreases abdominal pain in adults with IBS.

Study Design: Review of 3 randomized control trials.

Data Sources: All articles were published in English between 2012 and 2016. Articles were obtained from peer-reviewed journals using PubMed.

Outcomes: The outcome measured was the level or presence of abdominal and was measured via binary scale, 10-point visual analogue scale rated by patients on a 0 to 10 scale with 0 being no pain and 10 being the maximum level of pain and via patient symptom diary …

Is Levetiracetam More Effective Than Phenytoin In Seizure Cessation In Children With Convulsive Status Epilepticus That Don’T Respond To First-Line Treatment?, Sydney A. Santiago

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Is levetiracetam more effective than phenytoin in seizure cessation in children with convulsive status epilepticus that don’t respond to first-line treatment?”

Study design: Systematic review of three randomized controlled trials (RCTs) published in peerreviewed journals in English in 2019. Data Sources: Three RCTs published in peer reviewed journals were found using Alt HealthWatch, AMED, CINAHL Plus, and Scopus.

Outcome(s) Measured: Clinical cessation of seizure, defined as cessation of continuous rhythmic clonic activity, was measured by the investigator after infusion of treatment.

Results: The study by Dalziel …

Do Patients With A Ruptured Acl, Who Undergo A Hamstring Graft, Have Less Kneeling Pain Than Those Who Undergo A Patellar Tendon Graft?, Savannah Taranto

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Do patients with a ruptured ACL, who undergo a hamstring graft, have less kneeling pain than those who undergo a patellar tendon graft?”

STUDY DESIGN: A systematic review of three randomized controlled trials published after 2011 comparing the intervention of hamstring tendon graft to the patellar tendon graft.

DATA SOURCES: All three sources were obtained from PubMed based on its relevance to the clinical question, the publication date, as well as the inclusion/exclusion criteria.

OUTCOMES MEASURED: The outcome that is being measured is kneeling pain after …

Does Dupilumab Decrease The Amount Of Asthma Exacerbations In Patients Suffering From Asthma Compared To Placebo?, Rachel N. Campo

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this systematic EBM review is to determine “Does dupilumab decrease the amount of asthma exacerbations in patients suffering from asthma compared to placebo?”

STUDY DESIGN: A review of three randomized, placebo-controlled trials (RCTs) that were peer reviewed and published in English after 2009.

DATA SOURCE: All articles were published in peer reviewed journals and were researched using PubMed. Studies were selected based on their ability to answer the question posed in the objective, and if the researched outcomes were patient oriented.

OUTCOMES: Assessed outcomes were either the occurrence or rate of asthma exacerbations during the studies. …

Is Cognitive Behavioral Therapy (Cbt) Effective In Reducing Depressive And Manic Symptoms In People With Bipolar Disorder When Compared To Treatment As Usual (Tau)?, Shilo C. Dorley

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not cognitive behavioral therapy (CBT) is effective in reducing depressive and manic symptoms in people with bipolar disorder when compared to TAU.

STUDY DESIGN: Systematic review of three randomized controlled trials published in 2011, 2012, and 2014.

DATA SOURCES: Data sources for this review were articles published in peer-reviewed journals using PubMed and Cochrane Collaboration.

OUTCOME(S) MEASURED: The outcomes measured were a decrease in depressive and manic symptoms through the use of rating scales.

RESULTS: Costa et al. (2011) showed a greater decrease in depressive and manic …

Is Liraglutide Effective For Weight Loss In Adults Who Are Overweight Or Obese Compared To Placebo?, Shaina Yadav

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not is liraglutide effective for weight loss in adults who are overweight or obese compared to placebo.

STUDY DESIGN: Review of three double-blind, randomized controlled trials published after 2010.

DATA SOURCES: All three English language, double-blind, randomized controlled trials were found using PubMed. All three RCT’s were published in peer reviewed journals.

OUTCOMES MEASURED: The outcome measured was loss of 7% or more of body weight from baseline in the study by Sun et al., and loss of greater than 10% of body weight from baseline in …

Is Massage Therapy Effective In Reducing Labor Pain In Intrapartum Women?, Veronica K. Pham

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether massage therapy is an effective intervention in reducing pain in intrapartum women.

STUDY DESIGN: A systematic review of two randomized controlled trails (RCTs) and one case study published between 2009-2019. All studies were published in English.

DATA SOURCES: The two double-blind RCTs and case study were found via PubMed. All sources were published in peer reviewed journals and chosen based on their relevance to the clinical question.

OUTCOMES: Pain reduction was the outcome measured in all three studies using visual analog scale. In this systematic review, pain level …