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Does Edaravone Slow Disease Progression In Patients With Amyotrophic Lateral Sclerosis?, J. Michael Rutledge
Does Edaravone Slow Disease Progression In Patients With Amyotrophic Lateral Sclerosis?, J. Michael Rutledge
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this EBM review is to determine whether or not Edaravone is effective at slowing disease progression in patients with ALS.
Study Design: Review of three randomized control trials.
Data Source: All articles were published in English between 2014 and 2019. Articles were obtained from peer-reviewed journals and databases using Cochrane Collaboration, PubMed, Medline, and Embase.
Outcomes: The outcome measured was physical function assessed by the Amyotrophic Lateral Sclerosis Assessment and Questionnaire 40 Revised (ALSAQ-40R). Patients are asked to provide a perceived ability rating on a scale of 0 to 100, with 0 indicating perfect health and …