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Full-Text Articles in Medicine and Health Sciences

Personal Assessment Of The External Exposome During Pregnancy And Childhood In Europe [Accepted Manuscript], David Donaire Gonzalez, Ariadna Curto, Antònia Valentin, Sandra Andrusaityte, Xavier Basagaña, Maribel Casas, Leda Chatzi, Jeroen De Bont, Montserrat De Castro, Audrius Dedele, Berit Granum, Regina Grazuleviciene, Mariza Kampouri, Sarah Lyon-Caen, Cyntia B. Manzano-Salgado, Gunn Marit Aasvang, Rosemary R. C. Mceachan, Carin Helena Meinhard-Kjellstad, Eirini Michalaki, Pau Pañella, Inga Petraviciene, Per E. Schwarze, Rémy Slama, Oliver Robinson, Ibon Tamayo-Uria, Marina Vafeiadi, Dagmar Waiblinger, John Wright, Martine Vrijheid Jan 2019

Personal Assessment Of The External Exposome During Pregnancy And Childhood In Europe [Accepted Manuscript], David Donaire Gonzalez, Ariadna Curto, Antònia Valentin, Sandra Andrusaityte, Xavier Basagaña, Maribel Casas, Leda Chatzi, Jeroen De Bont, Montserrat De Castro, Audrius Dedele, Berit Granum, Regina Grazuleviciene, Mariza Kampouri, Sarah Lyon-Caen, Cyntia B. Manzano-Salgado, Gunn Marit Aasvang, Rosemary R. C. Mceachan, Carin Helena Meinhard-Kjellstad, Eirini Michalaki, Pau Pañella, Inga Petraviciene, Per E. Schwarze, Rémy Slama, Oliver Robinson, Ibon Tamayo-Uria, Marina Vafeiadi, Dagmar Waiblinger, John Wright, Martine Vrijheid

Faculty of Health Sciences Publications

The human exposome affects child development and health later in life, but its personal external levels, variability, and correlations are largely unknown. We characterized the personal external exposome of pregnant women and children in eight European cities. Panel studies included 167 pregnant women and 183 children (aged 6–11 years). A personal exposure monitoring kit composed of smartphone, accelerometer, ultraviolet (UV) dosimeter, and two air pollution monitors were used to monitor physical activity (PA), fine particulate matter (PM2.5), black carbon, traffic-related noise, UV-B radiation, and natural outdoor environments (NOE). 77% of women performed the adult recommendation of ≥150 min ...


Variability Of Urinary Concentrations Of Non-Persistent Chemicals In Pregnant Women And School-Aged Children, Maribel Casas, Xavier Basagaña, Amrit K. Sakhi, Line Smastuen Haug, Claire Philippat, Berit Granum, Cyntia B. Manzano-Salgado, Céline Brochot, Florence Zeman, Jeroen De Bont, Sandra Andrusaityte, Leda Chatzi, David Donaire-Gonzalez, Lise Giorgis-Allemand, Juan R. Gonzalez, Esther Gracia-Lavedan, Regina Grazuleviciene, Mariza Kampouri, Sarah Lyon-Caen, Pau Pañella, Inga Petraviciene, Oliver Robinson, Jose Urquiza, Marina Vafeiadi, Céline Vernet, Dagmar Waiblinger, John Wright, Cathrine Thomsen, Rémy Slama, Martine Vrijheid Jan 2018

Variability Of Urinary Concentrations Of Non-Persistent Chemicals In Pregnant Women And School-Aged Children, Maribel Casas, Xavier Basagaña, Amrit K. Sakhi, Line Smastuen Haug, Claire Philippat, Berit Granum, Cyntia B. Manzano-Salgado, Céline Brochot, Florence Zeman, Jeroen De Bont, Sandra Andrusaityte, Leda Chatzi, David Donaire-Gonzalez, Lise Giorgis-Allemand, Juan R. Gonzalez, Esther Gracia-Lavedan, Regina Grazuleviciene, Mariza Kampouri, Sarah Lyon-Caen, Pau Pañella, Inga Petraviciene, Oliver Robinson, Jose Urquiza, Marina Vafeiadi, Céline Vernet, Dagmar Waiblinger, John Wright, Cathrine Thomsen, Rémy Slama, Martine Vrijheid

Faculty of Health Sciences Publications

Background Exposome studies are challenged by exposure misclassification for non-persistent chemicals, whose temporal variability contributes to bias in dose-response functions. Objectives We evaluated the variability of urinary concentrations of 24 non-persistent chemicals: 10 phthalate metabolites, 7 phenols, 6 organophosphate (OP) pesticide metabolites, and cotinine, between weeks from different pregnancy trimesters in pregnant women, and between days and between seasons in children. Methods 154 pregnant women and 152 children from six European countries were enrolled in 2014–2015. Pregnant women provided three urine samples over a day (morning, midday, and night), for one week in the 2nd and 3rd pregnancy trimesters ...


Evaluation Of A Midwifery Initiated Oral Health-Dental Service Program To Improve Oral Health And Birth Outcomes For Pregnant Women: A Multi-Centre Randomised Controlled Trial, Ajesh George, Hannah G. Dahlen, Anthony Blinkhorn, Shilpi Ajwani, Sameer Bhole, Sharon Ellis, Anthony Yeo, Emma Elcombe, Maree Johnson Jan 2018

Evaluation Of A Midwifery Initiated Oral Health-Dental Service Program To Improve Oral Health And Birth Outcomes For Pregnant Women: A Multi-Centre Randomised Controlled Trial, Ajesh George, Hannah G. Dahlen, Anthony Blinkhorn, Shilpi Ajwani, Sameer Bhole, Sharon Ellis, Anthony Yeo, Emma Elcombe, Maree Johnson

Faculty of Health Sciences Publications

Background: Oral health care during pregnancy is important for the health of the mother and child. However, pregnant women have limited knowledge about maternal oral health and seldom seek dental care. Further, due to limited training antenatal care providers like midwives rarely discuss oral health with pregnant women. The Midwifery-Initiated Oral Health Dental Service program was developed to address current gaps in oral promotional interventions during pregnancy. Objectives: To assess the effectiveness of a Midwifery-Initiated Oral Health Dental Service program in improving uptake of dental services, oral health knowledge, quality of oral health, oral health status and birth outcomes of ...


The Cedar Project: Using Indigenous-Specific Determinants Of Health To Predict Substance Use Among Young Pregnant-Involved Indigenous Women In Canada, Sana Z. Shahram, Joan L. Bottorff, Nelly D. Oelke, Leanne Dahlgren, Victoria Thomas, Patricia M. Spittal Jan 2017

The Cedar Project: Using Indigenous-Specific Determinants Of Health To Predict Substance Use Among Young Pregnant-Involved Indigenous Women In Canada, Sana Z. Shahram, Joan L. Bottorff, Nelly D. Oelke, Leanne Dahlgren, Victoria Thomas, Patricia M. Spittal

Faculty of Health Sciences Publications

Background: Indigenous women in Canada have been hyper-visible in research, policy and intervention related to substance use during pregnancy; however, little is known about how the social determinants of health and substance use prior to, during, and after pregnancy intersect. The objectives of this study were to describe the social contexts of pregnant-involved young Indigenous women who use substances and to explore if an Indigenous-Specific Determinants of Health Model can predict substance use among this population. Methods: Using descriptive statistics and hierarchical logistic regression guided by mediation analysis, the social contexts of pregnant-involved young Indigenous women who use illicit drugs ...


Early Origins Of Mental Disorder: Risk Factors In The Perinatal And Infant Period, Louise Newman, Fiona Judd, Craig A. Olsson, David J. Castle, Chad Bousman, Penelope Sheehan, Christos Pantelis, Jeffrey M. Craig, Angela Komiti, Ian P. Everall Jan 2016

Early Origins Of Mental Disorder: Risk Factors In The Perinatal And Infant Period, Louise Newman, Fiona Judd, Craig A. Olsson, David J. Castle, Chad Bousman, Penelope Sheehan, Christos Pantelis, Jeffrey M. Craig, Angela Komiti, Ian P. Everall

Faculty of Health Sciences Publications

Background: There is increasing understanding of the significance of early neurodevelopment in establishing risk for the range of mental disorders. Models of the early aetiology of mental disorders are complex with a range of potential factors from genetic and epigenetic to environmental influencing neurological and psychological development. Whilst the mechanisms are not fully understood, this paper provides an overview of potential biological and neurobiological factors that might be involved. Method: An aetiological model is presented and discussed. The discussion includes a range of risk factors for mental disorder. Maternal anxiety disorder is presented and reviewed as an example of the ...


Measuring Oral Health During Pregnancy: Sensitivity And Specificity Of A Maternal Oral Screening (Mos) Tool, Ajesh George, Hannah G. Dahlen, Anthony Blinkhorn, Shilpi Ajwani, Sameer Bhole, Sharon Ellis, Anthony Yeo, Emma Elcombe, Ayesha Sadozai, Maree Johnson Jan 2016

Measuring Oral Health During Pregnancy: Sensitivity And Specificity Of A Maternal Oral Screening (Mos) Tool, Ajesh George, Hannah G. Dahlen, Anthony Blinkhorn, Shilpi Ajwani, Sameer Bhole, Sharon Ellis, Anthony Yeo, Emma Elcombe, Ayesha Sadozai, Maree Johnson

Faculty of Health Sciences Publications

Background: Being the parent of a severely injured child involves many stressors throughout the trauma journey. Internationally, little is known about the experiences or levels of emotional distress, parenting stress, quality of life, and resilience for parents of injured children. The aim of this study is to investigate the experiences, unmet needs and outcomes of parents of physically injured children 0–12 years over the 2 year period following injury. Methods/design: This is a prospective longitudinal study using an embedded mixed methods design. This design has a primary qualitative strand which incorporates supplementary quantitative data on child quality of ...


Maternal Occupation During Pregnancy, Birth Weight, And Length Of Gestation: Combined Analysis Of 13 European Birth Cohorts, M. Casas, Sylvaine Cordier, David Martínez, Henrique Barros, Jens Peter Bonde, Alex Burdorf, Nathalie Costet, Ana Cristina Dos Santos, Asta Danileviciute, Merete Eggesbø, Mariana F. Fernandez, Joelle Fevotte, Ana M. García, Regina Gražulevičienė, Eva Hallner, Wojciech Hanke, Manolis Kogevinas, Inger Kull, Pernille Stemann Larsen, Vasiliki Melaki, Christine Monfort, Karl-Christian Nordby, Anne-Marie Nybo Andersen, Evridiki Patelarou, Kinga Polanska, Lorenzo Richiardi, Loreto Santa Marina, Claudia Snijder, Adonina Tardón, M. Van Eijsden, T. G. M. Vrijkotte, D. Zugna, Mark J. Nieuwenhuijsen, M. Vrijheid Jan 2015

Maternal Occupation During Pregnancy, Birth Weight, And Length Of Gestation: Combined Analysis Of 13 European Birth Cohorts, M. Casas, Sylvaine Cordier, David Martínez, Henrique Barros, Jens Peter Bonde, Alex Burdorf, Nathalie Costet, Ana Cristina Dos Santos, Asta Danileviciute, Merete Eggesbø, Mariana F. Fernandez, Joelle Fevotte, Ana M. García, Regina Gražulevičienė, Eva Hallner, Wojciech Hanke, Manolis Kogevinas, Inger Kull, Pernille Stemann Larsen, Vasiliki Melaki, Christine Monfort, Karl-Christian Nordby, Anne-Marie Nybo Andersen, Evridiki Patelarou, Kinga Polanska, Lorenzo Richiardi, Loreto Santa Marina, Claudia Snijder, Adonina Tardón, M. Van Eijsden, T. G. M. Vrijkotte, D. Zugna, Mark J. Nieuwenhuijsen, M. Vrijheid

Faculty of Health Sciences Publications

Objectives: We assessed whether maternal employment during pregnancy – overall and in selected occupational sectors – is associated with birth weight, small for gestational age (SGA), term low birth weight (LBW), length of gestation, and preterm delivery in a population-based birth cohort design. Methods: We used data from > 200 000 mother-child pairs enrolled in 13 European birth cohorts and compared employed versus non-employed women. Among employees, we defined groups of occupations representing the main sectors of employment for women where potential reproductive hazards are considered to be present. The comparison group comprised all other employed women not included in the occupational sector ...


Environmental Risk Factors Of Pregnancy Outcomes: A Summary Of Recent Meta-Analyses Of Epidemiological Studies., Mark J. Nieuwenhuijsen, Payam Dadvand, James Grellier, David Martínez, Martine Vrijheid Jan 2013

Environmental Risk Factors Of Pregnancy Outcomes: A Summary Of Recent Meta-Analyses Of Epidemiological Studies., Mark J. Nieuwenhuijsen, Payam Dadvand, James Grellier, David Martínez, Martine Vrijheid

Faculty of Health Sciences Publications

Background Various epidemiological studies have suggested associations between environmental exposures and pregnancy outcomes. Some studies have tempted to combine information from various epidemiological studies using meta-analysis. We aimed to describe the methodologies used in these recent meta-analyses of environmental exposures and pregnancy outcomes. Furthermore, we aimed to report their main findings. Methods We conducted a bibliographic search with relevant search terms. We obtained and evaluated 16 recent meta-analyses. Results The number of studies included in each reported meta-analysis varied greatly, with the largest number of studies available for environmental tobacco smoke. Only a small number of the studies reported having ...


Maternal Exposure To Particulate Air Pollution And Term Birth Weight: A Multi-Country Evaluation Of Effect And Heterogeneity, Payam Dadvand, Jennifer Parker, Michelle L. Bell, Matteo Bonzini, Michael Brauer, Lyndsey A. Darrow, Ulrike Gehring, Svetlana V. Glinianaia, Nelson Gouveia, Eun-Hee Ha, Jong Han Leem, Edith H. Van Den Hooven, Bin Jalaludin, Bill M. Jesdale, Johanna Lepeule, Rachel Morello-Frosch, Geoffrey G. Morgan, Angela Cecilia Pesatori, Frank H. Pierik, Tanja Pless-Mulloli, David Q. Rich, Sheela Sathyanarayana, Juhee Seo, Rémy Slama, Matthew Strickland, Lillian Tamburic, Daniel Wartenberg, Mark J. Nieuwenhuijsen, Tracey J. Woodruff Jan 2013

Maternal Exposure To Particulate Air Pollution And Term Birth Weight: A Multi-Country Evaluation Of Effect And Heterogeneity, Payam Dadvand, Jennifer Parker, Michelle L. Bell, Matteo Bonzini, Michael Brauer, Lyndsey A. Darrow, Ulrike Gehring, Svetlana V. Glinianaia, Nelson Gouveia, Eun-Hee Ha, Jong Han Leem, Edith H. Van Den Hooven, Bin Jalaludin, Bill M. Jesdale, Johanna Lepeule, Rachel Morello-Frosch, Geoffrey G. Morgan, Angela Cecilia Pesatori, Frank H. Pierik, Tanja Pless-Mulloli, David Q. Rich, Sheela Sathyanarayana, Juhee Seo, Rémy Slama, Matthew Strickland, Lillian Tamburic, Daniel Wartenberg, Mark J. Nieuwenhuijsen, Tracey J. Woodruff

Faculty of Health Sciences Publications

Background: A growing body of evidence has associated maternal exposure to air pollution with adverse effects on fetal growth; however, the existing literature is inconsistent. Objectives: We aimed to quantify the association between maternal exposure to particulate air pollution and term birth weight and low birth weight (LBW) across 14 centers from 9 countries, and to explore the influence of site characteristics and exposure assessment methods on between-center heterogeneity in this association. Methods: Using a common analytical protocol, International Collaboration on Air Pollution and Pregnancy Outcomes (ICAPPO) centers generated effect estimates for term LBW and continuous birth weight associated with ...


Validation Of Trichloroacetic Acid Exposure Via Drinking Water During Pregnancy Using A Urinary Tcaa Biomarker, Rachel B. Smith, Mark J. Nieuwenhuijsen, John Wright, Pauline Raynor, John Cocker, Kate Jones, Maria Kostopoulou-Karadanelli, Mireille B. Toledano Jan 2013

Validation Of Trichloroacetic Acid Exposure Via Drinking Water During Pregnancy Using A Urinary Tcaa Biomarker, Rachel B. Smith, Mark J. Nieuwenhuijsen, John Wright, Pauline Raynor, John Cocker, Kate Jones, Maria Kostopoulou-Karadanelli, Mireille B. Toledano

Faculty of Health Sciences Publications

Disinfection by-product (DBP) exposure during pregnancy may be related to reduced fetal growth, but the evidence is inconclusive and improved DBP exposure assessment is required. The authors conducted a nested exposure study on a subset (n=39) of pregnant women in the Born in Bradford cohort to assess validity of TCAA exposure assessment based on tap water sampling and self-reported water-use; water-use questionnaire validity; and use of a one-time urinary TCAA biomarker. TCAA levels in urine and home tap water supply were quantified, and water use was measured via a questionnaire and 7-day diary, at 28 weeks gestation. Diary and ...


Body Image During Pregnancy: An Evaluation Of The Suitability Of The Body Attitudes Questionnaire, Matthew Fuller-Tyszkiewicz, Helen Skouteris, Brittany Elise Watson, Briony Hill Jan 2012

Body Image During Pregnancy: An Evaluation Of The Suitability Of The Body Attitudes Questionnaire, Matthew Fuller-Tyszkiewicz, Helen Skouteris, Brittany Elise Watson, Briony Hill

Faculty of Health Sciences Publications

Background Available data suggest that body dissatisfaction is common during pregnancy and may even be a precursor to post-natal depression. However, in order to accurately identify at-risk women, it is essential to first establish that body image measures function appropriately in pregnant populations. Our study examines the suitability of the Body Attitudes Questionnaire (BAQ) for measuring body dissatisfaction among pregnant women by comparing the psychometric functioning of the BAQ: (1) across key phases of pregnancy, and (2) between pregnant and non-pregnant women. Methods A total of 176 pregnant women from Melbourne, Victoria filled out a questionnaire battery containing demographic questions ...


Surrounding Greenness And Exposure To Air Pollution During Pregnancy: An Analysis Of Personal Monitoring Data, Payam Dadvand, Audrey De Nazelle, Margarita Triguero-Mas, Anna Schembari, Marta Cirach, Elmira Amoly, Francesc Figueras, Xavier Basagaña, Bart Ostro, Mark J. Nieuwenhuijsen Jan 2012

Surrounding Greenness And Exposure To Air Pollution During Pregnancy: An Analysis Of Personal Monitoring Data, Payam Dadvand, Audrey De Nazelle, Margarita Triguero-Mas, Anna Schembari, Marta Cirach, Elmira Amoly, Francesc Figueras, Xavier Basagaña, Bart Ostro, Mark J. Nieuwenhuijsen

Faculty of Health Sciences Publications

Background: Green spaces are reported to improve health status, including beneficial effects on pregnancy outcomes. Despite the suggestions of air pollution–related health benefits of green spaces, there is no available evidence on the impact of greenness on personal exposure to air pollution. Objectives: We investigated the association between surrounding greenness and personal exposure to air pollution among pregnant women and to explore the potential mechanisms, if any, behind this association. Methods: In total, 65 rounds of sampling were carried out for 54 pregnant women who resided in Barcelona during 2008–2009. Each round consisted of a 2-day measurement of ...