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Australian Catholic University

2017

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Articles 1 - 30 of 332

Full-Text Articles in Medicine and Health Sciences

Self-Reported Concussion History And Sensorimotor Tests Predict Head/Neck Injuries [Accepted Manuscript], Julie Anne Hides, Melinda M. Franettovich Smith, M Dilani Mendis, Julia Treleaven, Andrew H. Rotstein, Christopher T. Sexton, Nancy Low Choy, Paul Mccrory Dec 2017

Self-Reported Concussion History And Sensorimotor Tests Predict Head/Neck Injuries [Accepted Manuscript], Julie Anne Hides, Melinda M. Franettovich Smith, M Dilani Mendis, Julia Treleaven, Andrew H. Rotstein, Christopher T. Sexton, Nancy Low Choy, Paul Mccrory

Faculty of Health Sciences Publications

Sports related concussion (SRC) is a risk for players involved in high impact, collision sports. A history of SRC is a risk factor for future concussions, but the mechanisms underlying this are unknown. Despite evidence that most visible signs and symptoms associated with sports concussion resolve within 7-10 days, it has been proposed that subclinical loss of neuromuscular control and impaired motor functioning may persist and be associated with further injury. Alternatively, indicators of poor sensorimotor performance could be independent risk factors. This study investigated if a history of SRC and/or pre-season sensorimotor performance predicted season head/neck injuries ...


Muscle Force Contributions To Knee Joint Loading, Nirav Maniar Dec 2017

Muscle Force Contributions To Knee Joint Loading, Nirav Maniar

Theses

Anterior cruciate ligament (ACL) injuries are one of the most common knee injuries suffered by athletic populations. ACL injuries are particularly burdensome due to potential surgical requirements, extensive rehabilitation time and associated financial costs for the individual and the community. Additionally, ACL injuries are associated with increased risk of early onset knee osteoarthritis. As such, ACL injury preventative and rehabilitative strategies are of paramount importance.

ACL injuries typically occur during non-contact dynamic tasks, such as unanticipated sidestep cutting. At the time of injury, the knee joint experiences relatively large degrees of knee valgus and rotation (either internal or external) and ...


Self-Concept Of Children With Cerebral Palsy, Sau Kuan Cheong Nov 2017

Self-Concept Of Children With Cerebral Palsy, Sau Kuan Cheong

Theses

Self-concept is the perception that individuals have of themselves across different aspects of life such as academic performance or appearance. The Self-Concept Feedback Loop proposed for this research program conceptualised self-concept as developing through an interactive and iterative process involving social experiences and the cognitive processes of individuals. Through this process, individuals evaluate their behaviour or attributes against their internal standards. Subsequently, this evaluation influences their self-concept. In the general population, low self-concept has been linked to a range of negative outcomes, including poor academic achievement, and behaviour and mental health problems. However, research into the self-concept of children with ...


Design, Synthesis And Biological Activity Of 1,2,3-Triazolobenzodiazepine Bet Bromodomain Inhibitors [Accepted Manuscript], Phillip P. Sharp, Jean-Marc Garnier, Tamas Hatfaludi, Zhen Xu, David Segal, Kate E. Jarman, Helene Jousset, Alexandra Garnham, John Feutrill, Anthony Cuzzupe, Peter Hall, Scott Taylor, Carl R. Walkley, Dean Tyler, Mark A. Dawson, Peter Czabotar, Andrew F. Wilks, Stefan Glaser, David C. Huang, Christopher J. Burns Nov 2017

Design, Synthesis And Biological Activity Of 1,2,3-Triazolobenzodiazepine Bet Bromodomain Inhibitors [Accepted Manuscript], Phillip P. Sharp, Jean-Marc Garnier, Tamas Hatfaludi, Zhen Xu, David Segal, Kate E. Jarman, Helene Jousset, Alexandra Garnham, John Feutrill, Anthony Cuzzupe, Peter Hall, Scott Taylor, Carl R. Walkley, Dean Tyler, Mark A. Dawson, Peter Czabotar, Andrew F. Wilks, Stefan Glaser, David C. Huang, Christopher J. Burns

Faculty of Health Sciences Publications

A number of diazepines are known to inhibit bromo- and extra-terminal domain (BET) proteins. Their BET inhibitory activity derives from the fusion of an acetyl-lysine mimetic heterocycle onto the diazepine framework. Herein we describe a straightforward, modular synthesis of novel 1,2,3-triazolobenzodiazepines and show that the 1,2,3-triazole acts as an effective acetyl- lysine mimetic heterocycle. Structure-based optimization of this series of compounds led to the development of potent BET bromodomain inhibitors with excellent activity against AF9-MLL-driven leukemic cells, concomitant with a reduction in c-MYC expression. These novel benzodiazepines therefore represent a promising class of therapeutic BET inhibitors


Teachers' And Students' Perspectives Of Using Restorative Practices In Schools: "It's Got The Power To Change Behaviour", Michelle Kehoe Nov 2017

Teachers' And Students' Perspectives Of Using Restorative Practices In Schools: "It's Got The Power To Change Behaviour", Michelle Kehoe

Theses

In recent decades, there has been a shift away from authoritarian, punitive discipline in school communities and a movement towards approaches that promote inclusion, respectful relationships, and understanding. This shift was due to growing concerns about the negative impact of bullying and victimisation that was not resolved using traditional punitive measures. Whole-school restorative practices is an approach that has been reported as successful, in not only addressing misbehaviour as it occurs, but also as a preventive measure that builds social and emotional skills for all those within the school community.

The aim of this research was to explore teachers’ and ...


The Efficacy Of Cognitive-Behavioral Therapy For Eating Disorders: A Systematic Review And Meta-Analysis [Accepted Manuscript], Jake Linardon, Tracey Wade, Xochitl De La Piedad Garcia, Leah Brennan Nov 2017

The Efficacy Of Cognitive-Behavioral Therapy For Eating Disorders: A Systematic Review And Meta-Analysis [Accepted Manuscript], Jake Linardon, Tracey Wade, Xochitl De La Piedad Garcia, Leah Brennan

Faculty of Health Sciences Publications

Objective: This meta-analysis examined the efficacy of cognitive- behavioral therapy (CBT) for eating disorders. Method: Randomized controlled trials of CBT were searched. Seventy-nine trials were included. Results: Therapist-led CBT was more efficacious than inactive (wait-lists) and active (any psychotherapy) comparisons in individuals with bulimia nervosa and binge eating disorder. Therapist-led CBT was most efficacious when manualized CBT-BN or its enhanced version was delivered. No significant differences were observed between therapist-led CBT for bulimia nervosa and binge eating disorder and antidepressants at posttreatment. CBT was also directly compared to other specific psychological interventions, and therapist-led CBT resulted in greater reductions in ...


Emotion Regulation Strategies In Daily Life: Examining Contextual Variability In The Process Of Emotion Regulation, Robert N. Brockman Oct 2017

Emotion Regulation Strategies In Daily Life: Examining Contextual Variability In The Process Of Emotion Regulation, Robert N. Brockman

Theses

Contemporary theories of emotional well-being emphasize context as being inextricably linked to the process of emotion regulation. Empirical studies of these processes have generally relied upon single-occasion measurement approaches, but such methods are limited in their capacity to uncover regulatory processes that are inherently contextual and dynamic and that unfold over discrete time-periods. In this thesis, I address this gap using a daily process approach in three empirical studies to examine contextual variability in the usefulness of three popular emotion regulation strategies: mindfulness, cognitive reappraisal, and emotion suppression.

In Study 1, I establish a daily process approach as relevant to ...


Experiences Of Patients Who Have Undergone Bronchoscopy With ‘Cautious’ Sedation And Analgesia, Catherine Frances Saxon Oct 2017

Experiences Of Patients Who Have Undergone Bronchoscopy With ‘Cautious’ Sedation And Analgesia, Catherine Frances Saxon

Theses

Background

Bronchoscopy is a procedure that is used to investigate and treat respiratory conditions and disease. Sedation and analgesia are administered during the procedure to reduce the side effects of discomfort and cough. The use of sedation and analgesia is cautioned in patients with chronic obstructive pulmonary disease (a high-risk respiratory disease), due to the perceived increased risk of complications. A review of the associated literature examining adult patients’ experiences during flexible bronchoscopy found no qualitative articles on the subject. Due to the numerous quantitative survey-based studies, a significant gap in the literature was identified; that of the patient experience ...


Omics And Exercise: Global Approaches For Mapping Exercise Biological Networks [Accepted Manuscript], Nolan John Hoffman Oct 2017

Omics And Exercise: Global Approaches For Mapping Exercise Biological Networks [Accepted Manuscript], Nolan John Hoffman

Faculty of Health Sciences Publications

The application of global “omics” technologies to exercise has introduced new opportunities to map the complexity and interconnectedness of biological networks underlying the tissue-specific responses and systemic health benefits of exercise. This review will introduce major research tracks and recent advancements in this emerging field, as well as critical gaps in understanding the orchestration of molecular exercise dynamics that will benefit from unbiased omics investigations. Furthermore, significant research hurdles that need to be overcome to effectively fill these gaps related to data collection, computation, interpretation, and integration across omics applications will be discussed. Collectively, a cross-disciplinary physiological and omics-based systems ...


Psychotherapy For Bulimia Nervosa On Symptoms Of Depression: A Meta-Analysis Of Randomized Controlled Trials [Accepted Manuscript], Jake Linardon, Tracey Wade, Xochitl De La Piedad Garcia, Leah Brennan Oct 2017

Psychotherapy For Bulimia Nervosa On Symptoms Of Depression: A Meta-Analysis Of Randomized Controlled Trials [Accepted Manuscript], Jake Linardon, Tracey Wade, Xochitl De La Piedad Garcia, Leah Brennan

Faculty of Health Sciences Publications

Objective: Depressive symptoms are an important risk factor and consequence of binge eating and purging behavior in bulimia nervosa (BN). Although psychotherapy is effective in reducing symptoms of BN in the short- and long-term, it is unclear whether psychotherapy for BN is also effective in reducing depressive symptoms. This meta-analysis examined the efficacy of psychotherapy for BN on depressive symptoms in the short- and long-term. Method: Randomized controlled trials (RCTs) on BN that assessed depressive symptoms as an outcome were identified. Twenty-six RCTs were included. Results: Psychotherapy was more efficacious at reducing symptoms of depression at post-treatment (g = 0.47 ...


The Cognitive-Behavioural Theory And Treatment For Eating Disorders And Disordered Eating: A Direct Evaluation, Jake Linardon Sep 2017

The Cognitive-Behavioural Theory And Treatment For Eating Disorders And Disordered Eating: A Direct Evaluation, Jake Linardon

Theses

In a series of four studies, the aim of the current research project was to evaluate the cognitive-behavioral theory and treatment (CBT) of eating disorders. The first study (Chapter 5) was a meta-analysis (Linardon, Wade, De la Piedad Garcia, & Brennan, in press) of randomized controlled trials (RCT) testing the efficacy of CBT for eating disorders. Pooling data from 79 RCTs, results showed that therapist-led and guided self-help CBT were efficacious for individuals with bulimia nervosa (BN) and binge eating disorder (BED). There was no evidence to suggest that CBT was more efficacious than other psychological interventions in anorexia nervosa (AN).

Having found evidence supporting the efficacy of CBT for certain eating disorder presentations, the second study (Chapter 6), which was a systematic review, focused on identifying the reliable factors that mediate, moderate, or predict outcome during CBT (Linardon, de la Piedad Garcia, & Brennan, 2016b). This review found that mediators and moderators of change have been largely unexplored, and that no reliable predictors of outcome emerged. Therefore, based on existing evidence, it was concluded that it remains unclear how, for whom, and under what conditions, CBT for eating disorders works.

To understand the mechanisms through which CBT for eating disorders may work, a cross-sectional evaluation of the cognitive-behavioral model in a large non-clinical sample was employed for the third study (Chapter 8; under review). This study validated the conceptual pathways hypothesized by the cognitive model; it also identified two additional variables that might be important mechanisms of change during CBT, body checking and dichotomous thinking. The inclusion of body checking and dichotomous thinking within the cognitive-behavioral model explained nearly three times the amount of variance in disordered eating symptoms than the model without ...


Dynamics Of White Matter Plasticity Underlying Working Memory Training: Multimodal Evidence From Diffusion Mri And Relaxometry, Claudia Metzler-Baddeley, Sonya Foley, Silvia De Santis, Cyril Charron, Adam Hampshire, Karen Caeyenberghs, Derek Kenton Jones Sep 2017

Dynamics Of White Matter Plasticity Underlying Working Memory Training: Multimodal Evidence From Diffusion Mri And Relaxometry, Claudia Metzler-Baddeley, Sonya Foley, Silvia De Santis, Cyril Charron, Adam Hampshire, Karen Caeyenberghs, Derek Kenton Jones

Faculty of Health Sciences Publications

Adaptive working memory (WM) training may lead to cognitive benefits that are associated with white matter plasticity in parietofrontal networks, but the underlying mechanisms remain poorly understood. We investigated white matter microstructural changes after adaptive WM training relative to a nonadaptive comparison group. Microstructural changes were studied in the superior longitudinal fasciculus, the main parietofrontal connection, and the cingulum bundle as a comparison pathway. MRI-based metrics were the myelin water fraction and longitudinal relaxation rate R1 from multicomponent relaxometry (captured with the mcDESPOT approach) as proxy metrics of myelin, the restricted volume fraction from the composite hindered and restricted model ...


Exercise-Nutrient Interactions: Effects On Substrate Metabolism And Performance, Jill J. Leckey Sep 2017

Exercise-Nutrient Interactions: Effects On Substrate Metabolism And Performance, Jill J. Leckey

Theses

During prolonged (> 90 min), continuous steady-state exercise, skeletal muscle is fuelled by both carbohydrate (CHO) (i.e. muscle and liver glycogen, blood glucose and muscle, blood and liver lactate) and fat substrates (i.e. adipose and intramuscular triglycerides [IMTGs], blood-borne free fatty acids [FFAs] and TGs). The specific pattern of substrate oxidation is influenced by the relative exercise intensity, an individual’s training status and their preceding diet. However, it is well accepted that when exercising at high relative intensities (i.e. > 70% maximal oxygen uptake [V̇ O2max]), CHO-based fuels are the predominant fuel source. Despite CHO being important for ...


Targeting Reductions In Sitting Time To Increase Physical Activity And Improve Health [Accepted Manuscript], Sarah K. Keadle, David E. Conroy, Matthew P. Buman, David Wayne Dunstan, Charles E. Matthews Aug 2017

Targeting Reductions In Sitting Time To Increase Physical Activity And Improve Health [Accepted Manuscript], Sarah K. Keadle, David E. Conroy, Matthew P. Buman, David Wayne Dunstan, Charles E. Matthews

Faculty of Health Sciences Publications

New evidence suggests that reductions in sedentary behavior may increase physical activity and improve health. These findings point to new behavioral targets for intervention and new ways to think about intervening to increase overall physical activity in the population. This report provides a knowledge update reflecting the rapid accumulation of new evidence related to sedentary behavior and health among adults. Recent observational studies suggest that leveraging the time-inverse relationship between sedentary and active behaviors by replacing sitting with standing, light- or moderate-intensity activity can have important health benefits, particularly among less active adults. Clinical studies are providing evidence of the ...


The Adibox Study: Adiposity And Bone Metabolism: Effects Of Exercise-Induced Weight Loss In Adolescents With Obesity, Elodie Chaplais Aug 2017

The Adibox Study: Adiposity And Bone Metabolism: Effects Of Exercise-Induced Weight Loss In Adolescents With Obesity, Elodie Chaplais

Theses

Introduction: This program of research targeted the impact of an 8-month weight loss intervention induced by physical activity and nutrition on bone health in adolescents with obesity. The overall aim of this thesis was to examine the impact of a lifestyle weight loss intervention on the bone parameters in adolescents with obesity.

Method: Sixty-five adolescents were recruited: 31 (6 males) adolescents with obesity in the weight loss intervention (age: 13.61 (1.27)), 23 normal weight (NW) adolescents (age: 15.90 (0.43)) and 11 (4 males) adolescents with obesity in another control group (14.02 (1.39)). Primary outcomes ...


Associations Between Gait And Isometric Lower Limb Strength Following Stroke, Benjamin Frydlender Mentiplay Jul 2017

Associations Between Gait And Isometric Lower Limb Strength Following Stroke, Benjamin Frydlender Mentiplay

Theses

Stroke is a leading cause of disability worldwide. The most commonly stated goal following stroke is to regain the ability to walk independently, resulting in a large amount of rehabilitation time focussed on gait retraining. Identification of key variables that relate to and affect gait function is important in order to understand the factors associated with impaired gait and to guide future intervention strategies. Reduced muscle strength has been proposed as a key contributor to physical limitations after stroke and is commonly assessed in clinical and research settings. The aim of this thesis was to examine the associations between lower ...


Do Self-Managed Exercises And Strength/Fitness Training Affect Multifidus Muscle Size In Elite Footballers? [Accepted Manuscript], Julie Anne Hides, Jazmin C. Walsh, Melinda M. Franettovich Smith, M. Dilani Mendis Jul 2017

Do Self-Managed Exercises And Strength/Fitness Training Affect Multifidus Muscle Size In Elite Footballers? [Accepted Manuscript], Julie Anne Hides, Jazmin C. Walsh, Melinda M. Franettovich Smith, M. Dilani Mendis

Faculty of Health Sciences Publications

Context: Low back pain (LBP) and lower limb injuries are common among Australian Football League (AFL) players. Smaller size of 1 key trunk muscle, the lumbar multifidus (MF), has been associated with LBP and injuries in footballers. The size of the MF muscle has been shown to be modifiable with supervised motor-control training programs. Among AFL players, supervised motor-control training has also been shown to reduce the incidence of lower limb injuries and was associated with increased player availability for games. However, the effectiveness of a self-managed MF exercise program is unknown. Objective: To investigate the effect of self-managed exercises ...


Pilot Study To Determine The Feasibility Of Early Interventions For Ed Attendees Who Present With Moderate And High Levels Of Psychological Distress, Petra Lawrence Jun 2017

Pilot Study To Determine The Feasibility Of Early Interventions For Ed Attendees Who Present With Moderate And High Levels Of Psychological Distress, Petra Lawrence

Theses

Background

Mental health problems result in high levels of morbidity and mortality and impose high societal costs. Population surveys have not only revealed an increasing prevalence of mental illness and sub threshold levels of psychological distress within the community; but also, relatively consistent and unimproved levels of treatment-seeking behaviours. This unmet need for mental health interventions represents an important public health issue for global health care systems. The Emergency Department (ED) represents an ideal access point for hard to reach individuals and can be seen as a gateway to mental health services, particularly for individuals whom are not seeking treatment ...


Autophagy And Protein Turnover Responses To Exercise-Nutrient Interactions In Human Skeletal Muscle, William J. Smiles Jun 2017

Autophagy And Protein Turnover Responses To Exercise-Nutrient Interactions In Human Skeletal Muscle, William J. Smiles

Theses

Skeletal muscle is a dynamic tissue comprising the largest protein reservoir of the human body with a rate of turnover of ~1-2% per day. Protein turnover is regulated by the coordination of intracellular systems regulating protein synthesis and breakdown that converge in a spatiotemporal manner on lysosomal organelles responsible for integrating a variety of contractile and nutritional stimuli. One such system, autophagy, which literally means to ‘self-eat,’ involves capturing of cellular material for deliver to, and disintegration by, the lysosome. The autophagic ‘cargo’ is subsequently recycled for use in synthetic reactions and thus maintenance of protein balance. As a dynamic ...


Exploration Of Food Addiction In People Living With Schizophrenia [Accepted Manuscript], Ivana Goluza, Jay Borhard, Esther Kiarie, Judy Mullan, Nagesh Pai Jun 2017

Exploration Of Food Addiction In People Living With Schizophrenia [Accepted Manuscript], Ivana Goluza, Jay Borhard, Esther Kiarie, Judy Mullan, Nagesh Pai

Faculty of Health Sciences Publications

The term “food addiction” denotes a concept among researchers and lay consumers as a behavioural phenotype related to excessive food consumption. The concept is in parallel to clinical criteria for substance dependence and may aid in our understanding the psychological factors on weight gain (Hebebrand, Albayrak et al. 2014). While there is a lack of consensus whether the entity of food addiction constitutes as a true and valid addiction (Pai, Vella et al. 2014), the literature on food addiction has grown rapidly due to operationalization of the DSM-IV diagnostic criteria for substance dependence to eating behaviours utilising the Yale Food ...


European Society Of Cardiology - Acute Cardiovascular Care Association Position Paper On Safe Discharge Of Acute Heart Failure Patients From The Emergency Department [Accepted Manuscript], Òscar Miró, Frank W. Peacock, John J. Mcmurray, Hector Bueno, Michael Christ, Alan S. Maisel, Louise Cullen, Martin R. Cowie, Salvatore Di Somma, Francisco J. Martin Sanchez, Elke Platz, Josep Masip, Uwe Zeymer, Christiaan Vrints, Susanna Price, Alexandre Mebazaa, Christian Mueller Jun 2017

European Society Of Cardiology - Acute Cardiovascular Care Association Position Paper On Safe Discharge Of Acute Heart Failure Patients From The Emergency Department [Accepted Manuscript], Òscar Miró, Frank W. Peacock, John J. Mcmurray, Hector Bueno, Michael Christ, Alan S. Maisel, Louise Cullen, Martin R. Cowie, Salvatore Di Somma, Francisco J. Martin Sanchez, Elke Platz, Josep Masip, Uwe Zeymer, Christiaan Vrints, Susanna Price, Alexandre Mebazaa, Christian Mueller

Faculty of Health Sciences Publications

Heart failure is a global public health challenge frequently presenting to the emergency department. After initial stabilization and management, one of the most important decisions is to determine which patients can be safely discharged and which require hospitalization. This is a complex decision that depends on numerous subjective factors, including both the severity of the patient's underlying condition and an estimate of the acuity of the presentation. An emergency department observation period may help select the correct option. Ideally, during an observation period, risk stratification should be carried out using parameters specifically designed for use in the emergency department ...


The Relationship Between Physical Qualities And Activity Profiles Of International Women’S Sevens Players, Tyler Goodale Jun 2017

The Relationship Between Physical Qualities And Activity Profiles Of International Women’S Sevens Players, Tyler Goodale

Theses

Due to its inclusion in the recent Olympic Games, women’s Rugby Sevens has experienced a marked increase in popularity. As a result of the sports’ emergent nature the player profile and performance demands of women’s Rugby Sevens remain poorly understood.

Rugby Sevens is a modified game of 15-a-side Rugby Union, played under similar laws but with fewer players per side and for less total game time. The sport is played in a tournament format with multiple games played in one day and across a 2 to 3-day period. Rugby Sevens is one of the few true contact sports ...


Manipulation Of Muscle Creatine And Glycogen Changes Dxa Estimates Of Body Composition [Accepted Manuscript], Julia L. Bone, Megan L. Ross, Kristyen A. Tomcik, Nikki A. Jeacocke, Will G. Hopkins, Louise M. Burke, Louise M. Burke May 2017

Manipulation Of Muscle Creatine And Glycogen Changes Dxa Estimates Of Body Composition [Accepted Manuscript], Julia L. Bone, Megan L. Ross, Kristyen A. Tomcik, Nikki A. Jeacocke, Will G. Hopkins, Louise M. Burke, Louise M. Burke

Faculty of Health Sciences Publications

Standardizing a dual x-ray absorptiometry (DXA) protocol is thought to provide a reliable measurement of body composition.

Purpose: We investigated the effects of manipulating muscle glycogen and creatine content independently and additively on DXA estimates of lean mass.

Method: Eighteen well-trained male cyclists undertook a parallel group application of creatine loading (n = 9) (20 g·d−1 for 5 d loading; 3 g·d−1 maintenance) or placebo (n = 9) with crossover application of glycogen loading (12 v 6 g·kg−1 BM per day for 48 h) as part of a larger study involving a glycogen-depleting exercise protocol. Body ...


Consensus On A Specialist Clinical Learning And Teaching Framework For Australian Nurse Practitioners, Christopher Helms May 2017

Consensus On A Specialist Clinical Learning And Teaching Framework For Australian Nurse Practitioners, Christopher Helms

Theses

Background

The Australian nurse practitioner (NP) role is represented by over 1,400 endorsed NPs practising in over 50 different specialty areas. Generic standards have broadly supported the role’s behavioural, professional and expanded practice expectations since 2006, and have been used for the accreditation of NP Masters programmes nationally.

The need for consistent and flexible specialty clinical education for NP students has been described in the Australian literature. The clinical learning and teaching of Australian NP specialty roles has traditionally occurred in the student’s workplace, within a specified area of practice. Jurisdictional differences at state/territory and local ...


Psychometric Properties Of The Weight Self-Stigma Questionnaire (Wssq) Among A Sample Of Overweight/Obese French-Speaking Adolescents [Accepted Manuscript], Christophe Maiano, Annie Aimé, Geneviève Lepage, Aspq Team, Alexandre J. S. Morin Apr 2017

Psychometric Properties Of The Weight Self-Stigma Questionnaire (Wssq) Among A Sample Of Overweight/Obese French-Speaking Adolescents [Accepted Manuscript], Christophe Maiano, Annie Aimé, Geneviève Lepage, Aspq Team, Alexandre J. S. Morin

Faculty of Health Sciences Publications

Purpose: The Weight Self-Stigma Questionnaire (WSSQ) was recently developed to assess the internalization of weight stigma among English-speaking overweight and obese adults. The objective of the present study was to develop and examine the psychometric properties of a French version of the WSSQ, as well as its applicability to adolescents. Methods: The sample comprised 156 overweight and obese adolescents (81 boys, 75 girls, Mage = 16.31). The factor validity and the convergent validity of the French version of the WSSQ were examined using a confirmatory factor analysis and a structural equation model, respectively. Results: The a priori two-factor structure of ...


Antimicrobial Resistance In Urinary Tract Infections Caused By Escherichia Coli, Oyebola Fasugba Apr 2017

Antimicrobial Resistance In Urinary Tract Infections Caused By Escherichia Coli, Oyebola Fasugba

Theses

Urinary tract infections (UTI) are one of the most common bacterial infections in hospital and community settings requiring antimicrobial treatment. Escherichia coli (E. coli), a bacterium frequently implicated in UTI, is becoming increasingly resistant to antimicrobials. Antimicrobial resistance (AMR) reduces the effectiveness of antimicrobial agents, leading to difficulty in treatment of patients, with the potential to prolong the duration of illness and increase mortality in patients. To date in Australia, there is a paucity of data comparing resistance patterns over time for hospital- and community-acquired E. coli UTI with no published data on incidence and risk of urinary E. coli ...


Fathers’ Perinatal Mental Health: Impacts, Interventions And Supports, Holly Rominov Mar 2017

Fathers’ Perinatal Mental Health: Impacts, Interventions And Supports, Holly Rominov

Theses

Background. Fathers’ perinatal mental health problems have far reaching implications not only for themselves, but also for their partner, their couple relationship, and their children. The primary objective of this thesis by publication was to generate evidence to inform the development of policy and intervention efforts to promote fathers’ mental health in the perinatal period. The aims of the research were four-fold: first, to determine the extent to which fathers’ experiences of mental health problems impact parenting and their children; second, to undertake a systematic review into interventions targeting fathers’ perinatal mental health; third, to explore fathers’ support needs in ...


An Exploration Of End-Of-Life Care In The Intensive Care Unit: A Systematic Review Of Qualitative Studies Investigating The Experiences And Perceptions Of The Patient's Family, Alysia Coventry Feb 2017

An Exploration Of End-Of-Life Care In The Intensive Care Unit: A Systematic Review Of Qualitative Studies Investigating The Experiences And Perceptions Of The Patient's Family, Alysia Coventry

Theses

Background and aim: In the absence of rigorous evidence-based clinical guidelines, end-of-life care (EOLC) practices in the ICU vary considerably. Ideally, EOLC should be appropriately planned, implemented and informed by robust evidence; however the ICU is a setting where a patient’s health can deteriorate rapidly. Consequently, families (including family members, relatives and carers) are particularly vulnerable, and may experience shock, uncertainty and powerlessness in this technical and unfamiliar environment during EOLC. Families are optimally positioned to identify the key components of care at the end of life in the ICU, however their views and needs are under-represented in key ...


The Efficacy Of A Trunk Strengthening Program For Improving Postural Stability In People With Parkinson’S Disease: A Randomised Controlled Trial, Ryan Hubble Feb 2017

The Efficacy Of A Trunk Strengthening Program For Improving Postural Stability In People With Parkinson’S Disease: A Randomised Controlled Trial, Ryan Hubble

Theses

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by a series of motor and non-motor symptoms that collectively impact the independence and quality of life of this population. Symptoms of postural instability are amongst the most disabling and appear to be significantly influenced by a reduced capacity to control the trunk segment due to impaired trunk muscle function, muscle weakness and reduced inter-segmental mobility. Considering the trunk comprises approximately 60% of the body’s weight and that standard pharmacological therapies are known to be largely ineffective for the management of symptoms affecting this segment (i.e. axial symptoms), it ...


Gluteus Medius Activation During Running Is A Risk Factor For Season Hamstring Injuries In Elite Footballers [Accepted Manuscript], Melinda M. Franettovich Smith, Jason Bonacci, Marianne Dilani Mendis, Craig Christie, Andrew Rotstein, Julie Anne Hides Feb 2017

Gluteus Medius Activation During Running Is A Risk Factor For Season Hamstring Injuries In Elite Footballers [Accepted Manuscript], Melinda M. Franettovich Smith, Jason Bonacci, Marianne Dilani Mendis, Craig Christie, Andrew Rotstein, Julie Anne Hides

Faculty of Health Sciences Publications

To investigate if size and activation of the gluteal muscles is a risk factor for hamstring injuries in elite AFL players. Design Prospective cohort study. Methods Twenty-six elitemale footballers from a professional Australian Football League (AFL) club participated in the study. At the beginning of the season bilateral gluteus medius (GMED) and gluteus maximus (GMAX) muscle volume was measured from magnetic resonance images and electromyographic recordings of the same muscles were obtained during running. History of hamstring injury in the pre-season and incidence of hamstring injury during the season were determined from club medical data. Results Nine players (35%) incurred ...