Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Journal Articles (69)
- Bioethics (51)
- Clinical Trials (50)
- Research Subjects (48)
- Biomedical Research (42)
-
- Medical ethics (39)
- Human Experimentation (37)
- Risk Assessment (34)
- Informed Consent (32)
- Researcher-Subject Relations (29)
- Health (27)
- Medical Ethics (26)
- Placebos (25)
- Physician-Patient Relations (22)
- Research Ethics (21)
- Patient Rights (20)
- Research Design (18)
- Randomized Controlled Trials (15)
- Education (14)
- Therapeutic Human Experimentation (12)
- Cancer (10)
- Clinical trials (10)
- Developing Countries (10)
- Intervention (10)
- Nontherapeutic Human Experimentation (10)
- Practice (10)
- Cluster Randomized Trials (9)
- Controlled Clinical Trials (9)
- Dietary (9)
- Humans (9)
- Publication Year
- Publication
-
- Charles Weijer (158)
- Don C. Iverson (70)
- Peter Kelly (9)
- Xu-Feng Huang (9)
- Dr. Treena Orchard (8)
-
- Karen E. Charlton (8)
- Donald Morrow (6)
- Mitchell K Byrne (6)
- Alan Rothman (5)
- joseph Ciarrochi (5)
- Qingsheng Zhang (4)
- Richard G. Wamai (4)
- Dr Elizabeth Edwards (3)
- LeeAnn Bartolini (3)
- M. Therese Lysaught (3)
- Max J. Skidmore (3)
- Sharone Green (3)
- Anastasia Tsaliki (2)
- C. Barry Hoffmaster (2)
- Coralie J Wilson (2)
- Debbie Salas-Lopez MD, MPH (2)
- Donna M. Zucker (2)
- Dr Paul J Stapley (2)
- Jan Thomas (2)
- Stephanie Dixon (2)
- Andrew Blitman (1)
- Babette Babich (1)
- David T. Courtwright (1)
- Dr Sue Evans (1)
- Jessica Mantei (1)
Articles 331 - 341 of 341
Full-Text Articles in Medicine and Health Sciences
Monitoring Clinical Research: An Obligation Unfulfilled, Charles Weijer, Stanley Shapiro, Abraham Fuks, Kathleen Glass, Myriam Skrutkowska
Monitoring Clinical Research: An Obligation Unfulfilled, Charles Weijer, Stanley Shapiro, Abraham Fuks, Kathleen Glass, Myriam Skrutkowska
Charles Weijer
The revelation that data obtained for the US-based National Surgical Adjuvant Breast and Bowel Project (NSABP) from subjects enrolled at Hôpital Saint-Luc in Montreal was falsified has eroded public trust in research. Institutions can educate researchers and help prevent unethical research practices by establishing procedures to monitor research involving human subjects. Research monitoring encompasses four categories of activity: annual reviews of continuing research, monitoring of informed consent, monitoring of adherence to approved protocols and monitoring of the integrity of data. The authors describe characteristics of research projects that may call for monitoring procedures in each category. The form taken by …
Our Bodies, Our Science, Charles Weijer
The Breast Cancer Research Scandal: Addressing The Issues, Charles Weijer
The Breast Cancer Research Scandal: Addressing The Issues, Charles Weijer
Charles Weijer
The three claims put forward by Dr. Roger Poisson to rationalize his enrollment of ineligible subjects in clinical trials do not justify research fraud. None the less, certain lessons for the conduct of clinical research can be learned from the affair: experimental therapies should be made available to technically ineligible subjects when no effective therapy exists for their disease; further research must investigate the possible benefits of clinical-trial participation; broadly based, pragmatic trials must be regarded as the ideal model; and each eligibility criterion in a clinical-trial protocol should be justified.
Pulling The Plug On Futility, Charles Weijer, Carl Elliott
Pulling The Plug On Futility, Charles Weijer, Carl Elliott
Charles Weijer
No abstract provided.
Biomedical Ethics In A Canadian Context, Charles Weijer
Biomedical Ethics In A Canadian Context, Charles Weijer
Charles Weijer
No abstract provided.
Momento Mori, Charles Weijer
The Duty To Exclude: Excluding People At Undue Risk From Research, Charles Weijer, Abraham Fuks
The Duty To Exclude: Excluding People At Undue Risk From Research, Charles Weijer, Abraham Fuks
Charles Weijer
The clinical trial is the major investigational tool of clinical medicine. Two recent reports highlight the fact that the most often quoted mechanisms for the protection of research subjects, viz., research ethics board review and eligibility criteria, are insufficient to achieve this end. In this paper, we argue that the prime mechanism for the protection of persons in clinical trials should be the clinical judgement of the physician-investigator. The clinical investigator has a duty to protect subjects from both harm and undue risk. It is argued that the clinical investigator has a duty to screen for, and exclude, potential research …
Case Notes And Carting Of Bioethical Case Consultations, Benjamin Freedman, Charles Weijer, Eugene Bereza
Case Notes And Carting Of Bioethical Case Consultations, Benjamin Freedman, Charles Weijer, Eugene Bereza
Charles Weijer
In summary, the usual elements of a typical health care ethics consultation note might reasonably accommodate the needs and expectations of relevant parties, and would therefore include: 1. identification of the relevant ethical issues, questions, or dilemmas; 2. reference to any relevant facts--medical, nursing, social, psychological, spiritual, legal, political, etc.; 3. a prioritized list of recommendations to improve coordinated care; 4. a clear and concise articulation of relevant arguments, wtih specific reference to the list of recommendations as well as to the institution's overall ethos; 5. a contextual statement, identifying the perceived degree of consensus or support for the recommendations …
In Loco Parentis: Minimal Risk As An Ethical Threshold For Research Upon Children, Benjamin Freedman, Abraham Fuks, Charles Weijer
In Loco Parentis: Minimal Risk As An Ethical Threshold For Research Upon Children, Benjamin Freedman, Abraham Fuks, Charles Weijer
Charles Weijer
No abstract provided.
[Demarcating Research And Treatment Interventions: A Case Illustration]: Commentary, Benjamin Freedman, Charles Weijer
[Demarcating Research And Treatment Interventions: A Case Illustration]: Commentary, Benjamin Freedman, Charles Weijer
Charles Weijer
No abstract provided.
Family Medicine As A Social Science, Barry Hoffmaster
Family Medicine As A Social Science, Barry Hoffmaster
C. Barry Hoffmaster
The branch of clinical medicine most likely to qualify as a social science is family medicine. Whether family medicine is a social science is addressed in four steps. First, the nature of family medicine is outlined. Second, the extent to which social science knowledge is used in family practice is discussed. Third, the extent to which family medicine can qualify as a social science is considered with respect to an orthodox model of the social sciences, that is, one that emphasizes affinities between the natural and social sciences. Finally, the same question is addressed with respect to an unorthodox model …