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Full-Text Articles in Animal Experimentation and Research
Arkansas Animal Science Department Report 2013, David L. Kreider, Paul Beck
Arkansas Animal Science Department Report 2013, David L. Kreider, Paul Beck
Arkansas Agricultural Experiment Station Research Series
No abstract provided.
Late Developing Mammary Tumors And Hyperplasia Induced By A Low-Oncogenic Variant Of Mouse Mammary Tumor Virus (Mmtv) Express Genes Identical To Those Induced By Canonical Mmtv, Robert D. Bruno
Medical Diagnostics & Translational Sciences Faculty Publications
Background: The canonical milk-transmitted mouse mammary tumor virus (MMTV) of C3H mice (C3H-MMTV) rapidly induces tumors in 90% of infected animals by 8 months of age. Pro-viral insertions of C3H-MMTV into genomic DNA results in the overexpression of common core insertion site (CIS) genes, including Wnt1/10b, Rspo2, and Fgf3. Conversely, infection by either the endogenous Mtv-1 virus (in C3Hf) or the exogenous nodule-inducing virus (NIV) (in Balb/c NIV) induces premalignant mammary lesions and tumors with reduced incidence and longer latency than C3H-MMTV. Here, we asked whether Mtv-1/NIV affected the expression of core CIS genes.
Findings: We confirmed the presence of …
Arkansas Animal Science Department Report 2012, David L. Kreider
Arkansas Animal Science Department Report 2012, David L. Kreider
Arkansas Agricultural Experiment Station Research Series
No abstract provided.