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Animal Experimentation and Research Commons™
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Articles 1 - 9 of 9
Full-Text Articles in Animal Experimentation and Research
Does The Stress Inherent To Laboratory Life And Experimentation On Animals Adversely Affect Research Data?, Jarrod Bailey
Does The Stress Inherent To Laboratory Life And Experimentation On Animals Adversely Affect Research Data?, Jarrod Bailey
Validation of Animal Experimentation Collection
Stress and distress in laboratory animals is often inherent and unavoidable. The effect of these factors on the reliability and relevance of experimental data is not sufficiently appreciated. Greater awareness, debate and discussion of this issue are urgently required.
“Everyday” Knowledge And A New Paradigm Of Animal Research, David Fraser, Jeffrey M. Spooner, Catherine A. Schuppli
“Everyday” Knowledge And A New Paradigm Of Animal Research, David Fraser, Jeffrey M. Spooner, Catherine A. Schuppli
Validation of Animal Experimentation Collection
Commentary on Marino and Allen (2017) The Psychology of Cows
Addressing The Challenges Of Conducting Observational Studies In Sheep Abattoirs, Elyssa Payne, Melissa Starling, Paul Mcgreevy
Addressing The Challenges Of Conducting Observational Studies In Sheep Abattoirs, Elyssa Payne, Melissa Starling, Paul Mcgreevy
in Situ Research Models Collection
The competing needs of maintaining productivity within abattoirs, and maintaining high standards of animal welfare, provide fertile grounds for applied research in animal behavior. However, there are challenges involved in capturing useful behavioral data from the supply chain (from paddock to processing plant). The challenges identified in this report are based on a review of the scientific literature as well as field study observations. This article describes those challenges as they relate to collecting behavioral data on livestock-herding dogs, humans and livestock as they interact in abattoirs, and provides insights and recommendations for others embarking on animal studies in confined …
Wound Healing In Rabbit Corneas After Flapless Refractive Lenticule Extraction With A 345 Nm Ultraviolet Femtosecond Laser, Christian M. Hammer, Corinna Petsch, Jörg Klenke, Katrin Skerl, Christian Wüllner, Christof Donitzky, Friedrich Paulsen, Michael Scholz, Theo Seiler, Friedrich E. Kruse, Johannes Menzel-Severing
Wound Healing In Rabbit Corneas After Flapless Refractive Lenticule Extraction With A 345 Nm Ultraviolet Femtosecond Laser, Christian M. Hammer, Corinna Petsch, Jörg Klenke, Katrin Skerl, Christian Wüllner, Christof Donitzky, Friedrich Paulsen, Michael Scholz, Theo Seiler, Friedrich E. Kruse, Johannes Menzel-Severing
Biomedicine and Animal Models in Research Collection
Purpose
To characterize corneal wound healing in a rabbit model after flapless refractive lenticule extraction with a 345 nm ultraviolet femtosecond laser.
Setting
Departments of Ophthalmology and Anatomy II, University of Erlangen-Nürnberg and Wavelight GmbH, Erlangen, Germany.
Design
Methods
Flapless refractive lenticule extraction was performed in 1 eye each of 20 New Zealand white rabbits (−5.0 diopters). Groups of 4 animals were euthanized after 48 hours, 1 week, 2 weeks, 4 weeks, and 3 months, respectively. Corneal samples were prepared for histology and fluorescence microscopy. To assess corneal cell death, proliferation, and myofibroblastic transdifferentiation, terminal uridine deoxynucleotidyl nick end-labeling (TUNEL) …
Letter, Jarrod Bailey
Letter, Jarrod Bailey
Opposition to Animal Research Collection
In a recent publication in Lab Animal,1 a nonhuman primate (NHP) researcher at the California National Primate Research Center, USA, argued for the continued importance of experiments on macaques for better understanding HIV and AIDS, and for tackling the virus and the disease with therapies and vaccines. Though the stance of the author is far from surprising, given his background and current employer (an organisation which houses around 5000 monkeys for research), the paper, even as comprehensive as it is, is not sufficiently critical of NHP experiments and overlooks a number of their deficiencies and established problems with them. Given …
The European Politics Of Animal Experimentation: From Victorian Britain To ‘Stop Vivisection’, Pierre-Luc Germain, Luca Chiapperino, Giuseppe Testa
The European Politics Of Animal Experimentation: From Victorian Britain To ‘Stop Vivisection’, Pierre-Luc Germain, Luca Chiapperino, Giuseppe Testa
Attitudes Toward Animal Research Collection
This paper identifies a common political struggle behind debates on the validity and permissibility of animal experimentation, through an analysis of two recent European case studies: the Italian implementation of the European Directive 2010/63/EC regulating the use of animals in science, and the recent European Citizens' Initiative (ECI) 'Stop Vivisection'. Drawing from a historical parallel with Victorian antivivisectionism, we highlight important threads in our case studies that mark the often neglected specificities of debates on animal experimentation. From the representation of the sadistic scientist in the XIX century, to his/her claimed capture by vested interests and evasion of public …
Letter To The Editor, Jarrod Bailey
Letter To The Editor, Jarrod Bailey
Validation of Animal Experimentation Collection
It seems clear that heeding the opinions and recommendations of experienced neuroscientists such as Professor Beuter, the well-argued probable opinion of the time-travelling Parkinson, and Grimm and Eggel’s demands for high animal welfare and honest and realistic harm–benefit analyses, will be of paramount importance for the advancement and evolution of experiments involving NHPs, particularly in neuroscience. This will benefit animals and humans alike.
Refining The Precautionary Framework, Jonathan Birch
Refining The Precautionary Framework, Jonathan Birch
Animal Sentience
Most of the commentators so far agree that the precautionary principle can be usefully applied to the question of animal sentience. I consider various ways of refining my proposals in light of the suggestions. I amend BAR to implement C. Brown’s suggestion that the scope of animal welfare law should be extensible by phylogenetic inference from orders in which credible indicators of sentience are found. In response to C. Brown, Mallatt, and Woodruff, I amend ACT to allow that a single credible indicator may sometimes call for urgent further investigation rather than immediate protection. In response …
Animal Sentience And The Precautionary Principle, Jonathan Birch
Animal Sentience And The Precautionary Principle, Jonathan Birch
Animal Sentience
In debates about animal sentience, the precautionary principle is often invoked. The idea is that when the evidence of sentience is inconclusive, we should “give the animal the benefit of the doubt” or “err on the side of caution” in formulating animal protection legislation. Yet there remains confusion as to whether it is appropriate to apply the precautionary principle in this context, and, if so, what “applying the precautionary principle” means in practice regarding the burden of proof for animal sentience. Here I construct a version of the precautionary principle tailored to the question of animal sentience together with a …