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Full-Text Articles in Animal Experimentation and Research

Animal Experimentation: Working Towards A Paradigm Change, Kathrin Herrmann (Ed.), Kimberley Jayne (Ed.) Apr 2019

Animal Experimentation: Working Towards A Paradigm Change, Kathrin Herrmann (Ed.), Kimberley Jayne (Ed.)

eBooks

Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific …


Observing The Unwatchable Through Acceleration Logging Of Animal Behavior, Danielle D. Brown, Roland Kays, Martin Wikelski, Rory Wilson, A. Peter Klimley Dec 2013

Observing The Unwatchable Through Acceleration Logging Of Animal Behavior, Danielle D. Brown, Roland Kays, Martin Wikelski, Rory Wilson, A. Peter Klimley

Methodology and Animal Models in Research

Behavior is an important mechanism of evolution and it is paid for through energy expenditure. Nevertheless, field biologists can rarely observe animals for more than a fraction of their daily activities and attempts to quantify behavior for modeling ecological processes often exclude cryptic yet important behavioral events. Over the past few years, an explosion of research on remote monitoring of animal behavior using acceleration sensors has smashed the decades-old limits of observational studies. Animal-attached accelerometers measure the change in velocity of the body over time and can quantify fine-scale movements and body postures unlimited by visibility, observer bias, or the …


Systematic Review Of Chimpanzee Use In Monoclonal Antibody Research And Drug Development: 1981-2010, Raija Bettauer Jan 2011

Systematic Review Of Chimpanzee Use In Monoclonal Antibody Research And Drug Development: 1981-2010, Raija Bettauer

Experimentation Collection

This survey examines the extent to which live chimpanzees have been used in monoclonal antibody (mAb) research and the drug approval process. The survey covers 193 scientific articles published during the years 1981-2010, as well as preclinical studies leading to the approval of mAb drugs by the Food and Drug Administration of the United States. The frequency of the articles has decreased by more than two-thirds from their highs in the late 1980’s, and the aggregate number of chimpanzees used in these studies has decreased by more than 90%.

The experimental protocols ranged from single or multiple blood draws to …


The Ethical Limits Of Domestication: A Critique Of Henry Heffner’S Arguments, Colin Allen, Marc Bekoff, Lori Gruen Jan 2001

The Ethical Limits Of Domestication: A Critique Of Henry Heffner’S Arguments, Colin Allen, Marc Bekoff, Lori Gruen

Experimentation Collection

Henry E. Heffner argues that “animals bred for research are properly viewed as animals who have successfully invaded the laboratory niche, relying heavily on kin selection to perpetuate their genes.” (1999, p. 134). This view of human–animal interactions is the cornerstone of his defense of animal experimentation in two widely-distributed papers (Heffner 1999, 2001). We argue that Heffner’s defense lacks adequate attention to ethical distinctions and principles.


The Use Of Animals In Higher Education: Problems, Alternatives, & Recommendations, Jonathan Balcombe Jan 2000

The Use Of Animals In Higher Education: Problems, Alternatives, & Recommendations, Jonathan Balcombe

eBooks

Despite recent advances in technology and increasing societal concern for animals, animals continue to be exploited and killed in large numbers so that students can learn about their structure and function. Dissection may not be without its merits from an educational standpoint, if well implemented, but it appears from student surveys that it usually is not. When one considers the associated costs—animal suffering and death in the supply trade, disruption of wild animal populations, messages that tend to undermine rather than reinforce respect for life and concern for others, rising costs of animal carcasses (as compared with alternatives with longer …


Refinements In Rabbit Husbandry, The Bvaawf/Frame/Rspca/Ufaw Joint Working Group On Refinement Jan 1993

Refinements In Rabbit Husbandry, The Bvaawf/Frame/Rspca/Ufaw Joint Working Group On Refinement

Breeding of Laboratory Research Animals Collection

The aims of this report are to identify the needs of domesticated rabbits and to present information on ways in which the current systems of housing rabbits can be improved for the benefit of all concerned: the animal, the scientist, the animal technician and the breeder.

In recent years an increasing number of establishments have changed from standard caging to group housing systems, despite the traditionally-held view that mature rabbits cannot be housed together. In this report group housing in floor pens is discussed in detail (Section 2), with both the advantages and disadvantages of this system presented. It is …


Advances In Animal Welfare Science 1985/86, M. W. Fox (Ed.), A. N. Rowan (Ed.) Jan 1985

Advances In Animal Welfare Science 1985/86, M. W. Fox (Ed.), A. N. Rowan (Ed.)

eBooks

This second volume of papers dealing with scientific and ethical aspects of animal welfare covers a variety of topics and areas of investigation. It will be of particular interest to those readers seeking more insight into such subjects as farm animal welfare and humane husbandry systems; animal experimentation, especially in the field of psychology; and pain in animals, notably its recognition and alleviation.


Breeding And Use Of Nonhuman Primates In The Usa, Joe R. Held Jan 1981

Breeding And Use Of Nonhuman Primates In The Usa, Joe R. Held

International Journal for the Study of Animal Problems

Several species of nonhuman primates, each possessing specific characteristics of particular value, are used by the United States biomedical community in various health-related activities. These animals are man's closest relatives and are indispensable in understanding and controlling human health problems. The destruction of primate habitats and embargoes on the export of primates from source countries have decreased the supply of these animals. The inadequate and erratic supply of these resources threatens the continuation of many ongoing and new activities contributing to improving human health. In the U.S., a program has been developed to meet the health needs of primates:

1) …


Breeding And Use Of Nonhuman Primates In The Usa, Joe R. Held Jan 1981

Breeding And Use Of Nonhuman Primates In The Usa, Joe R. Held

Experimentation Collection

Several species of nonhuman primates, each possessing specific characteristics of particular value, are used by the United States biomedical community in a wide variety of health-related activities. These animals are man's closest relatives and are indispensable in the effort to understand and control human health problems.

The destruction of primate habitats and embargoes on export of primates from source countries have decreased the supply of these animals. Continuation of many ongoing and new activities contributing to the improvement of human health is threatened by inadequate and erratic supply of these resources. In the U.S., a program has been developed to …


Ethology And Laboratory Animal Welfare, James A. Cohen Nov 1980

Ethology And Laboratory Animal Welfare, James A. Cohen

International Journal for the Study of Animal Problems

No abstract provided.