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Full-Text Articles in Animal Experimentation and Research

Ld50: A Cruel Waste Of Animals Mar 1983

Ld50: A Cruel Waste Of Animals

Close Up Reports

Imagine a test in which up to 100 animals are forced to consume a toxic substance in an amount high enough to kill half of them. Then imagine that the explicit purpose of the test is to kill those animals. Incredibly, such a test not only exists but each year also claims the lives of from two to four million animals.

The test is the lethal dose 50, or LD50 as it's commonly called. Its purpose is to measure the toxicity of a substance by determining how much of that substance will kill half of a group of some 60-100 …


The Ld50--The Beginning Of The End, Andrew N. Rowan Jan 1983

The Ld50--The Beginning Of The End, Andrew N. Rowan

Experimentation Collection

Measurement is very important in science. Early lessons in the science classroom involve teaching students to measure lengths, volumes, weights, specific gravities and anything else within the mental and economic compass of the teacher. At the same time, the question of significance is drummed into the students' heads. Thus, if one has a meter-rule which is subdivided into centimeters (but not millimeters), one is taught that the measurement of its length to one decimal point (for example, 10.3 em) is acceptable, but that the addition of any more figures (for example, 10.325 em) is mere braggadocio. The eye can only …