Plant Pathology Commons^™

Predicting Transcriptional Responses To Cold Stress Across Plant Species, Xiaoxi Meng, Zhikai Liang, Xiuru Dai, Yang Zhang, Samira Mahboub, Daniel W. Ngu, Rebecca Roston, James Schnable

Center for Plant Science Innovation: Faculty and Staff Publications

Although genome-sequence assemblies are available for a growing number of plant species, gene-expression responses to stimuli have been cataloged for only a subset of these species. Many genes show altered transcription patterns in response to abiotic stresses. However, orthologous genes in related species often exhibit different responses to a given stress. Accordingly, data on the regulation of gene expression in one species are not reliable predictors of orthologous gene responses in a related species. Here, we trained a supervised classification model to identify genes that transcriptionally respond to cold stress. A model trained with only features calculated directly from genome …