Physiology Commons^™

Therapeutic Potential Of Insulin-Sensitizing Drugs In The Treatment Of Prostate Cancer With Coexisting Obesity, Alison Schwein, Mong-Hong Lee, Sai-Ching Yeung

International Journal of Exercise Science: Conference Proceedings

TITLE: Insulin-sensitizing Drugs to Treat Obese Prostate Cancer Patients

AUTHORS: Alison Schwein, B.S.1, Dr. Mong-Hong Lee PhD2, Dr. Sai-Ching Yeung PhD, MD2

AFFILIATIONS: 1University of Texas Graduate School of Biomedical Sciences, 2M.D. Anderson Cancer Center

Purpose: Prostate cancer (PC) in obese men is more likely to cause a more aggressive disease that recurs after radical prostatectomy than in non-obese men; also, risks of advanced PC or death from PC are increased when associated with obesity. The biological mechanisms underlying the association between obesity and the progression of PC have yet to be established. Insulin resistance is associated with obesity. Insulin …

Evaluation Of Metabolic Stress Between Jumping At Different Cadences On The Digi-Jump Machine, Thomas S. Lyons, James W. Navalta, Zachary J. Callahan

International Journal of Exercise Science

The American College of Sports Medicine (ACSM) recommends that healthy adults achieve a minimum of thirty minutes of moderate intensity aerobic exercise five days per week. While cycling, walking, and jogging are commonly observed methods of achieving these recommendations, another option may be repetitive jumping. The purpose of this study was to examine the metabolic responses between repetitive jumping at a cadence of 120 jumps per minute (JPMs) vs. 100 JPMs when utilizing the Digi-Jump machine. Twenty-eight subjects completed two jumping trials, one at 120 JPMs and one at 100 JPMs. Subjects jumped until volitional exhaustion, or for a maximum …

The Association Between Soft Drink Consumption And Body Fat In Females Age 16 To 24, Megan M. Costello, Kate A. Heelan, Deborah A. Mowry, Bryce Abbey

International Journal of Exercise Science

American soft drink consumption (SDC) has increased since the 1960’s surpassing all other kinds of beverage consumption. In recent years, the scientific literature has suggested that SDC has been linked to the rising epidemic of obesity in children and adolescents. However, there is lack of information in scientific literature on the effects of SDC on body fat (BF%) in young females. The purpose of this study was to determine the association between SDC and BF% in young women, ages 16-24 years. Sixty-six females were asked to complete a 3-day food record, food frequency questionnaire, and an assessment BF% by dual-energy …

Resistance And Aerobic Training Sequence Effects On Energy Consumption In Females, Rachael Cutts, Steve Burns

International Journal of Exercise Science

Purpose: The objective of this study was to investigate the effect of sequence of resistance and aerobic training on energy consumption on sedentary overweight females. Methods: Participants were 15 sedentary overweight females (age = 28.6 ±12 yrs; BMI = 28.1±7.8) Subjects did a counterbalanced intervention: resistance training (circuit training) first (intervention RT) or aerobic exercise first (intervention AT), while oxygen consumption was continuously measured for 80 min. Subjects performed a warm-up on the treadmill at 40% of their heart rate reserve for 5 minutes, then for 30 minutes did continuous walking or jogging on the treadmill at ~67% of their …

The Effects Of Niacin And Aerobic Exercise In Postmenopausal Women Glucose, Insulin And C-Peptide Profiles, Heidi Bidstrup, Yunsuk Koh, James Rowe, David Nichols, Vic Ben-Ezra, Kyle Biggerstaff

International Journal of Exercise Science: Conference Proceedings

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A Culturally Friendly Web-Based Hybrid Intervention To Prevent Obesity: The Salsa Study, Scherezade K. Mama, Ashley V. Medina, Raul Orlando Edwards, Lorna Mcneill, Ygnacio Lopez Iii, Rebecca E. Lee

International Journal of Exercise Science: Conference Proceedings

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Effects Of Chocolate Milk Supplementation On Recovery From Cycling Exercise And Subsequent Time Trial Performance, Lisa Ferguson-Stegall, Erin Mccleave, Phillip G. Doerner Iii, Zhenping Ding, Benjamin Dessard, Lynne Kammer, Bei Wang, Yang Liu, John L. Ivy

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Supplementing with carbohydrate plus protein following strenuous endurance exercise has been found to improve both recovery and subsequent aerobic endurance performance beyond that of a carbohydrate supplement alone. The purpose of the present study was to compare the effects of chocolate milk (CM), an isocaloric carbohydrate only supplement (CHO), and placebo (PLA) on markers of endurance exercise recovery and subsequent time trial performance in trained cyclists. METHODS: Ten trained male and female cyclists (5 males, 5 females) performed 3 trials in which they first cycled for 1.5 h at 70% of VO2max, followed by 10 min of intervals that …

The Effects Of Pre- And Post-Exercise Whey Vs. Casein Protein Consumption On Body Composition And Performance Measures In Collegiate Female Athletes, Kristin M. Dugan, Mallory Mcadams, Morgan Lewing, Cliffa Foster, Colin Wilborn, Lemuel W. Taylor Iv

International Journal of Exercise Science: Conference Proceedings

Two of the most popular forms of protein on the market are whey and casein. Both proteins are derived from milk however the two differ concerning their absorption in the body. This difference between whey and casein proteins could affect the response seen in conjunction with training. PURPOSE: To investigate the potential effects of two types of protein ingestion in conjunction with a controlled resistance training program utilizing college female basketball players. METHODS: 16 NCAA Division III female basketball players were matched according to weight and double-blind randomly assigned to consume 24 grams whey protein (WP) (N = 8, 20 …

Effect Of A Low Carbohydrate-Moderate Protein Supplement On Endurance Performance In Female Athletes, Erin L. Mccleave, Lisa Ferguson-Stegall, Zhenping Ding, Phillip Doerner, Bei Wang, Lynne Kammer, John L. Ivy

International Journal of Exercise Science: Conference Proceedings

Previous research has shown that consuming a carbohydrate supplement during prolonged endurance exercise improves performance compared to water or placebo. The addition of protein to traditional carbohydrate supplement has been shown to further improve perfomance beyond that of carbohydrate alone. However, few investigations have explored the effect of adding protein to a supplement containing a low carbohydrate concentration. PURPOSE: To investigate if a low carbohydrate and moderate protein supplement, provided during prolonged variable intensity exercise, would improve time to exhaustion in comparison to a traditional carbohydrate supplement. METHODS: Fourteen (n = 14) trained females cyclists and triathletes (30.4 ±1.6 yrs, …

Partial Weightbearing At 1/6 And 1/3 G Does Not Prevent Deleterious Changes In Bone Observed With Traditional Tail Suspension (0 G), Sarah Luna, Josh Swift, Yasaman Shirazi-Fard, M Lucas, Florence Lima, Liz Greene, Harry Hogan, Susan Bloomfield

International Journal of Exercise Science: Conference Proceedings

The effect of partial gravity (G) (as on the Lunar surface) on weight bearing bone remains undefined; a new model (the partial G mouse) provides for graded reductions in weight bearing. We hypothesized that mice exposed to 1/6th G and 1/3rd G (to mimic Lunar weightbearing with full spacesuit) will experience significant reductions in cortical and cancellous bone mass as compared to ambulatory control animals but that the magnitude of these changes would be less than in 0 G mice. Methods: Fifty-eight BALB/cBy female mice were randomly assigned to cage control (1G), “zero-gravity” hindlimb unloaded (0G), 1/6th gravity (G/6), or …

Serum Il-6 Is Increased During Performance Cycling After Energy Drink Consumption, Jonathan Woodson, Melody Phillips, Jacob Ross, Kelyn Rola, Kenneth Christensen

International Journal of Exercise Science: Conference Proceedings

Energy Drinks (ED) have become popular preexercise supplements due to the stimulant effects of their ingredients such as caffeine. Other ingredients including carbohydrate (CHO), glucuronolactone and taurine may also contribute to performance enhancement. Purpose: The purpose of this study was to investigate the influence of energy drink consumption on cycling performance, substrate oxidation and immune-related variables. Methods: This study was a blinded, randomized, cross-over design with 3 experimental conditions. Eleven trained male cyclists (mean age 33.4±8.9 yr, body mass 81±7.6 kg, VO2max 51.72±3.4 ml*kg-1*min-1) consumed 3 different 500 ml beverages: 1) Energy Drink (ED1- 2.0g taurine, 1.2 g glucoronolactone, 160 …

Modeling Oxygen Uptake During V1 Treadmill Roller Skiing, Robert S. Bowen†, Randall L. Jensen‡, Jennifer M. Ryan†, Phillip B. Watts‡

International Journal of Exercise Science

The use of regression equations to predict oxygen uptake in relation to speed, grade, power output, and anthropometric characteristics is common in cardiac rehabilitation and athlete fitness testing. Research has suggested that sport specific testing improves the reliability of the test methodology and is appropriate for the development of effective training programs. This study focused on the development of a cross-country skiing specific predictor of maximal oxygen uptake based on treadmill speed, treadmill grade, gender, and body mass. This project simulated snow skiing on a large research treadmill using roller skis. A small sample size (N = 34) warranted the …

Timing Carbohydrate Beverage Intake During Prolonged Moderate Intensity Exercise Does Not Affect Cycling Performance, George G. Schweitzer†, John D. Smith‡, James D. Lecheminant‡

International Journal of Exercise Science

Carbohydrate beverages consumed during long-term exercise have been shown to attenuate fatigue and improve performance; however, the optimal timing of ingestion is unclear. Therefore, the purpose of this study was to determine if timing the carbohydrate ingestion (front-loading (FL), continual loading (CL), and end-loading (EL)) during prolonged exercise influenced exercise performance in competitive cyclists. Ten well-trained cyclists completed three separate exercise bouts on a bicycle ergometer, each lasting 2 hours at an intensity of ~67% VO₂ max, followed by a 15-minute “all out” time trial. In the FL trial, participants ingested a carbohydrate beverage during the first hour and …

Aerobic Capacity And Postprandial Flow Mediated Dilation, Kevin D. Ballard†, James J. Miller‡, James H. Robinson†, Jennifer L. Olive‡

International Journal of Exercise Science

The consumption of a high-fat meal induces transient vascular dysfunction. Aerobic exercise enhances vascular function in healthy individuals. Our purpose was to determine if different levels of aerobic capacity impact vascular function, as measured by flow mediated dilation, following a high-fat meal. Flow mediated dilation of the brachial artery was determined before, two- and four-hours postprandial a high-fat meal in young males classified as highly trained (n = 10; VO2max = 74.6 ± 5.2 ml·kg·min-1) or moderately active (n = 10; VO2max = 47.3 ± 7.1 ml·kg·min-1). Flow mediated dilation was reduced at two- (p < 0.001) and four-hours (p < 0.001) compared to baseline for both groups but was not different between groups at any time point (p = 0.108). Triglycerides and insulin increased at two- (p < 0.001) and four-hours (p < 0.05) in both groups. LDL-C was reduced at four-hours (p = 0.05) in highly trained subjects, and two- and four-hours (p ≤ 0.01) in moderately active subjects. HDL-C decreased at two- (p = 0.024) and four-hours (p = 0.014) in both groups. Glucose increased at two-hours postprandial for both groups (p = 0.003). Our results indicate that a high-fat meal results in reduced endothelium-dependent vasodilation in highly trained and moderately active individuals with no difference between groups. Thus, high aerobic capacity does not protect against transient reductions in vascular function after the ingestion of a single high-fat meal compared to individuals who are moderately active.