Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Physiology
Neural And Humoral Control Of Regional Vascular Beds Via A1 Adenosine Receptors Located In The Nucleus Of The Solitary Tract, Joseph Martin Mcclure
Neural And Humoral Control Of Regional Vascular Beds Via A1 Adenosine Receptors Located In The Nucleus Of The Solitary Tract, Joseph Martin Mcclure
Wayne State University Dissertations
Previous studies from our laboratory showed that activation of NTS A1 adenosine
receptors yields variable hemodynamic responses with prevailing pressor and iliac
vasoconstrictor responses. These responses are accompanied with differential
activation of regional sympathetic activity (adrenal>>renal≥lumbar) and inhibition of
baroreflex mechanisms at the level of the NTS. The variability of the hemodynamic
responses was a result of simultaneous Β-adrenergic vasodilation counteracted with
sympathetic and unknown humoral vasoconstriction. Among many potential
vasoconstrictors vasopressin, angiotensin II and circulating norepinephrine were
considered. Therefore, blood pressure and iliac vascular responses evoked by
selective stimulation of NTS A1 adenosine receptors (CPA 330 …