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Toxicology Commons

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Full-Text Articles in Toxicology

The Toxicology Of Aluminum In The Brain: A Review, Robert A. Yokel Oct 2000

The Toxicology Of Aluminum In The Brain: A Review, Robert A. Yokel

Pharmaceutical Sciences Faculty Publications

Aluminum is environmentally ubiquitous, providing human exposure. Usual human exposure is primarily dietary. The potential for significant Al absorption from the nasal cavity and direct distribution into the brain should be further investigated. Decreased renal function increases human risk of Al-induced accumulation and toxicity. Brain Al entry from blood may involve transferrin-receptor mediated endocytosis and a more rapid process transporting small molecular weight Al species. There appears to be Al efflux from the brain, probably as Al citrate. There is prolonged retention of a fraction of Al that enters the brain, suggesting the potential for accumulation with repeated exposure. Al …


Integronlike Structures In Campylobacter Spp. Of Human And Animal Origin, Brigid Lucey, D. Crowley, P. Moloney, B. Cryan, M. Daly, F. O'Halloran, E. J. Threlfall, S. Fanning Feb 2000

Integronlike Structures In Campylobacter Spp. Of Human And Animal Origin, Brigid Lucey, D. Crowley, P. Moloney, B. Cryan, M. Daly, F. O'Halloran, E. J. Threlfall, S. Fanning

Department of Biological Sciences Publications

Resistance to antimicrobial agents used to treat severe Campylobacter spp. gastroenteritis is increasing worldwide. We assessed the antimicrobial resistance patterns of Campylobacter spp. isolates of human and animal origin. More than half (n = 32) were resistant to sulphonamide, a feature known to be associated with the presence of integrons. Analysis of these integrons will further our understanding of Campylobacter spp. epidemiology.


Ambient Toxicity Of Water Samples From Four Locations In The Elizabeth River : A Comparison Of Species Sensitivities, Morris H. Roberts, Peter F. De Lisle Jan 2000

Ambient Toxicity Of Water Samples From Four Locations In The Elizabeth River : A Comparison Of Species Sensitivities, Morris H. Roberts, Peter F. De Lisle

Reports

In the present study, the objective was to evaluate four species for relative sensitivity when challenged with ambient water from four locations in the Elizabeth River, ranging from locations considered to be free of toxicity to an area known to have copper concentrations that exceeded water quality standards in past sampling.