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Toxicology Commons

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Full-Text Articles in Toxicology

Behavioral Alterations Following Exposure To A Mixture Of Lead And Atrazine During Early Development In The Zebrafish Model System, Anusha Kv Lakshmi Dharmavathi Nov 2022

Behavioral Alterations Following Exposure To A Mixture Of Lead And Atrazine During Early Development In The Zebrafish Model System, Anusha Kv Lakshmi Dharmavathi

The Journal of Purdue Undergraduate Research

Lead (Pb) and atrazine (ATZ) are hazardous environmental toxicants that can exist as a mixture in potable water. Numerous single chemical studies on Pb and ATZ support adverse health outcomes, including neurotoxicity, but mixture studies are limited. Th e aim of this study is to test the hypothesis that Pb and ATZ mixtures result in a greater than additive toxicity, causing increased adverse health outcomes than single chemical exposures. Th e zebrafish model system was exposed to 3 or 30 ppb (µg/L) ATZ, 10 ppb (equivalent to 0.1 µg/dL) or 100 ppb Pb, along with mixtures of each beginning at …


Sustainable Building, Spring/Summer 2009, Issue 20 Sep 2019

Sustainable Building, Spring/Summer 2009, Issue 20

Sustain Magazine

No abstract provided.


Urban Regeneration, Fall/Winter 2003, Issue 7 Sep 2019

Urban Regeneration, Fall/Winter 2003, Issue 7

Sustain Magazine

No abstract provided.


Characterizing The Impacts Of Contaminants On Fish Embryogenesis And Revealing An Alternate Molecular Mechanism Of Ahr Mediated Cardiac Defects, Corinna Singleman Jun 2017

Characterizing The Impacts Of Contaminants On Fish Embryogenesis And Revealing An Alternate Molecular Mechanism Of Ahr Mediated Cardiac Defects, Corinna Singleman

Dissertations, Theses, and Capstone Projects

There is a long history of damage to natural ecosystems from environmental pollution. Many environmental contaminants are man-made and have been released with abandon over the last 100 years including dioxins, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and polychlorinated biphenyls (PCBs). These chemicals act on similar cellular processes and cause skin lesions, cancer, learning disabilities and reproductive problems in many vertebrates. There are many studies exploring various aspects of TCDD and PCB exposure on model and wild organisms. Few studies however, have compared effects of PCB mixtures on ecosystems to effects of individual PCBs in the lab. The first aim of this thesis is …