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Full-Text Articles in Toxicology
Do Environmental Toxins Predict Violent Crimes?, Tyler Stahl
Do Environmental Toxins Predict Violent Crimes?, Tyler Stahl
Symposium of Student Scholars
Do chemical pollutants that persistent in the environment and bioaccumulate in the body affect human health and behavior? Could these Persistent, Bioaccumulative, and Toxic (PBT) chemicals play a role in the cause of violent crimes due to deterioration of mental and cognitive functions? In the past, Mercury, a PBT chemical, has been shown in salmon to be associated with aggression. Could similar aggression occur in humans exposed to mercury through a toxic spill? Two sources of data are utilized in this analysis. The Environmental Protection Agency’s (EPA) Annual Toxic Release Inventory publishes data on toxic releases into the environment and …
Assessing The Effects Of Chemical Mixtures Using A Bayesian Network-Relative Risk Model (Bn-Rrm) Integrating Adverse Outcome Pathways (Aops), Valerie Chu, Meagan J. Harris, Scarlett Graham, Lindsay K. Wallis, Chelsea Mitchell, John D. Stark, Katherine Von Stackelberg
Assessing The Effects Of Chemical Mixtures Using A Bayesian Network-Relative Risk Model (Bn-Rrm) Integrating Adverse Outcome Pathways (Aops), Valerie Chu, Meagan J. Harris, Scarlett Graham, Lindsay K. Wallis, Chelsea Mitchell, John D. Stark, Katherine Von Stackelberg
Graduate Student Symposium
There are long-standing uncertainties about toxicity of chemical mixtures to populations. Laboratory toxicity tests have confirmed synergistic and antagonistic effects to individuals, but not to populations.We will conduct a regional scale ecological risk assessment by evaluating the effects chemical mixtures to populations with a new Bayesian Network- Relative Risk Model (BN-RRM) incorporating an Adverse Outcome Pathway (AOP). We started applying this new BN-RRM framework in a case study with organophosphate pesticide mixtures (diazinon, chlorpyrifos, and malathion). Acetylcholinesterase inhibition (AChE) was chosen the molecular initiating event and the Puget Sound Chinook salmon (Oncorhynchus tshawytscha) and Coho salmon (Oncorhynchus kisutch …