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Pharmacology, Toxicology and Environmental Health Commons

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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Exposure Characterization And Assessment Of Airborne Chemicals And Sars-Cov-2 Transmission In New York City Nail Salons, Amelia P. H. Watkins Jun 2021

Exposure Characterization And Assessment Of Airborne Chemicals And Sars-Cov-2 Transmission In New York City Nail Salons, Amelia P. H. Watkins

Dissertations and Theses

Background: Currently, there are 156,000 people employed as manicurists or pedicurists in the United States. Employment in this sector is expected to grow by 10% over the next decade. Exposure assessments have revealed that salon workers are chronically exposed to a variety of substances that cause respiratory sensitization, developmental problems, contact dermatitis, blood, liver, and kidney issues, as well as nervous system impacts. Most recently, the SARS-Cov-2 pandemic has raised the issue of the vulnerability of nail salon workers to airborne infectious diseases as well. This dissertation aims to characterize and assess the chemical exposures that nail salon workers …


Nebulizer-Based Systems To Improve Pharmaceutical Aerosol Delivery To The Lungs, Benjamin M. Spence Jan 2021

Nebulizer-Based Systems To Improve Pharmaceutical Aerosol Delivery To The Lungs, Benjamin M. Spence

Theses and Dissertations

Combining vibrating mesh nebulizers with additional new technologies leads to substantial improvements in pharmaceutical aerosol delivery to the lungs across therapeutic administration methods. In this dissertation, streamlined components, aerosol administration synchronization, and/or Excipient Enhanced Growth (EEG) technologies were utilized to develop and test several novel devices and aerosol delivery systems. The first focus of this work was to improve the poor delivery efficiency, e.g., 3.6% of nominal dose (Dugernier et al. 2017), of aerosolized medication administration to adult human subjects concurrent with high flow nasal cannula (HFNC) therapy, a form of continuous-flow non-invasive ventilation (NIV). The developed Low-Volume Mixer-Heater (LVMH) …


Understanding Of Aerosol Transmission Of Covid 19 In Indoor Environments, Adama Barro, Cathal O'Toole, Jacob S. Lopez, Matthew Quinones, Sherene Moore Dec 2020

Understanding Of Aerosol Transmission Of Covid 19 In Indoor Environments, Adama Barro, Cathal O'Toole, Jacob S. Lopez, Matthew Quinones, Sherene Moore

Publications and Research

Our reason for discussing severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) or 2019 novel corona virus (Covid-19), is to understand its aerosol transmission characteristics in indoor spaces and to mitigate further spread of this disease by designing a new HVAC system. The problem that we are tackling is the spread of covid-19 droplets through aerosol transmission by looking at potential engineering solutions to the existing HVAC systems. The purpose is to eradicate the spread of the COVID-19 by testing indoor spaces in an effort to understand the effectiveness of ventilation controls. We believe that scientists and engineers have not …


Ventilation & Masks: Reducing Airborne Transmission Of Covid-19 In A Classroom, Eric A. Schiff Aug 2020

Ventilation & Masks: Reducing Airborne Transmission Of Covid-19 In A Classroom, Eric A. Schiff

SyracuseCoE Research Brief Series

We've calculated the number of COVID-19 infections that will be spread from a single COVID-19 "superspreader" to students and teachers in a classroom shared for 4 hours in different ventilation and masking conditions.


Experimental Validation Of The Multiple-Zone System Ventilation Efficiency Equation Of Ansi/Ashrae Standard 62.1 (1276-Rp), David P. Yuill, Grenville K. Yuill, Andrew H. Coward May 2012

Experimental Validation Of The Multiple-Zone System Ventilation Efficiency Equation Of Ansi/Ashrae Standard 62.1 (1276-Rp), David P. Yuill, Grenville K. Yuill, Andrew H. Coward

David Yuill

This article describes an experiment that was carried out on an existing building to test the validity of the system ventilation efficiency equation for multiple-zone recirculating systems of ANSI/ASHRAE Standard 62.1. The system ventilation efficiency equation (SVEE) can be applied to buildings that use a recirculating air distribution system. It accounts for the fact that the return air carries some “unused” outdoor air, so that the amount of new outdoor air introduced at the air handler can be reduced. The SVEE is based on a mass balance but infiltration and interzonal mixing are not included in the formulation. Since infiltration …