Other Life Sciences Commons^™

An Ecological Study Of The Spotted Salamander, Ambystoma Maculatum, And Jefferson Salamander, A. Jeffersonianum, In West Virginia, Seth J. Myers

Theses, Dissertations and Capstones

The movements of Spotted Salamanders, Ambystoma maculatum, and Jefferson Salamanders, A. jeffersonianum, in and out of an ephemeral wetland in West Virginia were monitored for one breeding season using a drift fence lined with funnel traps. Significant movements of A. jeffersonianum coincided with rainfall and maximum daily air temperatures reaching a minimum of 5° C. Significant movements of A. maculatum coincided with rainfall and maximum daily air temperatures of at least 10° C. A. jeffersonianum preceded A. maculatum to the breeding site. Males of both species preceded females. The mark-recapture estimate of A. maculatum is 67 males and 25 females. …

Phosphoproteomic Studies Of Smooth Muscle Contraction: Investigation Of Differential Phosphorylation In Relaxed/Contracted Rat Aortic Smooth Muscle Tissue Using Maldi-Tof Ms, Tonya M. Pekar

Theses, Dissertations and Capstones

Many human disorders are associated with the malfunction of smooth muscle tissue, or are related to the capabilities of its proper function—asthma, glaucoma, renal inefficiency, hypertension, and cardiovascular disease. Dysfunctional proteins are frequently implicated as the source of such disorders. As the second highest cause of death in the United States, the epidemic of cardiovascular disease makes the study of smooth muscle of utmost concern.

The capabilities of proteomics and mass spectrometry allow the entire proteome complement of a cell or tissue type to be analyzed at once. This investigation employs such techniques in an effort to better understand the …