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Full-Text Articles in Human and Clinical Nutrition
The Effect Of Vitamin D3 Supplementation On Advanced Glycation End Products, (Ages) And Soluble Receptor, (Srage) In African Americans And Hispanics With Type 2 Diabetes And Vitamin D Insufficiency/Deficiency, Justina Serwaah Owusu
FIU Electronic Theses and Dissertations
There is a high burden of diabetes and its related complications globally. Advanced Glycation End Products (AGEs) and their receptors have been implicated in complications and mortality related to type 2 diabetes (T2D). Vitamin D deficiency, prevalent in persons with T2D, increases oxidative stress and inflammation that promotes the formation of AGEs.
This study assessed the relationship between sRAGE and AGEs and risk of cardiovascular diseases (CVD) and the effect of vitamin D3 supplementation on levels of AGEs and soluble receptor (sRAGE) in adults with hypovitaminosis D. African Americans and Hispanics (n=64) were recruited in Miami and were supplemented with …