Human and Clinical Nutrition Commons^™

Impact Of Bodyweight On Tissue-Specific Folate Status, Genome Wide And Gene-Specific Dna Methylation In Normal Breast Tissues From Premenopausal Women, Armina-Lyn Frederick

Masters Theses

Obesity has reached an epidemic level in the United States. A number of epidemiological studies have established obesity as a critical risk factor for postmenopausal breast cancer (post-BC), whereas a reverse association holds prior to menopause. A significant scientific gap exists in understanding the mechanism(s) underpinning this epidemiological phenomenon, particularly the reverse association between obesity and premenopausal breast cancer (pre-BC). This study aimed to understand how folate metabolism and DNA methylation informs the association between obesity and pre-BC. Fifty normal breast tissue samples were collected from premenopausal women who underwent reduction mammoplasty. We developed and measured the breast tissue folate …

Desert Within A City: Exploring The Relationship Between Food Security, Diet, And Body Mass Index, Jamey Ann Baietto

Theses and Dissertations

Background: Food deserts are areas of decreased access to nutritious and affordable foods. Residing within a defined food desert is thought to decrease consumption of produce, dairy, and whole grains and increase consumption of energy-dense foods as well as body mass index (BMI).

Objective: The purpose of this study was to determine the effects of the level of food security on consumption of fruits, vegetables, dairy, whole grains, high-sugar foods, high-fat foods, and BMI.

Design: A one-time, self-administered data collection packet was sent to residents of a food desert. The Dietary Screener Questionnaire was utilized to determine the average daily …