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Developmental Neuroscience Commons

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James Madison University

Projections.

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Full-Text Articles in Developmental Neuroscience

Targeting Of Central Nucleus Projections To Extramodular Zones Of The Lateral Cortex Of The Inferior Colliculus In Developing Mouse, Isabel D. Lamb-Echegaray May 2018

Targeting Of Central Nucleus Projections To Extramodular Zones Of The Lateral Cortex Of The Inferior Colliculus In Developing Mouse, Isabel D. Lamb-Echegaray

Senior Honors Projects, 2010-2019

The multimodal lateral cortex of the inferior colliculus (LCIC) exhibits a modular-extramodular micro-organization that is evident early in development. In addition to a set of neurochemical markers that reliably highlight its modular-extramodular organization, mature projection patterns in a variety of adult species suggest that major LCIC afferents also recognize and adhere to such a framework. This patch-matrix-like arrangement appears to segregate into distinct afferent streams, with somatosensory inputs targeting LCIC modules and auditory inputs targeting surrounding extramodular zones. Currently lacking is a detailed understanding of the development and shaping of multimodal LCIC afferents with respect to its modular-extramodular framework. The …