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Behavioral Neurobiology Commons

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Full-Text Articles in Behavioral Neurobiology

Associations Between Hypothalamic-Pituitary-Adrenal Axis System Gene Variants And Cortisol Reactivity In Preschoolers: Main Effects And Gene-Environment Interactions, Haroon I. Sheikh Jun 2014

Associations Between Hypothalamic-Pituitary-Adrenal Axis System Gene Variants And Cortisol Reactivity In Preschoolers: Main Effects And Gene-Environment Interactions, Haroon I. Sheikh

Electronic Thesis and Dissertation Repository

Exposure to stressful events during early development has consistently been shown to produce long lasting effects on the hypothalamic-pituitary-adrenal (HPA) axis, which may increase vulnerability to mood and anxiety disorders. Recently reported genetic association studies indicate that these disorders may be influenced, in part, by gene-environment interactions (GxE) involving polymorphisms within the corticotrophin-releasing hormone and monoaminergic system genes. However, little is known about how genetic variants and life stress work to shape children’s neuroendocrine reactivity and emerging symptoms. Therefore, the aim of this thesis is to examine main effects of candidate genes and GxE on the neuroendocrine stress response and …


Effects Of Light On Flight Crew Health And Alertness; Study Results Revealed, Lori Brown Mar 2014

Effects Of Light On Flight Crew Health And Alertness; Study Results Revealed, Lori Brown

Lori Brown

Portable bright light units, the Boeing Alertness Model (BAM) and Jeppessen Crew Alert application have been introduced in a field study with long haul pilots and cabin crew in ground breaking research – which may lead to improvements in aviation safety through the development of new preventive alertness strategies. Western Michigan University, Novair Airlines, Nature Bright, Jeppesen Crew Alert and leading sleep scientists collaborated to examine whether timed blue light integrated with the Boeing Alertness Model will improve alertness, and mitigate cognitive fatigue. The CrewAlert application and timed light puts innovative preventative fatigue strategies in the palm of the crew …