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Full-Text Articles in Behavioral Neurobiology
Alcohol Consumption In A Preclinical Model Of Schizophrenia, Liza Hernandez
Alcohol Consumption In A Preclinical Model Of Schizophrenia, Liza Hernandez
Electronic Theses and Dissertations
Schizophrenia is a debilitating psychiatric disorder that affects approximately 1% of the global population. Schizophrenia is highly comorbid with other psychiatric disorders such as Alcohol Use Disorder (AUD) with a prevalence rate of 27% - 65%, which is significantly higher than AUD exhibited by the general population (6%). Research indicates that a higher rate of AUD in individuals suffering from schizophrenia may be related to the common neuronal pathways that underlie the expression of both disorders. The present study will determine whether the neonatal quinpirole (NQ) rodent model of schizophrenia will approximate the human condition and exhibit increased EtOH consumption. …