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Articles 1 - 6 of 6
Full-Text Articles in Behavioral Neurobiology
Investigation Of Neurotransmitter’S Knockdown Effect On Drosophila Melanogaster Female Aggression, Asil N. El Galad
Investigation Of Neurotransmitter’S Knockdown Effect On Drosophila Melanogaster Female Aggression, Asil N. El Galad
Undergraduate Student Research Internships Conference
Drosophila melanogaster (D. melanogaster) is a popular model organism in neurobiology. While aggression has been studied heavily in male drosophila, there's minimal research on aggression in female drosophila. Neurotransmitters influencing aggressive behaviour in female D. melanogaster are poorly understood. Various neurotransmitters such as dopamine, octopamine, and serotonin influence aggression in D. melanogaster Further investigation of the role of neurotransmitters on aggression is thus important. The purpose of our experiment is to observe the effect of the knockdown of dopamine, octopamine and glutamate on aggression in female D. melanogaster.
Assessing The Impact Of Lipopolysaccharide On Learning And Memory In Rats, Anahat Luthra
Assessing The Impact Of Lipopolysaccharide On Learning And Memory In Rats, Anahat Luthra
Undergraduate Student Research Internships Conference
The immune system and the central nervous system (CNS) have a bi-direction relationship, modulating one another.4 Proinflammatory cytokines released from CNS immune cells have an impact on cognitive processes such as learning and memory.1 Liposaccharide (LPS), a cell wall component of Gram-negative bacteria, which is used to activate proinflammatory cytokine release has been found to impact learning and memory processes, such as in the anticipatory nausea paradigm (ANP).2 Anticipatory nausea and vomiting is that which may occur before a chemotherapy treatment session begins in a patient who has had chemotherapy before. It is caused by triggers like …
130— Reducing Stereotypic Behavior With A Ketogenic Diet, Anna Beltramini, Andrew Guido, Alicia Bauers, Joe Spano
130— Reducing Stereotypic Behavior With A Ketogenic Diet, Anna Beltramini, Andrew Guido, Alicia Bauers, Joe Spano
GREAT Day Posters
Now a popular fad diet, the ketogenic diet (KD) is a high-fat, low-carb diet that for decades has been used for treatment of intractable epilepsy. Recent therapeutic applications of KD in animal models include treatment of dementia, obsessive-compulsive disorder, and autism. These disorders are associated with stereotypic behaviors (repetitive, invariant behaviors with no apparent function) that are life-impairing and stigmatizing. However, little is known about their underlying mechanisms and no effective pharmacological treatments are available. Here, we present a novel application of KD to reduce stereotypic behavior in an inbred strain of mice (FVBN/J) that displays a prominent repetitive circling …
159— The Effects Of Trauma On The Response To Cocaine, Gavin Vaughan, Melissa Herman, Katie Kompanijec, Maren Hogan, Annaclaire Modico, Keara Mullin, Allison R. Bechard Ph.D.
159— The Effects Of Trauma On The Response To Cocaine, Gavin Vaughan, Melissa Herman, Katie Kompanijec, Maren Hogan, Annaclaire Modico, Keara Mullin, Allison R. Bechard Ph.D.
GREAT Day Posters
Exposure to adverse events is a risk factor for substance use disorder. We modeled this in an inbred strain of mice by exposing adult males to a predator odor (a synthetic fox pheromone, TMT) and then assessing 1. Cocaine-induced locomotion, and 2. Conditioned place preference (CPP) of cocaine. TMT was an effective stressor as indicated by freezing behavior, an absence of movement that is an instinctive fear response in mice. Interestingly, in a 1-hour baseline locomotor test, TMT-exposed (TMT+) mice were more active than non-exposed (TMT-) mice. In addition, following a cocaine (10 mg/kg) injection (i.p.) TMT+ mice showed a …
161— The Effects Of Environment On The Development Of Cocaine-Seeking, Gavin Vaughan, Akane Ichiki, Shreyya Malik, Allison R. Bechard
161— The Effects Of Environment On The Development Of Cocaine-Seeking, Gavin Vaughan, Akane Ichiki, Shreyya Malik, Allison R. Bechard
GREAT Day Posters
Cocaine addiction is a major individual and societal issue. This study aimed to investigate the environmental and social factors that influence the development of cocaine addiction. Mice were reared in either standard housing or enriched housing. Cocaine preference was measured using the Conditioned Place Preference paradigm, in which subjects are conditioned to associate an injection of cocaine (20mg/kg. I.P.) with a particular side of a 3 chambered arena. Subjects reared in enriched environments displayed increased preference for cocaine in cue primed tests. All subjects displayed cocaine preference in cocaine primed tests. This may be attributed to the enhanced memory that …
Contextual Fear Learning And Memory In Alternative Stress Coping Styles, Matthew R. Baker, Ryan Y. Wong
Contextual Fear Learning And Memory In Alternative Stress Coping Styles, Matthew R. Baker, Ryan Y. Wong
UNO Student Research and Creative Activity Fair
Animals frequently must overcome stressors, and the ability to encode and recall these salient experiences is essential to an individual’s survival. Across many taxa, studies have documented two alternative stress coping styles (proactive and reactive) that differ in behavior, cognition, stress physiology, and underlying neuromolecular mechanisms. The role of stress in cognitive traits (e.g. learning and memory) has been well documented, however, the influence of an animal’s stress coping style on learning and memory capabilities is only beginning to be understood. Here, we developed a contextual fear learning paradigm to characterize learning and memory differences between proactive and reactive stress …