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Behavioral Neurobiology Commons

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Dissertations & Theses (Open Access)

Theses/Dissertations

Dopamine

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Full-Text Articles in Behavioral Neurobiology

Identification And Delineation Of Neuronal Pathways Underlying Hypophagia, Jing Cai Dec 2023

Identification And Delineation Of Neuronal Pathways Underlying Hypophagia, Jing Cai

Dissertations & Theses (Open Access)

In terms of metabolism, eating disorders manifest in two extreme directions: overnutrition, which can lead to obesity, and malnutrition, which can result in underweight or even starvation. Both extremes compromise the quality of life. According to the Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) standard, eating disorders affect up to 17.9% of young women and 2.4% of young men. Although eating disorders are primarily defined as mental disorders rather than metabolic disorders, they are intertwined with complex emotions and sensory perceptions. However, in contemporary animal research related to eating disorders and feeding behaviors, the majority of neuroscientists still examine …


Role Of Dopamine Of Nucleus Accumbens In Behavioral Sensitization To Methylphenidate, Sheshali J. Wanchoo May 2010

Role Of Dopamine Of Nucleus Accumbens In Behavioral Sensitization To Methylphenidate, Sheshali J. Wanchoo

Dissertations & Theses (Open Access)

Behavioral sensitization is defined as the subsequent augmentation of the locomotor response to a drug following repeated administrations of the drug. It is believed to occur due to alterations in the motive circuit in the brain by stressors, central nervous system stimulants, and similar stimuli. The motive circuit (or mesocorticolimbic system) consists of several interconnected nuclei that determine the behavioral response to significant biological stimuli. A final target of the mesocorticolimbic system is the nucleus accumbens (NAc), which is a key structure linking motivation and action. In particular, the dopaminergic innervations of the Nac are considered to be essential in …